ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Xinyuan Lyu,Luchao Ren,Le Xin,Zhengxin Li,Xianxin Zhang,Zheng Luo,Pengchao Shao,Yuxiao Zhang,Panpan Lyu,Mingwei Zhang
Fabrication of low-temperature co-fired ceramic (LTCC) densified at a low sintering temperature (<900 °C) is energy saving and environmentally friendly. Here, an interesting attempt has been made to lower the sintering temperature of MgGa2O4 by adding CuMoO4 for LTCC application. The sintering temperature of MgGa2O4 was remarkably reduced from 1410 to 900 °C, which contributed to energy saving. Furthermore, a series of studies on microstructure, sintering behavior, lattice parameters, and microwave dielectric characteristic of the samples were carried out. The occurrence of ion substitution between MgGa2O4 and CuMoO4, which affected the sintering densification, ionic polarizability, and Mg–O bond length, made the composites present various sintering and dielectric properties. Moreover, the full width half maximum (FWHM) value of the T2g peak in Raman spectra and lattice distortion were also analyzed to reveal the intrinsic interaction between structure and dielectric properties. Finally, the 0.5MgGa2O4–0.5CuMoO4 ceramics sintered at 900 °C showed the best comprehensive performance, εr = 6.8, Q × f = 15,800 GHz, τf = −54.2 ppm/°C. These promising properties make the composite more suitable for practical application.
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JOURNAL OF BIOMATERIALS APPLICATIONS
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2023
·
IF 2.9
Mengyu Zhu,Yang Zhang,Chi Zhang,Lei Chen,Ying Kuang
Oxidative damage of neurons is one of the key pathological markers of Alzheimer’s disease (AD), which eventually leads to neuronal apoptosis and loss. Nuclear factor E2-related factor 2 (Nrf2) is a key regulator of antioxidant response and is considered to be an important therapeutic target for neurodegenerative diseases. In this study, the selenated derivative of antioxidant rutin (Se-Rutin) was synthesized with sodium selenate (Na2SeO3) as raw material by a simple electrostatic-compound in situ selenium reduction method. The effects of Se-Rutin on H2O2 induced oxidative damage in Pheochromocytoma PC12 cells were evaluated by cell viability, apoptosis, reactive oxygen species level and the expression of antioxidant response element (Nrf2). The results showed that H2O2 treatment significantly increased the level of apoptosis and reactive oxygen species, while the level of Nrf2 and HO-1 decreased. However, Se-Rutin significantly reduced H2O2 induced apoptosis and cytotoxicity, and increased the expression of Nrf2 and HO-1, both of which were better than that of pure rutin. Therefore, the activation of Nrf2/HO-1 signaling pathway may be the basis of Se-Rutin’s anti-oxidative damage to AD.
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PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 47
·期 3
·1094-1104
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IF 3.925
Hui Luo,Yang Han,Kaiyuan Hu,Jia Li,Dickon H. L. Ng,Xiaodi Ma,Kairui Luan,Mingkang Yang
Herein, we demonstrate a novel Fe3O4@MnO2@HKUST-1 magnetic micromotor with excellent peroxidase-like activity for highly efficient colorimetric detection and degradation of hydroquinone. Such micromotors had unique flower-like morphology with highly exposed active sites. The resulting MnO2-based micromotor was propelled by O2 bubbles generated from hydrogen peroxide fuel catalyzed by MnO2, and the velocity could be adjusted by the H2O2 fuel concentration. The self-propelled motion of the Fe3O4@MnO2@HKUST-1 could effectively increase the collision probability between active sites and pollutant molecules, and thus, enhanced the sensitivity of the colorimetric detection as well as the degradation efficiency. These excellent results confirm that this Fe3O4@MnO2@HKUST-1 micromotor has good prospects for future use in water treatment applications.
