BIOCATALYSIS AND BIOTRANSFORMATION
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2016
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IF 0.892
Danping Qi,Wei Wei,Mingming Diao,Fengxia Lv,Zhaoxin Lu,Xiaomei Bie,Haizhen Zhao
Lipase-catalyzed synthesis of mono- and diesters of 3-O-β-D-galactopyranosyl-sn- glycerol (β-GG) with caproic acid was performed in acetone. The simultaneous production of 1(6’)-monoesters and 1,6’-diesters of β-GG was achieved in this reaction. In order to improve the yield of β-GG esters, four process parameters, enzyme concentration (15 ∼ 25 mg/mL), and substrate molar ratio (caproic acid: β-GG= 1.60 ∼ 2.00 mmol: 0.10 mmol), reaction temperature (40 ∼ 60 °C), and reaction time (8 ∼ 12 h), were optimized via response surface methodology (RSM) employing a three-level-four-variable central composite design. Results showed that enzyme concentration had the most significant (p < 0.0001) effect on the synthesis of β-GG esters. The optimal reaction conditions in acetone were given as follows: Novozyme435 concentration 18.65 mg/mL, molar rate of caproic acid to β-GG 19.46:1, reaction temperature 48 °C, and reaction time 9.83 h. The yield of β-GG esters reached 88.08% under above optimized conditions, which was very close to the predicted value 87.95%. The molar ratio of monoester to diesters was 0.39:0.61. β-GG esters with other fatty acyl chains were synthesized based on the optimized conditions. In vitro antitumor activity indicated that the antitumor activity of β-GG esters was dependent on the nature of fatty acids, such as the length of acyl chain, the degree of saturation, as well as the number of acyl chain.
研究领域:
生物化学
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药物化学
·
癌症研究
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Juan Jian,Long Yuan,Hui Qi,Xuejiao Sun,Le Zhang,He Li,Hongming Yuan,Shouhua Feng
Ni3S2 nanosheets doped with tin (Sn) grown on nickel foam (Sn–Ni3S2/NF) through a facile hydrothermal process were found to be superior water-splitting electrocatalysts. As for overall water splitting (OWS), when the current density is 10 mA cm–2, the required voltage is only 1.46 V. Meanwhile, it exhibits a large current density property and long-time stability (>60 h current–time tests) for both the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER). In order to reach the current densities of 100 and 1000 mA cm–2, Sn–Ni3S2/NF needs overpotentials of 0.17 and 0.57 V for HER, and 0.27 and 0.58 V for OER, respectively. The water-splitting property of Sn–Ni3S2/NF is much better than that of pure Ni3S2/NF or even 20 wt % Pt/C/NF and RuO2/NF. Furthermore, Sn–Ni3S2/NF showed a higher turnover frequency at different potentials, with ∼100% Faraday efficiency for both O2 and H2. The improved activity of Sn–Ni3S2/NF activity for water-splitting is attributed to the doping of Sn, which enhanced the intrinsic activity of Sn–Ni3S2/NF for OWS. This article not only provides a new efficient and stable catalyst for OWS, but also proposes an interface design principle for NF-based high-performance water-splitting materials.
研究领域:
材料科学
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电化学
·
催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Min Yang,Li Liu,Hanxiao Yan,Wen Zhang,Die Su,Jiaxing Wen,Wen Liu,Yiting Yuan,Junfang Liu,Xianyou Wang
The key to the development of wearable electronic equipment lies in the design of flexible batteries, in which the electrodes with outstanding mechanical behavior are quite important. Herein, porous nitrogen-doped Sn/C fibers (P-Sn/C-N Fs) film has been successfully synthesized via simple electrospinning and subsequent calcination process in which folic acid and polymethylmethacrylate (PMMA) play the role of introducing nitrogen and forming pores, respectively. The introduction of nitrogen improves the electronic conductivity of the material, and the presence of porous structure increases the specific surface area. More importantly, when the P-Sn/C-N Fs film is used directly as a free-standing electrode for lithium ion batteries, it exhibits outstanding electrochemical performance. The P-Sn/C-N Fs film exhibits a discharge capacity of 712.1 mAh g −1 at 500 mA g −1 after 500 cycles. Even at the high current density of 5 A g −1 , it displays a high discharge capacity of 429.1 mAh g −1 after 1000 cycles. These findings indicate that the P-Sn/C-N Fs film has the potential to be applied as free-standing anode materials for lithium ion batteries.
