MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 11
·1-11
·
IF 5.3
Jin Yao,Ai Wenhui,Chen Ge,Zhang Guodong,Wang Fang,Zhou Ting,Zhang Zhiqing,Wang Xiufeng
CuO nanoparticles with good water solubility and uniform particle size were successfully prepared. Interestingly, the oxidase-like activity of CuO NPs was continuously enhanced by the addition of thiourea (TU), and the enzyme activity was further enhanced by the addition of aluminum ion (Al 3+ ). By systematically exploring and optimizing the experimental conditions, including the key parameters such as temperature, reaction time, and pH, a fluorescence-colorimetric dual-mode sensing system based on CuO nanoparticles was constructed. The detection range of TU and Al 3+ were 1-100 µM and 1-100 µM, respectively, and the selectivity and precision of detection were further improved. In addition, the catalytic mechanism of CuO NPs as oxidase-like catalysts and the specific process in the reaction were investigated. Finally, the nano-sensing system was successfully applied to the analysis of three real environmental samples, namely, tap water, lake water and river water, which provided an effective new strategy for the future development of nano-sensing technology for TU and Al 3+ . Graphical
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Science China-Chemistry
·
2025
·
IF 9.7
Xu Xihan,Li Juan-Juan,Li Jiamin,Zhang Hui-Yan,Qi Yilin,Shi Bing-Sen,Li Tianqi,Su Shan-Shan,Zhao Weitao,Chen Chang,Gong Zhongying,Liu Huiyu,Wang Ke-Rang,Guo Dong-Sheng,Xue Xue
The management of acute ischemic stroke remains challenging due to its abrupt onset and the narrow treatment window, resulting in high rates of disability and mortality. Combination therapy for neuroprotection and neurorepair strategies provided new hopes for subacute stroke treatment. Here we designed a multistage nanodelivery system that matches the unique microenvironment of the subacute phase of stroke, which utilizes calixarene as a building block to effectively load the neuroprotective drug simvastatin. The calixarene is designed with glycosidic linkages targeting the glucose transporter 1 (GLUT1) on the blood-brain barrier (BBB) and azo bonds that are responsive to hypoxic conditions. Additionally, the decomposed calixarene molecules themselves possess intrinsic bio-activation to modulate inflammatory responses, achieving a multistage therapeutic approach that transitions from targeting to release and finally to treatment. This approach combines anti-inflammation and neuroprotection, providing a multi-level treatment strategy. This system was validated in a rat model of permanent middle cerebral artery occlusion (pMCAO), demonstrating that intravenous administration of the nanodelivery system repairs brain damage and improves motor function 24 h post-pMCAO induction. This work offers a precise and integrative strategy for stroke patients missing the acute therapy window to improve functional recovery and enhance the effect of comprehensive treatment.
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JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Liu Tingrui,Zhang Jiahui,Zhong Zixi,Huang Xiaofeng,Yu Jian,Wang Yuan,Yuan Shaojun
Nanocomposites consisting of conducting polymers and metal oxide are promising material in electrochemical energy storage. The design of nanostructure is regarded as an efficient strategy to improve electron and ion transfer. However, the construction of nanocomposites usually needs multistep reaction. Herein, a poly(3,4-ethylenedioxythiophene)-encapsulated iron oxide/carbon nanotube nanocomposite (Fe 2 O 3 /CNTs@PEDOT) is demonstrated as an efficient anode for aqueous supercapacitors. The Fe 2 O 3 /CNTs nanocomposite is firstly constructed by a rapid combustion strategy, which provided electrode a good hydrophilic ability. The PEDOT is further in situ constructed on the surface of Fe 2 O 3 /CNTs by an electrochemical polymerization process for enhancing the cycling stability. The Fe 2 O 3 /CNTs@PEDOT electrode delivers an enhanced ions transfer and stability during the charge/discharge process. In 1 M Na 2 SO 4 , such Fe 2 O 3 /CNTs@PEDOT-180 s electrode delivers a specific capacitance of 1014 mF cm −2 at 2 mA cm −2 and retains 89.7% of initial capacitance at 20 mA cm −2 after 3000 cycles, which is superior than that of the Fe 2 O 3 /CNTs electrode (79.2%). The asymmetric aqueous supercapacitor consisted of Fe 2 O 3 /CNTs@PEDOT and MnO 2 /CC electrodes with an operating potential of 2.0 V reaches a high areal energy density of 0.207 mWh cm −2 at a power density of 2.0 mW cm −2 . Graphical abstract
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MICROCHIMICA ACTA
·
2024
·Vol. 192
·期 1
·1-11
·
IF 5.3
Liu Shuang,Yan Peng,Naveed Shahzad,Zhu Yuheng,Fu Tao,Wu Ruijing,Wu Yayan
