INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2018
·
IF 4.229
Aisheng Huang,Bo Feng
Pristine graphene oxide (GO) sheets were pretreated with polyethyleneimine (PEI) to prepare PEI-modified GO (PEI-GO), which was further inserted with ZIF-8 crystals to form a novel PEI-GO@ZIF-8 nanocomposite for CO 2 capture. The good dispersion of PEI and interlayer growth of ZIF-8 within the GO sheets is helpful for high CO 2 adsorption. Therefore, the PEI-GO@ZIF-8 nanocomposite show high surface area and enhanced CO 2 adsorption capacity . The adsorption capacity of the PEI-GO@ZIF-8 nanocomposite was six times higher than that of the pristine GO and ZIF-8. The CO 2 /N 2 adsorption selectivity was significantly improved due to amine groups loading which provide more sites for CO 2 adsorption. The preferential adsorption of CO 2 over N 2 makes PEI-GO@ZIF-8 nanocomposite be a promising candidate in the field of CO 2 capture.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Jiamin Zhang,Yingnan Zhu,Jiayin Song,Jing Yang,Chao Pan,Tong Xu,Lei Zhang
Foreign-body reaction (FBR) has been a long-term obstacle for implantable biomedical devices and materials, especially to those that require mass/signal transport between the implants and the body. However, currently, very limited biomaterials can mitigate FBR. In this work, we develop a balanced charged polyelectrolyte hydrogel that can efficiently resist FBR and collagenous capsule formation in a mouse model. Using this new strategy, we can easily tune the antifouling properties of the polyelectrolyte hydrogels by changing the ratio of negatively charged alginate and positively charged poly(ethylene imine). We find that at the optimum ratio where the net charge of hydrogel is neutral, the adhesion of proteins, cells, bacteria, and fresh blood on its surface can be significantly inhibited, indicating its excellent antifouling properties. In vivo studies show that after being implanted subcutaneously, this balanced charged hydrogel can prevent the capsule formation for at least 3 months. Furthermore, immunofluorescent staining results indicate that this balanced charged hydrogel elicits negligible inflammation, significantly reducing macrophage migration to the tissue–implant interface. This flexible and versatile approach holds a great promise for designing a wide spread of new antifouling hydrogels and using as immunoisolation materials for biomedical applications.
研究领域:
生物医学工程
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材料科学
·
组织工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
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2017
·
IF 4.811
Pin Lv,Cheng Zhou,Yulin Zhao,Xiali Liao,Bo Yang
Cyclodextrin-based supermolecular systems have become one of significant nonviral gene delivery carriers. In this study, epsilon-polylysine-grafted-succinic acid-grafted-β-cyclodextrin-LMW PEI (PPC) and adamantane-functionalized poly-(ethylene glycol) derivative (PEG-AD) were synthesized, and PEG-AD was encapsulated into PPC to form the complexes. These complexes were used to condense pDNA to make polyplexes, which biophysical properties, cytotoxicity and transfection efficiencies were studied. The results showed that the polyplexes were less cytotoxic than branched PEI without degrading the transfection efficiency. These findings suggest that the complexes with high stability could be an effective and low-toxicity carrier for delivering nucleic acid to target cells.