研究领域:
材料科学
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电化学
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能源存储
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
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2022
·
IF 5.723
Fanchao Zeng,Yongxia Zhu,Baofang Jin,Yongjun Ji,Lei Shi,Guangwen Xu,Dongxing Fu,Ziyi Zhong,Fabing Su
Multi-component promoters may efficiently improve the catalytic performance of the primary Cu-based catalysts in the Rochow-Müller reaction, but this approach is not well explored, and the roles of the promoters are not very clear. Herein, we report the ZrO 2 -supported CuO catalyst (CuO/ZrO 2 ) modified with a co-promoter of ZnO, Sn, and CuP prepared by a simple dry ball-milling method. The co-promoter could significantly increase the amount of surface adsorbed oxygen and improve the reducing ability of catalysts, facilitating the formation of the active Cu 3 Si phase and further advancing dimethyldichlorosilane ((CH 3 ) 2 SiCl 2 , M2) selectivity and Si conversion in the Rochow-Müller reaction. Compared to the state-of-the-art commercial catalyst, these CuO/ZrO 2 catalysts with the co-promoters all showed enhanced catalytic activity. Especially, the CuO/ZrO 2 catalyst with the co-existence of ZnO, Sn, and CuP promoters achieved the highest M2 selectivity and Si conversion, attributed to its most abundant surface adsorption oxygen and the strongest reducibility. This work opens up a new avenue to improve the catalytic activity of Cu-based catalysts for the Rochow-Müller reaction.
研究领域:
催化
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化学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Duan Zhou,Mouming Zhao,Xiaorong Zhong,Ning Liu,Xuefeng Chen,Daoming Li
1,3-diacylglycerol (DAG) is a natural lipid and known as functional oil. Here, we evaluated the potential of different natural deep eutectic solvents (NADESs) in synthesis of 1,3-DAG through Candida antarctica lipase B (CALB)-catalyzed esterification. Interestingly, we found that the 1,3-DAG content could be increased by 19.21 %, 13.10 %, and 8.74 % in three choline chloride (ChCl)-based NADESs, respectively, compared with that in solvent-free system. Confirmatory experiments demonstrated that NADESs could inhibit the acyl transfer of 1,3-DAG through modulating the water activity of the reaction system. Meanwhile, circular dichroism spectra and fluorescence spectroscopy results indicated that NADESs could not change the secondary structure of CALB, but could affect the tertiary conformation of CALB. Furthermore, molecular dynamics studies showed that the NADESs could induce a more compact tertiary conformation of CALB and enhance the sn -1,3 positional selectivity of CALB. Overall, the NADESs could induce a higher 1,3-DAG yield through inhibiting the acyl transfer of 1,3-DAG and enhancing the sn -1,3 positional selectivity of CALB. This study provides theoretical support for enzymatic production of structural lipids in NADESs.
研究领域:
生物化学
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酶工程
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食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
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2022
·
IF 5.436
Kai-Yao Wang,Yang Liu,Jia-Ying Zhu,Lin Cheng,Cheng Wang
Deep investigations on the synthetic and structural chemistry of heterometallic chalcogenidostannates bear fundamental significance for the establishment of the structure–property relationship that would offer guidance on the functional material innovation. Presented here are four ammonium- and/or alkylammonium-directed M–Sn–Q (M = Zn, Cd; Q = S, Se) compounds, namely, [NH4]7[H3O]3Zn4Sn4S17 (1), [NH4]5[(CH3)2NH2]Zn4Sn5S17 (2), [CH3CH2NH3]22Zn16Sn12Se51(H2O)4·16H2O (3), and [NH4]2CdSnSe4 (4). All four compounds were synthesized in deep eutectic solvents (DESs) or ethylamine aqueous solution, both of which function simultaneously as reaction media and structure-directing agents. Compound 1 consists of discrete P1-[Zn4Sn4S17]10– clusters templated by mixed [NH4]+/[H3O]+ cations. In compound 2, such P1 clusters are bridged by Sn4+ ions in a 4,4-connection mode to form a [Zn4Sn5S17]n6n– framework with three types of cavities (I–III) varying in size. The two smaller cavities (I and II) accommodate NH4+ while the larger one(III) is occupied by [(CH3)2NH2]+, reflecting the rational size-dependence of cations on cavities. Compound 3 features an [Zn16Sn12Se51(H2O)4]n22n– open framework constructed from the 4,3-connection of P1-[Zn4Sn4Se17]10– clusters and {Zn(H2O)}2+ bridges. This linkage mode contributes to a large cage-like subunit (inner dimension: 21.99 × 9.06 Å2) and therefore an ultrahigh porosity that are occupied by [CH3CH2NH3]+ cations and water molecules (volume fraction: 57.7%). Compound 4 exists as a stacking of [CdSnSe4]n2n– chains, which are composed of alternatively arranged {CdSe4} and {SnSe4} tetrahedra, in combination with [NH4]+ cations as both charge-compensating and space-filling agents. Detailed synthetic, structural, and topological analyses were performed on these solid materials, coupled with extensive investigations on their optical and thermal properties. Compound 3 exhibits an efficient Sr2+ adsorption performance, featuring ultrafast kinetics (94.69% in 5 min), high removal rate (98.57% in 20 min) at equilibrium, and high capacity (104.17 ± 23.53 mg g–1).
