JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
·
2023
·
IF 3.1
Yu Hongrui,Huang Xueying,Zhou Liping,Wang Yi
Active packaging with antimicrobial functions to improve the quality and extend the shelf life of food products has gained great interest. Because commercial plastic packaging materials are not biodegradable and cause great environmental problems, plant-derived natural materials have been widely studied for the application of biodegradable packaging materials. Herein, we reported a study of essential oils (EOs)-loaded zein film. Cinnamaldehyde (CIN), carvacrol, and eugenol were added to equip the films with antimicrobial effects, while polyethylene glycol (PEG) and oleic acid (OA) were selected for the improvements of mechanical properties. The results showed that PEG efficiently improves the tensile strength and elongation (%E) of zein films compared to OA, although PEG induced weaker water barrier properties of the films than OA. FTIR spectra confirmed the formation of the hydrogen bonds between zein and PEG/OA. The EO-embedded zein film showed better antimicrobial effects than EO themselves. CIN-embedded films showed the highest antimicrobial effect among the three EOs. The sizes of the inhibition zones against Staphylococcus aureus of PEG-added zein films with 1%, 3%, and 5% CIN were 5.67, 12.67, and 16.67 mm, which were larger than that of pure CIN, with the sizes of 0.00, 3.00, and 4.67 mm, respectively. The developed films demonstrate a gradual release of EOs and show antimicrobial effects up to 96 h, indicating their high potential for the applications as active food packaging.
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高影响因子
MEAT SCIENCE
·
2023
·
IF 7.1
Zhen Zeng,Yu-Jing Yang,Qian Tu,Yu-Ying Jian,Da-Ming Xie,Ting Bai,Shan-Shan Li,Yun-Tao Liu,Cheng Li,Cai-Xia Wang,Ai-Ping Liu
To solve the problem of easy spoilage of chilled meat during storage, we fabricated a novel composite film using carboxymethyl chitosan (CMCS)/pullulan (Pul)/eugenol (E) by casting method. The results showed that the mechanical properties of the films were better when the CMCS/Pul ratio was 2.5/2.5. The Fourier transform infrared spectroscopy (FTIR) results showed that intermolecular hydrogen bonds were formed among E, CMCS, and Pul, which was consistent with the rheological test results. Scanning electron microscopic (SEM) images showed that eugenol was well dispersed in the CMCS/Pul matrix. The addition of eugenol significantly increased the antibacterial properties and antioxidant properties. Moreover, when 5% eugenol was added, the water vapor permeability (WVP) of the film reduced to 2.41 × 10 −11 g/m·s·Pa. Finally, the freshness of the chilled meat wrapped with the eugenol-containing composite film was prolonged, thereby offering a potential alternative to synthetic materials.
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高影响因子
ELECTROCHIMICA ACTA
·
2014
·
IF 4.086
Xiaoyun Lin,Yongnian Ni,Serge Kokot
A simple one-step electrodeposition method was used to construct a glassy carbon electrode (GCE), which has been modified with Cu doped gold nanoparticles (GNPs), i.e. a Cu@AuNPs/GCE. This electrode was characterized with the use of scanning electron microscopy (SEM) and X-ray diffraction (XRD) techniques. The eugenol was electrocatalytically oxidized at the Cu@AuNPs/GCE. At this electrode, in comparison with the behavior at the GCE alone, the corresponding oxidation peak current was enhanced and the shift of the oxidation potentials to lower values was observed. Electrochemical behavior of eugenol at the Cu@AuNPs/GCE was investigated with the use of the cyclic voltammetry (CV) technique, and additionally, in order to confirm the electrochemical reaction mechanism for o-methoxy phenols, CVs for catechol, guaiacol and vanillin were investigated consecutively. Based on this work, an electrochemical reaction mechanism for o-methoxy phenols was suggested, and in addition, the above Cu@AuNPs/GCE was successfully employed for the analysis of eugenol in food samples.
