ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2016
·Vol. 408
·期 30
·8771-8778
·
IF 3.125
Zhang Fang Fang,Zou Hong Yan,Lan Jing,Wang Hong,Huang Cheng Zhi
It is very important to be able to accurately and rapidly measure the cholesterol level in the human body, as cholesterol is associated with various diseases, such as Alzheimer’s disease. In this work, a novel method of detecting cholesterol using chemiluminescence (CL) based on a newly prepared semiconductor catalyst, Cu 2− x
Se nanoparticles (Cu 2− x
Se NPs), was developed. It was found that the Cu 2− x
Se NPs strongly enhanced the CL signal by producing a large number of reactive oxygen species (ROS) in the luminol–Cu 2− x
Se NPs system. Based on the UV-vis-NIR absorption spectra, zeta potential, CL spectrum, and an investigation of the ROS, a possible mechanism for the CL was proposed. This CL-based method was successfully applied to determine cholesterol. It was found that the enhanced CL was proportional to the concentration of cholesterol over the range of 82 nM to 1.96 μM with a detection limit of 0.062 nM, and that added cholesterol was successfully detected in human serum with a mean recovery of 97 %.
研究领域:
医学诊断
·
生物化学
·
纳米材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Solar RRL
·
2021
·Vol. 6
·期 1
·2100778
·
IF 8.582
Hongling Guo,Rutao Meng,Long Hu,Chun-Ho Lin,Yali Sun,Yue Liu,Jianyu Wu,Zhan Shen,Dewei Chu,Gang Wang,Li Wu,Guangxing Liang,Shifu Xiong,Fangfang Liu,Yi Zhang,Tom Wu
In spite of the merits such as Earth abundance and high performance, Cu 2 ZnSn(S,Se) 4 (CZTSSe) solar cells suffer from unfavorable Sn Zn antisite defects and complexes, which act as nonradiative recombination centers and deteriorate the open-circuit voltage ( V OC ). Therefore, the management of Sn composition is the prerequisite for achieving high-efficiency CZTSSe photovoltaic devices. At present, the Sn-related composition and defect modifications at different selenization pressures remain unclear, which restrain the development of efficient kesterite solar cells. Herein, a facile yet effective strategy to accurately adjust the Sn content in CZTSSe films by simply optimizing the selenization pressure is demonstrated. Compared with the widely used atmospheric pressure, it is unveiled that the appropriate negative pressure (0.7 atm) can tailor the optimal Sn content in the absorber layer, influencing both the Sn-related defects and the microstructures. In contrast, a lower (0.4 atm) and a higher (1.3 atm) selenization pressure results in undesirable deep Cu Sn defects and a Sn(S,Se) 2 secondary phase, respectively. A champion device fabricated at this optimal selenization pressure (0.7 atm) exhibits a power conversion efficiency of 11.32% with a V OC of 0.496 V. This study paves the path toward highly efficient kesterite solar cells by tailoring the composition-dependent defects.
研究领域:
材料科学
·
太阳能电池技术
✓ 已验证
产品关联
DOI
高影响因子
Solar RRL
·
2023
·Vol. 7
·期 9
·2300006
·
IF 7.9
Yue Jian,Tianliang Xie,Litao Han,Lei Cao,Lijing Wang,Wenhui Zhou,Zhengji Zhou,Dongxing Kou,Yuena Meng,Yafang Qi,Shengjie Yuan,Sixin Wu
Thermally evaporated Se, including the molecules of Se 2 , Se 5 , Se 6 , Se 7 , and Se 8 in the vapor at 550–600 °C, is widely used for the selenization of CZTSSe films. However, active small-molecule Se 2 tends to form large clusters of Se atoms at saturation vapor pressure, resulting in the large Se deficiency and poor crystallization of CZTSSe films. To regulate the time for Se to reach saturation vapor pressure and promote the role of active small-molecule Se, the evaporation area of Se is controlled. Then the corresponding grain growth mechanism of CZTSSe films and device efficiency are systematically investigated. The results demonstrate that the appropriate evaporation area of Se can not only optimize the time for Se vapor to reach saturation, promote the rapid reaction crystallization between the precursor films and active Se 2 , but also inhibit the nucleation at the CZTSSe/Mo interface, thus making the CZTSSe films show a perfect top-down grain growth mode. By preliminary optimization, when the evaporation area of Se is 245 mm 2 , a large-grain spanning monolayer CZTSSe thin film is obtained; meanwhile, a device with a high efficiency of 12.39% is achieved. This study provides a new selenization strategy for improving the crystallinity of CZTSSe thin films.