研究领域:
无机化学
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材料科学
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环境化学
✓ 已验证
DOI
高影响因子
Frontiers of Chemical Science and Engineering
·
2022
·Vol. 17
·期 2
·139-155
·
IF 4.803
Shi Haonan,Gu Xiaoyu,Shi Yinteng,Wang Dandan,Shu Sihao,Wang Zhongze,Chen Jixiang
Porous carbon-encapsulated Ni and Ni–Sn intermetallic compound catalysts were prepared by the one-pot extended Stöber method followed by carbonization and tested for in-situ hydrothermal deoxygenation of methyl palmitate with methanol as the hydrogen donor. During the catalyst preparation, Sn doping reduces the size of carbon spheres, and the formation of Ni–Sn intermetallic compounds restrain the graphitization, contributing to larger pore volume and pore diameter. Consequently, a more facile mass transfer occurs in carbon-encapsulated Ni-Sn intermetallic compound catalysts than in carbon-encapsulated Ni catalysts. During the in-situ hydrothermal deoxygenation, the synergism between Ni and Sn favors palmitic acid hydrogenation to a highly reactive hexadecanal that easily either decarbonylate to n -pentadecane or is hydrogenated to hexadecanol. At high reaction temperature, hexadecanol undergoes dehydrogenation-decarbonylation, generating n -pentadecane. Also, the C-C bond hydrolysis and methanation are suppressed on Ni-Sn intermetallic compounds, favorable for increasing the carbon yield and reducing the H 2 consumption. The n -pentadecane and n -hexadecane yields reached 88.1% and 92.8% on carbon-encapsulated Ni 3 Sn 2 intermetallic compound at 330 °C. After washing and H 2 reduction, the carbon-encapsulated Ni 3 Sn 2 intermetallic compound remains stable during three recycling cycles. This is ascribed to the carbon confinement that effectively suppresses the sintering and loss of metal particles under harsh hydrothermal conditions.
研究领域:
催化
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化学工程
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材料科学
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能量转换
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有机化学
✓ 已验证
DOI
高影响因子
Nutrients
·
2023
·Vol. 15
·期 23
·4929
·
IF 5.9
Lin Zhu,Shuaizhen Fang,Hong Zhang,Xiangjun Sun,Puyu Yang,Jianchun Wan,Yaqiong Zhang,Weiying Lu,Liangli Yu
In this study, the impact ofsn-2 palmitic triacyclglycerols (TAGs) in combination with their ratio of two major TAGs (1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO)) in human milk fat substitute (HMFS) on bile acid (BA) metabolism and intestinal microbiota composition was investigated in newly-weaned Sprague–Dawley rats after four weeks of high-fat feeding. Compared to those of control group rats, HMFS-fed rats had significantly increased contents of six hepatic primary BAs (CDCA, αMCA, βMCA, TCDCA, TαMCA and TβMCA), four ileal primary BAs (UDCA, TCA, TCDCA and TUDCA) and three secondary BAs (DCA, LCA and ωMCA), especially for the HMFS with the highestsn-2 palmitic acid TAGs of 57.9% and OPL to OPO ratio of 1.4. Meanwhile, the inhibition of ileal FXR-FGF15 and activation of TGR5-GLP-1 signaling pathways in HMFS-fed rats were accompanied by the increased levels of enzymes involved in BA synthesis (CYP7A1, CYP27A1 and CYP7B1) in the liver and two key thermogenic proteins (PGC1α and UCP1) in perirenal adipose tissue, respectively. Moreover, increasingsn-2 palmitic TAGs and OPL to OPO ratio in HMFS also altered the microbiota composition both on the phylum and genus level in rats, predominantly microbes associated with bile-salt hydrolase activity, short-chain fatty acid production and reduced obesity risk, which suggested a beneficial effect on host microbial ecosystem. These observations provided important nutritional evidence for developing new HMFS products for infants.Keywords:sn-2 palmitic triacylglycerols;human milk fat substitute;BA metabolism;FXR;TGR5;gut microbiota
研究领域:
营养学
·
微生物学
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代谢学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2024
·
IF 4.1
Xiangfei Ding,Youbing Zhu,Ketao Shi,Zhen Xu,Jian Chen,Zengxi Li,Hui Wang
ZSM-5 zeolite is extensively employed for hydrocarbons cracking to generate light olefins, and its acidity is closely related to the activity and product distribution. In this work, Al-Sn bimetallic ZSM-5 was prepared via a “one-pot” route. Characterizations, including XRD, UV–Vis, XPS, revealed that Sn species were mainly embedded into the zeolite framework as tetrahedral Sn (IV). Moreover, the Sn atoms promoted the formation of Lewis acid sites and reduced the Brønsted acid amount, which effectively inhibited occurrence of side reactions ( e.g. , aromatization, hydrogen transfer) and improved the selectivity of light olefins in n-hexane cracking. Light olefins yield over HZ5[100,200] (Si/Al = 100, Si/Sn = 200) reached 33.4 % due to the appropriate acid property, in comparison with only 15.4 % for HZ5[50,∞] (Si/Al = 50, Si/Sn=∞) containing system. Through optimization of reaction conditions, better catalytic performance (n-hexane conversion of 91.6 % and light olefins yield of 37.6 %) was obtained over HZ5[100,200] under 575 °C with WHSV of 2 h −1 .
