Small Methods
·
2026
·
IF 8.7
Rimsha Abbas,Muhammad Umair,Zhao Fu,Jingjing Luo,Suzhu Yu,Jun Wei
Omnidirectional strain sensors capable of detecting large and complex deformations are highly promising for wearable motion monitoring; however, achieving both multidirectional strain perception and enhanced electrical sensitivity remains challenging. Herein, a peelable circular piezoresistive strain sensor based on KH570-modified hydroxylated multi-walled carbon nanotubes (m-MWCNT-OH)/Ecoflex is developed through a screen-printing strategy and further functionalized with a copper (II) 2,3,6,7,10,11-hexahydroxytriphenylene (Cu 3 (HHTP) 2 ) conductive metal-organic framework (c-MOF)/poly(3,4-ethylenedioxythiophene) nanofiber (PEDOT-NFs) nanolaminate. The circular sensing architecture facilitates uniform strain distribution and orientation-independent strain transfer, while the c-MOF/PEDOT-NFs coating constructs additional conductive pathways, enhancing strain-induced resistance variation. The sensor is fabricated using a sequential process involving screen printing of the m-MWCNT-OH/Ecoflex sensing layer, peel transfer, and spray deposition of the functional coating. The resulting sensor demonstrates a wide strain detection range of 0%–300%, a gauge factor (GF) of 8, a fast response time of 33 ms, a recovery time of 420 ms, and stable performance over 10 000 loading-unloading cycles. Compared with unmodified sensor, c-MOF/PEDOT-NFs functionalization significantly improves electrical sensitivity while maintaining the intrinsic omnidirectional sensing capability. Finite element analysis (FEA) confirms similar strain-transfer characteristics under different loading directions. The sensor enables accurate monitoring of multidirectional human motions, highlighting its potential for wearable electronics, soft robotics, and human-machine interfaces.
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高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Silong Qiang,Mei Chen,Qin Zhou,Shikun Li,Jianjun Liao,Shiwei Lin
Hydroxyl-rich surface (BiO)₂OHCl/MWCNT enhances heavy metals accumulation via coordination. • Anion modulation (OH − /Cl − ) optimizes internal electronics for faster charge transfer. • Conductive MWCNT network further accelerates interfacial electron transfer. • LODs of 0.23 μg/L Pb 2+ and 0.41 μg/L Cd 2+ with 96–104% recovery in seawater samples. The escalating contamination of aquatic ecosystems by toxic heavy metal ions Cd 2+ and Pb 2+ necessitates reliable monitoring solutions. Herein, a glassy carbon electrode modified with a hydroxylated bismuth oxychloride/multi-walled carbon nanotube ((BiO)₂OHCl/MWCNT) nanocomposite is presented for the simultaneous detection of Cd 2+ and Pb 2+ . The material was synthesized via a one-step alkaline hydrothermal assembly, which ensures the uniform dispersion of MWCNTs to establish a conductive network for electron transport. The hydroxyl-induced anion-layer modulation optimizes the internal electronic environment to accelerate interfacial charge transfer. Concurrently, surface hydroxyl groups provide specific coordination interactions, improving the adsorption affinity and accumulation efficiency of the target metal ions. Under optimized conditions in sodium acetate-acetic acid buffer (pH 5.0), the sensor exhibits linear detection ranges of 10–300 μg/L for both Cd 2+ and Pb 2+ , with limits of detection (LOD) of 0.226 μg/L and 0.412 μg/L (S/N = 3), respectively. The proposed sensor exhibits good repeatability, reproducibility, and anti-interference capability, and was successfully applied to the analysis of spiked seawater samples. Download: Download high-res image (189KB) Download: Download full-size image
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高影响因子
ANALYST
·
2025
·
IF 3.3
Zhixiang Liang,Huimin Li,Junlei Han,Jun Chen,Jiemeng Ding,Wenteng Tang,Minghui Wang,Qi Meng,Lei Zhang,Zetao Zhang,Li Wang
Cardiovascular toxicity is a key safety indicator that has to be evaluated in the process of new drug development. To enable high-throughput and multiparametric assessment of cardiomyocyte function, we developed a 32-well high-throughput microelectrode array (MEA) platform integrated with electrical stimulation. Electrode surface modification with PEDOT:PSS-MWCNT nanocomposites significantly enhanced electrochemical performance and signal acquisition fidelity, reducing electrode impedance by 37-fold compared to unmodified Au electrodes. Notably, the built-in electrical stimulation effectively promoted electrophysiological and structural maturation of human iPSC-cardiomyocytes, demonstrated by a 15.47% increase in sarcomere length and 1.73-fold upregulation of connexin-43 expression. The platform's utility was further validated through cardiotoxicity assessment of two representative ion channel modulators, E-4031 (a selective hERG channel blocker) and verapamil (a clinically used calcium channel blocker). Collectively, this study presents an integrated platform that combines functional monitoring with cellular maturation enhancement, offering a powerful tool for cardiotoxicity screening and disease modeling.