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FOOD AND AGRICULTURAL IMMUNOLOGY
·
2022
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IF 3.268
Peizhen Li,Xiuhua Xia,Jiannan Chen,Hang Yu,Yunfei Xie,Yahui Guo,Weirong Yao,He Qian,Yuliang Cheng
Gold-coated silver core–shell nanoparticles (Ag@Au NPs) have been widely used for SERS analysis due to plasmon resonance performances. However, it is a great challenge to fabricate Ag@Au core–shell structures with specified morphology. In this paper, the size and shape of Ag NPs (core) were precisely controlled by a seed-mediated approach, and then the gold shell was completely coated on under the strong reduction of ascorbic acid, resulting in Ag@Au NPs with highly regulated morphology. The obtained Ag@Au NPs achieved a similar or even better SERS enhancement factor (EF) (up to 5.7 × 107) compared to Ag NPs, but significantly higher stability. For the rapid SERS detection of nitrofurantoin metabolite AHD, a limit of detection (LOD) as low as 1 × 10−10 M and a wide linear range from 1 × 10−4 to 1 × 10−8 M were obtained. Furthermore, recoveries for crayfish samples were from 90.5% to 108%, indicating a good performance of the presented method in real sample detection.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 24
·期 1
·320
·
IF 6.208
Xiaoyu Zhang,Yuan Gao,Zhuangzhuang Liu,Wenjing Li,Yuan Kang,Ximeng Li,Zhenlu Xu,Cheng Peng,Yun Qi
As a worldwide health issue, obesity is associated with the infiltration of monocytes/macrophages into the adipose tissue causing unresolved inflammation. Monocyte chemoattractant protein-1 (MCP-1) exerts a crucial effect on obesity-related monocytes/macrophages infiltration. Clinically, aspirin and salsalate are beneficial for the treatment of metabolic diseases in which adipose tissue inflammation plays an essential role. Herein, we investigated the effect and precise mechanism of their active metabolite salicylate on TNF-α-elevated MCP-1 in adipocytes. The results indicated that salicylate sodium (SAS) could lower the level of MCP-1 in TNF-α-stimulated adipocytes, which resulted from a previously unrecognized target phosphodiesterase (PDE), 3B (PDE3B), rather than its known targets IKKβ and AMPK. The SAS directly bound to the PDE3B to inactivate it, thus elevating the intracellular cAMP level and activating PKA. Subsequently, the expression of MKP-1 was increased, which led to the decrease in p-EKR and p-p38. Both PDE3B silencing and the pharmacological inhibition of cAMP/PKA compromised the suppressive effect of SAS on MCP-1. In addition to PDE3B, the PDE3A and PDE4B activity was also inhibited by SAS. Our findings identify a previously unrecognized pathway through which SAS is capable of attenuating the inflammation of adipocytes.Keywords:cAMP;MKP-1;p-ERK;p-p38;metaflammation
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高影响因子
Fermentation-Basel
·
2023
·Vol. 9
·期 2
·133
·
IF 3.7
Peng Cheng,Muhammad Usman,Muhammad Arslan,Huanqing Sun,Li Zhou,Mohamed Gamal El-Din
A Gram-positive exoelectrogenRhodococcus pyridinivoranssp. strain HR-1 was cultivated from leachate-fed microbial fuel cell (MFC) to study the biodegradation effect of pyridine. In the comparison with mixed cultured MFC, HR-1 presented a remarkable electrical capacity with a maximum output of 4.33 W/m3under 30 °C in neutral anolyte with 1 g/L acetate as a substrate. Further, HR-1 demonstrated the environmental resistance as a Gram-positive strain. Microbial metabolism was evident at pH between 5–9 and temperature in the range of 20–40 °C, whereas optimal condition for pyridine degradation was observed at 30 °C. This is the first study reporting the degradation of pyridine in the bio-electrochemical system that achieved a 42% ± 5% degradation rate in a full operation cycle at 2 g/L of the concentration. Considering the nonnegligible internal resistance of HR-1-inoculated MFC, trehalose lipid was also introduced as a bio-surfactant to reduce the charge transfer obstacle between the microbes and the electrodes. The surface morphology illustrated that the strain had a plump shape with a high specific area. Accordingly, bio-surfactant addition promoted the anode biomass (1.2 ± 0.1 mg/cm2to 1.7 ± 0.2 mg/cm2) and achieved a higher degradation rate (68% ± 4%). The feasibility of electrochemical disposal on pyridine and eminent adaptability of strain sp. HR-1 as a Gram-positive exoelectrogen makes MFC a practical approach for real application.Keywords:microbial fuel cells;gram-positive exoelectrogen;pyridine;trehalose lipid;Rhodococcus pyridinivorans
