Sustainable Energy & Fuels
·
2021
·Vol. 6
·期 2
·440-448
·
IF 6.367
Xin Liang,Lulu Wang,Yang Wang,Yongchao Liu,Yi Sun,Hongfa Xiang
The functional design of separators has been proved to be one of the most efficient methods to improve the electrochemical performance of lithium–sulfur batteries. In this work, a multifunctional separator with gradual changes to four aspects was constructed by integrating a PVDF-HFP/h-BN membrane with a Co-doped carbon nanofiber. The architecture has four gradations, which offers multifold advantages. First, in terms of density, there is a transition from loose to dense, which results in a higher electrolyte uptake rate, reduces the amount of free electrolyte and further suppresses the shuttle effect. Additionally, in terms of composition, a transition from inorganic to organic is designed, which allows the inorganic and organic components to bind closely and reduces the interfacial resistance. Meanwhile, there is a transition from high electronic conductivity to insulation. The change in electronic conductivity leads to effective conversion of the polysulfide. Finally, in terms of ionic conductivity, there is a transition from low to high, which gives the separator better ability to conduct lithium ions. As a consequence, a battery with the as-constructed multifunctional separator performs with good capacity stability, which demonstrates a new concept for high-performance lithium–sulfur battery design.
研究领域:
材料科学
·
储能技术
·
电池技术
✓ 已验证
DOI
高影响因子
Frontiers in Veterinary Science
·
2025
·
IF 2.9
Qiuru Chen,Yulei Liang,Yanbin Dong,Junling Cui,Kun He,Xiaoyuan Ma,Jinfeng Zhao,Yajun Zhai,Li Yuan
H-NS is a histone-like nucleoid-structuring protein that regulates gene expressions, particularly acquired foreign genes, however, little is known about whether H-NS can modulate bacterial susceptibility by regulating its intrinsic genes. The hns-deleted mutant EΔhns, the hns-complemented strain EΔhns/phns and the hns-overexpressed strain E/phns were derivatives of Escherichia coli ATCC 25922, the susceptibility of which were assessed by the broth microdilution method and time-kill curves assays. We found that the MICs for strain EΔhns against gentamicin and amikacin were significantly decreased by 8–16 folds in contrast to E. coli ATCC 25922. Further studies displayed that the absence of hns caused damage to the bacterial outer membrane and increased the expression levels of porin-related genes, such as ompC, ompF, ompG, and ompN, thus obviously enhancing aminoglycosides uptake of strain EΔhns. Meanwhile, hns deletion also led to remarkable inhibition of the efflux pumps activity and decreased expressions of efflux-related genes clbM, acrA, acrB, acrD, and emrE, which reduced the efflux of aminoglycosides. In addition, the activation of glycolysis and electron transport chain, as well as the reduction of Δψ dissipation, could lead to a remarkable increase in proton motive force (PMF), thus further inducing more aminoglycosides uptake by strain EΔhns. Our findings reveal that H-NS regulates the resistance of E. coli to aminoglycosides by influencing its uptake and efflux, which will enrich our understanding of the mechanism by which H-NS modulates bacterial resistance.
研究领域:
微生物学
·
分子生物学
·
抗菌素耐药性
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Catalysis
·
2025
·
IF 13.1
Yu-Yang Liu,Shan Xu,Xiao-Xin Li,Run-Han Li,Xin-Ting Cai,Hui-Zhen Zhong,Jiang Liu,Qing Huang,Lei Zhang,Shun-Li Li,Ya-Qian Lan
Developing strategies and photocatalysts for C(sp3)-H bond functionalization under simple and mild conditions is important but challenging. Here, we report two redox heterocluster-based frameworks, named Ni5-PW12 and Ni5-V16, in which the terminal oxygen atoms of polyoxometalates are directly coordinated to metal atoms in metal–organic clusters. Due to the coexisting strong oxidation and reduction capacities, both of these photocatalysts achieve photocatalytic C(sp3)-H bond oxidative imination through combining oxidation of methyl aromatics and reduction of nitro aromatics reactions. The experimental and theoretical results reveal that benefiting from the short distance between the clusters, the rapid charge transfer and mass transfer processes would enhance the photocatalytic reactivity and inhibit side reactions. More importantly, all of the photocatalytic reactions are carried out in mild conditions at room temperature without any additional solvents, photosensitizers, oxidizing or reducing agents, or cocatalysts.