A colorimetric sensor array is proposed for ultrasensitive detection and identification of bacteria by using Cl − at various concentrations as sensing elements and triangular silver nanoparticles (T-AgNPs) as a single sensing nanoprobe. T-AgNPs are easily etched by Cl − . However, in the presence of bacteria, the etching process will be hindered. Different bacteria have differential protective effects on T-AgNPs due to their interactions, resulting in different etching degrees of T-AgNPs by Cl − , and visual color changes. By adjusting the antagonistic action between bacteria protection on T-AgNPs and the etching by using Cl − at various concentrations, different bacteria had their own color response patterns. Combined with linear discriminant analysis (LDA) and orthogonal partial least squares-discriminant analysis (OPLS-DA), the bacteria could be identified. The method was also used for bacteria mixtures identification and showed high sensitivity (OD 600 = 1.0 × 10 −6 ) for V. parahaemolyticus detection. Finally, the sensor array was successfully utilized in the identification of bacteria in pure and mineral bottled water. The method is low-cost, simple, sensitive, visual, and has potential application in point-of-care testing of bacteria. Graphical
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Science China-Chemistry
·
2024
·
IF 10.4
Qiang Yue,Cao Huaiman,Pan Yuzhen,Chi Yi,Zhao Liangyu,Yang Yingguo,Li Hai-Bei,Gao Yan,Sun Licheng,Yu Ze
Metal phthalocyanines (MPcs) have gained considerable research attention as hole-transport materials (HTMs) in perovskite solar cells (PSCs) because of their superb stability. However, the photovoltaic performance of MPc-based HTMs in PSCs is still lagging behind their small molecule and polymeric counterparts, largely due to their relatively low hole mobility. Here, we report for the first time the application of a copper naphthalocyanine derivative (namely t Bu-CuNc) as a hole-transport material (HTM) in perovskite solar cells (PSCs), and systematically study its optoelectronic and photovoltaic property compared with its CuPc analog (tBu-CuPc). Combined experiments disclose that the extension of π -conjugation from Pc to Nc core leads to not only an enhanced hole-carrier mobility associated with a stronger intermolecular interaction, but also an elevated glass transition temperature ( T g ) of 252 °C. The resultant PSCs employing t Bu-CuNc deliver an excellent power conversion efficiency of 24.03%, which is the record efficiency reported for metal complex-based HTMs in PSCs. More importantly, the encapsulated t Bu-CuNc-based devices also show dramatically improved thermal stability than the devices using the well-known Spiro-OMeTAD, with a T 80 lifetime for more than 1,000 h under damp-heat stress. This study unfolds a new avenue for developing efficient and stable HTMs in PSCs.
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CATALYSIS LETTERS
·
2025
·Vol. 155
·期 3
·1-12
·
IF 2.4
Yu Shuxiu,Yuan Shixiong,Li Liang,Wang Ling,Chen Jianjun
Electro-reduction of CO 2 (CO 2 RR) to formic acid is one of the most efficient and promising technologies for the utilization of CO 2 , however, designing catalysts with high reactivity and selectivity to achieve the conversion of CO 2 to formic acid is still a great challenge. Therefore, in this study, Bi 2 O 3 -ZnO/ZnAl 2 O 4 composite oxide catalysts were constructed using layered double hydroxides as precursors to enhance the interfacial stability and utilize the synergistic effect of zinc-bismuth dual active sites for the efficient electrocatalytic reduction of CO 2 to formate. The product formate bias current density reached up to 25.8 mA·cm − 2 at -1.3 V (vs. RHE) in an H-type electrolytic cell and the Faraday efficiency of formate was maintained at about 93% under stability tests up to 14 h, which was superior to most other reported catalysts. In the formation of the Bi 2 O 3 -ZnO/ZnAl 2 O 4 interface, zinc promotes the electroreduction of CO 2 to produce *CO 2 − intermediates, while bismuth reduces CO production and improves formic acid selectivity by providing more reactive sites. In addition, the interface between zinc and bismuth optimizes electron and proton flow, helping to maintain a lower energy threshold during the reaction and thus improving catalytic efficiency. This interface engineering approach utilizes zinc-bismuth dual active sites to achieve high selectivity and stability of CO 2 electrocatalytic reduction, providing insights for the development of large-scale efficient CO 2 RR catalysts in the future. Graphical
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Nano-Micro Letters
·
2024
·Vol. 17
·期 1
·1-15
·
IF 31.6
An Li,Li Jianyi,Sun Yuanmiao,Zhu Jiamin,Seow Justin Zhu Yeow,Zhang Hong,Zhang Nan,Xi Pinxian,Xu Zhichuan J.,Yan Chun-Hua
Demonstrate that the key factor to determine the activity of reconstructed surfaces is the surface chemistry, instead of reconstruction degree using the popular perovskite LaNi 1-x Fe x O 3 oxides as model materials.