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PubMed
高影响因子
POLYMER
·
2026
·
IF 4.5
Lingyu Li,Jiahong Pang,Zhenzhen Tan,Hongjiao Li,Xiuling Cao,Yufeng Tan,Zejun Pu
This paper presents a comprehensive analysis of TPU/MWCNT absorbing composites, which were synthesized through the in-situ polymerization of polycarbonate diol (PCDL), 4,4-diphenylmethane diisocyanate (MDI), 1,4-butanediol (BDO), and hydroxylated multi-walled carbon nanotubes (MWCNT) in varying amounts. The study investigates the effects of MWCNT addition on the microstructure, mechanical properties, thermal stability, and wave absorption performance of the composites. Compared to neat TPU, the composite with 6 wt % MWCNT demonstrates an increase in tensile strength of 3.4 MPa (approximately 8.7%) and an elongation-at-break enhancement of 118%. Additionally, the temperature corresponding to 5% mass loss increases modestly from 308 °C to 324.5 °C. X-ray diffraction (XRD) patterns and scanning electron microscopy (SEM) images confirm that the MWCNT structure is well-preserved within the TPU and exhibits good dispersion. The uniform distribution of MWCNT in the TPU facilitates the formation of effective conductive pathways in the composites, resulting in significant dielectric loss for incident electromagnetic waves. The composites containing 6% MWCNT achieve full-frequency absorption of X-band electromagnetic waves, with a maximum absorption of -20.78 dB and a matching thickness of only 1.1 mm. Furthermore, the incorporation of MWCNT enhances the mechanical properties of the composites while exerting minimal impact on the thermal characteristics of TPU.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Shuanghuan Gu,Sen Wang,Yongju Zhang,Zhixiang Xu,Longhua Xu
The development of sensitive and selective electrochemical sensors for antibiotic detection is critical to ensuring food safety. Herein, we report a novel biomimetic electrochemical sensor using a ternary AuNP/NiFe-LDH/MWCNT heterostructure combined with molecularly imprinted polymers (MIPs) for detecting enrofloxacin (ENR) in food. The AuNP/NiFe-LDH/MWCNT composite was prepared by in-situ reducing HAuCl 4 on a NiFe-LDH/MWCNT backbone, forming a heterojunction structure that enhances charge separation and electron transfer. Electropolymerization of pyrrole with ENR produced highly selective MIP layers. The synergistic integration of high conductivity, abundant catalytic sites, and selective molecular recognition endows the sensor with excellent electrochemical performance. The sensor exhibits a wide linear range (0.05–100.0 μM) and an ultralow limit of detection (LOD) 0.025 μM. It showed superior selectivity, reproducibility, stability, and applicability in complex aquatic food samples, with recoveries of 94.6 % to 103.9 %. This work paves the way for practical, high-precision monitoring of trace antibiotics in food safety applications.
研究领域:
电化学
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食品安全
·
环境监测
·
分析化学
·
纳米材料
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生物传感器
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PubMed
高影响因子
Journal of Macromolecular Science Part A-Pure and Applied Chemistry
·
2021
·
IF 2.168
Xiaoxin Zhang,Shuai He,Weiqiang Lian,Guirong Peng,Shuohai Liu,Zaiji Zhan
In the article, PVDF-based composites reinforced by MWCNT and phenolic epoxy resin were prepared by solution casting method to get a material with excellent mechanical properties and high dielectric properties and breakdown strength when conductor is as filler. The experimental results demonstrate that dielectric constant of m-MWCNT/EP/PVDF composites (εr
= 32 at 100 Hz) is twice times higher than that of the EP/PVDF composites, and is about three times higher than that of the pure PVDF. The dielectric loss is not higher than that of the others (Tan δ = 0.3 at 100 Hz). The breakdown strength of the composites is higher than 100 MV/m, which is superior to most of composites modified with conductors. The breakdown strength for most of composites modified with conductors is under 100 MV/m. The elongation at break of m-MWCNT/EP/PVDF composites keeps 500% and the tensile yield strength increases continuously.
