ENVIRONMENTAL RESEARCH
·
2026
·
IF 8.2
Tong Wang,Xinyuan Wang,Xiao Wei,Mengwei Yan,Sihang Gao,Wenjuan Yang
Efficient sequestration of oxytetracycline (OTC) from aqueous environments is limited by the single interaction force of conventional adsorbents, stemming fundamentally from the insufficient understanding and translation of adsorption mechanisms into rational material design. In this study, based on the molecular structure complexity of OTC, a new type of waste-derived macroscopic adsorbent with high adsorption capacity was developed from the perspective of multi-site and multiple intermolecular forces synergy design. A covalent organic frameworks (COFs) rich in secondary amine, ketone, and sulfonic acid groups was grown in situ on peony pod-based cellulose-sodium alginate composite aerogel (PCSA). The composite PCSA@COFs showed an effective OTC adsorption capacity of 43.44 mg/g at 298 K, following pseudo-second-order and Langmuir models, indicating spontaneous, endothermic chemisorption. Density functional theory calculations further revealed a strong binding energy of −55.11 kcal/mol between COFs and OTC with multiple interaction sites. Topological analysis via Atoms in Molecules theory demonstrated a multi-site three-dimensional synergistic mechanism through the identification of ring critical points and cage critical points, while the topological parameters revealed a partially covalent character in the interaction between sulfonic acid groups and OTC. This work provides a novel design concept for developing effective and eco-friendly adsorbents for antibiotic removal from aqueous environments.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Qinzhi Wang,Yijian Zhao,Zhan Shi,Xinyu Sun,Tong Bu,Changqiu Zhang,Zexiang Mao,Xiaohan Li,Li Wang
Azo dyes in soft drinks present a serious risk to human health and are strictly limited in many countries. Herein, we demonstrate that covalent-organic framework (COF) can be facilely grown on magnetic metal–organic framework (MOF) to form three kinds of porous Fe 3 O 4 @MOF(M = Fe, Ti, Zr)@COFs composites for efficient azo dyes adsorption. Adsorption performances of Fe 3 O 4 @MOF(M = Fe, Ti, Zr)@COFs toward azo dyes were systemically investigated by adsorption kinetics , adsorption isotherms and adsorption thermodynamics. Under optimized conditions, the maximum adsorption capacities of both Fe 3 O 4 @MOF(Fe)@COF and Fe 3 O 4 @MOF(Zr)@COF for Congo red (CR) are 1250.02 and 625.13 mg g −1 , and the Fe 3 O 4 @MOF(Ti)@COF for Chrysoidine (CYD) is 294.12 mg g −1 , all which are higher than those of mostly previous reports. Furthermore, possible mechanisms of adsorption were revealed through Fourier-transform infrared spectra and X-ray photoelectron spectroscopy analysis. These Fe 3 O 4 @MOF(M = Fe, Ti, Zr)@COFs composites also present good biocompatibility, and exhibit high adsorption capacities for CR or CYD in soft drinks, which can be suggested as effective adsorbents for the azo dyes removal from soft drinks.
研究领域:
环境科学
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材料科学
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化学工程
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
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IF 8.128
Chunfeng Mao,Kai Yin,Chenghan Yang,Guomeng Dong,Guokai Tian,Yiwei Zhang,Yuming Zhou
Controlling the spatial confinement effect and highly dispersed Pd nanoparticles (NPs) can help to improve applicability in catalysis, energy conversion, and separation. However, the nonspatial confinement effect, agglomeration of Pd NPs of catalyst and harsh reaction conditions have become the urgent problems to be solved in Suzuki-Miyaura cross-coupling reaction. Herein, we report the first application of a new MOFs@COFs by using core with metal organic frameworks (MOFs) NH 2 -MIL-101(Fe) and shell with covalent organic frameworks (COFs) for loading Pd NPs. The quickly formation of a transition state, the highly dispersed Pd NPs and the advancedly spatial confinement effect were achieved by coupling Fe base synergistic active components, electron-oriented anchoring with controlling pore scale, respectively. Most notably, as a proof-of-concept application, the high catalytic activity of NH 2 -MIL-101(Fe)@Pd@COFs( 3 + 3 ) in catalysis is elucidated for Suzuki-Miyaura coupling reaction by the broad scope of the reactants and the preeminent yields of the products, together with excellent stability and recoverability. With this strategy, the mechanism of Suzuki-Miyaura coupling reaction was verified by examining the catalytic activity. We hope that our approach can further facilitate the study of the design and use of functional MOFs@Pd@COFs materials.
