JOURNAL OF ALLOYS AND COMPOUNDS
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2024
·
IF 5.8
Jiana Hu,Caiyun Liang,Jiadong Li,Chuanwei Lin,Yongjiu Liang,Dewen Dong
2D transition metal carbide/nitride (MXene) nanomaterials have prospective applications in high-performance microwave absorption (MA). However, the excessively high permittivity, absence of magnetic loss, and susceptible oxidizability of MXene severely hinder the enhancement of its MA properties. Here, we used a facile organic solution–phase thermal decomposition method to prepare dielectric–magnetic MXene@CoNi nanocomposites with heterojunctions , which can effectively prevent the oxidation of MXene . Subsequently, the MXene@CoNi nanocomposites were integrated with magnetic CoNi alloys, MXene microspheres (MXene MPs), and a silicon rubber (SR) matrix to construct multilayered CoNi/MXene@CoNi/MXene MPs/SR composites by casting and curing. Benefiting from the multilayered structure and complementary effects of the dielectric and magnetic components, the multilayered CoNi/MXene@CoNi/MXene MPs/SR composites composed of matching, absorbing, and reflective layers showed a remarkable minimum reflection loss of −53.3 dB and an ultra-broad effective absorption bandwidth up to 11.12 GHz at a thickness of 2.96 mm. These results demonstrated the developed multilayered composites are promising candidates for high-performance MA. Our study provides new insights into the development of ultra-broadband MXene-based absorbent materials.
研究领域:
材料科学
·
电磁学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jinming Ye,Taiwei Zheng,Qiong Xiao,Qiuming Yang,Huifen Weng,Yi Ru,Xiaoyan Zhuang,Anfeng Xiao
The spatial configuration and bonding conditions of polysaccharide microspheres make it difficult to distinguish molecules with similar hydrophobic properties in practical applications. Fortunately, medium modification offers more flexible chromatography conditions and higher selectivity, providing new solutions for complex purification environments. We synthesized hydrophobic composite core-shell agarose microspheres equipped with hydrophobic ligands and investigated the effects of hydrophobic ligand coupling on the morphology, particle size, pressure resistance, functional group change and protein adsorption capacity of microspheres. On this basis, the protein adsorption kinetics indicated that the best coupling temperature and time of phenyl and butyl were 40 °C, 8 h and 20 °C, 16 h, respectively. When the concentration of (NH 4 ) 2 SO 4 salt in the mobile phase is 2 M, and the pH is 7.0, the dynamic adsorption capacity of the medium for BSA reaches 12.6 mg/mL. The separation, purification efficiency, and resolution of these microspheres in a crude enzyme solution containing flavin monooxygenase improved significantly, demonstrating the practical implications and potential applications of this research. Overall, our findings reveal that this natural polysaccharide core-shell medium increases the modifiable sites of ligands, and can modify ligands in both the inner and outer layers, exhibiting its potential application in biomolecular separation.
研究领域:
生物化学
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分离科学
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材料科学
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DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2024
·
IF 8.2
Xingyu Wu,Jingyi Wang,Yuantong Lei,Haoyang He,Zhibo Lei,Xinjuan Huang,Hong Xiao,Ganxue Wu,Zhenxing Zeng,Yingjun Wang,Liping Huang,Fei Shen,Shihuai Deng,Xiaoping Gao,Zhuoyao Fang,Dexin Fang
Over the past decades, considerable efforts have been made to find useful solutions for phosphate pollution control . The state transition of nanomaterials from freely dispersed to encapsulated provides a realizable route for their application in phosphate elimination. The separation convenience offered by encapsulation has been widely recognized, however, the unique binding mode of nanostructures and phosphate in the confined space remains unclear, limiting its further development. Here, carboxymethyl cellulose (CMC) microspheres were used as hosts to deploy layered double hydroxide (LDH) nanoparticles . On this basis, we described an attempt to explore the adsorption behavior of LDH and phosphate in the microsphere space. Compared to their freely dispersed analogues, LDH particles exhibited higher structural stability, wider pH adaptability, and better phosphate selectivity when spatially confined in the CMC microsphere. Nevertheless, the kinetic process was severely inhibited by three orders of magnitude. Besides, the saturated phosphate adsorption capacity was also reduced to 74.6 % of the freely dispersed system. A combinative characterization revealed that the highly electronegative CMC host not only causes electrostatic repulsion to phosphate, but also extracts the electron density of the metal center of LDH, weakening its ability to act as a Lewis acid site for phosphate binding. Meanwhile, the microsphere encapsulation also hinders the ion exchange function of interlayer anions and phosphate. This study offers an objective insight into the reaction of LDH and phosphate in the confined microsphere space, which may contribute to the advanced design of encapsulation strategies for nanoparticles.