研究领域:
高分子材料科学
·
介电材料
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功能复合材料
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材料物理
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纳米复合材料
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高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 7
·1-12
·
IF 6.232
Kalambate Pramod K.,Dhanjai,Sinha Ankita,Li Yankai,Shen Yue,Huang Yunhui
New multi-walled carbon nanotubes supported on Ti 3 C 2 –MXene and chitosan (chit) composite film–based electrochemical sensor for ifosfamide (IFO), acetaminophen (ACOP), domperidone (DOM), and sumatriptan (SUM) have been developed. Ti 3 C 2 –MXene was synthesized by a fluoride method. Structural and chemical characterizations suggested the successful preparation of Ti 3 C 2 –MXene with clearly seen layered morphology, defined 0 0 2 diffraction peak at 7.5° and complete absence of 1 0 4 plane at 39°. The electrochemical performance of the sensor was investigated by cyclic voltammetry and adsorptive stripping differential pulse voltammetry. The Ti 3 C 2 /MWCNT/Chit modified glassy carbon electrode exhibits enhanced electrocatalytic activities toward the oxidation of target analytes. Excellent conductivity, large surface area, and high catalytic properties of the Ti 3 C 2 –MXene showed synergistic effects with MWCNTs and helped in achieving low detection limits of targets with high selectivity and reproducibility. The assay allows determination of IFO, ACOP, DOM, and SUM in the concentration ranges 0.0011–1.0, 0.0042–7.1, 0.0046–7.3, and 0.0033–61 μM with low detection limits of 0.00031, 0.00028, 0.00034, and 0.00042 μM, respectively. The sensor was successfully applied for voltammetric screening of target analytes in urine and blood serum samples with recoveries > 95.21%. Schematic illustration of the synthesis of self-assembled MXene/MWCNT/chitosan nanocomposite is given and its application to the voltammetric determination of ifosfamide, acetaminophen, domperidone, and sumatriptan described.
Graphical abstract
研究领域:
分析化学
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材料科学
·
医学检测
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Hao Guo,Tingting Zhang,Mingyue Wang,Lei Sun,Junye Zhang,Meng Yang,Fan Yang,Ning Wu,Wu Yang
In this work, a novel sensor based on gold nanoparticle-modified zirconium-metal-organic frameworks (MOF-801) and carboxyl-functionalized carbon nanotube (MWCNT-COOH) composite material was built successfully for electrochemical detection of guanine and adenine in DNA sample, which exhibits diverse advantages such as fast, convenience and high efficiency. Guanine and adenine were detected by the cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Under the optimal conditions, MOF-801/MWCNT-COOH/ AuNPs/GCE delivered linear DPV responses to guanine in the range of 0.8 ~ 60, 60 ~ 180 μM and the adenine in the range of 0.8 ~ 60, 60 ~ 180 μM with the low detection limit of 0.09 μM for guanine and 0.08 μM for adenine, respectively. The advantages of this method include simplicity, rapidity, high sensitivity, good selectivity as well as low cost. The modified GCE was successfully applied to the analysis of guanine and adenine in DNA samples.
研究领域:
生物化学
·
分析化学
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高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Hao Guo,Tian Fan,Wenqin Yao,Wenhu Yang,Ning Wu,Hui Liu,Mingyue Wang,Wu Yang
Herein, a novel electrochemical sensor based on ZIF-67/MWCNT-COOH/Nafion composite was designed and prepared for simultaneous detection of 4-aminophenol (4-AP) and acetaminophen (AMP). The electrochemical behaviors of the 4-AP and AMP on the ZIF-67/MWCNT-COOH/Nafion electrode were explored via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The results exhibited that the designed electrochemical sensor possessed superior electrocatalytic activity for 4-AP and AMP, which was attributed to the highly ordered porous structure of ZIF-67, the outstanding electrical conductivity and high electrocatalytic activity of MWCNT-COOH. Under optimization conditions, the DPV response of the prepared electrode depicted a wider linear response concentration range of 0.2 to 200 μM for 4-AP, and 0.1 to 100 μM for AMP, respectively. And the lower detection limits (LOD) of 0.01 and 0.07 μM were obtained for 4-AP and AMP, respectively. More importantly, the acquired electrode was applied to Yellow river water and Paracetamol tablets for analysis of 4-AP and AMP, which exhibited satisfying recovery of 98.2% ~ 106.7% for 4-AP and 94.7% ~ 99.6% for AMP, respectively. In a word, the constructed electrochemical sensing platform delivered a promising potential in real application.