研究领域:
生物化学
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分子生物学
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药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2017
·
IF 3.615
Xingzhong Guo,Li Ding,Kazuyoshi Kanamori,Kazuki Nakanishi,Hui Yang
A novel CO 2 sorbent was prepared by modifying polyethyleneimine (PEI) on hierarchically porous silica (HPS) monoliths with well-defined macro-mesopores through wet impregnation method. HPS monoliths before and after functionalization were characterized by scanning electron microscopy (SEM), differential thermal analysis/thermogravimetry (DTA/TG), fourier transform infrared spectroscopy (FT-IR) and nitrogen adsorption/desorption analysis (BET), and the CO 2 adsorption-regeneration properties of as-synthesized sorbents were investigated by thermogravimetric analysis (TG). The effects of loaded PEI amount as well as adsorption temperature and CO 2 partial pressure on the CO 2 adsorption performance of the as-prepared sorbents were also studied. The results showed that the porous structure of HPS-PEI sorbents was preserved after functionalization, while the specific surface area and pore volume decreased with increasing amount of amines to some extent. The use of PEI had a remarkable improvement on the CO 2 adsorption capacity. With the increasing amount of PEI loaded, the CO 2 adsorption capacity improved significantly. The highest CO 2 adsorption capacity of 2.44 mmol (g sorbent) −1 was obtained at 75 °C in the CO 2 partial pressure of 100 kPa for the HPS loaded with 60 wt% PEI. Adsorption/desorption cycles indicated that the PEI-modified HPS sorbents had a good stability and regeneration.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Water Process Engineering
·
2023
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IF 7
Jin Han,Lilan Huang,Jianyu Wu,Haojie Chen,Jian Pan,Jingqi Han,Feng Ma,Jiao Li,Hailin Cong
The construction of catalytic membranes with excellent catalytic efficiency and stability has become a desirable strategy for the treatment of refractory organic wastewater. In this work, polyetherimide/hydroxyl iron oxide catalyst (PEI@FeOOH) catalytic membrane with high performance was developed by of electrospinning and in-situ growth methods for reduction of methyl orange (MO). The immobilization of FeOOH by PEI nanofiber membrane could realize dynamic Fenton catalysis. In the presence of H 2 O 2 (0.62 mM), the PEI@FeOOH catalytic membrane could remove 90 % MO after 4 h, which was much higher than that under static catalysis. This was mainly because that the change of catalytic mode decreased the apparent activation energy of catalysis reaction. Furthermore, the PEI@FeOOH membrane also exhibited good catalytic performance for orange G, methylene blue , phenol and iprofloxacin antibiotics, and excellent reusability. More importantly, benefit from the light absorption property of FeOOH, the PEI@FeOOH membrane exhibited superior catalytic performance in static process when the simulated sunlight was introduced. The synergistic effect of Fenton process and photo-catalysis made the catalytic performance of membrane even higher than that of dynamic Fenton process, providing guidance for dye wastewater treatment .
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Dujuan Hu,Guoying Feng,Man Xu,Cunwen Wang,Yanbo Li
Cyclodextrins (CDs) with unique cavity structures have been used as materials for nanofiltration membrane fabrications. In the present work, the activated CD (O-CD), oxidated by NaIO 4 , and polyethyleneimine (PEI) were co-deposited on a hydrolyzed polyacrylonitrile support, post-treated by glycerol protection and heating treatment, to prepare nanofiltration membranes with low molecular weight cut-off (MWCO). As the cavities in CD present and the aldehyde groups introduced after oxidation, the O-CDs were expected to crosslink the PEI layer and provide extra permeating channels. The filtration experiments showed that the incorporation of O-CDs improved the permeances of the O-CD-PEI/HPAN nanofiltration membranes. The performance can be tailored by the control of the loading or the oxidation degree of the O-CD. At optimal conditions, the permeance increment was nearly double (from 9.2 to 21.1 Lm -2 ·h −1 ·bar −1 ). While the selectivity was without significant sacrifice, the rejection of PEG 200 remained around 90%. Meanwhile, the membrane stability was demonstrated by pro-longed filtratiing a PEG 200 aqueous solution. The constant permeance and rejection confirmed the O-CD-PEI/HPAN membranes were stable. The incorporation of activated CD in PEI offers a facile strategy to promote the permeance of PEI-based membranes.