研究领域:
环境科学
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材料科学
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DOI
PubMed
高影响因子
AMB Express
·
2025
·Vol. 15
·期 1
·1-12
·
IF 3.7
Hu Yanli,Xia Yingjun,Mo Huiwen,Zhang Li,Cao Wenjian,Fang Rui,Zhao Junlong
African swine fever (ASF) is a contagious viral disease in pigs, caused by the African swine fever virus (ASFV). Currently, there are no effective vaccines and drugs for ASFV, making diagnostic methods crucial for the prevention and control of ASF. In this study, the ASFV p30 protein was successfully expressed using a prokaryotic expression system and used as an immunogen to prepare monoclonal antibody (mAb) 2A5. The antigenic epitope recognized by the mAb 2A5 was identified as 58 VKYDIVKSARIYAGQGY 74 . Then, a blue latex microsphere immunochromatographic strip method for detecting ASFV antigens was established. Wherein a rabbit polyclonal antibody (pAb) against p30 stored in our laboratory was coupled with blue latex microspheres to prepare an immune probe, with mAb 2A5 as the test line and goat anti-rabbit IgG as the control line. The immunochromatographic strip exhibited excellent sensitivity, with a minimum detection limit of 10 ng/mL for the p30 protein. It demonstrated good specificity, showing no cross-reactivity with PRRSV, PCV2, PPV, and PEDV. Moreover, it maintained good stability and could be stored for at least 100 days at 37 °C. The concordance rate between the immunochromatographic strip and qPCR test kit was 92.2%. The immunochromatographic strip method can meet the requirements of clinical testing and provide technical support for ASFV diagnosis.
研究领域:
兽医学
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分子生物学
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DOI
PubMed
高影响因子
Theranostics
·
2025
·Vol. 15
·期 9
·4135
·
IF 13.3
Ye Yuan,Longsheng Xu,Yu Zhao,Tizhen Yan,Baobiao Zhuo,Fan Bu,Qian Cai,Youjia Xu,Qing Bi,Yu Tong,Dan Xing,Di Sun,Jianhao Lin
Rationale: Osteoarthritis (OA) is a chronic joint disorder with limited treatment efficacy, necessitating innovative therapeutic strategies. This study explores one-pot-synthesized gelatin microspheres devoid of glutaraldehyde as a novel biomaterial for OA management. Focusing on the Ext1 gene, critical for cartilage development and downregulated in OA, we investigated its restoration and immune regulation using gelatin microspheres cultured with mesenchymal stem cells (MSCs). Methods: OA patients undergoing knee replacement surgery have their lateral compartment (remote zone) and medial compartment (lesion zone) cartilage collected for transcriptomic testing. The differential gene Ext1 is identified, and the expression of immune regulatory genes is examined. MSCs were cultured with gelatin microspheres to evaluate their compatibility and ability to promote cell attachment. The effects of the gelatin microspheres on Ext1 gene overexpression, immune regulation, and OA symptom mitigation were investigated through in vitro and in vivo experiments. Results: OA patients exhibit decreased expression of the Ext1 gene in the medial compartment (lesion zone) cartilage area, accompanied by abnormal expression of immune regulatory genes. The study demonstrated that the gelatin microspheres exhibited excellent compatibility with MSCs and facilitated their attachment. Culturing MSCs with the microspheres led to enhanced overexpression of the Ext1 gene, which is crucial for cartilage growth and development. Additionally, the microspheres regulated immune responses, contributing to a reduction in OA symptoms. Conclusion: This study introduces an innovative therapeutic strategy for osteoarthritis using gelatin microspheres cultured with MSCs. By promoting Ext1 gene overexpression and regulating immune responses, these microspheres effectively mitigate OA symptoms. The findings highlight the potential of this biomaterial as a promising treatment option for OA.