研究领域:
材料科学
·
太阳能电池研究
✓ 已验证
产品关联
DOI
高影响因子
Nature Energy
·
2025
·
IF 60.1
Xiang Chunxu,Yuan Mingjun,Ding Chuan’an,Zheng Yuanyuan,Li Yize,Hu Xiaole,Zhang Jie,Li Xinyu,Ma Chengfeng,Wang Shaoying,Yan Weibo,Yang Chunlei,Huang Wei,Xin Hao
Solution processing has great advantages for emerging thin-film solar cells but remains a big challenge for multielemental inorganic films due to complicated phase evolution and grain growth during crystallization. Here we report the fabrication of uniform, large-area Cu 2 ZnSn(S,Se) 4 (CZTSSe) films and solar modules from solution. By tuning the thiourea/metal ratio to increase film porosity—thereby promoting more uniform vertical reaction and lateral grain growth—we improved the uniformity of CZTSSe films and achieved a single-cell efficiency of 13.4% and a solar module efficiency of 8.91%. We further optimized the module structure to reduce non-ideal contact and patterning-induced shunt and resistive losses, resulting in a champion CZTSSe module with a National Renewable Energy Laboratory-certified efficiency of 10.1%. This module also exhibits the lowest cell-to-module loss in open circuit voltage and current density among state-of-the-art emerging thin-film solar modules. Our work demonstrates the viability of solution processing to deposit uniform, large-area CZTSSe film and efficient solar modules, advancing the development of the technology.
研究领域:
材料科学
·
光伏技术
·
薄膜太阳能电池
·
无机功能材料
·
能源材料
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR RECOGNITION
·
2018
·Vol. 31
·期 8
·e2714
·
IF 1.868
Juxin Yin,Jianjian Zhuang,Shaowu Lv,Ying Mu
Excessive reactive oxygen species (ROS) levels are harmful to the body. The peroxidase, GPx, and the superoxide dismutase, SOD, are important antioxidant enzymes for preventing ROS-induced damage. Se-CuZn-65P is an enzyme mimetic with dual GPx and SOD antioxidant function. However, currently, its production is mainly based on the cysteine auxotrophic expression technique, which is inefficient, expensive, and time consuming. In this study, we combined protein engineering and the chemical mutation method to synthesize Se-CuZn-65P. The DNA sequence encoding the 65 amino acid peptide with the desired sequence transformations to incorporate the SOD and the GPx catalytic sites was cloned and expressed in a soluble protein expression vector. The protein yield increased up to 152 mg/L, which is 10 times higher than in previous studies. The SOD and GPx activity of Se-CuZn-65P was high (1181 U/mg and 753 U/μmol, respectively). The binding constant of glutathione was 5.6 × 10 4 L·mol −1 , which shows that Se-CuZn-65P efficiently catalyzed hydrogen peroxide reduction by glutathione. Mitochondrial damage experiments confirmed the double protective role of the Se-CuZn-65P peptide and demonstrated functional synergy between the SOD and the GPx domains, which indicates its potential to be used in the treatment of ROS-related diseases. Our research may give a new thought to increase the yield of mimic.
