INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Ju Liu,Danna Yan,Qianying Chen,Huayong Peng,Lu Jin,Chong Feng,Lixia Zhang,Guomin Zhao,Depo Yang,Zhimin Zhao
In this study, a homogeneous polysaccharide, named YDOP-1 was isolated form Dendrobium officinale using hot water extraction and ethanol precipitation method. YDOP-1 was characterized to be a typical O -acetyl-glucomannan with the molecular wight was 13,456 Da. Cell viability and colony forming assay showed that YDOP-1 possess moderate anti-gastric cancer effects. In order to further improve the anti-gastric cancer effects of YDOP-1, a selenium modification on YDOP-1 was performed. Energy dispersive spectrometer (EDS) and X-ray photoelectron spectroscopy (XPS) analysis demonstrated that the Se was successfully introduced into YDOP-1 by forming Se O bonds. Se modification significantly enhanced the anti-gastric cancer effects of YDOP-1, which could effectively inhibit the proliferation of MGC-803 cells via suppressing colony and inducing apoptosis by regulating the apoptosis proteins of Bax, Bcl-2, and Caspase-7. Our results indicated that the Se modified O -acetyl-glucomannan, YDOP-Se, was expected to be useful in the biomedicine field for the gastric cancer treatment.
研究领域:
药用植物学
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肿瘤生物学
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生物医学工程
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DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2017
·Vol. 409
·期 10
·2531-2537
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IF 3.431
Cheng Hao,Wu Shubin,Huang Jinbao,Zhang Xiaohua
Although o -quinonemethide (6-methylene-2,4-cyclohexadien-1-one) has been proposed as a key intermediate in char formation during the pyrolysis of guaiacol (2-methoxyphenol), direct evidence of this (e.g., spectroscopic data) has not yet been provided. Using in situ FTIR spectroscopy, the pyrolysis of guaiacol was investigated from 30 °C to 630 °C at 40 °C/min. The IR profiles showed direct evidence of o -quinonemethide production at about 350 °C, which vanished rapidly at around 420 °C in the vapor phase, indicating char formation. In addition, at 400 °C, salicyl aldehyde was observed, which decomposed slowly at about 500 °C. In combination with the known products of guaiacol pyrolysis, these results allowed the major reaction pathways of guaiacol pyrolysis to be discerned. Density functional theory calculations were performed, and the results were found to be in good agreement with the experimentally obtained IR profiles. These findings provide guidance on how to suppress secondary reactions of guaiacol during lignin pyrolysis.
On-line analysis of pyrolysis process of guaiacol using in situ FTIR
研究领域:
化学
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材料科学
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能源科学
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
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2018
·Vol. 42
·期 21
·17644-17651
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IF 3.201
Shaobo Li,Tao Zhu,Lichun Dong,Mingdong Dong
Heteroatom doping has been demonstrated to be an effective way to tune the properties of nanomaterials including chemical reactivity and electronic and optical performance. In this study, rGO/g-C3N4 and boron doped rGO/g-C3N4 (B-rGO/g-C3N4) nanocomposites were fabricated via a rapid plasma treatment method, and their photocatalytic performance under visible light radiation was examined. The results showed that the photocatalytic efficiency of B-rGO/g-C3N4 for rhodamine B degradation can be 50% higher than that of rGO/g-C3N4 at an optimum rGO loading of 5 wt%. XPS and FTIR analyses indicated the enhanced C–O–C covalent bonding between rGO and g-C3N4 in B-rGO/g-C3N4, and the optical characterization demonstrated that it could further improve the separation of the photo-generated chargers and narrow the bandgap of the nanocomposite. This work provides an idea that boron doping could be an effective way to promote the chemical interaction between different components in composite materials, which is important in designing and developing new functional nanomaterials.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2021
·
IF 19.503
Shenghua Ye,Yaqi Lei,Tingting Xu,Lirong Zheng,Zhida Chen,Xiuyuan Yang,Xiangzhong Ren,Yongliang Li,Qianling Zhang,Jianhong Liu
In this study, phosphate FeCo(H 3 O)(PO 4 ) 2 nanosheet arrays (NAs) were synthesized using an electrochemical strategy. FeCo(H 3 O)(PO 4 ) 2 NAs as precatalyst could undergo significant self-reconstruction, including leaching of phosphate anions and electro-oxidation of Co 2+ during anodizing at the potential range of oxygen evolution reaction (OER) in 1 M KOH solution, eventually resulting in the formation of Fe 0.5 Co 0.5 OOH NAs with low crystallinity . The high content of Fe in Fe 0.5 Co 0.5 OOH NAs promoted the formation of active Fe 3+ –O–Fe 3+ motifs that increased OER occurrence. Additionally, Fe incorporation increased the ratio of the reaction rate constants of oxygen evolution to Co 3+ /Co 4+ (k OER /k M,ox ) and enhanced the reaction order on the hydroxyl ion . These factors significantly contributed to the outstanding OER catalytic performances of Fe 0.5 Co 0.5 OOH NAs.
