SENSORS AND ACTUATORS B-CHEMICAL
·
2013
·
IF 3.535
Zhenning Xu,Mo Wang,Tingting Zhou,Huanshun Yin,Shiyun Ai
In this article, we presented an electrochemical method for detection of DNA methylation and assay of DNA methyltransferase (MTase) activity using methylene blue (MB) as electrochemical indicator. After the DNA hybrid was methylated by T. aq I MTase, it could not be cleaved by Hinc II endonuclease. On the contrary, the double DNA without methylation could be cleaved, which would decrease the amount of intercalated MB. Thus, the DNA methylation status and MTase activity could be determinated based on the voltammetric signal change of MB. The methylation site could be found based on this method. The electrochemical signal of MB increased linearly with increasing T. aq I MTase concentration from 0.1 to 100 U/mL. Moreover, the inhibition investigation demonstrated that fisetin could inhibit the T. aq I MTase activity with the IC 50 value of 280 μM. Therefore, the screening of the inhibitors of MTase could be accomplished using the novel method.
研究领域:
生物化学
·
分子生物学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Bing Hao,Manyuan Gan,Jingjing Guo,Guoshen Li,Yanhui Song,Yongqing Shen,Bingshe Xu,Peizhi Liu,Junjie Guo
The rational design and fabrication of 2D heterojuctions are proven a promising strategy for boosting the performance of electrocatalysts. Although 2D platinum diselenide (PtSe 2 ) exhibits catalytic activity for hydrogen evolution reaction (HER), the catalytic performance is still unsatisfactory due to its inert basal plane, wide bandgap, and poor electron transfer ability. Herein, a new strategy is reported to construct PtSe 2 /PtCo heterojunctions by partial selenization of PtCo alloy for high-efficiency HER electrocatalyst, which exhibits a low overpotential of 38 mV at the current density of 10 mA cm −2 , a small Tafel slope of 22 mV dec −1 , and a superior stability over 24 h and 1000 cycles. The outstanding HER activity of the catalyst arises from the strong electronic interactions between PtSe 2 and PtCo in the heterojunctions, which induce electron transferring from PtSe 2 to PtCo and the d-band center down shifting, and thus optimize the H * adsorption/desorption. This work provides a novel strategy for constructing highly efficient heterostructure electrocatalysts, which facilitates the applications of hydrogen energy conversion.
研究领域:
材料科学
·
电化学
·
催化
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2024
·
IF 11.2
Jianxi Liu,Yifan Fang,Yang Ou,Xiaowei Shi,Yaoming Zhang,Qiang Chen,Lei Li,Feng Zhou,Weimin Liu
The synergy between corrosion protection and wear resistance is an effective strategy for the development of multifunctional coating to withstand complex working conditions. This study reports an epoxy resin coating filled with benzotriazole loaded metal-organic frameworks (BTA-MOFs) functionalized graphene oxide nanoribbons (GONR) that exhibit active anti-corrosion, act as a barrier to corrosive ion, and enhance wear resistance. The GONR@BTA-MOFs composite is synthesized through chemically etching multi-walled carbon nanotubes and subsequent electrostatic self-assembly corrosion inhibitors loaded MOFs onto the GONR. The composite demonstrates improved compatibility with epoxy resins compared to carbon nanotubes. The anti-corrosion performance of the composite coating is investigated using electrochemical impedance spectroscopy. After immersing in a 3.5 wt.% NaCl solution for 25 d, the alternating current impedance of the composite coating is three orders of magnitude higher than that of pure epoxy resin. Simultaneously, the controlled release of the corrosion inhibitor retards the deterioration of the coating after localized damage occurrence, which functions as active corrosion protection. The GONR@BTA-MOFs/EP composite coating exhibits the highest corrosion potential of -0.188 V and the lowest corrosion current of 3.162 × 10 −9 A cm −2 ) in the Tafel test. Tribological studies reveal a reduction in the friction coefficient from 0.62 to 0.08 after incorporating GONR@BTA-MOFs in the coating, with the wear volume being seven times lower than that of pure epoxy resin. The excellent lubrication effect of the nanomaterials reduces the coefficient of friction of the coating, thereby improving the abrasion resistance of the coating. The synergy between the self-lubrication of the two-dimensional layered fillers and the corrosion resistance of the smart inhibitor containers suggests a promising strategy for enhancing the performance of epoxy resins under complex working conditions.
