Journal of Biomedical Nanotechnology
·
2021
·Vol. 17
·期 5
·921-931
·
IF 4.099
Ming Yang,Yu Yan,Yang Cheng-Li,Chen Xin-Mian,Han Ru-Xia,Hao Ying,Hu Dan-Rong,Pan Meng,Zhou Xiao-Han,Qian Zhi-Yong
Phenylketonuria (PKU) is a common disease associated with amino acid metabolism, and usually occurs in newborns. It can cause serious neurological diseases and even death. However, owing to inadequate-effective treatment, it can only be slowed by a low-phenylalanine (Phe) diet. In addition,
PKU screening is essential for newborns in many countries. Therefore, rapid screening is crucial for preventing damage and meeting the large sample diagnosis demand. For confirmed patients, a convenient method to monitor their regular Phe levels is required. However, current clinical methods
do not meet the rapid screening and convenient monitoring requirements. Herein, a rapid and facile electrochemical device based on platinum-doped reduced graphene oxide nanocomposites was developed to detect PKU biomarker-Phe. The results demonstrated that the developed electrode has great
sensitivity, selectivity, and stability. The detection range was 0.0001 mM to 6 mM with a limit of detection of 0.01 μM. Therefore, this work offers a simple and rapid method for point-of-care PKU screening and daily monitoring.
研究领域:
医学
·
生物化学
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DOI
PubMed
高影响因子
CHEMOSPHERE
·
2016
·
IF 3.698
Yiqun Chen,Pinya Deng,Pengchao Xie,Ran Shang,Zongping Wang,Songlin Wang
We evaluated the degradation of methylparaben (MeP) and ethylparaben (EtP), two representative parabens, using the heat-activated persulfate system in a laboratory. Both sulfate and hydroxyl radicals contributed to the removal of the two parabens. The degradations of both MeP and EtP were improved by increasing the heating temperature or persulfate dose in accordance with a pseudo-first-order reaction model. The oxidation efficiency of parabens was found to be pH-dependent; decreasing in the order pH 5.0 > 7.0 > 9.0. The presence of chloride, bicarbonate , or humic acid was found to inhibit the degradation of the two parabens to some extent because of competition for the reactive radicals, with humic acid having the most serious effect. Dealkylation of the methyl unit, decarboxylation of the carboxylic group, and subsequent hydrolysis are proposed to be involved in the degradation pathway of MeP. The results suggest that the heat-activated persulfate system might be efficiently applied in the treatment of paraben-containing water samples. This was also supported by the results of applying this system to treat a real water sample containing both MeP and EtP.
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2016
·
IF 2.693
Zhanlong Zheng,Jiayi Zhu,Yutie Bi,Yewei Xu,Qianfeng Zhang,Xing Zhang,Junjiang Li,Lin Zhang
A novel wavelength shifter of the 1,4-bis(4-methoxylstyryl)benzene (bis-4-MOSB) was synthesized by employing the classical Horner-Wadsworth-Emmons reaction. Feasible analysis of the bis-4-MOSB as the wavelength shifter in a ternary liquid scintillator, in which p-xylene (PX) was as the solvent and 2,5-diphenyloxazole (PPO) was as the primary fluor, was carried out. The optimum prescription with 3.5 g/L PPO and 25 mg/L bis-4-MOSB was obtained with regard to the light yield. A series of characterization tests based on the optimal formulation were performed. Compared with the 1,4-bis(2-methylstyryl)benzene (bis-MSB), the maximum absorption peak at 356 nm and maximum emission peak at 421 nm in n-hexane with the red shift of 10 nm and 3 nm, respectively, were measured accordingly. The light yield characterized by using a relative measurement method achieved as high as 75.85% of the anthracene crystal. A brief density functional calculation was conducted to have an insight into the electronic structure characteristic of the bis-4-MOSB in the scintillation process.
