ACS Sustainable Chemistry & Engineering
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2020
·
IF 7.632
Zhiyan He,Guangxing Yang,Hongjuan Wang,Fengying Dai,Feng Peng,Hao Yu
Metal- and nitrogen-doped carbon materials (Me–N–C) have received intensive scientific interest as single-atom catalysts (SACs) for electro- and thermocatalytic reactions. In this work, the potential of Me–N–C (Me = Co, Fe, Ni)-wrapped carbon nanotubes (CNTs) as support of platinum nanoparticles (Pt NPs) for base-free oxidation of glycerol was investigated. Co-doping of transition metal and nitrogen significantly enhanced the dispersion of Pt, indicating the advantages of the supporting material for noble-metal catalysts. Two-fold improvement of turnover of glycerol was observed over 5Pt/CoNC@CNT compared to 5Pt/CNT under the same reaction conditions. A kinetics study was conducted to understand the role of CoNC as a support of Pt NPs in a wide range of oxygen partial pressure from 0.04 to 0.4 MPa and a range of glycerol concentration from 0.012 to 0.15 wt %. A synergistic effect between Me–N–C, especially Co–N–C, and Pt NPs was revealed. The Co–N–C support facilitated the activation of oxygen and thus enhanced the overall turnover of glycerol oxidation, especially at high glycerol concentrations. This finding suggests a new approach to the high-performance Pt catalysts via introducing SACs as supporting materials that afford auxiliary active sites for the target reaction.
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NEW JOURNAL OF CHEMISTRY
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2020
·Vol. 44
·期 48
·21085-21091
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IF 3.288
Hongli Zhu,Jing Huang,Huijun Chen,Xiaomiao Feng
In recent years, self-propelled micromotors have attracted great attention due to their intelligent properties. To obtain a bubble-propelled micromotor, additional catalysts are required, which are usually expensive, toxic, and unstable, and lead to uncontrolled motion. To overcome these limits, ZIF-67, as a kind of MOF material, was chosen as a micromotor precursor; porous carbon decorated with magnetic Co nanocomposites (Co@PCs) could be obtained via an annealing process involving ZIF-67. These Co@PCs were used as micromotors for drug delivery, and were mass-producible, stable, and biocompatible. Due to the presence of magnetic Co, their motion could be controlled in a magnetic field. Co@PCs carbonized at 600 °C were self-propelled at a speed of 27.68 μm s−1, which corresponded to a relative speed of about 7.92 body-lengths s−1 at a fuel concentration of 5% with a lifetime of about 60 minutes. Furthermore, Co@PCs could be used as nanocarriers for the loading and release of the anticancer drug doxorubicin.
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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2020
·Vol. 104
·期 23
·10005-10018
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IF 3.53
Guo Xiaolei,Wu Weibin,Zhang Mingliang,Wu Licheng,Huang Jianzhong
Abstract l -Tyrosine is a versatile compound used in the fine chemical, pharmaceutical, and functional food industries. Here, we report a bi-enzymatic cascade involving alanine racemase (ALR) and d -amino acid oxidase (DAAO) to produce pyruvate, as co-substrate for l -tyrosine production, from the cheap substrate l -alanine. The BpALR (ALR from Bacillus pseudofirmus ) was used as a whole-cell biocatalyst, converting l -alanine to d , l -alanine. The FsDAAO (DAAO from Fusarium solani ) was immobilized to oxidize the d -alanine generated in the first step to pyruvate. Both systems were combined as a continuous-flow reactor for maximized l -alanine-to-pyruvate conversion rates. The optimal parameters and appropriate conditions for FsDAAO immobilization were investigated. The pyruvate concentration of 86.6 g/L was achieved within 17 h. Subsequently, a whole-cell biocatalyst system for l -tyrosine production, catalyzed by the tyrosine phenol-lyase (TPL) from Erwinia herbicola (EhTPL), was developed, and a fed-batch approach was applied with phenol and the pyruvate produced with the ALR/DAAO system mentioned above. The concentration of phenol and pyruvate in the reactor should not exceed 7.5 g/L and 10 g/L, respectively. Significantly, the l -tyrosine concentration of 152.5 g/L was achieved within 10 h, demonstrating the great potential for high-efficiency production of l -tyrosine through the approach we established in this paper. Graphical abstract Key points • A specific bioreactor system for pyruvate produced from l -alanine was developed • The appropriate condition for immobilization of FsDAAO was investigated • A fed-batch process was established to produce l -tyrosine with recombinant E. coli • The bi-enzymatic cascade was successfully used for l -tyrosine production at low cost