研究领域:
材料科学
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电化学
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DOI
高影响因子
Current Drug Delivery
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2018
·Vol. 15
·期 4
·585-593
·
IF 2.078
Su Qin,Pu Ximing,Bai He,Chen Xianchun,Liao Xiaoming,Huang Zhongbing,Yin Guangfu
Background: Liposomes have been widely used in gene transfection and drug delivery systems due to their excellent biocompatibility and encapsulation ability, especially, the ability to deliver the gene/drug into the cells via the membrane fusion. Thermosensitive liposomes have
been proven to be a precise and effective method for cancer treatment in many preclinical studies. But the imperfect crystalline arrangement between grains occurred, resulting in planar defects at the boundaries of membranes, compromising the stability of thermosensitive liposomes. Objective:
In the present study, we developed a facile method to improve the stability of ordinary thermosensitive liposomes by introducing organic-inorganic hybrid materials with local Si-O-Si net. Method: A cerasome forming lipid, N, N-Dihxadecyl-N'- [(3-triethoxysilyl) propyl] urea, was synthesized
and then introduced into the thermosensitive lipids to form the composite liposomes (named as cera-liposomes). The effects of the cerasome forming lipid on the cera-liposomes characteristics, including the morphology, drug loading, Zeta potential and stability of vesicles, were investigated.
Results: Cera-liposomes were thermosensitive, and they had a loading efficiency over 2 folds more than conventional thermosensitive liposomes. With the enhanced sustain of Si-O-Si, cera-liposomes were able to avoid collapsing and fusing during storage, and had a good resistance to nonionic
surfactant. More than 80% drug was still retained after storage of 15 days at room temperature. Conclusion: The cerasome forming lipid showed potential in improving the stability of thermosensitive liposomes. This novel kind of cera-liposomes could be a stable and effective drug carrier
for anticancer applications.
研究领域:
药剂学
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生物材料学
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肿瘤治疗
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
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2018
·
IF 3.057
Hanqin Liang,Huilu Guo,Jinwei Yin,Kaihui Zuo,Yongfeng Xia,Dongxu Yao,Jian Zhang,Yuping Zeng,Shiwei Wang
Transparent AlON ceramics were bonded with Lu-Al-Si-O-N oxynitride glass interlayer at 1450 °C in nitrogen atmosphere in this investigation. The Lu-Al-Si-O-N oxynitride glass showed good wettability on the AlON substrate and had strong interface adhesion with each other. The joining process had no detrimental effect on the in-line transmittance of transparent AlON ceramics but caused slight decrease of flexural strength due to the partial decomposition. The bonding strength of AlON/AlON joint was 142.7 ± 6.3 MPa at room temperature and 110.1 ± 9.6 MPa at 1200 °C in situ, which were comparable with those of the parent AlON ceramics. Some Lu 2 Si 2 O 7 grains crystallized out from the glass interlayer after joining.