研究领域:
材料科学
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腐蚀科学
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表面工程
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纳米技术
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Long Xie,Yaoyong Dong,Hui Ling,Zhenhua Xiang,Bei Long,Jingwei Wang,Lei Zhao,Xiao Zhou,Wenyuan He,Xuejun Zheng
Herein, we report the rational balancing of hydrogen adsorption/desorption dynamics by employing a synergistic Co and V dual-doping strategy to enhance the hydrogen evolution reaction (HER) performance of MoS 2 . The Co and V dual-doping MoS 2 (Co, V-MoS 2 ) was successfully synthesized in situ on carbon cloth (CC) substrates via a one-pot hydrothermal route, and the XRD, Raman, TEM, XPS, EDS and ICP characterizations validate the substitutional doping of Co and V into the MoS 2 lattice. The optimized Co, V-MoS 2 /CC exhibits significantly enhanced HER performance, requiring only 220.0 mV overpotential to reach −100 mA/cm 2 with a 61.9 mV/dec Tafel slope, surpassing both the Co/V mono-doped MoS 2 /CC and undoped MoS 2 /CC. Moreover, the polarization curve of Co, V-MoS 2 /CC exhibits a negligible potential decay of 8.4 mV at 50 mA/cm 2 after 3000 repeated cyclic voltammogram cycles, demonstrating superior durability. DFT calculations reveal that synergistic Co and V dual-doping in MoS 2 can balance the hydrogen adsorption/desorption kinetics at S sites near dopants, thereby optimizing the hydrogen adsorption free energy and accelerating the charge transfer, thus achieving far super HER performance. Our balancing hydrogen adsorption/desorption strategy enabled by Co, V dual-doping provides a promising avenue for improving the HER performance of TMDs-based electrocatalysts.
研究领域:
材料科学
·
电化学
·
催化
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能量存储与转换
·
纳米材料
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产品关联
DOI
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 10
·889
·
IF 4.4
Zhihao Cheng,Xin Han,Liying Han,Jinfeng Zhang,Jie Liu,Zhong Wu,Cheng Zhong
The exploration of catalysts for the oxygen evolution reaction (OER) with high activity and acceptable price is essential for water splitting to hydrogen generation. High-entropy materials (HEMs) have aroused increasing interest in the field of electrocatalysis due to their unusual physicochemical properties. In this work, we reported a novel FeCoNiMoZn-OH high entropy hydroxide (HEH)/nickel foam (NF) synthesized by a facile pulsed electrochemical deposition method at room temperature. The FeCoNiMoZn-OH HEH displays a 3D porous nanosheet morphology and polycrystalline structure, which exhibits extraordinary OER activity in alkaline media, including much lower overpotential (248 mV at 10 mA cm−2) and Tafel slope (30 mV dec−1). Furthermore, FeCoNiMoZn-OH HEH demonstrates excellent OER catalytic stability. The enhanced catalytic performance of the FeCoNiMoZn-OH HEH primarily contributed to the porous morphology and the positive synergistic effect between Mo and Zn. This work provides a novel insight into the design of HEMs in catalytic application.
研究领域:
材料科学
·
电化学
·
催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Virulence
·
2024
·
IF 5.5
Xin Wang,Feiyang Pu,Xuanye Yang,Xili Feng,Jiayou Zhang,Kai Duan,Xuanxuan Nian,Zhongren Ma,Xiao-Xia Ma,Xiao-Ming Yang
Influenza A virus (IAV) poses threat to patients receiving immunosuppressive medications since they are more susceptible to infection with severe symptoms, and even death. Understanding the direct effects of immunosuppressants on IAV infection is critical for optimizing immunosuppression in these patients who are infected or at risk of influenza virus infection. We profiled the effects of ten immunosuppressants, explored the antiviral mechanisms of immunosuppressants and demonstrated the combination effects of immunosuppressants with the antiviral drug oseltamivir in IAV-infected cell models. We found that mycophenolic acid (MPA) strongly inhibited viral RNA replication via depleting cellular guanosine pool. Treatment with 6-Thioguanine (6-TG) promoted viral protein degradation through proteasomal pathway. Filgotinib blocked mRNA splicing of matrix protein 2, resulting in decreased viral particle assembly. Furthermore, combined treatment with immunosuppressants and oseltamivir inhibited IAV viral particle production in an additive or synergic manner. Our results suggest that MPA, 6-TG and filgotinib could be the preferential choices for patients who must take immunosuppressants but at risk of influenza virus infection.