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INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Luzhou Cai,Ling Li,Dong Li,Yanping Wu,Jinrong Bai,Kai Zhong,Hong Gao
The loss of grains in the production chain caused huge waste worldwide, and the control of plant pathogenic fungi during harvest time is a critical solution to mitigate the damage. Eugenol, an important component of clove oil ( Syzygium aromaticum L.), has antioxidant, antifungal, and other activities. In this study, the unstable eugenol was incorporated into the nanoscale γ-cyclodextrin metal-organic framework (γ-CD-MOF), a cubic porous structure synthesized by vapor diffusion method. The investigation of morphologies, functional groups, crystalline structures and weight losing behaviors demonstrated the inclusion complex prepared from γ-CD-MOF and eugenol (CMFE). Compared with the γ-CD loaded with eugenol (CE), CMFE exhibited an improved loading rate with 4.06 % ( w/w ). And CMFE enhanced the stability of its inner eugenol against degradation by light and air. Moreover, the CMFE demonstrated a significant anti -F. graminearum activity both in the medium and on the wheat grains. The inhibition rate reached 83.8 % at 8 mg/mL in vitro , while the growth of the hyphae was effectively restrained at 4 mg/g in vivo . CMFE could damage the mycelial cell wall and trigger intracellular reactive oxygen species (ROS) accumulation, thus exhibiting its anti- F. graminearum activity. Our results showed that the biocompatible CMFE would be an environment-friendly substitute to chemical fungicides for the prevention of fungal contamination caused by F. graminearum .
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ANALYTICAL SCIENCES
·
2024
·
IF 1.8
Sha Ou,Wu Yunfan,Dai Xincheng,Li Huiwen,Xu Yuan,Wang Ziwen,Zhang Pu
In this study, a reliable method for determining eugenol content in environmental water samples was established by combining magnetic solid-phase extraction with high-performance liquid chromatography. Magnetic molecular imprinted polymers MGO@MIPs were prepared through surface molecular imprinting technique with eugenol as the template molecule. The material displayed good superparamagnetic properties and magnetic responsiveness in favor of rapid separation. The adsorption properties of MGO@MIPs for eugenol were evaluated through adsorption kinetics and selectivity experiments. MGO@MIPs were found to have favorable reusability and obvious selectivity for eugenol. In addition, adsorption and elution conditions were investigated. Under optimal conditions, a linear relationship was obtained between the concentration of eugenol and its peak area in the range of 0.02–5 mg/L ( R 2 = 0.9998) and the limit of detection was 4.0 × 10 –6 mg/mL. The performance of the established method was assessed with the average recovery of 96.59–102.20% and the relative standard deviation (RSD) below 3.5%. The application of this method provides a new perspective for the separation, enrichment and detection of eugenol in water environment. Graphical abstract Preparation of the molecularly imprinted polymers
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Zheng Wang,Shuhong Nie,Enhui He,Guanglei Song,Xiaohui Jiang,Xia Li,Xuefeng Yan,Liangmin Yu
The practical application of low surface energy organosilicon in marine antifouling is significantly limited due to its poor ability to eliminate biofoulings. Herein, combining organosilicon with zinc acrylate resin containing eugenol group (EAM-Zn) by means of semi-interpenetrating polymer networks (SIPNs), an innovative self-cleaning and antifouling composite coating was developed (named E x Si y ), which integrates low surface energy and self-polishing. After 35 days of immersion in seawater, the hydrophobic organosilicon of E 1 Si 3 coating impedes the penetration of water molecules into the interior of the coating, resulting in the weight loss rate of EAM-Zn being reduced from 24.99 % to 1.92 %. The surface energy of the E x Si y coating after 7 days of immersion in seawater is decreased to 20 m J/m 2 , achieving self-cleaning under the action of flowing water shear. Antifouling performance tests show that the E 1 Si 1 coating increases the inhibition rate of the original silicone against Escherichia coli from 48.95 % to 77.5 %. The adhesion area of diatoms on the surface of the E x Si y coating is only 2 %, and the removal strength of pseudobarnacles is merely 0.2 MPa. Most significantly, the composite coating demonstrates a remarkable antifouling effect in the Yellow Sea waters of Qingdao. Overall, this research presents a preparation method for enhancing the antifouling performance of organosilicon antifouling coatings, promoting the development of multifunctional and environmentally-friendly marine antifouling coatings.
