BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2019
·Vol. 104
·期 1
·149-155
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IF 1.65
Xie Yan-Li,Jiang Wayne,Li Fen,Zhang Yu,Liang Xiao-Yu,Wang Meng,Zhou Xueqing,Wu Shao-Ying,Zhang Cheng-Hui
This study was intended to develop an environment-friendly controlled release system for spirotetramat in an alginate matrix. Four formulations, starch–chitosan–calcium alginate (SCCA), starch–calcium alginate (SCA), chitosan–calcium alginate (CCA), and calcium alginate (CA) complex gel beads, were prepared by the extrusion–exogenous gelation method. The properties of the formulations were studied. The results showed that the release behaviors of the formulations in water could be well described by the logistic model, and the release occurred through Fickian diffusion. Among the four formulations, SCCA showed the highest entrapment efficiency, drug loading and the slowest release rate. Degradation studies revealed that the SCCA formulation exhibited an obvious slower degradation rate of spirotetramat in soils than the commercially available formulation. The estimated half-life of the SCCA formulation was 2.31, 3.25, and 4.51 days in waterloggogenic paddy soil, purplish soil, and montmorillonite, respectively, when the soils were moistened to 60% of its dry weight. This study provided a possible approach to prolong the duration of spirotetramat and to reduce environmental contamination.
研究领域:
农药科学
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环境科学
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材料科学
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Wentao Shi,Xuan Zhang,Lu Bian,Yao Dai,Zhe Wang,Yanjun Zhou,Shuang Yu,Zhijian Zhang,Peng Zhao,Hong Tang,Qing Wang,Xiaojie Lu
Here, we evaluated osteogenic differentiation in vitro and new bone formation in vivo using an alendronate-loaded chitosan/polycaprolactone scaffold (CS/PCL) in rats with a critical-sized calvarial defect. Through the action of genipin, which has a crosslinking function, alendronate (AL) was anchored throughout the CS/PCL composite scaffold (CS/ [email protected] ) to form an AL sustained release system. We demonstrated that CS/ [email protected] scaffolds significantly enhanced the osteogenic differentiation of ectomesenchymal stem cells (EMSCs) in vitro. Additionally, we explored the possible molecular mechanism of CS/ [email protected] scaffolds in the osteogenic differentiation of EMSCs. This composite scaffold exerted two positive effects on EMSC osteogenic differentiation: 1) the CS/ [email protected] scaffold enhanced EMSC osteogenic differentiation by upregulating bone morphogenetic protein 2, interleukin 10 and laminin expression; and 2) the CS/ [email protected] scaffold promoted the osteogenic differentiation of EMSCs by activating the yes-associated protein (YAP) signaling pathway. YAP and its downstream target transglutaminase are crucial mediators in the osteogenic differentiation of EMSCs. Finally, micro-computed tomography analyses and histology results suggested that the CS/ [email protected] scaffold exhibited a superior capacity to accelerate new and mature bone formation in skull bone defects in Sprague–Dawley rats. This simple and low-cost technology may represent a promising strategy to construct an efficient delivery system to repair bone defects.
研究领域:
生物材料
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组织工程
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骨科
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干细胞研究
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骨再生
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DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Pengfei Han,Zhiming Li,Xin Wei,Liwen Tang,Mengting Li,Zhenyi Liang,Xueqiong Yin,Suying Wei
Ion-imprinted thermosensitive chitosan derivative (ITC) was successfully synthesized through a novel gradient heating process towards applications in heavy metal remediation, using Cu 2+ template paired with N -isopropylacrylamide (NIPAM) monomer. SEM, DSC, FTIR and Raman spectroscopy were used to characterize the structure and properties of ITC. The phase change temperature (PCT) of ITC was 35.31 °C in the heating cycle, whereas in the cooling cycle the PCT for ITC was 26.27 °C. The adsorption capacity of ITC for Cu 2+ at 45 °C (> PCT) was 88.94 mg/g. Desorption rate of 98.90 % was achieved after washing with ultra-pure water at 20 °C (< PCT). An adsorption capacity of 85 mg/g and a desorption rate of 97 % sustained after five cycles reuse. The adsorption capacity for Cu 2+ was measured at 80.23 mg/g under other seven interfering metal ions. The adsorption kinetics and adsorption isotherm fitted pseudo-second-order and Langmuir equation, respectively.