研究领域:
光催化
·
有机合成
·
材料化学
·
簇化学
✓ 已验证
产品关联
DOI
高影响因子
Molecular Catalysis
·
2019
·
IF 2.938
Qiaoyun Liu,Fei Liu,Yaru Zhang,Yang Su,Aiqin Wang,Tao Zhang
A highly active and robust catalyst composed of Ru nanoparticles highly dispersed on zeolite H-beta was developed for transforming furfural into 3-acetyl-1-propanol (3-AP) in good yield (81%)under mild conditions (80 °C, 1 MPa H 2 ). Both the support nature and the preparation methods had significant impacts on the dispersion of Ru, eventually on the yield of 3-AP. Ion-exchange method proved best for obtaining the highly active and selective catalyst for this reaction. Moreover, the catalyst can be regenerated easily by calcination and reduction. This catalyst was further explored for the one-pot conversion of xylose and xylan to 3-AP with a yield of 46% and 31%, respectively, thus opening a new feasible pathway from biomass to valuable fine chemicals.
研究领域:
催化化学
·
生物质转化
·
绿色化学
✓ 已验证
DOI
高影响因子
BMC Chemistry
·
2019
·Vol. 13
·期 1
·1-15
·
IF 0
Guo J.,Ma Yu L.,Yu Jia Y.,Gao Yu J.,Ma Ning X.,Wu Xiao Y.
Herein, 2-(2-methoxyphenoxy)-1-phenylethanol (β- O -4), 2-methoxyphenyl anisole (α- O -4) and 4-phenoxyphenol (4- O -5) were selected as typical lignin model compounds. Given the effectiveness of traditional acid–base catalysts for lignin depolymerisation, a novel Ni/CaO–H-ZSM-5(60) catalyst was prepared to investigate the difficulty level of C–O bond of three model compounds cleavage in ethanol. It was observed that Ni/CaO–H-ZSM-5(60) had prominent performance on the C–O bond cleavage at very mild conditions (140 °C, 1 MPa H 2 ). Among them, the C–O bond of α- O -4 and β- O -4 could be completely cleaved within 60 min. Although the C–O bond of 4- O -5 had high bond energy, 41.2% of conversion was occurred in 60 min. The introduction of CaO could regulate the acidity of H-ZSM-5 to enhance the ability to break C–O bonds. Moreover, the possible pathways of C–O ether bonds in three lignin model compounds cleavage were proposed in order to selectively obtain target products from the raw lignin degradation.
研究领域:
化学工程
·
催化科学
✓ 已验证
DOI
Journal of the American Chemical Society
·
2015
·
IF 12.113
Xiao-Li Pei,Yang Yang,Zhen Lei,Shan-Shan Chang,Zong-Jie Guan,Xian-Kai Wan,Ting-Bin Wen,Quan-Ming Wang
The activation of C(sp3)–H bonds is challenging, due to their high bond dissociation energy, low proton acidity, and highly nonpolar character. Herein we report a unique gold(I)–silver(I) oxo cluster protected by hemilabile phosphine ligands [OAu3Ag3(PPhpy2)3](BF4)4 (1), which can activate C(sp3)–H bonds under mild conditions for a broad scope of methyl ketones (RCOCH3, R = methyl, phenyl, 2-methylphenyl, 2-aminophenyl, 2-hydroxylphenyl, 2-pyridyl, 2-thiazolyl, tert-butyl, ethyl, isopropyl). Activation happens via triple deprotonation of the methyl group, leading to formation of heterometallic Au(I)–Ag(I) clusters with formula RCOCAu4Ag4(PPhpy2)4(BF4)5 (PPhpy2 = bis(2-pyridyl)phenylphosphine). Cluster 1 can be generated in situ via the reaction of [OAu3Ag(PPhpy2)3](BF4)2 with 2 equiv of AgBF4. The oxo ion and the metal centers are found to be essential in the cleavage of sp3 C–H bonds of methyl ketones. Interestingly, cluster 1 selectively activates the C–H bonds in −CH3 rather than the N–H bonds in −NH2 or the O–H bond in −OH which is traditionally thought to be more reactive than C–H bonds. Control experiments with butanone, 3-methylbutanone, and cyclopentanone as substrates show that the auration of the C–H bond of the terminal methyl group is preferred over secondary or tertiary sp3 C–H bonds; in other words, the C–H bond activation is influenced by steric effect. This work highlights the powerful reactivity of metal clusters toward C–H activation and sheds new light on gold(I)-mediated catalysis.