研究领域:
化学
·
物理学
✓ 已验证
DOI
高影响因子
Journal of Sulfur Chemistry
·
2020
·
IF 1.963
Lin Yan,Jun Yang,Xu-Feng Liu,Yu-Long Li,Xing-Hai Liu,Zhong-Qing Jiang
In this article, two new binuclear iron compounds [Fe2(CO)5PPh(C6H11)2{µ-SCH2CH(CH2CH3)S}] (2) and [Fe2(CO)5PPh2(C6H11){µ-SCH2CH(CH2CH3)S}] (3), which can be regarded as the biomimics for the active site of [FeFe]-H2ases, have been synthesized by CO exchange of compound [Fe2(CO)6{μ-SCH2CH(CH2CH3)S}] (1) with cyclohexyldiph-enylphosphine or dicyclohexylphenylphosphine and their structures have been confirmed by spectroscopy, elemental analysis, and X-ray crystallography. They also exhibited good electrocatalytic activities for the generation of H2.
研究领域:
无机化学
·
材料科学
·
生物无机化学
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DOI
高影响因子
CHROMATOGRAPHIA
·
2025
·
IF 1.3
Huang Zhongping,Zou Jianfeng,Zhang Junhao,Wang Haodong,Liu Huijun
In this study, quaternized cationic polyelectrolytes were successfully decorated on polystyrene-divinylbenzene (PS-DVB) microspheres in deep eutectic solvents (DESs). Quaternized cationic polyelectrolytes and hyperbranched layers were prepared using 1,4-butanediol diglycidyl ether (BDDE) and methylamine (MA) as monomers. The effects of different reaction solvents, the amount of agglomerated polyelectrolytes, and the number of hyperbranched layers on the chromatographic performance of the stationary phase were investigated. The surface morphological feature and chemical composition of the PS-DVB microspheres were characterized by SEM, FT-IR, and elemental analysis. The results showed that the optimized anion exchanger had a good chromatographic performance by choosing a mixture of 2.0 mmol/L sodium carbonate and 2.0 mmol/L sodium bicarbonate as the mobile phase at a flow rate of 1.0 mL/min. Seven common anions (fluoride ion, chloride ion, nitrite ion, bromide ion, nitrate ion, phosphate ion, and sulfate ion) were well separated within 25 min. The average numbers of theoretical plates per meter for three batches of columns prepared in DESs increased by 5% ~ 20%, as compared with those of the columns prepared in deionized water. Additionally, the asymmetry factors of detected anions were also improved for the columns prepared in DESs.
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产品关联
DOI
高影响因子
Nanoscale
·
2014
·Vol. 6
·期 10
·5223-5229
·
IF 6.739
Xiaojun Liu,Ligui Li,Meixia Ye,Yang Xue,Shaowei Chen
Gold nanoparticles were stabilized by a polyaniline:poly(sodium 4-styrenesulfonate) (PANI:PSS) matrix and readily dispersed in water over a wide range of pH. In contrast to nanoparticles passivated by alkanethiolates that formed a compact capping layer on the nanoparticle surface, the PANI:PSS–Au nanocomposites exhibited apparent catalytic activity in the reduction of 4-nitrophenol in the presence of excessive NaBH4, with reasonably good recyclability, which was likely due to the large accessible surface area. In addition, the PANI:PSS–Au nanocomposites also demonstrated peroxidase-like catalytic activity as evidenced by the colorimetric detection of H2O2 and glucose with PANI:PSS–Au as the enzymatic mimic. The present method may find potential applications in the design, preparation and functionalization of noble nanoparticles as efficient, versatile, and recyclable catalysts with high dispersibility and stability in aqueous media.
研究领域:
材料科学
·
催化化学
·
纳米技术
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DOI
PubMed
高影响因子
MATERIALS & DESIGN
·
2022
·
IF 9.417
Yao Huang,Tong Liu,Lingwei Ma,Jinke Wang,Dawei Zhang,Xiaogang Li
In this work, a triple-action self-healing coating was fabricated to promote the corrosion protection of carbon steel based on a shape memory polymer (SMP) epoxy coating and polyaniline/benzotriazole (PANI/BTA) nanocapsules. The PANI/BTA nanocapsules had dual functions: (1) PANI as a saline (NaCl)-responsive gatekeeper could achieve the controllable release of BTA corrosion inhibitors, which could adsorb on the metal surface to inhibit corrosion; (2) PANI can prompt the formation of Fe 2 O 3 passive layer. Besides, the thermo-responsive SMP coating could narrow the scratch size after heating, which was beneficial to reduce the amount of corrosion inhibitors needed to fully cover the steel surface. Electrochemical impedance spectroscopy (EIS) measurements were performed to investigate the self-healing performance of the coatings containing different contents of PANI/BTA nanocapsules. Furthermore, the synergetic inhibition effects of PANI, BTA and SMP coating were demonstrated using scanning electrochemical microscopy. The results indicated that the healed 0.5 wt% PANI/BTA coating exhibited an excellent self-healing property and its self-healing efficiency was higher than 96%. The XPS results indicated that the Fe 2 O 3 passive layer was formed in the scratched region to resist steel corrosion.