研究领域:
材料科学
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环境科学
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化学工程
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DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 140
·期 3
·e53318
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IF 3.057
Aoqi Li,Yingqing Ye,Peixin Gong,Bo Xiao,Bo Jiang
Compared with traditional conjugates 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS), 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) is an emerging biological coupling reagent and has been used in the amidation of hyaluronic acid. In this paper, DMTMM was used to achieve the amidation of chitosan (CS) with glucuronic acid (GA) in an aqueous medium to generate a GA-CS derivative. The grafting efficacy was preliminarily compared with the EDC/NHS-mediated reaction. As a result, the substitution degree of 17.6% for DMTMM-mediated grafting and 13.1% for EDC/NHS chemistry indicated that DMTMM-mediated synthesis of GA-CS appeared to be more efficient. The reaction kinetics experiments showed that GA-CS derivative with a degree of substitution up to about 26.1% was obtained using equal molar ratios of DMTMM and GA exceeding CS at room temperature. These results indicate that employing DMTMM as a coupling agent is a feasible and promising strategy for the amidation modification of chitosan.
研究领域:
生物化学
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材料科学
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DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
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2022
·
IF 6.056
Alkassoumi Hassane Hamadou,Jiyao Zhang,Chen Chao,Bin Xu
This work evaluated the effect of pectin (P) and chitosan (CH) dual coating on rutin (R) loaded nanoliposomes (NLs). Besides R loaded NLs (RNLs), CH coated RNLs (CH-RNLs) and P coated CH-RNLs (P–CH-RNLs) were prepared. The results showed a size increase of NLs due to the polymer coatings, confirming a successful deposition of CH and P onto the surfaces of NLs. A surface charge reversal was observed after coating RNLs and CH-RNLs with CH and P, respectively. The coating resulted in a significant decrease in encapsulation efficiency (EE) from 88.19% in RNLs to 78.89% in CH-RNLs and 73.44% in P–CH-RNLs. Due to protection provided by the P–CH barrier, P–CH-RNLs displayed better thermal, pH, ionic and oxidative stability. NLs were more stable at 4 °C as compared to 25 °C over 8 weeks, and P–CH-RNLs exhibited the best performance overall. This study revealed P–CH coating as a potential route to produce stable NLs for the delivery of hydrophobic rutin.
研究领域:
药剂学
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食品科学
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材料科学
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DOI
高影响因子
Marine Life Science & Technology
·
2021
·Vol. 4
·期 1
·74-87
·
IF 0
Tong Jianan,Zhou Huiyun,Zhou Jingjing,Chen Yawei,Shi Jing,Zhang Jieke,Liang Xinyu,Du Tianyuan
Chitosan/glycerophosphate thermosensitive hydrogel crosslinked physically was a potential drug delivery carrier; however, long gelation time limits its application. Here, chitosan-amino acid (AA) thermosensitive hydrogels were prepared from chitosan (CS), αβ-glycerophosphate (GP), and l -lysine (Lys) or l -glutamic acid (Glu). The prepared CS-Lys/GP and CS-Glu/GP hydrogel showed good thermosensitivity and could form gels in a short time. The optimal parameters of CS-Lys/GP hydrogel were that the concentration of CS-Lys was 2.5%, the ratio of CS/Lys was 3.5/1.0, the ratio of CS-Lys/GP was 4.5/1.0. The optimal parameters of CS-Glu/GP hydrogel were that the concentration of CS-Glu was 3.0%, the ratio of CS/Glu was 2.0/1.0, and the ratio of CS-Glu/GP was 4.0/1.5. Chitosan-amino acid (CS-AA) thermosensitive hydrogel had a three-dimensional network structure. The addition of model drug tinidazole (TNZ) had no obvious effect on the structure of hydrogel. The results of infrared spectroscopy showed that there were hydrogen bonds between amino acids and chitosan. In vitro release results showed that CS-Lys/GP and CS-Glu/GP thermosensitive hydrogels had sustained release effects. Thus, the chitosan-amino acid thermosensitive hydrogels hold great potential as a sustained release drug delivery system.