研究领域:
材料科学
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催化化学
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PubMed
高影响因子
Membranes
·
2025
·Vol. 15
·期 10
·316
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IF 3.6
Yuan Zhai,Zimeng Zheng,Xinhao Cui,Kun Jiang,Ao Sheng,Heyun Wang
In this study, hydrophilic covalent organic framework (COF) nanosheets with triazine structures and hydrophobic COF nanosheets with fluorinated imine skeletons were designed to enhance the membrane separation process for ethanol pervaporation. The mass transfer of ethanol–water mixtures within the confined structures of COF nanosheets was investigated through experimental characterization and computational simulations, establishing a quantitative relationship between mass transfer performance and the pore size/chemical properties of COF nanosheets. These COF nanosheets were employed to optimize the confined architecture of mixed matrix membranes (MMMs), effectively regulating the critical parameters of MMMs and improving their separation performance. Through systematic investigation of formation mechanisms and modulation principles, we revealed the correlation between confined structural parameters and membrane separation efficiency. This work develops methodologies and foundational theories to overcome the permeability-selectivity trade-off effect, providing theoretical guidance for designing novel membrane materials with ethanol-permelective COF-based MMMs.
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高影响因子
ACS Applied Materials & Interfaces
·
2026
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IF 7.8
Xu Ningning,Zhang Yi,Liu Yu,Zheng Yan,Zhao Shuang,Chen Liang,Yuan Jintao,Shi Jiahua,Yu Shuling
Diabetic wounds remain a global health challenge due to vascular insufficiency, bacterial infection, and persistent inflammation. Herein, we designed and prepared a triple-synergistic nanoenzyme platform with antibacterial, anti-inflammatory, and angiogenesis-promoting effects, which was formed by coloading a porphyrin covalent organic framework (Por-COF) with glucose oxidase (GOx) and manganese carbonyl (MnCO). Under near-infrared irradiation, Por-COFs produce a large number of reactive oxygen species (ROS) and localized hyperthermia. Simultaneously, GOx consumes the glucose in wounds to produce gluconic acid and H 2 O 2 , which trigger the decomposition of MnCO into immunomodulatory carbon monoxide (CO) and catalytically active Mn 2+ / 3+ ions. The released Mn 2+ / 3+ ions catalyze H 2 O 2 to produce highly toxic •OH through peroxidase-like activity, enhancing bacterial elimination, while the produced CO improves M1-to-M2 macrophage polarization to resolve inflammation and suppresses heat-shock proteins to enhance PTT efficacy. This prepared nanoplatform (Por-COF@GOx/MnCO) achieved more than 99.99% antibacterial efficiency against Escherichia coli , Staphylococcus aureus , and methicillin-resistant Staphylococcus aureus and accelerated wound healing by promoting angiogenesis, ROS scavenging, and immunomodulation. The designed triple-synergistic nanoplatform—integrating glucose oxidase cascading MnCO-based peroxidase-like activity, phototherapy, and CO immunomodulation—shows great potential as a therapeutic strategy for diabetic wound repair.
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高影响因子
Analytical Methods
·
2021
·Vol. 13
·期 38
·4503-4514
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IF 2.896
Yasan He,Xiaogeng Lin,Yuan Tang,Ling Ye
In this study, an electrochemical sensing strategy was developed based on the synergies of gold nanoparticles (AuNPs) doped carboxylated covalent organic frameworks (ACOFs) and poly(fuchsin basic) film for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). This strategy not only took advantage of the adopted materials but also made use of the H-bonding and electrostatic interaction between the three compounds and materials. For this sensing, a poly-BFu film was formed on the surface of bare glass carbon electrode (GCE) under a constant potential. AuNPs was highly dispersed and immobilized on the constructed ACOF-TaTp to obtain AuNPs@ACOF. The constructed sensor AuNPs@ACOF/p-BFu/GCE combined the merits of high surface area, hydrophilicity, conductivity, and selective affinity, consequently exhibiting high sensitivity and selectivity toward the simultaneous detection of AA, DA, and UA with wide linear response ranges of 25–1500 μM, 0.75–40 μM, and 1–200 μM, respectively. The corresponding detection limits were 12.0 μM, 0.15 μM, and 0.22 μM. The simultaneous determination of UA in real human urine sample further confirmed the practicability of the designed electrode.