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高影响因子
Polymers
·
2023
·Vol. 15
·期 4
·810
·
IF 5
Zeping Wang,Binjie Hu,Haibin Yu,George Zheng Chen
In this study, three copolymers of poly(methyl methacrylate) and poly(butyl acrylate) (PMMA-co-PBA) latex containing 1-octyl-3 methylimidazolium hexafluorophosphate (C8mimPF6), cellulose nanocrystals (CNCs), and C8mimPF6-CNCs were successfully synthesized through mini emulsion polymerization. These novel composites were each coated on mild steel panels and tested for their anti-corrosion performance by immersion of the coated samples in 3.5 wt% sodium chloride (NaCl) solution over a certain period. The synergistic anti-corrosion effects of the C8mimPF6-CNCs sample led to the highest coating resistance, charge transfer resistance, and corrosion inhibition efficiency and the lowest diffusion coefficient and corrosion rate. The proposed synergistic mechanism revealed that CNCs enhanced the barrier effect of the coating while C8mimPF6inhibited corrosion when released.Keywords:ionic liquid;cellulose nanocrystals;corrosion protection;polymer;electrochemical analysis;composite
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2023
·
IF 6.1
Dingkai Wang,Mingyu Cui,Yanjun Li,Wei Zhao,Shangshang Ma,Zhijie Jiang,Xutang Liu,Chong Liang,Rujuan Li,Long Ma,Yanmin Song,Xian-Yong Wei
The facile, green, and efficient strategy for the separation of lignin from straw and subsequent production of value-added chemicals is crucial to the current utilization of straw. Herein, up to 23.72% of lignin was isolated from wheat stalk over cheap and green 1-(3-sulfobutyl) triethylammonium hydrogen sulfate ([BSTEA]HSO4) in aqueous ethanol (Vethanol: Vwater = 4:1). The acquired lignin was verified as a p-hydroxyphenyl-guaiacyl-syringyl type, which had a narrower molecular weight distribution, better thermal stability, and higher purity compared with those of the lignin obtained using 1-methyl-3-(4-sulfobutyl)-imidazolium hydrogen sulfate and 1-(3-sulfobutyl) pyridinium hydrogen sulfate. Moreover, a carbohydrate-rich liquid containing [BSTEA]HSO4 was obtained by water removal from the waste liquid after lignin separation and further converted to ethyl levulinate (EL) by a one-pot process in the presence of inexpensive and stable USY zeolite. The yield of EL reached 30.23% at 200 °C for 60 min over the presence of 40% [BSTEA]HSO4 and 60% USY zeolite. Under optimal conditions, the yields of lignin and EL can respectively reach 83.89 and 72.28% of those catalyzed by a fresh catalyst after five cycles. In short, the above-mentioned methods present a green, economic, and efficient route for the extraction of lignin and further treatment of the liquid waste generated during the extraction process.
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高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2023
·
IF 6
Yongdi He,Jinou Song,Jiuzhong Yang,Yuan Zhuang,Liang Qiu,Zhijun Li,Shubao Song,Jibiao Xie
An experimental study of 5% 1 -nitropropane (1-NP)-initiated cyclohexane pyrolysis was carried out in a flow reactor at 30 Torr (4.0 kPa) over a temperature range of 673–1273 K. The pyrolysis species were detected with synchrotron vacuum ultraviolet photoionization mass spectrometry (SVUV-PIMS) technique. Pyrolysis species from m/z 15–106, including C 1 -C 8 hydrocarbons, CO, NO, NO 2 , CH 2 O, CH 3 OH and C 3 H 5 NO, were identified with near-threshold photoionization efficiency (PIE) spectra and quantified at different temperatures. The experimental results indicated that the addition of 1-NP obviously reduced the initial pyrolysis temperature of cyclohexane from 1048 to 1098–723 K, and caused the decreases of the initial formation temperatures for the species from cyclohexane pyrolysis. Almost all the high-temperature pyrolysis species in the mechanisms proposed in the literature were identified in the experiments. Based on the experimental results in this work and rate coefficients proposed in the literature, the primary pyrolysis mechanisms of cyclohexane in the presence of 1-NP were discussed. The 1-NP pyrolysis occurs at a lower temperature than the cyclohexane does, and produces HONO, NO 2 , C 3 H 7 , etc. It was demonstrated that cyclohexane was mainly consumed via the H-atom abstractions by H and OH attacks in this work and the cyclohexyl radical formed via H-atom abstractions mainly isomerized into 1-C 6 H 11 -6 radical, which further combines with H to form 1-C 6 H 12 .
