Canadian Journal of Chemistry
·
2022
·Vol. 100
·期 6
·
IF 1.051
Junyong Sun,Xian Liu,Like Chen,Lijun Peng,Xitian Peng,Tian Gan
Herein, polyvinylpyrrolidone-stabilized Au nanorods were controllably implanted into ZIF-8 to form a well-uniformed AuNRs@ZIF-8 electrocatalyst with a multicore-shell structure. After characterizing the chemical and physical properties, a novel electrochemical sensing platform was fabricated for 2-chlorophenol (2-CP) monitoring based on the AuNRs@ZIF-8 modified glassy carbon electrode. Due to the unique electrochemical property of AuNRs cores and ultra-porous architecture of ZIF-8 shell, the electrocatalyst would effectively accelerate the electron transfer and greatly improve the electrochemical response of 2-CP. Under the optimized experimental conditions, the oxidation peak current of 2-CP enhanced linearly with the increase of its concentration between 0.010 and 40 μM, and the limit of detection was 3.6 nM based on S/N = 3. Meanwhile, the prepared AuNRs@ZIF-8 electrode showed favorable stability, reproducibility, and selectivity, which could be applied to the accurate analysis of 2-CP in aquaculture with standard addition recovery ranging from 96.67% to 104.0%.
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高影响因子
Materialia
·
2022
·
IF 0
Jianfeng Yang,Qingling Zhao,Zehao Zang,Shuquan Zhang,Ziwu Wang,Lanlan Li,Xiaofei Yu,Xiaojing Yang,Zunming Lu,Xinghua Zhang
Magnetic resonance imaging (MRI) contrast agents with high relaxivity is of great importance for clinical diagnosis. Here we propose an effective method to enhance the relaxivity of MRI contrast agents. Ultra-small gadolinium oxide nanoparticles (Gd 2 O 3 NPs) with different surface ligands were prepared by coprecipitation method, and the polyacrylic acid (PAA) modulated Gd 2 O 3 NPs (PAA-Gd 2 O 3 ) have the high r 1 relaxivity of 53.34 mM –1 s –1 , which is mainly induced by the strong affinity between PAA and water molecules. In addition, PAA modulated Gd 2 O 3 NPs were successfully loaded on Au@MSNs (Au nanorod coated with mesoporous silica , Gd 2 O 3 /Au@MSNs) with enhanced affinity between Gd 3+ and water molecules, as well as increased motional time of Gd 3+ . Therefore, the r 1 relaxivity of Gd 2 O 3 /Au@MSNs can be up to 64.53 mM –1 s –1 , which is 17 times of the commercial agent Gd-DTPA. The Gd 2 O 3 /Au@MSNs NPs also have a low r 2 /r 1 of 1.04 and good computed tomography (CT) imaging performance, as well as good biocomatibility, which have great potential applications in multimodal bioimaging.
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ANALYST
·
2020
·Vol. 145
·期 16
·5500-5507
·
IF 3.978
Wene Liu,Lili Tian,Jie Du,Jiangmin Wu,Yongmei Liu,Guofan Wu,Xiaoquan Lu
Developing a rapid, low-cost, and multimode detection method for heavy metal ions remains a compelling goal for many applications, including food safety, environmental and biological analysis. This study investigated the influence of Hg2+ on the peroxidase-like activity of gold nanoparticles (GNPs) decorated on carbon dots (CDs) from lysine (denoted as GNP@CDs). A new type of Hg2+-triggered peroxidase-like activity of GNP@CDs was discovered, which could catalyze the oxidation of the colorless 3,3′,5,5′-tetramethylbenzidine (TMB) into blue TMB. Based on the regulation of the catalytically triggered activity, a sensitive colorimetric method for the detection of Hg2+ was developed, with a linear range of 7–150 nM, providing a limit of detection as low as 3.7 nM. The sensor is simple and rapid, and was successfully applied to the detection of Hg2+ enrichment in chlorella, suggesting a promising application in biological analysis.
