FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Chenzhi Wang,Yan Li,Wei Xiong,Qiang Liang,Xin Hua,Pu Xuan,Wei Lin,Yingzheng Yao
The correlation between the structural parameters of droplets and rheological properties of O/W high internal phase Pickering emulsions (HIPPEs) stabilized by soy protein isolate (SPI) nanoparticles was elucidated, with a volume fraction of dispersed phase ( ϕ ) above the closest packing density (74%). The structural basis of SPI nanoparticles was confirmed to be spherical heat-induced protein aggregates, which had moderate wettability and excellent interfacial activity. The structural parameters of emulsion droplets (contact length L , diameter D , length d 1 , width d 2 , the number of adjacent contact droplets Z ), and the stability and rheological properties of HIPPEs were characterized by the confocal laser scanning microscopy (CLSM), diffusing wave spectroscopy (DWS), and mechanical rheometer respectively. The results of CLSM indicated the transition of droplets from spherical to polyhedral shapes as increased ϕ , accompanied by an increased L and Z . The rheological and stability analysis confirmed the widened linear viscoelastic range, elevated gel point ( ε c ), and the extended half−life of the intensity autocorrelation function of HIPPEs as ϕ increased. Moreover, the loss factor (tan δ ) remained constant at 0.1 within the ϕ of 74%–86%, revealing the solid−like nature of HIPPEs. The correlation between ϕ , structural parameters of droplets, and rheological properties of HIPPEs was further analyzed. The nonlinear regression fitting between the L / D and G ' (elastic modulus) yielded a better fitting effect than d 1 / d 2 and Z , suggesting an intrinsic correlation between emulsion structure and rheology. In summary, this study elucidated the intricate relationship between ϕ , droplet structure, and rheological properties of HIPPEs, offering a research foundation and theoretical basis for the development and application of protein particle−stabilized HIPPEs.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Shixian Chen,Gaohui Du,Yan Cheng,Di Han,Jiahao Deng,Yunting Wang,Huayu Li,Libing Yao,Dong Wang,Qingmei Su,Bingshe Xu
Lithium-sulfur (Li-S) batteries are poised to become the next-generation energy storage technology due to their ultra-high energy density of 2600 Wh kg −1 and the abundant reserves of sulfur on Earth. However, the practical use of Li-S batteries faces several challenges related to sulfur cathodes, including low sulfur loading, significant volumetric expansion, slow conversion kinetics, and the shuttle effect caused by polysulfides. To tackle these challenges, we have developed a hierarchical porous carbon co-doped with nitrogen, oxygen, and sulfur heteroatoms (NOSHPC) that is further loaded with monodispersed vanadium nitride quantum dots (VNQDs). This innovative combination serves as an efficient catalytic matrix to enhance charge transfer processes and facilitate the anchoring and conversion of lithium polysulfides. Moreover, we have fabricated dry-processed cathodes with ultrahigh sulfur loading by using fibrotic polytetrafluoroethylene (PTFE) as a binder, replacing the toxic solvent N-methyl-2-pyrrolidone and polyvinylidene fluoride. The dry-processed VNQDs/NOSHPC/S cathodes demonstrate a remarkable specific capacity of 1655mAh g −1 at 0.1C and achieve exceptional cycling stability, with a decay rate of only 0.0107 % per cycle over 1000 cycles at 1C with a sulfur loading of 5.2 mg cm −2 . Additionally, the pouch cells containing these dry-processed electrodes exhibit a practical areal capacity of 14.2mAh cm −2 (462 Wh kg −1 ) with a sulfur loading of up to 18.6 mg cm −2 and a low electrolyte-to-sulfur ratio of 5.3μL mg −1 . This work presents an innovative strategy for creating sulfur hosts and practical dry-processed Li-S electrodes, highlighting promising prospects for industrial application.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
·
2024
·
IF 4.8
Yun-Lu Xu,Xue-Jian Li,Wei Cai,Wen-Ying Yu,Jing Chen,Qin Lee,Yong-Jun Choi,Fang Wu,Ying-Jun Lou,Hua-Zhong Ying,Chen-Huan Yu,Qiao-Feng Wu