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BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
·
2025
·Vol. 137
·期 1
·e70058
·
IF 3.3
Mengtian Pan,Xiang Li,Xinjuan Tian,Lele Zixin Yang,Weirong Fang
Ischemic stroke (IS) is one of the most sinister diseases and the second leading cause of death in the world. Eugenol (EUG) is a natural and biologically active component that can be extracted from various plants. Studies have found that EUG can alleviate middle cerebral artery occlusion and reperfusion (MCAO/R) injury in mice, but the specific mechanism remains vague. Tripartite motif protein 59 (TRIM59) is a member of TRIM protein family, a group of E3 ubiquitin ligases. In this article, we conducted both in vivo and in vitro experiments to determine the effect of EUG on ischemia–reperfusion injury and to explore the underlying mechanisms by manipulating the expression of TRIM59. Results showed that EUG alleviates acute injury and promotes functional repair of mouse IS by enhancing the phagocytosis of microglia through up-regulating the TRIM59, activating the STAT3 pathway and promoting the expression of CD11b.
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FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Yunge Zhang,Mi Li,Yuanchang Cao,Jian Ju,Qingmin Chen,Yanli Ma,Cuicui Li
Novel biodegradable bilayer film with unidirectional release. • PLA/ZnO/MgO outer layer improves barrier and UV-blocking. • Inner gelatin/EUG-THY layer ensures long-term antimicrobial activity. Fresh cucumbers are highly perishable due to moisture loss, microbial infection, and oxidative deterioration. In this study, a biodegradable bilayer active packaging film with unidirectional release was developed for cucumber preservation. The outer PLA layer was reinforced with 2 wt% of a 1:1 ZnO/MgO nanoparticle mixture, exhibiting enhanced hydrophobicity, mechanical strength (tensile strength 62.75 MPa), reduced water vapor permeability (88.7 g/m 2 ·24 h), and excellent UV-blocking. The inner layer was prepared by electrospinning gelatin loaded with 0.2–0.4 wt% eugenol (EUG) and thymol (THY). Unidirectional release evaluation showed that >92% of EUG and THY were released toward the food simulant via a non-Fickian diffusion mechanism ( n = 0.54–0.57). The films exhibited concentration-dependent antimicrobial and antioxidant activities. During 21 days of storage at 4 °C, cucumbers packaged with the EUG/THY-loaded bilayer films showed significantly lower weight loss, reduced color deterioration, and enhanced antioxidant enzyme activities. The 0.4% EUG/THY formulation extended cucumber shelf life to 18–20 days. This bilayer design offers a promising strategy for eco-friendly active packaging with unidirectional release for fresh produce preservation. Download: Download high-res image (174KB) Download: Download full-size image
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Journal of Hazardous Materials Advances
·
2026
·
IF 9.1
Xin-Ru Zhang,Yue-Hua Chen,Gui-Zhong Xin,Cheng Qian,Mu Zhang,Xiao-Wei Zhang,Zi-Xuan Ding,Fang-Tong Liu,Hui Zhang,Rui-Bo Sun,Tian-Qi Zhang,Hong-Juan Hou,Kang Ting-Guo,Hui-Peng Song
The aquatic toxicity mechanism of methyl eugenol (ME), an emerging insect sex pheromone-based pesticide, remains unclear. To address this issue, we established a strategy termed "1N (network toxicology) + 2T (toxicity assessment, transcriptomics) + 3M (metabolomics, molecular docking, mechanism verification)" to systematically investigate its toxicity, focusing on ferroptosis as a potential core mechanism. Toxicity assessment determined the 96-hour LC₅₀ of ME in zebrafish to be 2.536 mg/L and it caused marked histopathological damage in liver and gill tissues. Furthermore, integrated transcriptomic and metabolomic analysis revealed the co-enrichment of dysregulated genes and altered metabolites in ferroptosis-related pathways. Subsequently, network toxicology identified CDK1, TP53, CHEK2, and CTNNB1 as key ferroptosis-related targets of ME, and molecular docking confirmed their stable binding via hydrogen bonds with lysine residues. For mechanism verification, the ferroptosis inhibitor ferrostatin-1 (Fer-1) significantly reduced ME-induced mortality, alleviated tissue damage, and mitigated oxidative stress and lipid peroxidation. These findings demonstrated that ferroptosis was the primary toxicity mechanism of ME in zebrafish. Our study provides scientific evidence for the ecological risk assessment of ME and presents the "1N+2T+3M" strategy as an applicable framework for evaluating other pesticides.