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高影响因子
POLYMER TESTING
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2020
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IF 3.275
Meizhou Sun,Heling Guo,Jiliang Zheng,Yu Wang,Xinghuan Liu,Qian Li,Rongjie Wang,Xin Jia
Polymer coated fertilizer has been designed for gradual release of nutritional content of fertilizer to improve the utilization efficiency. However, the better slow release property of the coated fertilizer and simplified preparation process are still a huge challenge. The hydrophobic ODA-polyphenol film coated urea was prepared by one-step spraying for excellent nutrient release performance. Octadecylamine (ODA) was used to modify poly(tannic acid) (PTA) and poly(pyrogallol) (PPG) coating on substrates and prepare the hydrophobic ODA-PTA and ODA-PPG coated urea granules. The nutrient release rate of ODA-PTA and ODA-PPG coated fertilizers was much slower than PTA and PPG coated fertilizers in water and soil. The N release longevities of ODA-PTA coated fertilizers will be extended from 2 h to 30 days compared with PTA coated fertilizers. Moreover, pot experiments showed that coated fertilizer could effectively promote plant growth. This work will provide one-step spraying co-deposition approach to fabricate hydrophobic ODA-polyphenol film coated urea to improve the N release longevity, which can shine a light on the development of new slow release fertilizers (SRFs).
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MATERIALS & DESIGN
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2020
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IF 6.289
Guoyong Wang,Guowen Qian,Jun Zan,Fangwei Qi,Zhengyu Zhao,Wengjing Yang,Shuping Peng,Cijun Shuai
Poly l-lactic acid (PLLA) was limited in the further orthopaedic application due to its insufficient mechanical property and poor bioactivity. Graphene oxide (GO) is an effective reinforcement, whereas silicon-doped hydroxyapatite (Si-HA) possesses excellent bioactivity, but either GO or Si-HA tends to aggregate in PLLA matrix. In this study, a [email protected] nanosystem was achieved by in-situ growth of Si-HA on GO, and then incorporated into PLLA scaffold fabricated by laser sintering technology. On one hand, Si-HA on the surface of GO effectively prevented the aggregation of GO by acting as a barrier between GO nanosheets. On the other hand, GO hindered the aggregation of Si-HA by means of anchoring Si-HA. Results displayed that the compressive strength and modulus of the PLLA/ [email protected] composite scaffold were enhanced by 85% and 120%, respectively. Meanwhile, the scaffold exhibited significantly improved bioactivity, and consequently promoted cell adhesion, proliferation and differentiation. The developed PLLA/ [email protected] composite scaffold with excellent mechanical properties and superior bioactivity could serve as a promising substitute for bone repairing.
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ChemElectroChem
·
2020
·Vol. 7
·期 15
·3311-3318
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IF 4.154
Jianfa Chen,Chong Lin,Mengmeng Zhang,Tianxiang Jin,Yong Qian
Graphical Double doping : We develop a simple and efficient method to prepare N and Se co-doped graphene aerogel (NSeGA) as binder-free electrodes for supercapacitor applications. The results proved that Se is an efficient doping element for carbon-based materials. Furthermore, benefiting from the synergistic effect between N and Se, the NSeGA electrode shows a high specific capacity of 302.9 F g −1 at 1 A g −1 , and a high capacity retention of >94 % after 12,000 cycles. In this work, we demonstrate the successful synthesis of nitrogen and selenium co-doping graphene aerogels (NSeGA) by a convenient and scalable approach. It was found that Se is an effective doping element for improving the energy storage performance of graphene. The synergistic effect between N and Se on improving the performance of supercapacitor was also confirmed. The binder-free NSeGA electrode exhibited a high specific capacity of 302.9 F g −1 at a current density of 1 A g −1 , which is much higher than that of singly Se-doped graphene aerogel (SeGA, 183.92 F g −1 ) and singly N-doped graphene aerogel (NGA, 150.16 F g −1 ). Even though the current density reached up to 10 A g −1 , 90.4 % of its specific capacitance was maintained. The NSeGA also maintained about 94.1 % of the initial capacitance after 12,000 cycles at a current density of 2 A g −1 . Moreover, the constructed NSeGA//NSeGA symmetric supercapacitor showed a high energy density of 26.3 W h kg −1 at a power density of 900 W kg −1 . Accordingly, as a new type of carbon-based material, NSeGA has a good prospect in the field of supercapacitors.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2020