研究领域:
药理学
·
病毒学
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免疫学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE CHEMICAL LETTERS
·
2019
·
IF 3.839
Tong Guo,Lina Wang,Sen Sun,Yan Wang,Xiaoling Chen,Kangning Zhang,Dongxia Zhang,Zhonghua Xue,Xibin Zhou
A novel three-dimensional (3D) layered MoS 2 @graphene functionalized with nitrogen-doped graphene quantum dots (MoS 2 @N-GQDs-GR) composites as an enhanced electrochemical hydrogen evolution catalyst. The few layered MoS 2 nanoflowers supported on N-GQDs-GR surface were elaborately fabricated by one-pot hydrothermal method, which MoS 2 and N-GQDs-GR exist in a bonding manner of Mo-N. In addition, due to the layered MoS 2 sheet edge exposes more hydrogen evolution active sites and N-GQDs-GR have high conductivity, the composites exhibit prominent electrocatalytic activity with a low overpotential 99 mV, a small Tafel slope 49.3 mV/dec. Therefore, that the current work will develop HER catalysts may replace Pt.
研究领域:
材料科学
·
电化学
·
催化
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2018
·
IF 4.229
Xiaoling Chen,Kangning Zhang,Zhenzhen An,Lina Wang,Yan Wang,Sen Sun,Tong Guo,Dongxia Zhang,Zhonghua Xue,Xibin Zhou,Xiaoquan Lu
A novel three-dimensional (3D) hybrid consisting of molybdenum disulfide nanosheets (MoS 2 ) uniformly bound at N-doped macro-mesoporous carbon (N-MMC) surface was fabricated by the solvothermal method . The resulting MoS 2 /N-MMC hybrid possesses few-layer MoS 2 nanosheets structure with abundant edges of MoS 2 exposed as active sites for hydrogen evolution reaction (HER), in sharp contrast to large aggregated MoS 2 nanoflowers without N-MMC. The high electric conductivity of N-MMC and an abundance of exposed edges on the MoS 2 nanosheets make the hybrid excellent electrocatalytic performance with a low onset potential of 98 mV, a small Tafel slope of 52 mV/decade, and a current density of 10 mA cm −2 at the overpotential of 150 mV. Moreover, the MoS 2 /N-MMC hybrid exhibits outstanding electrochemical stability and structural integrity owing to the strong bonding between MoS 2 nanosheets and N-MMC.
研究领域:
材料科学
·
电化学
·
催化
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2024
·
IF 10.7
Haoxuan Li,Jinghui Wang,Mei Cui,Renliang Huang,Wei Qi,Rongxin Su
Ga based liquid metal is an ideal matrix to dissolve and disperse other metal atoms for catalysis. Seawater electrolysis is a promising alternative technology for hydrogen production in the crisis of freshwater resources. Here, we prepared dynamic Co, Pt dual-atom synergetic catalysis by dispersing Co, Pt atoms in Ga based liquid metal (denoted as Ga-CoPt). Liquid Ga boosts the dispersion, mobility and synergy of Co and Pt atoms and leads to dramatic increasement of catalytic performance for direct seawater electroreduction. Specifically, compared with solid state, the liquid Ga-CoPt shows much higher activity and stability of hydrogen evolution reaction at 100 mA cm-2 for 169 h in natural seawater, with lower overpotential (249 mV at 10 mA cm-2) and Tafel slope (145 mV/dec). Because the atomically dispersed Co, Pt atoms in liquid Ga make more active sites present at the interface of Ga-CoPt under low content of Co (5 wt%) and Pt (1 wt%). The fluidity of liquid Ga and mobility of Co, Pt atoms enhance the replenishment and regeneration of active sites in liquid Ga-CoPt, which promote the catalytic activity and stability simultaneously. Besides, the synergy of Co, Pt dual-atom in liquid Ga is confirmed that Co atom is the active site of water splitting and partial generated H species are adsorbed by Pt atom forming H*. At the same time, the other generated H species are combined with adjacent H2O generating H3O+. Subsequently, the adsorbed H* reacts with H3O+ to generate H2 by the Heyrovsky step.