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高影响因子
Frontiers in Pharmacology
·
2022
·
IF 5.988
Xiao Man,Chen Bocen,Niu Kun,Long Ziyu,Yang Fan,Xie Yiqiang
Background: Alpiniae Oxyphylla Fructus (AOF) is Traditional Chinese medicine and a dietary supplements for centuries, which posseses cardiotonic, neuroprotective, antioxidant, warming the kidney and nourish the spleen, these biological fuction is related to potential anti-aging properties. However, little is known about their effects on aging. This work aimed to investigate the effects of extracts of AOF on longevity and stress resistance in Caenorhabditis elegans (C. elegans) and the mechanisms that underlie its effects.Methods: Wild-type (WT) strand of C.elegans (N2)worms were cultured in growth medium with or without AOF. First, we examined the effects of AOF on lifespan, reproduction and healthspan assay, stress resistance and oxidative analysis, lipofuscin levels. Second, The levels of ROS and MDA, the antioxidant enzyme activities were examined to explore the underlying mechanism of AOF. Finally, the expression of the longevity-related genes were investigated to further understand the AOF’s underlying mechanism.Results: The lifespan of C. elegans was prolonged by 23.44% after treatment with high-dose AOF (100 ug/ml). AOF alleviated aging-related declines in C. elegans health and enhanced resistance to heat shock. Furthermore, AOF decreased reactive oxygen species and malondialdehyde, increased the activities of superoxide dismutase and catalase, and reduced accumulation of fat. AOF upregulated the expression of sod-3, gst-4, daf-16, and skn-1 but downregulated the expression of daf-2 and age-1 and accelerated the translocation of DAF-16 into the nucleus. The extended lifespan induced by AOF was reversed in daf-16(mu86) and skn-1(zu135) mutants, indicating that this gene is involved in AOF-regulated longevity.Conclusion: Our findings demonstrated that AOF extends lifespan and healthspan and enhances stress via boosting the activity of the antioxidant enzyme and controlling the expression of genes associated with insulin/IGF signaling and SKN-1 pathways. As a result, this work suggested AOF as a possible candidate to reduce the signs of aging by activating and inhibiting target genes.
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高影响因子
JOURNAL OF CATALYSIS
·
2023
·
IF 7.3
Zijun Yang,Qiang Yu,Hua Wang,Qingfeng Ge,Xinli Zhu
Ketonization of propionic acid has been investigated on Lewis acidic TS-1 and Ti-Beta zeolites to understand the reaction mechanism and effects of pore topology and hydrophobicity. Characterizations showed that TS-1 and Ti-Beta (Si/Ti = 40) exhibited a similar acidity whereas TS-1 was more hydrophobic than the silanol-rich Ti-Beta. TS-1 showed higher activity, selectivity, stability and was more resistance to H 2 O than Ti-Beta. A combination of infrared spectroscopic, isotopic and kinetic studies showed that the molecularly adsorbed monodentate propionic acid is the most abundant reactive intermediate, and C-C coupling is the rate-determining step. The mechanism of ketonization of propionic acid at isolated tetrahedral Ti centers can be described by a Langmuir-Hinshelwood model. The turnover rate on TS-1-40 is ∼ 1.3 times higher than that on Ti-Beta-40, which is consistent with the lower fitted free activation energy, i.e., the energy difference between C-C coupling transition state and two co-adsorbed propionic acids at a Ti center. The slightly lower activation enthalpy on Ti-Beta-40 than TS-1-40 is over-compensated by much larger entropy penalty, due to more silanol groups and hydrogen bonded propionic acids in close proximity to the Ti center for Ti-Beta-40, which impose additional steric hindrance to bulkier C-C coupling complex at transition state and outweigh the difference of steric hindrance of pore confinement between MFI and BEA frameworks. This work provides insight into the ketonization mechanism on Lewis acidic zeolites, and indicates that moderate pore size with hydrophobic property promotes ketonization of carboxylic acid at isolated tetrahedral Ti centers confined in zeolites.
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高影响因子
IONICS
·
2023
·Vol. 29
·期 9
·3795-3803
·
IF 2.8
Xiong Qinghao,Wan Haifei,Peng Xia,Zhu Yongmei
N-rich carbon (C) microspheres loaded with Ni nanoparticle (NiNP) microspheres (Ni@N-doped C) were obtained by calcination of covalent organic framework (COF) LZU-1 with abundant N atoms/Ni 2+ . Lots of NiNPs with the size of 4 nm are arrayed uniformly and firmly into N-doped C microspheres derived from COF LZU-1 based on the strong coordination between N atoms on the wall of well-ordered pores and Ni atoms, which is more beneficial to rapid electron and mass transfer. The synergistic effect from N-doped C microspheres and small-sized NiNPs in Ni@N-doped C enhances catalytic activity of Ni@N-doped C microspheres greatly, which provides feasibility for the construction of non-enzymatic electrochemical sensor. The non-enzymatic electrochemical sensor based on Ni@N-doped C microspheres is applied to the detection of dopamine (DA) and shows good detection results with a low detection limit of 0.009 μM and a wide detection range of 0.027–70 μM. What is more, this DA sensor has good anti-interference, reproducibility, and stability, which provides new idea for the construction of non-enzymatic electrochemical sensor.
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