研究领域:
生物化学
·
分子生物学
·
药理学
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2025
·
IF 6.7
Rui Zhang,Meilan Liu,Lin Bao,Huanchen Yan,Huahui Feng,Danyi Huang,Ying Ding,Min Chen
Chondrodysplasia presents with abnormal chondrocyte differentiation and altered cartilage extracellular matrix, which restricts cartilage and bone growth. Kartogenin (KGN) is recognized as a chondroinductive molecule, whereas the limitation of hydrophobicity and low bioavailability are obstacles to therapy. Nanocarriers for drug delivery can potentially defeat some of the challenges of drug delivery of hydrophobic species. Herein, ROS-responsive core-shell codelivery nanocarriers were developed for chondrogenesis with a core consisting of mesoporous silica nanoparticles (MSN) loaded with KGN and embedded with ultrasmall Prussian blue (USPB), and a shell consisting of selenized hyaluronic acid (Se-HA). MKP@Se-HA nanoparticles effectively improved the bioavailability of KGN. The embedded USPB enhanced structural stability and antioxidant properties, while Se-HA coating targeted chondrocytes via CD44 and employed diselenide bonds as ROS-responsive to achieve KGN release at lesion sites. In vitro and in vivo experiments demonstrated that MKP@Se-HA nanoparticles could promote chondrocyte proliferation and differentiation by upregulating SOX9 and Col II expression. Meanwhile, MKP@Se-HA nanoparticles had a positive effect in the zebrafish chondrodysplasia model by modulating the formation of cartilage matrix and reducing apoptotic cells. Overall, the prepared core-shell codelivery nanoparticles offer a promising strategy for improving chondrodysplasia by synergistically promoting chondrocyte proliferation and differentiation.
✓ 已验证
产品关联
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2020
·Vol. 7
·期 5
·1182-1189
·
IF 5.958
Xianglong Huang,Jianhua Deng,Yuruo Qi,Dingyu Liu,Yuanke Wu,Wei Gao,Wei Zhong,Fang Zhang,Shujuan Bao,Maowen Xu
A rechargeable K–Se battery is emerging as an energy storage system because of its much higher specific capacity than that of the traditional alkali metal-ion batteries, but is facing some critical issues and challenges. Exploiting stable and efficient Se-based cathode materials is one of the key points for addressing the intrinsic drawbacks of this new system. Herein, we developed an effective electrode (nitrogen-doped porous carbon sponge) to serve as an advanced electrode for K–Se batteries. The novel electrode presents good multifunctional characteristics, such as efficient confinement of selenium, valid accommodation of volumetric change, stable conductive framework and promotion of fast electron/ion transportation. Accordingly, desirable electrochemical performances are achieved when the as-obtained Se/carbon composite is used as the cathode of K–Se batteries. This work, via smart and efficient electrode design, unfolds a new idea to accelerate the development of advanced K–Se batteries.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2015
·Vol. 17
·期 17
·3243-3250
·
IF 4.034
Shilin Fu,Kai Cai,Long Wu,Heyou Han
A convenient method was developed for controllable synthesis of homogeneous trigonal Te/Se alloy nanorods (t-Te/Se ANRs) with diverse morphologies, aspect ratios and compositions at room temperature in aqueous solution. These alloy nanorods were formed by a self-seeding process. By varying the molar ratio of TeO2 to H2SeO3 (x(Te : Se)) in the initial precursors, the morphology of t-Te/Se ANRs was transformed mainly via two paths: formation of tri-fold nanorods (TNRs) or single nanorods (SNRs). The nanostructures of TNRs were generated only by using x(Te : Se) ranging from 30 : 1 to 10 : 1, and SNRs were formed using x(Te : Se) ranging from 200 : 1 to 100 : 1 or 2 : 1 to 1 : 1. The microstructures, compositions, and growth mechanisms of these nanorods were also analyzed in detail.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2016
·
IF 7.145
Yanchun Yang,Xiaojiao Kang,Lijian Huang,Daocheng Pan
Alkali metal doping plays a crucial role in fabricating high-performance Cu(In,Ga)(S,Se)2 and Cu2ZnSn(S,Se)4 (CZTSSe) thin film solar cells. In this study, we report the first experimental observation and characterizations of the alloyed LixCu2–xZnSn(S,Se)4 thin films. It is found that Cu+ ions in Cu2ZnSn(S,Se)4 thin films can be substituted with Li+ ions, forming homogeneous LixCu2–xZnSn(S,Se)4 (0 ≤ x ≤ 0.29) alloyed thin films. Consequently, the band gap, conduction band minimum, and valence band maximum of LixCu2–xZnSn(S,Se)4 thin films are profoundly affected by Li/Cu ratios. The band alignment at the LixCu2–xZnSn(S,Se)4/CdS interface can be tuned by changing the Li/Cu ratio. We found that the photovoltaic parameters of the LixCu2–xZnSn(S,Se)4 solar cell devices are strongly influenced by the Li/Cu ratios. Besides, the lattice constant, carrier concentration, and crystal growth of LixCu2–xZnSn(S,Se)4 thin films were studied in detail.