研究领域:
催化
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化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2022
·
IF 7.139
Ziqi Wang,Kai Bo,Yong Wang,Yongzhen Wang
The development of ethanol oxidation reaction (EOR) catalysts with high performance is an emerging need of direct ethanol fuel cells (DEFCs). Rational design of support materials of platinum-based catalyst can significantly enhance its catalytic performance for EOR. Here, the highly porous nitrogen-doped carbon material (NC-E) from ZIF-8 was synthesized using a novel and simple method assisted by eutectic salts. Compared with the carbon material obtained from ZIF-8 by traditional calcination (NC-T) and carbon black, the NC-E with high surface area and hierarchical pore structure supported Pt–Sn catalyst exhibits improved electrochemical activity and stability.
研究领域:
材料科学
·
电化学
·
催化
·
能源材料
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Hongbao Li,Zhenli Fu,Hongwei Kang,Rui Wang,Rong Hua,Quanwei Ma,Longhai Zhang,Chaofeng Zhang,Tengfei Zhou
High volumetric capacity and durability anode materials for sodium ion batteries have been urgently required for practical applications. Herein, we reported a Sn-pillared pyknotic graphene conductive network with high-level N-doping. This densely stacked block offers high volumetric Na-ion storage capacity, rapid electrochemical reaction kinetics, and robust structural stability during cycling owing to the high capacity component (metallic Sn ≈847 mAh g–1), high tap density (≈2.63 g cm–3), high conductivity (N doping ≈5 at. %), and strong spatially confined and pillared structure. Moreover, theoretical simulations have indicated that the charge accumulation around the N-doped region is more pronounced compared to the pristine one, and electrons accumulate around the N atom while loss occurs at the Na atom. These studies also suggest that it might possibly contribute to higher conductivity and stronger electrophilic reactivity, thereby resulting in enhanced Na-ion storage performance. As a result, the as-obtained electrode material exhibits competitive volumetric capacity (1462 mAh cm–3 at 0.1 A g–1), cycling performance (1207 mAh cm–3 after 100 cycles), and promising rate behavior simultaneously.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
Metals
·
2025
·Vol. 15
·期 9
·936
·
IF 2.5
Xiangqing Liu,Chenyu Li,Jie Yu,Ruiqi Liu,Min Shang,Xiaolin Su,Jinye Yao,Haitao Ma
This study investigates the synergistic effects of single- and binary-additive systems on the morphology and nucleation mechanism of Sn-Pb alloy electrodeposited coatings. Scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), linear sweep voltammetry (LSV), electrochemical impedance spectroscopy (EIS), and chronoamperometry were applied in order to obtain more information on the action mechanisms of single-additive systems (cinnamaldehyde, PEG-2000, gelatin, vanillin) and binary ones (0.1 g/L cinnamaldehyde + 0.2 g/L PEG-2000) in Sn-Pb electroplating. Results showed that the use of binary-additive systems based on cinnamaldehyde and PEG-2000 significantly improved coating quality, leading to a smooth and uniform surface, dense grains, and a near-eutectic composition (Sn 63.10 wt.%, Pb 36.90 wt.%). This was because the composite additive, through synergistic effects, exhibited the highest cathodic polarization and the largest charge transfer resistance (189.20 Ω cm2), thus inhibiting the electrodeposition process of Sn2+and Pb2+. Chronoamperometry revealed that, unlike single additives (PEG-2000 or cinnamaldehyde), the binary-additive system promoted a transition of nucleation mode to instantaneous nucleation, accompanied by a decrease in the peak current and an extension of the corresponding time. This study provides a theoretical basis and experimental support for understanding the nucleation mode of Sn-Pb electroplating, as well as optimizing the synergistic mechanism of additives.
研究领域:
材料科学
·
电化学
·
表面工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）