Ethnopharmacological relevance Viral pneumonia is the leading cause of death after SARS-CoV-2 infection. Despite effective at early stage, long-term treatment with glucocorticoids can lead to a variety of adverse effects and limited benefits. The Chinese traditional herb Pogostemonis Herba is the aerial part of Pogostemon Cablin (Blanco) Benth., which has potent antiviral, antibacterial, anti-inflammatory, and anticancer effects. It was used widely for treating various throat and respiratory diseases, including COVID-19, viral infection, cough, allergic asthma, acute lung injury and lung cancer. Aim of the study To investigate the antiviral and anti-inflammatory effects of chemical compounds from Pogostemonis Herba in SARS-CoV-2-infected hACE2-overexpressing mouse macrophage RAW264.7 cells and hACE2 transgenic mice. Materials and methods The hACE2-overexpressing RAW264.7 cells were exposed with SARS-CoV-2. The cell viability was detected by CCK8 assay and cell apoptotic rate was by flow cytometric assay. The expressions of macrophage M1 phenotype markers (TNF-α and IL-6) and M2 markers (IL-10 and Arg-1) as well as the viral loads were detected by qPCR. The mice were inoculated intranasally with SARS-CoV-2 omicron variant to induce viral pneumonia. The levels of macrophages, neutrophils, and T cells in the lung tissues of infected mice were analyzed by full spectrum flow cytometry. The expressions of key proteins were detected by western blot assay. Results Diosmetin-7-O-β-D-glucopyranoside (DG) presented the strongest anti-SARS-CoV-2 activity. Intervention with DG at the concentrations of 1.25-50 μM not only reduced the viral replication, cell apoptosis, and the productions of inflammatory cytokines (IL-6 and TNF-α) in SARS-CoV-2-infected RAW264.7 cells, but also reversed macrophage polarity from M1 to M2 phenotype. Furthermore, treatment with DG (25-100 mg/kg) alleviated acute lung injury, and reduced macrophage infiltration in SARS-COV-2-infected mice. Mechanistically, DG inhibited SARS-COV-2 gene expression and HK3 translation via targeting YTHDF1, resulting in the inactivation of glycolysis-mediated NF-κB pathway. Conclusions DG exerted the potent antiviral and anti-inflammatory activities. It reduced pneumonia in SARS-COV-2-infected mice via inhibiting the viral replication and accelerating M2 macrophage polarization via targeting YTHDF1, indicating its potential for COVID-19 treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2012
·
IF 1.693
Baimei Yang,Hui Wan,Guofeng Guan
Isobaric vapor–liquid equilibrium (VLE) data are reported for binary mixtures of methyl formate + o-xylene, methyl formate + m-xylene, methyl formate + p-xylene, and methyl formate + ethylbenzene at 101.33 kPa. The data are obtained using a vapor recirculating type (modified Othmer's) equilibrium still. All of the binary systems show positive deviation from ideality. None of the systems form an azeotrope. The VLE data for these binary systems are checked to meet rigorous thermodynamic consistency by the Herington method and the point-to-point test of the Fredenslund method. The experimental VLE data are well-correlated by the nonrandom two-liquid (NRTL), universal quasichemical activity coefficient (UNIQUAC), and Wilson equations.
✓ 已验证
产品关联
DOI
高影响因子
ENERGY & FUELS
·
2024
·
IF 5.2
Lan Li,Tingxue Fang,Fuming Lai,Xinyue Li,Tingting Qu,Lin Wang,Xiaoshi Lang,Kedi Cai
Vanadium pentoxide (V2O5) is regarded as a promising sulfur-wrapped matrix for high-performance lithium–sulfur batteries, owing to its desirable structural and functional characteristics. In this paper, a large number of defective sites arise in the vanadium pentoxide structure via a codecoration strategy of the V, O sites, which is more beneficial to improving the electroconductivity and allows for the uniform loading of sulfur on the surface, thereby reducing the polarization resistance and elevating the kinetic rates during the electrochemical reaction. Electrochemical test results indicate that Mg2+/S-codecorated V2O5/S composite cathodes have 1131.15, 942.39, and 804.71 mAh·g–1 of discharge-specific capacities at 0.1, 0.2, and 0.5 C rates, respectively, with the lowest charge/discharge plateau voltage difference, and the capacity retention rate after 140 cycles can be 57.95%. Besides that, the multidefect V2O5 can effectively promote the adsorption strength of lithium polysulfide and catalytically accelerate the rate of liquid-phase conversion between lithium polysulfide so as to achieve the stable electrochemical properties for sulfur composite cathodes.