研究领域:
材料科学
·
太阳能技术
·
半导体物理
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2020
·Vol. 22
·期 36
·6019-6025
·
IF 3.117
Junli Wang,Fan Guan,Lijun Zhao,Longhua Li,Junhao Zhang,Tingting Wang
Composition engineering is an active topic of research for optical and electronic (nano)crystals and functional materials. We here demonstrate the control over the ratios and distributions of selenium and sulfur in ternary Sb2(Se,S)3 alloy nanorods (NRs), which were synthesized from a molecular chalcogen precursor, selenium disulfide (SeS2). By increasing the anion/cation precursor ratios (SeS2/SbCl3) from 0.5 : 1 to 1 : 1 and 1.5 : 1, an increase in both the Se fractions and the lengths × diameters of NRs is achieved with the Se and S distributions in Sb2(Se,S)3 varying from homogeneity to inhomogeneity. Within the inhomogeneous NRs obtained at high SeS2/SbCl3 ratios containing excessive chalcogen (Se + S), S decreases but Se increases from the center to the periphery as revealed by EDS elemental analyses performed on individual NRs. In particular, the 1D growth anisotropy of NRs allows for a large chalcogen concentration gradient along the axial direction of the resulting NRs from their middle to the two ends. Such non-uniform Se and S distributions can be rationally interpreted by analyzing the growth kinetics and processes of Sb2(Se,S)3 NRs and would give rise to uncommon (opto)electronic properties towards future nanowire-based devices.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19
Yifan Yuan,Kunpeng Zhao,Qingyong Ren,Haotian Gao,Yuxiang Zhan,Tian-Ran Wei,Ting Zhang,Xun Shi
Flexible thermoelectric materials offer a promising route toward self-powered wearable electronics. The emergence of ductile inorganic semiconductors opens a new paradigm for flexible TE technologies, yet their thermoelectric performance remains far from optimal. Herein, we reveal a pronounced phase-transition hysteresis in the Ag 2 (S, Se, Te) system, where the transition temperature during cooling is 20–40 K lower than that during heating. Leveraging this hysteresis behavior, we successfully stabilize different structural phases at ambient conditions simply by varying the thermal treatment protocol. Compared to the monoclinic phase obtained by slow cooling from high temperature, the orthorhombic phase obtained by liquid-nitrogen treatment exhibits worse plastic deformation but much better electrical transport. A maximum power factor of ∼16 µW cm −1 K −2 and a zT of ∼0.5 near room temperature are achieved in the orthorhombic phase, both of which surpass most reported Ag-based ductile thermoelectric materials. This work provides a new pathway for designing high-performance ductile thermoelectrics.
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2021
·
IF 4.094
Jingying Zhang,Yanchun Yang,Guonan Cui,H. Alata,Yiming Wang,Chengjun Zhu
Substitution of Zn 2+ ionic by Co 2+ ionic is known to suppress the cation disorder of Cu 2 ZnSn(S,Se) 4 thin films , which is helpful to obtain the excellent Cu 2 ZnSn(S,Se) 4 solar cell devices. In our work, the extra trace Co incorporation was added in the solution without affecting the compositions of other elements (i.e. Cu, Zn, and Sn) to enhance the electrical properties of Cu 2 ZnSn(S,Se) 4 thin films . And Co incorporation does not enter into the lattice nor be found in the selenized films after taking effect, but increases the crystallinity , compactness, carrier concentration, and electrical properties of Cu 2 ZnSn(S,Se) 4 thin films samples. By tuning the doping ratios of Co 2+ ionic, the surface roughness of the selenized films can be decreased from 110.2 nm (0 mol %) to 68.90 nm (5 mol %). As 1 mol % of Co 2+ ionic is doped, the carrier concentration of films can be also improved to 4.35 × 10 17 cm −3 from 2.63 × 10 16 cm −3 , and average surface current of films applied 1 V AC voltage can be increased from 2.426 nA to 4.454 nA. The enhanced properties of Co-incorporated films brings hope for the excellent performance of Cu 2 ZnSn(S,Se) 4 solar cells.
研究领域:
材料科学
·
光伏技术
·
半导体薄膜
·
可再生能源
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）