研究领域:
分析化学
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生物医学工程
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材料科学
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高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2021
·
IF 4.759
Rujia Shen,Lijin Huang,Ruiqi Liu,Qin Shuai
In this work, hierarchical porous covalent organic frameworks (HP-COFs) foam, named as HP-TpBD, was prepared by using 1,3,5-trimethylphloroglucinol (Tp) and benzidine (BD) as building blocks under the assistant of NaCl template. Its potential application as the sorbent for solid phase extraction (SPE) of sulfonamides (SAs) in meat products were explored by coupling with high performance liquid chromatography-mass spectrum (HPLC-MS) analysis. The key factors affecting extraction efficiency were well studied. Under the optimum conditions, the proposed method exhibited high preconcentration factors of 100, low limit of detection (0.10-0.23 μg/kg), and wide linear ranges (0.5-200 μg/kg). In addition, the determination of SAs in real samples were realized with satisfactory recoveries (82.8-119.9%), demonstrating the applicability of the proposed method. The easy operation, superior extraction affinity and good recycle performance demonstrated the resulting HP-COF foam is a promising adsorbent for the preconcentration of trace organic compounds from complex matrix.
研究领域:
分析化学
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食品科学
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材料科学
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Zi-Wen Zhou,Chun-Xiu Liu,Chun-Xian Cai,Na Wang,Xiao-Qi Yu
In this work, PEG modified photocatalytic covalent organic framework (PEG@CTF-OMe) was co-immobilized with laccase into Cu doping calcium alginate gel beads (Ca/Cu-PEG@CTF-OMe-lac). PEG@CTF-OMe improved the light stability of laccase under blue light irradiation , and external introduction of copper into gel beads stabilized the conformation and improved pH adaptability of laccase. With the help of 2,2-binamine-di-3-ethylbenzothiazolin-6-sulfonic acid (ABTs), the immobilized laccase (Ca/Cu-PEG@CTF-OMe-lac) presented outstanding synergistic removal of pollutants by photocatalysis and enzymatic catalysis, as well as ABTs radicals generation promoting by copper ions in the laccase-mediator system. The removal recyclability performance assay found that the Ca/Cu-PEG@CTF-OMe-lac gel beads had more than 80 % removal efficiency for phenol , 4-chlorophenol, 2,4-dichlorophenol, nonyl phenol, bisphenol A and indole in water at 25 °C after 5 cycles, when the concentration reached as high as 70 mg/L, 60 mg/L, 120 mg/L, 100 mg/L, 100 mg/L and 100 mg/L, respectively. The high synergistic removal performance obtained by the gel beads co-immobilizing laccase and photocatalytic CTFs showed greater practical application value.
研究领域:
环境科学
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生物技术
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材料科学
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高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-10
·
IF 15.7
Chen Yong-Jun,Xu Yi-Ming,Ye Xiao-Liang,Luo Zhi-Peng,Zhu Shi-Peng,Li Ke-Feng,Lu Jiang-Feng,Wang Guan-E,Xu Gang
To significantly enhance reaction efficiency of porous heterojunctions in various applications, precise engineering of customization heterostructures through energy-level modulation is indispensable. Herein, the preparation of a core-shell porous heterojunction, UiO-66@TDCOF, is reported. Taking advantage of adjustable structure of metal-organic frameworks (MOFs), the energy-level of UiO-66 core is tailored to precisely align with that of porphyrin-based covalent organic framework (denoted as TDCOF) shell. As a results, the heterojunction transitions flexibly from a type-I to a type-II configuration, which remarkably enhances the efficiency of charge separation under light irradiation, resulting in exceptional performances in chemiresistive gas sensing. Notably, the sensitivity of (NH 2 ) 1.24 -UiO-66@TDCOF towards NO 2 is at a high level among all reported heterojunctions under visible-light condition, surpassing the majority of previously reported MOF and COF materials. This research not only presents a strategy for the design of heterojunctions but also gives an approach to material design tailored for chemical applications.