✓ 已验证
产品关联
DOI
高影响因子
PHYTOMEDICINE
·
2024
·
IF 6.7
Tingwen Zhang,Yue Zhong,Yan Shi,Chengcheng Feng,Lu Xu,Zheng Chen,Xin Sun,Yan Zhao,Xialin Sun
Background The pathogenesis of acute liver injury (ALI) has been a pressing issue in the medical scientific community. We previously found that 5-O-methylvisammioside (MeV) from Saposhnikovia divaricata (Turcz.) Schischk has excellent anti-inflammatory properties. However, the mechanism by which MeV protects against ALI still needs to be deeply investigated. Purpose In the present study, we established an acetaminophen (APAP) -induced ALI mouse model and pre-protected the mice with MeV. Methods & Results Our findings indicate that MeV (5 and 10 mg/kg) lowered the blood levels of alanine aminotransferase and aspartate aminotransferase and reduced the infiltration of inflammatory cells in the liver. MeV initially showed an inhibitory effect on ALI. We then analyzed the molecular mechanisms underlying the effects of MeV by transcriptomic and metabolomic analyzes. Through transcriptomic analysis, we identified 4675 differentially expressed genes between the APAP+MeV group and the APAP-induced ALI group, which were mainly enriched in the MAPK pathway, the TNF pathway, and the NF-κB pathway. Through metabolomic analysis, we found that 249 metabolites in the liver were differentially regulated between the APAP+MeV group and the APAP- induced ALI group, which were mainly enriched in the arachidonic acid pathway. The mRNA expression levels of key genes (encoding TNF-α, p38, AP-1, RelB, IL-1β, and Ptges), as determined by RT-PCR analysis, were consistent with the RNA-seq data. The ELISA results indicate that MeV markedly decreased the serum levels of TNF-α and IL-1β in mice. Finally, the key proteins in the NF-κB and MAPK pathways were examined using immunoblotting. The results showed that MeV decreased IκB-α phosphorylation and inhibited the nuclear translocation of NF-κB. In addition, MeV reduced the hepatic inflammatory burst mainly by inhibiting the phosphorylation of p38 and JNK in the MAPK pathway. Conclusion The present study demonstrated (i) that MeV could ameliorate APAP-induced ALI by inhibiting arachidonic acid metabolism and the TNF, MAPK, and NF-κB pathways, and (ii) that MeV is a promising drug candidate for the prevention of ALI.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yun Hu,Jingru Sun,Cuige Zhang,Chunmiao Xia,Liuyan Zhu,Maodong Xu,Rongli Zhang,Yinsheng Fang
Hollow carbon spheres (HCSs) have attracted broad attention in aqueous zinc-ion hybrid supercapacitors (ZIHSCs) owing to their distinctive properties. However, traditional methods for fabricating HCSs face limitations, including complex multistep procedures, the use of corrosive chemicals, and stringent reaction conditions. In this work, biomass-based poly(γ-glutamic acid)/Ni 2+ /melamine/chitosan nanoparticles were used as the precursors to fabricate N/O co-doped hollow graphite carbon spheres (HGCSs). Thanks to the appropriate hydrophilic characteristic, specific surface area, pore size distribution, and