研究领域:
材料科学
·
腐蚀与防护
·
电化学
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DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2017
·
IF 4.339
Miaomiao Liu,Weiqiang Tang,Yisheng Xu,Hongbo Yu,Hongfeng Yin,Shuangliang Zhao,Shenghu Zhou
Pd-SnO 2 heteroaggregate nanocatalysts were synthesized by in-situ transformation of PdSn bimetallic nanoparticles on alumina. The PdSn bimetallic nanoparticles were prepared by co-reduction of Pd and Sn precursors. The obtained PdSn nanoparticles possibly have a core-shell like structure with Pd cores and Sn-rich shells due to the fast reduction of Pd precursors. The Pd-SnO 2 /Al 2 O 3 heteroaggreagte nanocatalysts were synthesized by calcination of PdSn/Al 2 O 3 in air followed by H 2 reduction. Various characterization techniques, such as HRTEM, XRD and XPS, were used to characterize the PdSn and Pd-SnO 2 . The Pd 3 -(SnO 2 ) 1 /Al 2 O 3 heteroaggreagte nanocatalysts with a ratio of Pd/Sn of 3/1 illustrated enhanced catalytic performances for p -nitroacetophenone and p -nitrobenzaldehyde hydrogenations relative to monometallic Pd nanocatalysts. Theoretical calculations using density functional theory suggested that Pd-SnO 2 facilitates the adsorption of reactants in a higher degree than that of products, thus enhancing the catalytic activity even with partial coverage of Pd surfaces with SnO 2 . The blockage effect of SnO 2 on Pd surfaces is speculated to enhance the catalytic selectivity for p -nitroacetophenone and p -nitrobenzaldehyde hydrogenations over Pd-SnO 2 heteroaggregate nanocatalysts.
研究领域:
催化化学
·
材料科学
·
理论计算
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DOI
高影响因子
EUROPEAN JOURNAL OF MASS SPECTROMETRY
·
2016
·
IF 1.011
Shanshan Wang,Guohua Zhu,Mengmeng Chen,Jinsong Liu,Kezhi Jiang
p-Chloroaniline is one of the banned aromatic amines in azo dyes, but it is very difficult to distinguish it from its isomers due to their identical retention time in chromatography and similar mass spectra. In this work, derivatization of the isomeric chloroanilines was carried out to yield the corresponding N-tosyl chloroanilines, which were completely separated by gas chromatography and also possessed clearly different electron ionization mass spectra. Thus, the three isomers could be differentiated and determined at the same time. Density functional theory calculation results indicated that the effect of the substituent pattern in electron ionization mass spectrometry is mainly due to the difference in the stability of the product ion (P2) at m/z 126, originating from the loss of tosyl radical from the precursor ion.
研究领域:
分析化学
·
染料工业
·
环境科学
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DOI
PubMed
高影响因子
RSC Advances
·
2022
·Vol. 12
·期 7
·4234-4239
·
IF 4.036
Dandan Li,Chengyang Wang,Xiaoying Yan,Shengqi Ma,Ran Lu,Chunhai Chen,Guangtao Qian,Hongwei Zhou
To obtain high thermostable materials for flexible display substrates, a series of copoly(benzimidazole imide)s was prepared using 5-amine-2-(4-aminobenzene)-1-phenyl-benzimidazole (N-PhPABZ) and 6(5)-amino-2-(4-aminobenzene)-benzimidazole (PABZ). Incorporating N-phenyl groups effectively healed the brittleness of the poly(benzimidazole imide)s (PBIIs) derived from pyromellitic dianhydride (PMDA), and the resultant homo- and copoly(benzimidazole imide)s displayed an outstandingly high glass transition temperature (Tg > 450 °C) and a low coefficient of thermal expansion (CTE < 10 ppm K−1). Furthermore, the influence of removing intermolecular hydrogen bonds on the properties of these poly(benzimidazole imide)s was systematically analyzed. These data provide a feasible method to prepare superheat-resistant poly(benzimidazole imide)s without H-bonding.