研究领域:
医学
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生物材料学
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DOI
PubMed
高影响因子
ACS Nano
·
2025
·
IF 16
Zhaopeng Liu,Dianlun Wu,Shouhao Wei,Kangqian Xing,Meilin Li,Yue Jiang,Rongfeng Yuan,Guangming Chen,Zhe Hu,Yang Huang,Zhuoxin Liu
Thermal energy, constantly being produced in natural and industrial processes, constitutes a significant portion of energy lost through various inefficiencies. Employing the thermogalvanic effect, thermocells (TECs) can directly convert thermal energy into electricity, representing a promising energy-conversion technology for efficient, low-grade heat harvesting. However, the use of high-cost platinum electrodes in TECs has severely limited their widespread adoption, highlighting the need for more cost-effective alternatives that maintain comparable thermoelectrochemical performance. In this study, a nanocomposite electrode featuring Ti3C2Tx with hollow microsphere structures is rationally designed. This design addresses the restacking issue inherent in MXene nanosheets, increases the electrochemically active surface area, and modifies the original MXene surfaces with oxygen terminations, leading to improved redox kinetics at the electrode–electrolyte interface, particularly in n-type TECs employing Fe2+/3+ redox ions. The optimized n-type TEC achieved an output power of 84.55 μW cm–2 and a normalized power density of 0.53 mW m–2 K–2 under a ΔT of 40 K, outperforming noble platinum-based TECs by a factor of 5.5. An integrated device consisting of 32 TEC units with a p–n connection is also fabricated, which can be successfully utilized to power various small electronics. These results demonstrate the potential of MXene-based composite electrodes to revolutionize TEC technology by offering a cost-effective, high-performance alternative to traditional noble metal electrodes and contributing to efficient low-grade heat harvesting.
研究领域:
材料科学
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能源技术
·
纳米科技
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DOI
PubMed
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2020
·Vol. 26
·期 27
·6006-6016
·
IF 4.857
Shien Pei,Jianfeng Guo,Zhishun He,Liang-ai Huang,Tongzhou Lu,Junjie Gong,Haibo Shao,Jianming Wang
Graphical Sharing a shell : Porous Si-Cu 3 Si-Cu microsphere@C core–shell composites fabricated by an etching/electroless deposition and subsequent carbon coating show excellent lithium storage performance. Low-cost Si-based anode materials with excellent electrochemical lithium storage present attractive prospects for lithium-ion batteries (LIBs). Herein, porous Si-Cu 3 Si-Cu microsphere@C composites are designed and prepared by means of an etching/electroless deposition and subsequent carbon coating. The composites show a core–shell structure, with a porous Si/Cu microsphere core surrounded by the N-doped carbon shell. The Cu and Cu 3 Si nanoparticles are embedded inside porous silicon microspheres, forming the porous Si/Cu microsphere core. The microstructure and lithium storage performance of porous Si-Cu 3 Si-Cu microsphere@C composites can be effectively tuned by changing electroless deposition time. The Si-Cu 3 Si-Cu microsphere@C composite prepared with 12 min electroless deposition delivers a reversible capacity of 627 mAh g −1 after 200 cycles at 2 A g −1 , showing an enhanced lithium storage ability. The superior lithium storage performance of the Si-Cu 3 Si-Cu microsphere@C composite can be ascribed to the improved electronic conductivity, enhanced mechanical stability, and better buffering against the large volume change in the repeated lithiation/delithiation processes.
研究领域:
材料科学
·
能源存储
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Liu Kunliang,Jin Zhicheng,Hu Xiaolong,Yan Dan,Zhang Yu,Zhu Haidong,Teng Gaojun,Xiong Fei
Trans-arterial chemoembolization (TACE) has been a mainstream treatment for hepatocellular carcinoma (HCC), accordingly there are more requirements for embolic agents’ properties, mainly concentrated on biodegradability and imaging function. A new kind of biodegradable multifunctional porous microspheres (BMPMs) with internal coarse plications are ingeniously designed and manufactured, consisting of carrageenan, inhexol and superparamagnetic iron oxide nanoparticle (SPIO). BMPMs’ sound roundness and excellent swelling behavior guarantee them to be smoothly transported into appointed arteries’ ends and achieve satisfactory embolization effect. Porous structure together with sulphate groups on BMPMs’ skeleton weaved by cross-linked carrageenan contributes to a marvelous doxorubicin hydrochloride (Dox) loading capacity over 45 mg Dox per mL of swollen microspheres, as well as a controllable degradation rate by allowing enzymes to infiltrate into BMPMs through holes, degrading 20–35% after two months in vitro . Inner coarse plications enable BMPMs to effectively combine with iohexol via hydrophilic effect and SPIO by blocking, which can further exhibit a decent imaging performance under digital subtraction system (DSA) and magnetic resonance imaging (MRI) for optimization of current TACE and development of a more advanced imageable TACE (iTACE). Safety evaluation and animal experiment manifest that BMPMs are reliable enough and hold great potential and competitiveness of being used in curing HCC.