研究领域:
生物材料学
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药剂学
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DOI
PubMed
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2023
·
IF 6.1
Yi Wang,Hulin Li,Jingjing Zhao,Zhanguo Li,Jun Li,Jian Li
Decontamination of nuclear wastewater is of vital significance for the sustainable development of nuclear energy. Nanofiltration (NF), with the ability to realize precise ion separation, has attracted great interests in removing nuclides from the wastewater due to its high separation efficiency and easy operation feature. To fabricate NF membrane with high nuclide selectivity and excellent water perm-selectivity, chitosan (CS)-based NF membrane was synthesized in this work via a facile interfacial polymerization (IP) with polyethyleneimine (PEI) post-functionalization. The introduced PEI provided the NF membrane a strong positive charge density and a larger pore size. Consequently, high water permeance around 17.4 L m -2 h −1 bar −1 and outstanding rejections towards CoCl 2 , SrCl 2 and CsCl (94.8 %, 93.1 % and 32.3 %) were achieved. In comparison with the existing membranes, the CS-based TFC membrane possessed a higher water permeance with a similar nuclide selectivity. Moreover, the newly designed membrane sustained a high stability after treated with acid and base solutions. These features endowed the PEI functionalized chitosan-based NF membrane promising potentials in the decontamination of nuclear wastewater.
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高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Yuzhen Du,Baoying Shi,Xiayu Luan,Yufeng Wang,Haiyan Song
Storage and transportation of fresh fruits and vegetables result in significant wastage, making their preservation post-harvest a global issue. Although petroleum-based synthetic wax is commonly used in fruit post-harvest preservation due to its effectiveness, its adverse effects on ecological environment and human health cannot be ignored. Hence, it is imperative to explore natural and sustainable coatings that can serve as an eco-friendly and healthy alternative to petroleum-based synthetic waxes for fruit preservation. In this study, we developed a biocomposite coating based on chitosan (CS) as the bio-based film forming material, cellulose nanocrystals (CNC) as the reinforcement and sodium tripolyphosphate (TPP) as the crosslinking agent. By employing the dip coating process, it becomes feasible to apply micron-sized films onto the surfaces of diverse perishable fruits. The results revealed that the CNC and TPP significantly enhanced mechanical strength, oxygen barrier performance, thermal stability, antibacterial activity, and hydrophobicity of the coating. As a proof-of concept, bananas were utilized as experimental samples to investigate the impact of the coating. The findings demonstrate the efficacy of this coating in preserving the fruit's visual appeal and prolonging its storage duration. The coating can be used in various scenarios and on different products, having excellent potential in preservation technology, transportation and storage of postharvest agricultural products. The utilization of a multifunctional coating based on chitosan represents a promising and sustainable approach to address the pressing issue of global food waste. This innovative coating offers a cost-effective solution to effectively reduce postharvest losses of perishable foods, contributing to a more sustainable food system.
研究领域:
食品科学
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材料科学
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农业工程
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DOI
高影响因子
Crystals
·
2023
·Vol. 13
·期 5
·755
·
IF 2.7
Xueli Mei,Shihao Li,Yaoyao Chen,Xueli Huang,Yali Cao,Vitaliy P. Guro,Yizhao Li
The dissipation of energy in the form of heat causes a huge energy loss across the globe. Thermal insulation materials which reduce heat loss can alleviate the energy crisis. Among many thermal insulation materials, silica aerogels (SAs) have attracted extensive attention due to their high surface area, low density and low thermal conductivity. However, the applications of SAs are restricted by their mechanical fragility. In this paper, a series of different ratios of silica–chitosan composite aerogels (SCAs) were prepared by mixing sodium silicate aqueous solution and chitosan solution followed by freeze drying. The surface morphology of SAs, CAs and SCAs was studied by scanning electron microscopy (SEM). The specific surface area, pore volume and pore size of the composite aerogels were studied by N2adsorption–desorption isotherms. The thermal conductivities, chemical structures, thermal stabilities and hydrophobicities of SAs, CAs and SCAs were tested and analyzed. In addition, the adsorption properties of SCAs were measured using different organic solvents. The results reveal that when the proportion of sodium silicate aqueous solution and chitosan solution is 1:1, the obtained SCA−1/1 has the best performance, with a low thermal conductivity of 0.0369 W/m·K, a large specific surface area of 374.7 m2/g, and good thermal stability. In addition, the prepared SCAs also have good hydrophobicity and absorption properties, with adsorption capacities of 6.7–9.4 g/g, which show great application potential in the fields of insulation and adsorption.