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IF 4.939
Xuezhen Zhu,Haisheng Tao,Maoguo Li
Prussian blue analogue with a typical metal-organic framework has been widely used as an electrode material in supercapacitor . In this work, nickel cobalt hexacyanoferrate (Ni 2 CoHCF) was grown on nickel foam directly using a simple co-precipitation method. The as-prepared Ni 2 CoHCF was tested by transmission electron microscope, scanning electron microscope , X-ray diffraction and X-ray electron energy spectrum. The results showed that Ni 2 CoHCF has a unique open face-centered cubic structure. The Ni 2 CoHCF was used to set an asymmetric supercapacitor directly. A series of electrochemical tests showed that Ni 2 CoHCF had an excellent electrochemical performance. The specific capacitance of the supercapacitor was 585 C g −1 (1300.0 F g −1 , 162.5 mAh g −1 ) at the current density of 0.5 A g −1 . After 2000 cycles, it still maintained 85.57% of its initial specific capacitance at the current density of 10 A g −1 . The energy density was 30.59 Wh kg −1 at the power density of 378.7 W kg −1 . The results show that the supercapacitor constructed by Ni 2 CoHCF as an electrode material has high-current charge-discharge capacity, high energy density and long cycle life.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2020
·Vol. 27
·期 18
·22806-22817
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IF 3.056
Li Jie,Yu Guangwei,Pan Lanjia,Li Chunxing,You Futian,Wang Yin
Antibiotics residues in aqueous environment and sewage sludge accumulation have become serious environmental issues. The aim of this study is to investigate the potential of ciprofloxacin (CIP) removal by sludge-based biochar prepared from co-pyrolysis of sewage sludge and bamboo waste (BW). The stability and environmental risk of heavy metals (HMs) in the biochar were further investigated to evaluate potential risks for biochar utilization. Results showed that BW was an outstanding additive to prepare co-pyrolyzed biochar from sludge. A higher CIP removal rate (95%) of BW-sludge biochar (SBC) was obtained under initial CIP concentration of 10 mg/L, and its maximum adsorption capacity was 62.48 mg/g which was calculated from the Langmuir model. The pseudo-second-order and Freundlich model also well fit the CIP adsorption process, indicating a chemical and multilayer adsorption of CIP on a heterogeneous surface of biochar. Adsorption mechanism analysis indicated that the diverse functional groups and Fe species in biochar probably were the dominant factors in the adsorption of CIP. The π-π interaction, H–bond, ion exchange, and Fe-complexation might be the main interactions between the functional species and CIP molecules. Besides, HMs, especially the Cr, Cd, and As, were well immobilized in SBC compared with pure sludge biochar. This work suggested that sludge-based biochar, especially the co-pyrolyzed SBC, could be a potential adsorbent for CIP removal from aqueous solutions.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 25
·10739-10746
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IF 3.288
Xuecheng Liu,Linjie Yan,Linxin He,Zurun Yao,Linfeng You,Lin Liu,Guilin Zhou,Hongyu Huang
The Co–C3N4/BiPO4 photocatalyst is facilely synthesized for application in photocatalytic water splitting. The physical and chemical properties of Co–C3N4/BiPO4 are studied by a wide range of characterization methods. The Co–CN/BP photocatalyst shows good photocatalytic activity for H2 evolution by water splitting without using a noble metal. The Co–C3N4/BiPO4 composite with 5 wt% Co–C3N4 loading exhibits a superior photocatalytic H2 evolution rate of 23.9 μmol h−1 g−1. The remarkable enhancement of the photocatalytic H2 evolution activity of Co–C3N4/BiPO4 composites is mainly ascribed to the effective charge transfer and separation of the electron–hole pairs by the lattice-matched heterojunction structure. This work extends opportunities for the design of non-noble metal photocatalysts with efficient photocatalytic water splitting.