研究领域:
材料科学
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纳米技术
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气体传感技术
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异质结工程
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光化学
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化学传感器
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PubMed
高影响因子
Advanced Energy Materials
·
2025
·
IF 26
Chenlong Zhang,Jialong Duan,Renni Luan,Ya Liu,Jingwei Zhu,Jie Dou,Yueji Liu,Qiyao Guo,Tianyi Liu,Xinyu Zhang,Linzheng Ma,Benlin He,Yuanyuan Zhao,Chongwen Li,Qingzhong Xue,Qunwei Tang
Achieving high-quality perovskite (ABX 3 ) film is the key to the improvement of efficiency and stability of perovskite solar cells (PSCs) for subsequent commercialization, yet traditional crystallization relying on the quick reaction between AX and BX 2 components often involves photoinactive intermediate phases and imperfections that go against the device performance. Herein, we report a new strategy for retarding perovskite crystallization and defect passivation by customizing the non-skeletal groups (such as -F, -H, -OC 2 H 5 and etc.) in covalent organic frameworks (COFs). Given the discernable charge transfer feature depending on donor-acceptor interaction strength, theoretical and experimental results demonstrate that, compared to the electron-donating group, the electron-withdrawing -F atoms induce local asymmetric electron distribution, forming a negative Lewis-base center at acceptor unit, a positive π-acidic center at donor unit, and a hydrogen bond center at side chain to discretely interact with PbI 2 , free I − anions and organic cations (formamidinium, FA + ). As a result, the F-functionalized-COFs enable micro-spatial all-components-delocalized crystallization and defect passivation, thus promoting the efficiency of inverted PSC up to 26.02%, along with the significantly improved stability after aging under 75°C for 1000 h, 10% relative humidity for 2000 h, and continuous illumination over 1100 h.
研究领域:
材料科学
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光伏技术
·
有机-无机杂化材料
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纳米材料
·
能源材料
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Zhihao Wang,Qiuli Cheng,Xingda Jiang,Xinyang Chu,Bingcan Li,Leitao Zhang,Wenlan Wu,Junbo Li,Ravin Narain
Nanoparticles-based drug delivery systems show great promise for cancer therapy due to the advantages of crossing physiological barrier, high drug availability and good stability. However, deep tumor penetration, long blood circulation, and rapid drug release remain intractable problems for nanocarriers. In this work, we report a tumor microenvironment-sensitive nanodrug delivery system containing both acidic pH and hypoxia response sites to achieve enhanced drug permeability and on-demand release for precise cancer therapy. The covalent organic frameworks (COFs) with introduced azobenzene (azo) groups were used as employed as nanocarrier, and modified by pH-sensitive sulfamide-based zwitterionic polymers (PBA), followed by loading with the chemotherapeutic drug doxorubicin (DOX) to obtain COF-PBA@DOX. Copolymer PBA achieved charge conversions in tumor acidic environment, resulting in a positive charge on the nanocarrier surfaces, thus facilitating the augmented tumor accumulation. Meanwhile, azo which was formed the COF carrier, could be reduced to amines by the highly expressed azoreductase under tumor hypoxia conditions, resulting in nanoparticle dissociation and the drug-controlled release at the solid tumor sites. The fabricated dual-responsive nanomedicine, based on the surface charge-reversal of zwitterion in the acidic environment of tumor, can realize the accumulation and targeted drug release at the tumor site, which has great potential as a nanocarrier in tumor therapy.
研究领域:
纳米技术
·
癌症研究
·
药物递送系统
·
材料科学
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Shijian Zhou,Yuexin Shi,Guangyuan Chen,Weiguo Kong,Hao Hu,Haoran Xie,Changlai Li,Jinping Qin,Zewu Zhang,Luming Peng,Xiaokang Ke,Yan Kong
Structural design is important and challenging for the fabrication of covalent organic frameworks (COFs) in the photocatalytic applications. Hydroxyl groups have been found to be the active sites for O 2 adsorption and promote the electron-donating conjugation effects, which favorable for the oxygen reduction reaction (ORR) in photocatalytic hydrogen peroxide (H 2 O 2 ) evolution. This study reports the preparation of “fragmentized” COFs (T x H y -COFs) photocatalysts and their application in H 2 O 2 synthesis, as well as the direct hydroxylation of benzene to phenol. The results demonstrate that the functional design of surface hydroxyl (–OH) modification on fragmentized T x H y -COFs was achieved by varying the feed ratio of TAPT and THTA monomers, which greatly enhances surface hydrophilicity and effectively improves the separation and transfer of photoexcited electrons and holes. Under visible light irradiation without sacrificial agents, the fragmentized T 1 H 1.8 -COF exhibits a boosting H 2 O 2 yield of 2567 μmol g −1 h −1 , which is 4.2 times higher than the original T 1 H 1 -COF. Furthermore, the introduction of metal ions (Fe 3+ etc.) into the COF framework through the impregnation method enables the in situ activation of H 2 O 2 , allowing the direct hydroxylation of benzene to phenol in aqueous systems, with yield of 9.4 % and selectivity of 99 %. The results of this work demonstrate that the prepared photocatalyst exhibits high stability and photocatalytic activity by structural design optimization, showing great potential for industrial applications in H 2 O 2 production and direct photo-oxidation.
研究领域:
材料科学
·
环境科学
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高影响因子
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