研究领域:
材料科学
·
高分子化学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Jiangwei Ma,Huiqing Fan,Zhexin Li,Yuxin Jia,Arun Kumar Yadav,Guangzhi Dong,Weijia Wang,Wenqiang Dong,Shuren Wang
The flexible room-temperature gas sensors are highly desirable to apply in wearable and portable equipment owing to their wearability. The research mainly focuses on the gas-sensing materials and few studies paid attention to the conjunction between flexible substrates and sensing materials. In this work, the polyethylene terephthalate (PET) fibers substrate is modified by ethylenediamine (EDA) to expose the amino group on the surface (PET-NH 2 ). This method is simple, cost-efficient, and easy to operate. The positively charged amino group could interact with negatively charged carboxyl (−COOH) of multi-walled carbon nanotubes (MWCNTs) by electrostatic attraction. The EDA treatment on PET effectively strengthens the connection between the flexible PET substrate and gas sensing materials with carboxyl as evidenced by SEM images. After the in situ polymerization process, the polyaniline (PANI) is successfully decorated on the MWCNTs. The fabricated PET-NH 2 -MWCNTs/PANI sensor exhibits strongly enhanced ammonia (NH 3 ) sensing performance as compared to the PET-MWCNTs/PANI sensor without the EDA treatment. The results suggest that the EDA treatment is an effective method to conjunct between flexible substrates and sensing materials, which shows great potential in the field of flexible gas sensors.
研究领域:
材料科学
·
传感器技术
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Xiaowen Xie,Xiaoguo Ma,Lihui Guo,Yinming Fan,Guolong Zeng,Mengyuan Zhang,Jing Li
A novel multi-templates molecularly imprinted polymer (MIP) was prepared on the surface of mesoporous silica coated magnetic graphene oxide (MGO@mSiO 2 ), and applied for the rapid and selective detection of alkylphenol compounds including bisphenol A (BPA), 4-tert-octylphenol (4-tert-OP) and 4-nonylphenol (4-NP) in water. The synthesized composite was characterized by Fourier transform infrared spectrometer, vibrating sample magnetometer, transmission electron microscopy and Brunauer-Emett-Teller surface area analyzer. The MIP showed high adsorption capacity, good selectivity and fast kinetic for these alkylphenols. The maximum adsorption capacities of the MIP for BPA, 4-tert-OP and 4-NP were 16.81, 35.97 and 61.73 mg g −1 , respectively, which were significantly higher than those of the non-molecularly imprinted polymer (NIP) due to the imprinting effect. The adsorption of alkylphenols reached equilibrium within 30 min, and followed pseudo-second-order kinetic model and Langmuir model well. The MIP exhibited good sorption selectivity towards BPA, 4-tert-OP and 4-NP, and could be reused 5 times. Furthermore, a new method for ultrasensitive determination of BPA, 4-tert-OP and 4-NP in water by high performance liquid chromatography was developed, using MIP-based magnetic solid-phase extraction coupled with dispersive liquid-liquid microextraction. Under the optimum conditions, the limits of detection (LODs) for BPA, 4-tert-OP and 4-NP were 0.013, 0.010 and 0.010 μg L −1 , respectively. The proposed method was used to the detection of BPA, 4-tert-OP and 4-NP in real water samples, with spiked recoveries of 81.5–104.1% and relative standard deviations (RSDs) of 1.0–7.6%, indicating the multi-templates MIP could be a promising adsorbent for separation and analysis of alkylphenols.
研究领域:
环境科学
·
分析化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）