研究领域:
材料科学
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化学工程
·
膜技术
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产品关联
DOI
PubMed
高影响因子
BIOMATERIALS
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2025
·
IF 12.9
Siting Sheng,Huiling Zhao,Lirui Liu,Dan Chen,Xingdi Wu,Chujun Liu,Xinyu Ma,Jing-Wei Xu,Jian Ji,Haijie Han,Wen Xu
Uveitis, a frequently recurrent inflammatory condition of the uvea, poses a significant risk of visual impairment and blindness, primarily due to the excessive generation of reactive oxygen species (ROS) and the activation of signaling pathways that propagate inflammatory responses. Despite the widespread use of corticosteroid eye drops as a standard treatment, these therapies are hindered by limited efficacy, adverse side effects, and poor ocular bioavailability. To address these challenges, polyethyleneimine (PEI)-modified polydopamine (PDA) carrying microRNA-132-3p (miR-132), namely PEI/PDA@miR-132, was developed to simultaneously neutralize ROS and attenuate inflammation in experimental models of acute and chronic uveitis. Mechanistically, PEI/PDA@miR-132 demonstrated remarkable efficacy by suppressing ROS production, inhibiting the pro-inflammatory polarization of macrophages, and downregulating the I κ B α /nuclear factor-kappa B (NF- κ B) p65 signaling pathway. These effects culminated in the reduction of pro-inflammatory cytokines and mitigation of apoptosis. Therapeutically, PEI/PDA@miR-132 provided significant relief from hallmark symptoms of uveitis, including iris congestion, inflammatory exudation, and retinal folds, while exhibiting superior retinal safety compared to commercially available dexamethasone. Furthermore, it showcased excellent biocompatibility, positioning it as a promising therapeutic strategy for managing oxidative stress- and inflammation-driven diseases such as acute and chronic uveitis.
研究领域:
药理学
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眼科
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纳米医学
·
炎症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Chang-Yuan Cheng,Yong Xiang,Jing-Ping Sun,Wen-Cai Bai,Zhou-Xuan Zang,Ou-Yang Liu,Li Xu
In this study, we crafted nitrogen-laden microspheres known as PEI-GA, employing a straightforward, single-step synthesis at ambient temperature. We further validated their capacity as autonomous adsorbents, capable of achieving efficient, targeted, and swift extraction of gold ions (Au(III)) from aqueous media. The high nitrogen content of PEI, combined with its electrochemical adsorption ability, enables effective adsorption and reduction of Au(III) ions into gold nanoparticles, significantly enhancing the adsorption capacity and selectivity. PEI-GA exhibits an ultra-fast adsorption rate, achieving over 99 % Au(III) recovery in just 1 min at a concentration of 100 mg/L (m/V = 0.5 g/L). Moreover, even at higher concentrations (300 mg/L), the process only takes 5 min. The maximum adsorption capacity of PEI-GA reaches 2078 mg/g, following the Langmuir model and pseudo-second-order kinetics. PEI-GA also demonstrates excellent selectivity and recyclability, recovering over 95 % of gold ions from simulated e-waste solutions and maintaining 90 % recovery efficiency after five cycles. DFT calculations suggest that AuCl₄ − tends to form multicentric coordination with N atoms in PEI-GA. This study highlights the cost-effectiveness of PEI-GA for Au(III) recovery, which can be further optimized through calcination or regeneration.
研究领域:
环境科学
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材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Shaoliang Zhu,Bingtao Zhao,Yaxin Su
High-efficiency and cost-effective adsorbents are crucial to dry capture of carbon dioxide (CO 2 ). The polyethyleneimine (PEI) was co-impregnated with tetraethylenepentamine (TEPA) on γ-alumina (Al 2 O 3 ) to synthesize the adsorbent and enhance the capture process. The influence of amine loading and operating parameters on CO 2 adsorption was investigated, and the process parameters were modeled. The results depict that the optimal loading is 50 % when functionalized either PEI or TEPA individually, which is 3.7 and 4.6 times higher than γ–Al 2 O 3 . The CO 2 capacity of γ–Al 2 O 3 functionalized with multiple amines (30 %PEI+20 %TEPA) is 2.65 mmol/g, due to the synergies of the two amines to increase the chance of CO 2 binding to the sites. Regeneration performance illustrates that the adsorbent remains at 90.2 % of the initial capacity after seven tests. The maximal capacity of 2.70 mmol/g occurs at 70 °C. Modeling results indicate the kinetics can be evaluated by the Avrami model (R 2 > 0.990) with the activation energy of 5.65 kJ/mol. The process is controlled by physical–chemical adsorption, influenced by intraparticle diffusion, as described by the deactivation model. Finally, a comparison and assessment were conducted for their techno-economic performances, and the pathway to applications was also proposed in engineering practice.