Fe content can influence both the surface reconstruction degree, the activation degree, and the activity of reconstructed surfaces.
The oxygen evolution reaction activity of reconstructed catalysts is primarily governed by the chemistry of the reconstructed surface species.
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CATALYSIS LETTERS
·
2017
·Vol. 147
·期 7
·1802-1810
·
IF 2.799
Hong Runrun,He Yufei,Miao Chenglin,Feng Junting,Li Dianqing
Abstract Pd–Ir mesocrystals with rough surface and highly branched structure were synthesized through a facile co-reduction method. The morphology evolution shows the mesocrystals were formed by oriented attachment of nanoparticles, and abundant defects sites as well as synergetic effect between building units were formed during mesocrystals oriented attachment process. Therefore, the supported Pd–Ir mesocrystals show a significant enhancement in catalytic performance in hydrogenation of 2-ethylanthraquinone compared with conventional Pd–Ir nanoparticles. The high activity can be ascribed to high densities of defect sites in Pd–Ir MCs catalyst, which facilitated H 2 activation. In addition, the geometric effect of Pd–Ir MCs catalyst was responsible for inhibiting further hydrogenation of eAQH 2 to undesired consecutive byproducts. Graphical Abstract
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FIBERS AND POLYMERS
·
2017
·Vol. 18
·期 5
·891-899
·
IF 1.113
Wang Yixi,Zhang Chongyang,Zhao Linyan,Meng Guihua,Wu Jianning,Liu Zhiyong
A novel cellulose-based porous adsorbent with high adsorption capacity for methylene blue (MB) was prepared by free radical polymerization methods. The obtained polymer grafting rate and dye removal efficiency are as high as 338.64 % and 97.74 %, respectively, when the dosage of monomer is 4.5 g, the polymerization condition is 3 h at 70 °C. The cellulose-based adsorbent showed high mechanical properties and good flexibility. The Langmuir isotherm model revealed that the maximum theoretical adsorption capacity of this material for methylene blue was 1734.816 mg g-1 at pH 9.0 at 313 K, which is higher than the values observed for other adsorbents. Scanning electron microscopy (SEM) showed that the cellulose-based adsorbent exhibits a typical well-defined porous and interconnected three-dimensional framework structure, which is benefits to dye adsorption. The adsorption kinetics (pseudo first-order, pseudo-second-order, and intraparticle diffusion models) was also studied, and the pseudo-second-order model fitted MB adsorption better than the pseudo-first-order and intraparticle diffusion models at different initial dye concentrations (500-3000 mg l
-1 ). The novel polyacrylic acid-grafted quaternized cellulose (PAA- g -QC) adsorbent is thus potentially useful for the treatment of dye-contaminated wastewater.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2017
·Vol. 28
·期 16
·12297-12305
·
IF 2.019
Hou Baoting,Wang Xinlu,Yao Jing,Zhang Hongbo,Yu Wensheng,Liu Guixia,Dong Xiangting,Wang Limin,Wang Jinxian
A simple and novel method based on recrystallization-sulfurization method has been developed to fabricate Ce 2 S 3 /MoS 2 composite and their structure, morphology and electrochemical performance is researched systematically. The Ce 2 S 3 /MoS 2 composite exhibit enhanced electrochemical performance compared with Ce 2 S 3 and MoS 2 . Among them, Ce 2 S 3 /MoS 2 composite has an initial reversible discharge capacity of 187.5 mAh g −1 , coulombic efficiency of 78.6% and a reversible capacity as high as 636.5 mAh g −1 , coulombic efficiency of 99.7% after 500 cycles at a current density of 100 mA g −1 and the highest discharge capacity of 97.3 mAh g −1 at a high current density of 1000 mA g −1 , showing the best reversible capacity and cycling performance. The results show that the compositing between MoS 2 and Ce 2 S 3 can maintain the stability of the structure during the charge/discharge process and existence of Ce 2 S 3 can enhance the electrical conductivity of Ce 2 S 3 /MoS 2 composite and further improves the reversible capacities, cycling performance and rate performance of Ce 2 S 3 /MoS 2 composite.