研究领域:
催化
·
电化学
·
材料科学
·
能源技术
✓ 已验证
DOI
高影响因子
IONICS
·
2024
·Vol. 30
·期 4
·2287-2298
·
IF 2.4
Lin Jie,Ding Yihong,Jin Huile,Zeng Tianbiao
The development of inexpensive, highly effective and durable electrocatalysts for hydrogen production via water electrolysis is of paramount importance. Transition metal oxides, owing to their simplicity in preparation and cost-effectiveness, have been widely investigated, particularly cobalt, nickel, and manganese oxides. Inspired by the synergies of the ternary cathode materials of lithium-ion batteries (LiNi x Mn y Co 1- x - y O 2 , NMC), a simple and feasible method was used to prepare a graphite plate as the support, and Ni and Mn were co-doped with Co 3 O 4 as an efficient water decomposition catalyst. Experimental studies indicated that the 10% Ni and 10% Mn co-doped Co 3 O 4 (Co 2.4 Ni 0.3 Mn 0.3 O 4 , CNM-811) exhibited the lowest overpotential in the oxygen evolution reaction (OER), with CNM-811 achieving an overpotential of 338 mV at 30 mA cm −2 in NaOH aqueous solution, the Tafel slope is 79.71 mV dec −1 . In the hydrogen evolution reaction (HER), an overpotential of 190 mV was attained at 10 mA cm −2 . In overall water splitting, a cell voltage of 2.048 V was achieved at 100 mA cm −2 , which was superior to many analogous catalysts reported today.
研究领域:
材料科学
·
电化学
·
能量转换
·
催化
·
可再生能源
✓ 已验证
DOI
高影响因子
WATER AIR AND SOIL POLLUTION
·
2013
·Vol. 224
·期 7
·1-10
·
IF 1.748
Liu Fahui,Wang Chuanhua,Liu Xiaoyan,Liang Xia,Wang Qian
This research evaluated the effects of alkyl polyglucoside (APG), an environment-friendly surfactant, on the removal of anthracene (ANT), phenanthrene (PHE), and pyrene (PYR) from the soil cultivated with Scirpus triqueter , an aquatic native pioneer plant in the Yangtze estuarine wetland, China. Soils spiked with about 200 mg kg −1 of ANT, PHE, and PYR were individually irrigated with 0, 10, 20, 30, 40, 50, 100, and 150 mg L −1 of APG. Plant biomass yields, polycyclic aromatic hydrocarbons (PAHs) removal rates, soil microbial, and soil enzyme activities were quantified after 90 days’ cultivation of Scirpus triqueter . Experiments demonstrated that APG has an ability to facilitate PAHs degradation at appropriate concentrations. The highest removal rate of the PAHs was observed in 40 mg L −1 APG treatment, and the removal rates increased 23, 54, and 52 %, respectively, compared to the non-amended control pots. However, the PAHs removal rate decreased to a certain extent when high concentrations of APG were added. The effect on PAHs removal in the soil could be explained by the changed levels of plant biomass, soil microbial populations, and soil enzymatic activity affected by the APG. The results suggested that the use of Scirpus triqueter combined with APG was an effective means for the phytoremediation of the PAH-contaminated soil. At the same time, APG’s optimal concentration should be determined before the application in the PAH-contaminated wetlands.
研究领域:
环境科学
·
植物修复
·
土壤学
·
湿地生态学
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产品关联
DOI
高影响因子
Energy Storage Materials
·
2024
·
IF 18.9
Dengxu Wu,Jian Peng,Zhiwen Jiang,Lei Zhu,Yujing Wu,Chang Xu,Zhixuan Wang,Ming Yang,Hong Li,Liquan Chen,Fan Wu
Lithium-metal batteries with solid electrolytes (SEs) have emerged as promising electrochemical energy storage devices due to high energy density and safety. However , inherent challenges of deleterious lithium dendrite growth and poor interfacial stability hinder their practical application. Herein , a new type of room-temperature liquidous Li metal arene complex—Li-Phenanthrene (Phen)-Ether is explored to enable a 3D LiSi@Li-Phen-Ether (3D LSLL) anode with low cost, high safety and high ion/electron-conductivity. Symmetric cells with sulfide SE and 3D LSLL anode deliver an ultra-high critical current density (> 13 mA cm −2 ) and long cycle life (> 1000 h, 0.25 mA cm −2 ). Moreover, full battery (LFP/sulfide SE/3D LSLL) can operate at low-external pressure (0.5 MPa) and ambient temperature by introducing a flexible cathode/sulfide interlayer with high ion conductivity (2 mS cm −1 ). This unprecedented battery configuration demonstrates high-rate (2C) performance and long cycle life (over 300 cycles), which exceeds preciously-reported sulfide SE/lithium batteries at low stack pressures, and may open up a promising route for high-energy-density, cost-effective and safe rechargeable lithium batteries.
研究领域:
能量存储
·
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）