研究领域:
材料科学
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陶瓷工程
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DOI
高影响因子
ACS Applied Materials & Interfaces
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2021
·
IF 9.229
Wenwei Lin,Wen-Ti Guo,Liquan Yao,Jianmin Li,Limei Lin,Jian-Min Zhang,Shuiyuan Chen,Guilin Chen
Hydrothermal deposition is emerging as a highly potential route for antimony-based solar cells, in which the Sb2(S,Se)3 is typically in situ grown on a common toxic CdS buffer layer. The narrow band gap of CdS causes a considerable absorption in the short-wavelength region and then lowers the current density of the device. Herein, TiO2 is first evaluated as an alternative Cd-free buffer layer for hydrothermally derived Sb2S3 solar cells. But it suffers from a severely inhomogeneous Sb2S3 coverage, which is effectively eliminated by inserting a Zn(O,S) layer. The surface atom of sulfur in Zn(O,S) uniquely provides a chemical bridge to enable the quasi-epitaxial deposition of Sb2S3 thin film, confirming by both morphology and binding energy analysis using DFT. Then the results of the first-principles calculations also show that Zn(O,S)/Sb2S3 has a more stable structure than TiO2/Sb2S3. The resultant perfect Zn(O,S)/Sb2S3 junction, with a suitable band alignment and excellent interface contact, delivers a remarkably enhanced JSC and VOC for Sb2S3 solar cells. The device efficiency with the TiO2/Zn(O,S) buffer layer boosts from 0.54% to 3.70% compared with the counterpart of TiO2, which has a champion efficiency of Cd-free Sb2S3 solar cells with a structure of ITO/TiO2/Zn(O,S)/Sb2S3/Carbon/Ag by in situ hydrothermal deposition. This work provides a guideline for the hydrothermal deposition of antimony-based films upon a nontoxic buffer layer.
研究领域:
材料科学
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太阳能
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半导体物理
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DOI
PubMed
高影响因子
TETRAHEDRON
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2015
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IF 2.641
Juyou Lu,Hong Wan,Yunna Xue,Yongmei Du,Jian Lu
A convenient and efficient Ni-catalyzed reaction has been developed for synthesis of mono-substituted o -carboranes, involving cross-coupling of readily available and sterically hindered 1-bromomethyl- o -carborane with various alkyl and aryl Grignard reagents under mild conditions, and the corresponding o -carborane derivatives were obtained in good to excellent yields. This method should provide a new strategy for construction of diverse and useful functionalized boron cluster compounds for medicinal chemistry and material chemistry.
研究领域:
有机化学
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材料化学
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药物化学
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DOI
高影响因子
DYES AND PIGMENTS
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2018
·
IF 3.767
Xueyan Wu,Jixi Guo,Jianzhang Zhao,Yuanyuan Che,Dianzeng Jia,Yi Chen
The development of organic single-molecule multiple photoluminescence compounds hold a great promise for advanced opt-electronic devices, optical probes and temperature sensors . The pyrenyl-substituted o -carborane, CSP and CDP , were obtained via a modified nickel-catalyzed cross-coupling reaction in satisfactory yields. Based on variety of spectroscopic measurements, it was found that the CSP and CDP exhibit multifunctional luminescent properties, such as dual emissions as well as thermochromic luminescence between orange and blue for CSP , ternary species emissions for CDP , and aggregation induced emission (AIE) and AIE enhancements (AIEE) properties for both. The origination of the multiple photoluminescence attributes was investigated deeply. We demonstrated that the multiple photoluminescence in the pyrenyl-substituted o -carborane rose from the electronic interaction between pyrenyl and o -carboranyl leading to the formation of ICT state, and the mono-molecular excimer emission attributed to the interaction between the conformational of two “face−to−face” pyrene chromophores . In addition, clear thermochromic luminescence properties were caused by ICT at room temperature and excimer formation at 77 K in the solid state. The results are useful as a guideline for designing luminescent solid materials with multiple photoluminescence and thermochromic luminescence properties.