electrical conductivity, the fabricated HGCSs cathode exhibited superior electrochemical properties. The assembled HGCSs-based ZIHSCs device showed a satisfactory specific capacitance of 133.2 mAh·g −1 at a current density of 1.0 A·g −1 , high energy densities of 75.2 Wh·kg −1 at 10,000 W·kg −1 and 107.9 Wh·kg −1 at 1000 W·kg −1 , respectively. Additionally, the assembled HGCSs-based ZIHSCs device displayed an exceptional cycling stability, enduring up to 10,000 cycles at 0.5 A·g −1 with a capacity retention rate of 98.1 %. This work provides a facile and novel strategy to prepare superior electrochemical performance biomass-based HGCSs cathode for ZIHSCs.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2025
·
IF 4.9
Rui Li,Wenhui Ruan,Rui Hao,Jue Chen,Chu Xu,Liyan Lu,Yingli Wang
Cannabidiol (CBD) is a natural cannabinoid with anti-epileptic, anti-inflammatory, and other biological activities. However, CBD is highly lipophilic, and its oral bioavailability is only 6%, which greatly limits its efficacy. Here, we aimed to overcome the poor solubility and low oral bioavailability of CBD by formulating O-carboxymethyl chitosan-grafted cholesterol succinate monoester-loaded cannabidiol nanomicelles (CBD/CCMC NMs). The particle size, polydispersity index, and zeta potential of the optimised CBD/CCMC NMs were 230.61 ± 1.82 nm, 0.17 ± 0.05, and -13.52 ± 1.24 mV, respectively. And it showed a spherical structure under scanning electron microscopy, exhibited stability at 25 °C and 37 °C, with pH-dependent release in vitro . There was improved the solubility of CBD in water by 568.67-fold and exhibited excellent biocompatibility. There was also improved bioavailability of CBD. Therefore, CBD/CCMC NMs can be used as delivery systems for improving the solubility and intestinal absorption of hydrophobic drugs.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yachao Xu,Zhong Zhou,Peng Yu,Huiquan Gu,Zixu Zhang,Ying Wang
Efficient reduction of U(VI) to U(IV) during seawater uranium extraction remains a challenge. Here, cerium dioxide quantum dots were bonded to the surface of indium zinc sulfide (ZIS) to form ZIS composite cerium dioxide quantum dots (ZIS/QDs-Ce). The oxygen vacancies are able to activate the Zn-O bonds at the ZIS and QDs-Ce interfaces, thus enabling the constructed S-scheme heterojunction to show great potential in facilitating the separation and transfer of photogenerated carriers. ZIS/QDs-Ce exhibited high anti-bio-pollution activity by generating biotoxic free radical reactive oxygen species (ROS). The photo-induced reduction of uranium by ZIS/QDs-Ce in 10 ppm uranium spiked simulated seawater reached 99.6 %. Oxygen vacancies cause distortions in the crystal field, and the Zn-O bond activation process triggers the movement of ZIS/QDs-Ce from the singlet low-spin state to the stable triplet state, resulting in free-carrier trapping centers and optimized electronic energy band structures. ZIS/QD-Ce has superior uranium extraction capabilities and is highly recommended for uranium extraction from seawater.