研究领域:
无机化学
·
有机金属化学
·
催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Energy Chemistry
·
2023
·
IF 13.1
Yuzhu Qian,Hongrui Wang,Xinni Li,Ting Song,Yong Pei,Li Liu,Bei Long,Xiongwei Wu,Xianyou Wang
The development of insertion-type anodes is the key to designing “rocking chair” zinc-ion batteries. However, there is rare report on high mass loading anode with high performances. Here, {001}-oriented BiOCl nanosheets with Sn doping are proposed as a promising insertion-type anode. The designs of cross-linked CNTs conductive network, {001}-oriented nanosheet , and Sn doping significantly enhance ion/electron transport, proved via experimental tests and theoretical calculations (density of states and diffusion barrier). The H + /Zn 2+ synergistic co-insertion mechanism is proved via ex situ XRD, Raman, XPS, and SEM tests. Accordingly, this optimized electrode delivers a high reversible capacity of 194 mA h g −1 at 0.1 A g −1 with a voltage of ≈0.37 V and an impressive cyclability with 128 mA h g −1 over 2500 cycles at 1 A g −1 . It also shows satisfactory performances at an ultrahigh mass loading of 10 mg cm −2 . Moreover, the Sn-BiOCl//MnO 2 full cell displays a reversible capacity of 85 mA h g −1 at 0.2 A g −1 during cyclic test.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2017
·
IF 3.887
Zhili Deng,Menghuan Tang,Li Zhao,Yijuan Long,Zuhuang Wen,Yuan Cheng,Huzhi Zheng
A novel targeting drug delivery system for cancer therapy based on H + -triggered bubble-generating nanosystems (BGNSs) was engineered. First, hollow mesoporous silica nanoparticles (HMSNs) were used to load doxorubicin (DOX). Then, the obtained drug-loaded HMSNs were treated with NaHCO 3 to prepare the BGNSs. The BGNSs were coated with polydopamine (pDA), and finally, folic acids (FA) were anchored on the nanosystems to obtain the desired nanoscale drug delivery system ( [email protected] ). [email protected] was effectively internalized by cancer cells through folate receptor-mediated endocytosis and generated CO 2 bubbles under the acidic environment of the lysosomes, thus enhancing lysosomal membrane permeability (LMP) to release caspase-3 into the cytoplasm, resulting in cancer cell death via an apoptosis-like pathway. Notably, we demonstrated that the [email protected] exhibited a significant simultaneous synergetic cytotoxicity against MCF-7 cells and remarkably overcame the multidrug resistance (MDR) of MCF-7/ADR cells. Moreover, compared to free DOX and a nanosystem without FA modification (BGNSs), the [email protected] induced relatively minor side effects in the MCF-10A cells. Therefore, the results showed that [email protected] , as a targeted drug delivery system, have a good probability of overcoming the MDR of tumor cells with minor side effects on normal cells.
研究领域:
纳米技术
·
药物科学
·
癌症研究
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2021
·
IF 5.706
Mingyang Tan,Liang Zhu,Hao Liu,Yajun Fu,Shuang-Feng Yin,Weijun Yang
A Cobalt porphyrin conjugated porous polymer (Co/PCP) was obtained by hybrid polymerization of a mixture of Co(II)(5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphyrin) (CoTBPP) and 5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphyrin (TBPP) (3:7 M ratio) with the coupling reagent of p-phenyldiboric acid. This Co/PCP was carbonized at 400 °C and the obtained catalyst (denoted as Co 3 O 4 @PNC-400) was composed of Co 3 O 4 nanoclusters wrapped in the nitrogen-carbon materials. This catalyst has an extremely high catalytic activity for the aerobic oxidation of C–H bonds. It can efficiently catalyze the oxidation of the C–H bonds in toluene and cyclohexane with high conversion and high selectivity of (alcohol + aldehyde), (alcohol + ketone) compounds, respectively. When heat-treated at 400 °C, the porous framework structure of the porphyrin polymer was partially retained, and the highly active Co 3 O 4 nanoclusters were generated in situ. The reaction of C N to C N and connection with the Co 3 O 4 nanoclusters also occurred. Co 3 O 4 @PNC-400 has obvious synergistic catalytic effect between Co 3 O 4 and nitrogen-carbon framework during the catalytic reaction. The defective structure caused by the migration of cobalt also greatly improved the catalytic activity. Co/PCPs with different cobalt contents were also synthesized and heat treated at different temperature. These catalysts were a new type of efficient C–H oxidation catalysts with excellent potential application value.