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高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2023
·
IF 6
Kejun Chen,Charles Brennan,Jianxin Cao,Guiguang Cheng,Lin Li,Yuyue Qin,Haiyan Chen
In this work, we prepared chitosan/eugenol-loaded IRMOF-3 nanoparticles (CS/IRMOF-3-EU) composite films using (0, 2, 4, and 6 wt%) isoreticular metal-organic framework (IRMOF-3) nanoparticles loaded with eugenol (IRMOF-3-EU), co-blended with chitosan to develop environmentally friendly food packaging materials with sustained antimicrobial activity. The microstructure and physicochemical properties of the composite films were investigated. The addition of IRMOF-3-EU to the CS matrix significantly enhanced the UV-blocking property and elongation at the break of the composite films; the CS/IRMOF-3-EU composite films inherited the antioxidant and antibacterial properties of eugenol (EU), and the DPPH radical scavenging ability was increased to 53.8% with the addition of 6% IRMOF-3-EU, while it showed excellent antibacterial ability; in addition, the CS/IRMOF-3-EU composite films achieved the sustainable release of eugenol to achieve the long-lasting antibacterial effect. Experiments on strawberry preservation applications showed that the CS/IRMOF-3-EU films slowed down the deterioration of strawberry quality, delayed the decline of hardness, effectively suppressed weight loss, H 2 O 2 content, and malondialdehyde content, and delayed the decline of catalase activity and peroxidase activity. It showed that the CS/IRMOF-3-EU composite films could be used to maintain the postharvest quality and prolong the shelf life of strawberries.
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RSC Advances
·
2016
·Vol. 6
·期 22
·17857-17866
·
IF 3.289
Jinyue Dai,Yanhua Jiang,Xiaoqing Liu,Jinggang Wang,Jin Zhu
Two kinds of UV-curable monomers (EM2G and EM3G) were synthesized from eugenol via a thiol–ene reaction. Their chemical structures were confirmed by FT-IR, 1H-NMR and 13C-NMR before they were employed to copolymerize with acrylated epoxidized soybean oil (AESO). Bio-based UV curable resins were prepared and their thermal and mechanical properties were investigated by tensile testing and dynamic mechanical analysis (DMA). Their coating properties on tinplate were also studied. The results showed that the tensile strength, tensile modulus and glass transition temperatures of the cured AESO were significantly improved after the introduction of eugenol-based monomers. In addition, the UV-cured resins could be well coated on the surface of tinplate and good coating properties, such as hardness, flexibility, adhesion, solvent resistance and water absorption were demonstrated.
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Food Bioscience
·
2024
·
IF 4.8
Yuyue Qin,Hongda Yu,Kejun Chen,Rui Cui,Jianxin Cao,Zhengxuan Wang,Zhi-Hong Zhang,Thanapop Soteyome
The market value of strawberries is considerably impacted by quality deterioration and senescence during postharvest storage. In the study, the effect of isoreticular metal-organic skeleton (IRMOF-3) nanoparticles loaded with eugenol/chitosan-based active packaging film on the metabolism of reactive oxygen species (ROS) and the change rule of the structure of the microbial community in strawberries inoculated with strawberries spoilage bacteria ( Botrytis cinerea ) during the storage period was investigated. The results demonstrated that composite film contribute to the sustenance of reduced hydrogen peroxide and superoxide anion concentrations and the suppression of malondialdehyde accumulation, in contrast to the control group. This investigation revealed that the composite film significantly bolstered the antioxidant enzyme activities and disease resistance-related enzyme activities of strawberries, encompassing polyphenol oxidase, peroxidase, superoxide dismutase (SOD), and catalase (CAT). Moreover, the transcription levels of SOD and CAT genes were notably elevated in strawberries packed within the composite films. Besides, the composite film had an inhibitory effect on pathogenic bacterial genera ( Ralstonia , Sphingomonas , and Erwinia ) and fungal genera ( Botrytis cinerea ) that cause strawberries spoilage and a delayed decline in bacterial genera (unidentified_ Chloroplast and Chryseobacterium ) and fungal genera ( Rhodotorula ) that are biocontrols of strawberries postharvest diseases. Therefore, this study provides novel perspectives on the mechanisms underlying the preservation of fruits and vegetables, focusing on alterations in ROS metabolism and microbiota composition during storage.
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危险品化学品经营许可证（带存储）