✓ 已验证
产品关联
DOI
高影响因子
Metals
·
2025
·Vol. 15
·期 3
·307
·
IF 2.5
Ziyang Ruan,Zifan Zhao,Jing Feng
Rare-earth tantalates (RETaO4) are considered as a type of emerging thermal barrier coating materials applied to the hot components of gas turbines and aerospace engines due to their excellent thermal stability, high-temperature fracture toughness, corrosion resistance and extremely low thermal conductivity. However, the relatively low hardness and thermal expansion coefficients may limit their service lifetime in a harsh engine environment. To address the current limitation of rare-earth tantalates and further optimize the mechanical and thermal properties, the defective fluorite-structured Y₂Zr₂O₇ (YZ) was introduced as a second phase into the YTaO4(YT) matrix to form YT1−x–YZx(x = 0, 0.25, 0.5, 0.75, 1) composite ceramics in this work. The mechanical and thermal properties of YT1−x–YZxcomposite ceramics are significantly improved compared to pure-phase YTaO4ceramics. The Vickers hardness of YT1−x–YZx(x = 0.25, 0.5, 0.75) composite ceramics is 9.1~11.3 GPa, which are 2~2.5 times higher than that of YTaO4(4.5 GPa). Among them, YT0.75–YZ0.25exhibits a maximum fracture toughness (3.7 ± 0.5 MPa·m1/2), achieving a 23% improvement compared to YTaO4(3.0 ± 0.23 MPa·m1/2) and a 118% improvement compared to Y2Zr2O7(1.73 ± 0.28 MPa·m1/2). The enhancement is attributed to the combined effect of the intrinsic strengthening of the second phase, as well as the residual stress and grain refinement caused by the introduction of a second phase. Additionally, the thermal expansion coefficients of YT1−x–YZxcomposite ceramics at 1673 K range from 10.3 × 10⁻⁶ K⁻1to 11.0 × 10⁻⁶ K⁻1, which is also higher than that of YTaO4(10.0 × 10−6K−1). Consequently, the superior mechanical and thermal properties indicate that YT–YZ composite ceramics possess promising application prospects for thermal barrier coatings.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Qingcai Yu,Ying Chang,Shaohong Guo,Yaqiong Su,Jingchun Jia,Meilin Jia
In direct formic acid fuel cells, the formic acid oxidation reaction (FAOR) takes place at the anode, and the oxygen reduction reaction (ORR) occurs at the cathode. Whereas the cathode of zinc-air batteries (ZABs) also involves the ORR, these three electrochemical reactions collectively constitute the core processes of related energy devices. The study of the catalytic performance of palladium (Pd)-based catalysts has become a research focus. This study explores the utilization of rare earth metal-organic frameworks to enhance the interface interactions between Pd and CeO 2 . These frameworks facilitate the modulation of the electronic state of Pd, ensure site stability, and promote the generation of additional oxygen vacancies through bridge bonding between Pd–O–Ce. The Pd-CeO 2 /C(1:2) catalyst in 0.5 M H 2 SO 4 exhibited high initial potential (0.86 V vs. reversible hydrogen electrodes (RHE)), half-wave potential (0.76 V vs. RHE), excellent ORR stability, and exceptional performance in ZAB cathodes with a power density reaching 195.4 mW·cm −2 . Furthermore, in FAOR (0.5 M H 2 SO 4 + 0.5 M HCOOH) applications, this catalyst displays significantly higher activity (991.4 mA·mg −1 ) and stability than commercial Pd/C and platinum/C catalysts while maintaining excellent selectivity for formic acid decomposition. Theoretical calculations further prove that the formation of the Pd–O–Ce bridge bond is conducive to FAOR's direct reaction pathway and avoids CO toxicity. The Pd-CeO 2 /C(1:2) catalyst is utilized in positive and negative electrodes within self-assembled H-type electrolytic cells, achieving open-circuit voltages superior to those offered by commercial catalysts, thus confirming its practical applicability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Enjing Huang,Ziling Li,Fangyuan Zhou,Qinyu Chen,Jiayong He,Xiangyuan Xiong,Youfa Xie,Hongxia Gao,Liqiang Zou
Probiotics offer health benefits but often lose viability during processing and digestion, hindering their use. Therefore, we developed oil-phase gel O/W high internal phase emulsions (HIPEs) by incorporating beeswax to encapsulate Lactiplantibacillus plantarum subsp. Plantarum ( L. plantarum ). The incorporation of 1% and 2% beeswax reduced droplet size while improving the physical stability and strengthening the gel structure of the HIPEs. Crucially, incorporating beeswax markedly improved the retention of L. plantarum within the HIPEs oil phase. In addition, the oil-phase gelled HIPEs enhanced the thermal resistance of L. plantarum at 72 °C and 65 °C. It also imparted storage stability, which was 7.42 log 10 CFU/g with 1% beeswax for 30 days storage at 4 °C. The addition of beeswax to the oil phase of HIPEs minimized L. plantarum 's viability loss in the gastrointestinal tract. This study contributes to the development of a probiotic emulsion encapsulation system that reaches the colon with high viability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）