研究领域:
材料科学
·
催化
·
化学工程
·
有机化学
✓ 已验证
DOI
高影响因子
Journal of Energy Storage
·
2024
·
IF 8.9
Wei-Xiang Cheng,Ting-Ting Mao,Yi-Zhao Chen,Shuai-Fu Cui,Jing Chen,Dao-Ren Deng,Ru-Ming Feng,Song-Yi Liao,Yong-Gang Min
In this paper, cubic ZnSn(OH) 6 with MXene were firstly in-situ synthesized, and subsequently vulcanized and etched to obtain hollow SnS nanoboxes with MXene coating by carbon layer (referred to as H-SnS/MXene@C). The composition and surface chemical state of H-SnS/MXene@C were characterized by XRD and XPS , respectively. The microscopic morphology of H-SnS/MXene@C was analyzed and characterized in detail by SEM and TEM, and the results show that the hollow SnS nano-boxes formed an effective connection with the MXene nanosheets . When used as LIBs anode, the H-SnS/MXene@C maintained ∼707 mAh/g after 200 cycles at 0.5 A/g current density. As a NIBs anode material, the H-SnS/MXene@C delivered ∼402 mAh/g after 150 cycles at 0.5 A/g current density. In addition, a detail simulation/calculation revealed that H-SnS/MXene@C demonstrated a higher pseudocapacitance (83.2 % for LIBs and 74.4 % for NIBs at a scan rate of 2 mV/s, respectively). The synergistic effect of the highly conductive MXene and the three-dimensional hollow cubic structure could effectively provide an efficient channel for charge transfer and ionic diffusion in H-SnS/MXene@C anode.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ji Shu,Yichong Zhang,Kanming Wang,Jianli Wang,Jiaxuan Ying,Hongyu Wang
Membrane filtration is regarded as one of the promising technologies for water treatment. However, insufficient micropollutants removal and membrane fouling still limited the further application. Herein, this study engineered a novel membrane hybrid system integrating typical pharmaceuticals removal and membrane self-cleaning by assembled layered MXene and hexagonal boron nitride (h-BN). By doping a small amount of MXene into h-BN (mass ratio of 1 to 10), the synergetic process of adsorption and photocatalytic degradation were achieved. Based on experimental and density functional theory (DFT) calculation results, the chemisorption-photodegradation performance of the membrane hybrid system assembled with 1/10 MXene@h-BN was significantly enhanced due to the termination group and conductive property of MXene. In addition, trimethoprim (TMP) degradation by the above membrane followed the Langmuir–Hinshelwood model, indicating pollutants removal initiated not only on the membrane surface but also in the bulk solution under simulated solar irradiation. This phenomenon was attributed to the generation of •OH and 1 O 2 by forming Ohmic contact with altered internal band structure. The durability and practical experiments with secondary effluent from local wastewater treatment were also tested. The exceptional self-cleaning performance of the membrane hybrid system assembled with 1/10 MXene@h-BN was demonstrated by lower membrane fouling and maintaining durability even after five cycles. Furthermore, the performance (both pollutants removal and flux) of the modified membrane for secondary effluent treatment was also considerable, validating its potential for practical application. Owing to the excellent features, the membrane assembled with MXene@h-BN is anticipated to be an ideal candidate for advanced wastewater treatment.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2025
·
IF 3.6
Yang Zhu,Guisheng Deng
The I2-catalyzed reaction of 1-(2-hydroxyphenyl)-propargyl alcohols with indoles and subsequent treatment with K2CO3 provided (benzofuran-3-yl)-1H-indoles in good to excellent yields with high regioselectivity. This one-pot and two-step strategy proved to be suitable for a wide range of substrates except for aliphatic alkynyl alcohols as well as the indoles bearing N-protected groups such as the Ts group possessing strong electron-withdrawing feature. The reaction procedure involved a cross-coupling and the construction of a benzofuran framework via 5-exo-dig cyclization.
研究领域:
有机化学
·
合成化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）