研究领域:
材料科学
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光化学
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有机化学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jiawen Zhang,Haoyang Xu,Yage Zheng,Yue Shen,Chaoqun Mu,Yao Wang,Aili Niyazi,Zhixian He,Zhiqiang Zhang,Liang Zhang,Juanqin Xue
In this work, a Z -scheme heterostructured BiOCOOH/O-gC 3 N 4 material was synthesized and immobilized on chitosan (CTS) to obtain the BiOCOOH/O-gC 3 N 4 /CTS photocatalytic material for photocatalytic degradation of oxytetracycline hydrochloride (CTC).Our findings indicate that the composite material BiOCOOH/O-gC 3 N 4 , as well as the BiOCOOH/O-gC 3 N 4 /CTS composite membrane , displayed a significantly higher efficiency in photocatalytic degradation of CTC compared to BiOCOOH alone, owing to the synergistic effect of adsorption and photocatalysis . Following four cycles of use, the composite material retained around 96 % of its initial photocatalytic degradation activity. The addition of CTS in the photocatalytic material resolved issues such as aggregation and difficult recovery commonly encountered with powder materials, thereby facilitating effective collision between the photocatalytic active sites and CTC. Experimental and theoretical calculations provided confirmation that the combination of BiOCOOH and O-gC 3 N 4 effectively enhanced the light absorption capacity and photocatalytic performance. Furthermore, we investigated the influence of environmental factors such as pH value and anions on the photocatalytic degradation experiment, which offers valuable insights for the application of composite catalysts in wastewater treatment .
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Sheng Zhong,Bin He,Shuang Wei,Ruirui Wang,Ruirui Zhang,Ruixia Liu
Electrocatalytic glycerol oxidation reaction to produce high-value organic chemicals has research significance for managing the overproduction of glycerol and handling the energy crisis. Herein, a copper-based self-supporting catalytic electrode with a dynamic Fe-O-Cu optimized coordination (Fe-CuO x /CF) was prepared. The oxygen-bridged asymmetric coordination structure (Fe-O-Cu) optimized the electronic configuration and promoted the formation of the crucial intermediate species. After Fe was embedded in the lattice of copper oxides, a remarkable enhancement in the adsorption capacity of OH - and glycerol was confirmed. As a result, Fe-CuO x /CF exhibited an excellent production capacity of formate, with high faradaic efficiency and selectivity values of 93.65 % and 95.10 %. Concurrent production of formate and high purity hydrogen was achieved in the double-electrode flow electrolyzer. This work provides guiding significance for the optimization of the catalytic coordination and the design of high-efficiency transition metal-based catalysts for electrooxidation of biomass platform molecules.
研究领域:
电化学
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催化材料
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能源化学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hongxi Zhang,Zhongke Li,Xiande Yang,Meng Li,Liang Wei,Jing Yang
Lignin is anticipated to serve as a replacement for dwindling fossil fuel resources owing to its abundant sources and renewable nature. The electrochemical oxidation technique for depolymerizing lignin has garnered significant interest for its environmentally friendly and mild operating conditions. Nevertheless, the current utilization of auxiliary electrolytes, predominantly organic bases, ionic liquids, and other specialized substances, poses a constraint on the widespread adoption of this approach. Furthermore, there is a scarcity of instances where electrochemical technology has been employed to depolymerize the α-O-4 bond in lignin for the production of highly selective acetals. In this study, a sodium chloride/methanol (NaCl/MeOH) system was utilized for the direct depolymerization of the α-O-4 bond in a lignin model molecule, specifically benzyl phenyl ether (BPE). The optimal conditions resulted in a 95.2 % conversion rate of the BPE substrate and a high yield of 94.5 % for the main product, benzaldehyde dimethyl acetal(Bda). This research offers a promising approach for the electrocatalytic depolymerization of α-O-4 bonds in lignin, leading to the selective production of acetal chemicals using a common auxiliary electrolyte at room temperature in just 2 h.
研究领域:
化学工程
·
可再生资源技术
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）