研究领域:
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
POLYMER COMPOSITES
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2018
·
IF 1.943
Ping Han,Lichun Ma,Guojun Song,Longlong Shi,Zheng Gu,Xiaoru Li,Chao Yang,Gang Wang
In order to investigate the effects of molecular weights on the interfacial properties of carbon fibers (CFs) reinforced epoxy composites, dendritic polyethyleneimine (PEI) with different molecular weights were grafted onto CF surface by a simple and efficient method. The microstructures, interfacial, and mechanical properties of modified CFs were researched. Raman spectra and X-ray photoelectron spectroscopy (XPS) confirmed the successful growth of PEI dendrimers. Scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (HRTEM) images showed that grafting PEI could improve surface roughness, and this effect was more pronounced with molecular weight increasing. When the molecular weight of PEI is 600, the interfacial shear strength (IFSS), interlaminar shear strength (ILSS), and flexural strength of CFs/epoxy composites were enhanced by 83.6%, 46.1%, and 22.3% compared with those of unmodified ones, respectively. The fractured surface of composites showed a great enhancement of interfacial adhesion. Moreover, the interfacial enhancement mechanisms and failure modes were also discussed. POLYM. COMPOS., 40:E1525–E1536, 2019. © 2018 Society of Plastics Engineers
研究领域:
材料科学
·
复合材料工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Bio Materials
·
2019
·
IF 0
Jiantao Yu,Jing Li,Shiyao Zhai,Li Lin,Kui Wang,Bin Tang,Hong Meng,Leilei Tian
Polymerization of small interfering RNA (siRNA) has been demonstrated as a promising strategy to improve siRNA delivery, which will change the low-charge and rigid properties of single siRNA and enhance its electrostatic interactions with cationic polymers. For such polymerization strategy, a major breakthrough is still needed to fully eliminate chemical processes and further improve the nanocomplex-forming ability of polymerized siRNAs. Herein, the extremely strong interaction between the DNA product of rolling circle amplification (RCA) and linear poly(ether imide) (PEI) has been disclosed; accordingly, a stable nanocomplex is formed just at its charge neutralization point, which benefits from the high molecular weight of the RCA product (>3 000 000 Da). In addition, as the sequence of the RCA product is determined by the cyclic template, the programmable nature of DNA can simplify the optimization process and maximize the hybridization efficiency between RCA and sticky siRNAs, realizing a superior siRNA polymerization efficiency. Depending on these two effects, the RCA DNA is utilized as a cocarrier material to organize siRNA polymerization and substantially reduce the usage amount of PEI, which greatly improves RNAi efficiency of PEI/RCA-siRNA polyplex both in vitro and in vivo, providing evidence that RCA DNA is a promising material to promote the RNAi-based therapeutics.
研究领域:
分子生物学
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纳米医学
·
治疗开发
✓ 已验证
产品关联
DOI
PubMed
RSC Advances
·
2016
·Vol. 6
·期 72
·67875-67882
·
IF 3.289
Weijun Fang,Chen Han,Huabing Zhang,Wenmei Wei,Rui Liu,Yuxian Shen
Pathogenic bacteria can lead to food poisoning and serious infectious diseases, and place a large burden on human health. A method for rapid capture and removal of the harmful bacteria from the contaminated source is essential and important. In this study, two types of amine group functionalized magnetic nanoparticles were successfully fabricated for effective capture of bacterial pathogens. These magnetic nanoparticles with a positive-charge surface strongly interacted with the negative-charge bacterial cell wall via electrostatic attractions to exhibit efficient adsorptive ability of a broad spectrum of bacterial pathogens. Owing to more cationic amine groups, the bacterial capture capacity of Fe3O4@sSiO2-PEI nanoparticles (PEI-MNPs) for E. coli BL21 was three times that of Fe3O4@sSiO2-NH2 nanoparticles (NH-MNPs), making them promising for practical applications. More importantly, the PEI-MNPs also showed excellent bacterial capture efficiency at a low concentration due to the multivalency effect that appeared in our system.
研究领域:
生物医学工程
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）