研究领域:
生物医学工程
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肿瘤学
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材料科学
·
医学影像
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Peng Xiao,Jie Chen,Jun Jia,Liheng Yang,Jiagui Tao,Zhaojie Chu,Chenggang Li,Mengzhou Zhu
Smart thermal management materials possess the ability to sense the surrounding environment and generate corresponding thermal responses. Unlike traditional materials, smart thermal management systems offer advantages such as lower operational energy consumption, the potential for passive or self-regulated operation, and the capability for active thermal control. Herein, depending on the characteristic expansion of thermally expandable microspheres (TEMs) upon heating, a polyvinyl alcohol (PVA)-based graphene composite film with an aligned structure for directional heat transfer was designed to achieve intelligent thermal management. Before the thermal expansion of the microspheres, the composite film (with 50 wt% graphene content) exhibited a high thermal conductivity of 17.61 W/(m·K). After thermal expansion, the thermal conductivity decreased significantly to 0.62 W/(m·K), achieving a thermal conductivity ratio of 28.4 (before-after R). In addition, when dealing with thermal runaway of pouch batteries, the composites can quickly transition from a “high thermal conductive state” to an “thermal insulating state”, avoiding the expansion of the thermal runaway. This composite can respond to abnormal temperature changes in the external environment, and demonstrate significant potential for applications such as preventing thermal runaway in electronic components and batteries.
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DOI
高影响因子
Polymers
·
2021
·Vol. 13
·期 4
·505
·
IF 4.329
Jintao Sun,Fei Cai,Dongzhi Tao,Qingqing Ni,Yaqin Fu
Glass fiber fabrics/hollow glass microspheres (HGM)–waterborne polyurethane (WPU) textile composites were prepared using glass fiber, WPU, and HGM as skeleton material, binder, and insulation filler, respectively, to study the effect of HGM on the thermal insulation performance of glass fiber fabrics. Scanning electron microscopy, Instron 3367 tensile test instrument, thermal constant analysis, and infrared thermal imaging were used to determine the cross-sectional morphology, mechanical property, thermal conductivity, and thermal insulation property, respectively, of the developed materials. The results show that the addition of HGM mixed in WPU significantly enhanced thermal insulation performance of the textile composite with the reduction of thermal conductivity of 45.2% when the volume ratio of HGM to WPU is 0.8 compared with that of material without HGM. The composite can achieve the thermal insulation effect with a temperature difference of 17.74 °C at the temperature field of 70 °C. Meanwhile, the tensile strength of the composite is improved from 14.16 to 22.14 MPa. With these results, it is confirmed that designing hollow glass microspheres (HGM) is an effective way to develop and enhance the high performance of insulation materials with an obvious lightweight of the bulk density reaching about 50%.Keywords:hollow glass microsphere (HGM);thermal insulation;glass fiber fabric;composites
研究领域:
材料科学
·
热物理
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产品关联
DOI
PubMed
高影响因子
Optoelectronics Letters
·
2020
·Vol. 16
·期 4
·293-297
·
IF 0
Li Peng,Zhang Hong-yan,Li Zhi-jun,Zhang Jun
The influence of polyvinylpyrrolidone (PVP) and monoethanolamine (MEA) as surfactants on photoluminescence (PL) of Eu-doped ZnO (ZnO:Eu) has been studied. X-ray diffraction (XRD) results show that there are more Eu 3+ ions to replace Zn 2+ ions into ZnO lattice for ZnO:Eu in the presence of surfactant MEA. From the spectral analysis for ZnO:Eu with different surfactants by Gaussian deconvolution, it can be seen that the use of MEA as a surfactant affects the energy transfer from ZnO host to Eu 3+ ions and leads to three new emission peaks, including UV emission (389 nm), violet emission (411 nm) and green emission (506 nm).
研究领域:
材料科学
·
光学
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产品关联
DOI
FOOD CHEMISTRY
·
2020
·
IF 6.306
Jing Liu,Bin Wang,Huachuan Huang,Dan Jian,Yunan Lu,Yanke Shan,Shouyu Wang,Fei Liu
The ciprofloxacin (CIP) abuse has caused many problems threatening to human health. Here, we design the quantum dot microsphere (QDM) based immunochromatographic quantitative CIP test strip: when the sample under detection contains CIP, the QDM-monoclonal antibody (mAb) probes bound with the CIP and cannot be captured by CIP-bovine serum albumin (BSA) conjugation dispersed on the T lines, reducing the fluorescence intensities. These test strips can provide a low detection limit of 0.05 ng/mL and a wide linear detection range from 0.1 ng/mL to 100 ng/mL in high sensitivity and accuracy as well as good selectivity, reproducibility and stability. Moreover, a smartphone based test strip reader with the size of 85 mm × 48 mm × 44 mm is also fabricated using 3-D printing to automatically and quantitatively detect CIP. The whole process of CIP detection can be finished within 15 min, but only cost ~1 RMB (10 cents).
研究领域:
分析化学
·
纳米技术
·
生物医学工程
·
环境科学
·
食品安全
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）