研究领域:
材料科学
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能源工程
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环境科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Femiana Gapsari,Djarot B. Darmadi,Hans Juliano,Syarif Hidayatullah,Suteja,Sanjay Mavinkere Rangappa,Suchart Siengchin
Natural fibers are available as an essential substitute for synthetic fiber in many applications. However, the sensitivity of Chinese Windmill Palm or Trachycarpus Fortune Fiber (TFF) to water causes low interfacial bonding between the matrix and the fiber and at the end reduces the mechanical properties of the composite product. Alkaline treatment improves mechanical properties and does not affect water absorption. Hence, additional treatment in the coating is required. This study uses alkaline treatment and coating modification using blended chitosan and Acrylated Epoxidized Soybean Oil (AESO). Blend coating between AESO and chitosan is performed to increase water absorption and mechanical properties. TFF water resistance improved significantly after the coating, with water absorption of the alkaline/blend coating-TFF of 3.98 % ± 0.52 and swell ability of 3.156 % ± 0.17. This indicated that blend coating had formed a cross-link of fiber and matrix after alkalization. Thus, the single fiber tensile strength increased due to the alkaline treatment, and water absorption decreased due to the coating. The combination of alkaline treatment and blend coating on TFF brings excellent properties, as shown by the increase in tensile strength in both single fiber test and composite.
研究领域:
材料科学
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复合材料
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纤维科学
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表面化学
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DOI
PubMed
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2023
·Vol. 333
·期 1
·71-84
·
IF 1.6
Du Zhiyuan,Ni Yuran,Peng Hao,Tang Mei,Li Yuanli,Lv Lina,Li Xiaoyu,Chi Fangting
Novel chitosan crosslinked amidoxime polyacrylonitrile aerogel was synthesized and used for adsorption of uranium from seawater. The effects of initial uranium concentration, contact time, and pH value on uranium adsorption were investigated. The simulated uranium solution adsorption experiment shows that under the condition of an initial uranium concentration of 100 mg/L, the maximum adsorption capacity of CTS-g-PAO is 203.4 mg/g. The adsorption process can be well-fitted by Freundlich and Pseudo-second order models. In addition, CTS-g-PAO aerogel has good antibacterial activity against marine bacteria, with the antibacterial activity reaching 94.8%. The results demonstrated that CTS-g-PAO aerogel was an effective adsorbent for extracting uranium from seawater.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
LUMINESCENCE
·
2021
·Vol. 37
·期 1
·58-71
·
IF 2.464
Zheng Chang,Chao Zhang,Binghua Yao
A novel dual-sensitization electrochemiluminescence (ECL) immunosensor for the detection of tumour protein prostate specific antigen (PSA) at trace level using Ru(bpy) 3 2+ -doped chitosan/SiO 2 nanoparticles (Ru(bpy) 3 2+ /chitosan/SiO 2 NPs) as the first signal enhancers was fabricated. Due to chitosan with excellent pore forming capacity, these nanoparticles possess porous structures and better photopermeability, and therefore have higher luminescence efficiencies compared with Ru(bpy) 3 2+ /SiO 2 NPs reported in previous publications. Conversely, chitosan with good biocompatibility and high hydrophilicity was electrochemically decorated onto a Nafion/multiwall carbon nanotubes (Nafion/MWNTs) modified electrode surface and used as the second sensitizing matrix to seize large amounts of prostate specific capture antibody (Ab 1 ). The chitosan-decorated Nafion/MWNTs composites exhibited a 5.5-times higher ECL intensity than the unadorned Nafion/MWNTs films. Also, without additional reagents, such as (3-aminopropyl)triethoxysilane (APTS), the one-step functionalized Ru(bpy) 3 2+ /chitosan/SiO 2 NPs provided a large number of active arms to connect with PSA-detected antibodies (Ab 2 ) through the amino groups in chitosan. After a sandwich immunoreaction, the PSA antigen and Ru(bpy) 3 2+ /chitosan/SiO 2 NPs-labelled Ab 2 were sequentially captured onto the Ab 1 /chitosan/Nafion/MWNTs-modified electrode surface. The ECL signal increases were linearly related to the PSA antigen concentrations and ranged from 0.01 pg·mLl −1 to 10.0 pg·mLl −1 . Under the optimized experimental conditions, the immunosensor displayed excellent sensitivity and selectivity. The detection limit was as low as 3.4 fg·mLl −1 , equivalent to, or better than, those of the reported ECL immunosensors for PSA.
研究领域:
分析化学
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生物传感器
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纳米技术
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生物医学工程
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）