研究领域:
分析化学
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环境科学
·
药物分析
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Hao Guo,Bingqing Liu,Zhilan Pan,Lei Sun,Liping Peng,Yuan Chen,Ning Wu,Mingyue Wang,Wu Yang
s Covalent organic frameworks (COFs) have received tremendous interest due to their structural diversity and versatility. These unique physicochemical properties make them exhibit great application potential in the field of electrochemical sensor. In this study, an imine bond-linked COF with porosity and large specific surface area was fabricated by a dehydration condensation reaction between 1, 3, 5-tris(4-formylphenyl)benzene (TFPB) and 1, 3, 5-tris(4-aminophenyl) benzene (TAPB) and combined with high electrical conductivity of oxidized multi-walled carbon nanotube (Ox-MWCNT). The structure of the COF and the resulted composite material were confirmed through a series of characterization techniques, including Fourier-transform infrared spectroscopy, powder X-ray diffraction, scanning electron microscopy and thermogravimetric analysis , then a co-modified glassy carbon electrode was constructed for simple, sensitive and selective electrochemical recognition of dopamine (DA) and uric acid (UA). The fabricated electrochemical sensor displayed a strong current response to both DA and UA in the phosphate buffer solution (PBS) at pH = 6.5. The synergistic effect between COFs and Ox-MWCNT effectively improved the analytical sensitivity for the target analytes. Under optimized experimental conditions, the method showed good performance for DA and UA in the concentration range of 0.6–250.0 μM with low detection limits of 0.073 μM and 0.063 μM (S/N = 3), respectively. Moreover, the proposed sensor exhibited high selectivity , longtime stability, desirable repeatability and acceptable reproducibility and can be used to analyze simultaneously DA and UA in biological and medicine samples with satisfactory results. Our work not only provides a simple way to detect DA and UA quantitatively in real samples, but also offers a new platform for COF-based composite application in electrochemical sensing .
研究领域:
分析化学
·
材料科学
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高影响因子
International Journal of Polymeric Materials and Polymeric Biomaterials
·
2017
·
IF 1.515
Yan-Ling Luo,Xue-Yin Zhang,Jing-Yu Fu,Feng Xu,Ya-Shao Chen
Novel poly(N-isopropylacrylamide)/carboxymethyl chitosan/multiwalled carbon nanotube semi-interpenetrating nanohybrid hydrogels were prepared, and the chemical structure and morphology were characterized. The prepared hydrogels showed temperature and pH dual-responsiveness, and the one containing multiwalled carbon nanotubes (MWCNTs)–COOH possessed high maximal swelling ratios. The phase transition produced at pH of 6.8–7.4 and temperature of 35–40°C, hinging on the system compositions and charge ratios. The hydrogels were used to load hydrophilic anticancer drug, with high entrapped efficiency of about 44%. The drug release changed with temperature, pH, and MWCNTs–COOH contents. The designed hydrogels can be used for site-specific target delivery of protein or hydrophilic anticancer drug.
研究领域:
材料科学
·
生物医药工程
·
药剂学
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高影响因子
RSC Advances
·
2015
·Vol. 6
·期 6
·4695-4704
·
IF 3.84
Jiyong Fang,Yan Wang,Wei Wei,Zheng Chen,Yunxi Li,Zhi Liu,Xigui Yue,Zhenhua Jiang
A nanocomposite consisting of nanoparticles decorated by multi-wall carbon nanotubes (MWCNTs/Ag/Co0.2Fe2.8O4) was designed and synthesized to meet requirements for a wider, thinner, and stronger electromagnetic (EM) wave absorber. The structure and morphology analysis revealed the structure of the nanocomposite absorber. The introduction of Ag nanoparticles can increase the interface by bringing stronger coupling into the heterogeneous nanocomposite, whereas Co0.2Fe2.8O4 can introduce dipoles and magnetic loss as well as additional interfaces into the absorber. The electromagnetic parameters of absorber and wax composite with different absorber contents were measured in the range of 2–18 GHz to evaluate its EM wave attenuation performance. With an absorber loading of 20%, at a low thickness of 1.8 mm, the highest attenuation effectiveness value of −52.4 dB can be achieved at 10.2 GHz. Moreover, with absorber thicknesses from 1.1 to 3.7 mm, RL values below −20 dB can be achieved over a wide frequency range from 4.0 to 18 GHz covering the C band, the X band and the Ku band. Consequently, the nanocomposite absorber has an excellent EM wave attenuation ability with the characteristics of a wide absorption band (4–18 GHz), strong absorption (−52.4 dB) and low absorber thicknesses (1.1–3.7 mm). The excellent EM wave absorbency can be attributed to strong interfacial and dipole polarization, dielectric loss caused by Debye dipolar relaxation and the combination of dielectric loss and magnetic loss. Such a nanocomposite could serve as an attractive candidate for EM wave attenuation applications in the future.
研究领域:
材料科学
·
电磁学
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高影响因子
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