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Nanoscale Research Letters
·
2017
·Vol. 12
·期 1
·1-8
·
IF 2.833
Wang Haiyan,Sheng Weizhong
Herein, folic acid (FA) conjugated Poly(d,l-lactide-co-glycolide) (PLGA)-lipid composites (FA-PL) were developed as nanocarriers for the targeted delivery of insoluble anti-cancer drug paclitaxel (PTX), resulting FA-PLP nanoparticles. Furthermore, 131 I, as a radioactive tracer, was used to label FA-PLP nanoparticles (FA-PLP- 131 I) to evaluate their cell uptake activity, in vivo blood circulation, and biodistribution. The FA-PLP- 131 I nanoparticles had a spherical morphology with great stability, a narrow size distribution (165.6 and 181.2 nm), and −22.1 mV in average zeta potential. Confocal laser scanning microscopy indicated that the targeting molecule FA promotes PLP- 131 I uptake by melanoma B16F10 cells, which was further confirmed by the cell incorporation rate via 131 I activity detection as measured by a gamma counter. FA-PLP- 131 I without PTX (FA-PL- 131 I) shows minor cytotoxicity, good biocompatibility, while FA-PLP- 131 I was demonstrated to have efficient cell viability suppression compared to free PTX and PLP- 131 I. Following intravenous injection, the blood circulation half-life of free PTX ( t
1/2 = 5.4 ± 0.23 h) was prolonged to 18.5 ± 0.5 h by FA-PLP- 131 I. Through FA targeting, the tumor uptake of FA-PLP- 131 I was approximately 4.41- and 12.8-fold higher compared to that of PLP- 131 I and free PTX- 131 I, respectively. Moreover, following 40 days of treatment, FA-PLP- 131 I showed an improved tumor inhibition effect compared to free PTX and PLP- 131 I, with no relapse and no remarkable systemic in vivo toxicity. The results demonstrate that the 131 I-labeled PLGA-lipid nanoparticle can be simultaneously applied for targeted drug delivery and reliable tracking of drugs in vivo.
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Discover Oncology
·
2024
·Vol. 15
·期 1
·1-13
·
IF 2.8
Deng Chunmin,Zhang Hao,Song Li
Nanoparticle-based photothermal therapy (PTT) has emerged as a promising approach in tumor treatment due to its high selectivity and low invasiveness. However, the penetration of near-infrared light (NIR) is limited, leading it fails to induce damage to the deep-seated tumor cells within the tumor tissue. Additionally, inefficient uptake of photothermal nanoparticles by tumor cells results in suboptimal outcomes for PTT. In this study, we utilized the adhesive properties of photothermal material, polydopamine (PDA), which can successfully load the photosensitizer indocyanine green (ICG) and chemotherapeutic drug doxorubicin (DOX) to achieve photothermal and chemotherapy synergy treatment (PDA/DOX&ICG), aiming to compensate the defects of single tumor treatment. To extending the blood circulation time of PDA/DOX&ICG nanoparticles, evading clearance by the body immune system and achieving targeted delivery to tumor tissues, a protective envelopment was created using erythrocyte membranes modified with folate acid (FA-EM). After reaching the tumor tissue, the obtained FA-EM@PDA/DOX&ICG nanoparticles can specific bind with folate acid receptors on the surface of tumor cells, which can improve the uptake behavior of FA-EM@PDA/DOX&ICG nanoparticles by tumor cells, and leading to the release of loaded DOX and ICG in response to the unique tumor microenvironment. ICG, as a typical photosensitizer, significantly enhances the photothermal conversion performance of FA-EM@PDA/DOX&ICG nanoparticles, thus inducing tumor cells damage. In vitro and in vivo experimental results demonstrated that the coordinated NIR treatment with FA-EM@PDA/DOX&ICG not only effectively inhibits tumor growth, but also exhibits superior biocompatibility, effectively mitigating DOX-induced tissue damage.
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