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高影响因子
APPLIED SURFACE SCIENCE
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2020
·
IF 6.182
Fangxu Dai,Ying Wang,Xinran Zhou,Ruiyang Zhao,Jishu Han,Lei Wang
An efficient visible light responsive ZnIn 2 S 4 @NH 2 -MIL-53(Fe/Co 0.75 ) nanocomposite was prepared for photocatalytic hydrogen production application. Under visible light irradiation, the ZnIn 2 S 4 @NH 2 -MIL-53(Fe/Co 0.75 ) photocatalyst displayed improved photocatalytic performance and the hydrogen production rate reached to 161724.8 μmol/g in 6 h. The nanocomposite with large specific surface area and mesoporous structure increased the light absorption, improved the electrons transfer and suppressed the recombination of photogenerated electron-hole pairs, thus exhibiting efficient photocatalytic hydrogen production performance. The controllable synthesis of ZnIn 2 S 4 @NH 2 -MIL-53(Fe/Co 0.75 ) nanocomposite as a high-efficiency photocatalyst would have broad prospect for water splitting hydrogen production application.
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TOXICOLOGY AND APPLIED PHARMACOLOGY
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2020
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IF 3.347
Cong Zhang,Lei Sheng,Ming Yuan,Junjie Hu,Yan Meng,Yong Wu,Liang Chen,Huifan Yu,Shan Li,Guohua Zheng,Zhenpeng Qiu
Orlistat (Xenical™), a US Food and Drug Administration (FDA)-approved anti-obesity drug, shows efficacy against multiple tumor types, including hepatocellular carcinoma (HCC), due to its ability to inhibit fatty acid synthase (FASN) activity. However, whether orlistat affects hepatocellular malignant transformation during hepatocarcinogenesis in vivo is unknown. This study assessed the antisteatotic and antitumorigenic efficacy of orlistat in a rapid HCC FVB/N mouse model established via hydrodynamic transfection of activated forms of AKT and c-Met proto-oncogenes. Human hepatoma cell lines were used for mechanical validation in vitro . Hematoxylin and eosin staining, immunohistochemistry, and immunoblotting were applied for the mechanistic investigation. The results revealed that when orlistat was administered in the early stage of AKT/c-Met-triggered hepatocarcinogenesis, it resulted in the elimination of hepatic tumor burden. Mechanistically, orlistat efficiently elevated PTEN expression and suppressed AKT/SREBP1/FASN signaling both in vivo and in vitro , impairing AKT/c-Met-driven de novo lipogenesis and aberrant proliferation. Altogether, this study demonstrates the antilipogenic and antiproliferative efficacy of orlistat in hepatocarcinogenesis, suggesting that orlistat may be beneficial for the treatment of HCC, especially in NAFLD-related HCCs featuring activated AKT/mTOR cascade and increased lipogenesis in livers.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Hao Zhao,Yuebin Zhao,Jiabao Xu,Xin Feng,Guanyu Liu,Yanbing Zhao,Xiangliang Yang
Combination chemotherapy, such as doxorubicin (Dox) plus cisplatin, based on co-assembling nanoparticles plays increasingly important role in the clinical treatment of cancer. But their synergistic antitumor effect is highly limited by unmatched release behavior of Dox and cisplatin. To enhance the synergistic antitumor effect of Dox and cisplatin, herein, an acidic triblock polymer ( p AA 100 - b - p NIPAM 200 - b - p AA 100 , PNA) was developed as a temperature sensitive template for programmable fabrication of two antitumor drugs (Dox and cisplatin). In these co-assembly nanogels, [email protected] nanogels show compact 3D network cisplatin-shell surrounding Dox-loading core, enabling parallel release of Dox and cisplatin, which is beneficial to maximizing the synergistic effect of Dox and cisplatin. Moreover, [email protected] nanogels could be efficiently internalized into tumor cells mainly by caveolin-mediated pathway. In in vivo evaluation on 4T1-bearing BALB/c mice, after single injection, [email protected] nanogels exhibited much stronger suppression of tumor growth, proliferation and metastasis, and induction of apoptosis and necrosis of tumor tissue/cells than [email protected] + [email protected] and [email protected] groups thanks to the parallel release of Dox and cisplatin. In addition, [email protected] nanogels showed a distinct transition from free-flowing sol to free-standing gel at critical gellating temperature (CGT), facilitating the long-term tumor retention and the optimally synergistic antitumor effect of Dox and cisplatin. The programmable fabrication with PNA was promising to be developed as an efficient approach for improving the antitumor efficacy of combination chemotherapy.
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