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高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Wenda Wang,Zhenting Zhao,Qian Lei,Hongyan Xu,Jie Hu,Lin Chen
A highly sensitive gold nanoparticles (AuNPs) functionalized hierarchical layered NiCo 2 O 4 nanosheets/NiCo 2 O 4 nanowires (NCSs/NCWs) core–shell structures is proposed toward hydrazine detection using hydrothermal and electrodeposition methods. Various techniques were used to investigate the morphology, crystalline structure and chemical compositions of as-synthesized AuNPs@NCSs/NCWSs sample. The electrochemical performances of the as-prepared hydrazine sensors were evaluated by optimization different experimental parameters including growth time of nanowire and electrodeposition time of AuNPs. The as-proposed AuNPs-180@NCSs/NCWSs hydrazine sensor exhibits excellent electrochemical properties to hydrazine detection, including high sensitivity (14.36 μA·μM −1 ·cm −2 ), good linear range (0.8–499.8 μM), low detection limit (0.23 μM) and superior performance for real sample determine, which can be ascribed to the synergistic effects between the NiCo 2 O 4 nanosheets/NiCo 2 O 4 nanowires core–shell arrayed structures and AuNPs. Therefore, the as-synthesized hierarchical layered double NiCo oxide/core–shell nanostructure is a promising candidate for the highly sensitive sensing material of the electrochemical sensor.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Sitong Feng,Lingchu Huang,Qi Lu,Tong Wang,Rui Han,Xiaoyong Sun,Xishuang Liang,Fengmin Liu,Fangmeng Liu,Geyu Lu
The fuel cell type gas sensor has attracted wide attention due to its advantages of operating at room temperature, low power consumption and good stability. In this study, a new sensitive electrode material Au-Ni/CF was developed for the detection of NO 2 . Through XRD , SEM and TEM characterization, it has been demonstrated that the electrode material exhibits improved crystallinity after being sintered at high temperatures. This leads to a reduction in charge transfer impedance. Additionally, XPS testing and TEM characterization have confirmed that high temperature sintering results in the reduction of more metal elements, leading to an increase in the electrochemical surface area and effectively improving sensor sensitivity. Furthermore, adjusting the mass ratio of gold to nickel can alter the surface lattice arrangement and electronic structure of the electrode material, subsequently impacting its resistance and catalytic ability towards NO 2 , ultimately enhancing sensor sensitivity. The sensitivity of the sensor using Au 5 Ni 2 /CF as the electrode material for detecting 0.05–10 ppm NO 2 was found to be 47.88 nA/ppm with response and recovery times of 35 s and 25 s respectively when exposed to 2 ppm NO 2 . Furthermore, it exhibited good selectivity and stability, indicating promising potential for application in room temperature atmospheric environment monitoring.
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yifan Liu,Yiyu Yang,Minjie Peng,Wen Zang,Chaozhen Wang,Yuenan Zhang,Changyong Gao,Aiguo Wu,Yujie Zhang
Heparin, as a glycosaminoglycan with multiple physiological functions, performs important roles in clinical practice. The core function of heparin is its anticoagulant effect, which is commonly used to prevent and treat thrombotic diseases. However, when the heparin content in human blood exceeds the standard, it can result in thrombocytopenia, thereby posing threat to human health. Therefore, rapid, sensitive and accurate detection of heparin is of great practical importance in assessing the anticoagulant effect, prevention of thrombophilia, guidance on personalized medication, and avoiding side effects caused by excessive use. A new colorimetric sensor for detecting the anticoagulant heparin is introduced in this work. The sensor is low cost, fast, and simple. In the absence of heparin, protamine protects copper‑gold nanoparticles from the etching of iodide ions through electrostatic interaction, and the solution's color and spectral properties remain essentially the same as those of pure copper‑gold nanoparticles. When heparin is present, due to the strong electrostatic adsorption between heparin and protamine, protamine preferentially binds heparin and forms a complex. Cu-Au NPs are not protected and are etched into spherical Au NPs by iodide ions. The solution's color shifted from dark gray and purple to pink, thus colorimetric detection of heparin is realized rapidly based on the etching mechanism. The detection time is 15 min, and the detection limit is as low as 1 ng/mL. Compared with HPLC detection method, the colorimetric detection of heparin in serum samples has the recovery rate of 98.8–108.8 %, which has good prospects for application.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Ye Wang,Yulong Ying,Lvlv Ji,Wei Li,Yuan Wei,Tao Wang,Sheng Wang
The concurrent generation of clean hydrogen fuel and value-added organic compounds through photocatalysis offers a promising pathway for solar-to-chemical conversion. Here, we present a ternary Au-mediated S-scheme heterostructure comprising hollow TiO 2 nanobowls (HTNB), vertically aligned ZnIn 2 S 4 (ZIS) nanosheets, and interfacially confined Au nanoparticles. The hollow TiO 2 scaffold, fabricated via a green and scalable electrospray method, shortens carrier diffusion paths, while the direct S-scheme junction preserves strong redox potentials. Embedded Au nanoparticles at the HTNB/ZIS interface act as directional electron mediators, enabling cascade charge transfer (TiO 2 → Au → ZIS) and suppressing recombination. The optimized HTNB/Au@ZIS achieves a remarkable H 2 evolution rate of 42.27 mmol g −1 h −1 with an apparent quantum efficiency of 59.5 % at 380 nm under simulated solar light, among the highest reported for TiO 2 /ZIS systems. In a sacrificial-free system, it simultaneously produces 4.48 mmol g −1 h −1 H 2 and 4.05 mmol g −1 h −1 N-benzylidenebenzylamine with > 99 % selectivity. Comprehensive spectroscopic, electrochemical, and EPR analyses confirm the Au-mediated S-scheme charge-transfer mechanism. This work demonstrates a generalizable interfacial-engineering strategy for coupling oxidative and reductive photocatalysis, advancing the design of efficient dual-functional photocatalysts for solar-to-chemical energy conversion.
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高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Qian Lan Li,Da Yong Miao,Zhong Wei Jiang,Kun Lin Huang,Chang Xia,Yi Wang
Dark-field microscopy (DFM) as a single particle analysis (SPA) technique has been developed rapidly in recent years because of its high signal-to-noise ratio, enhanced sensitivity, and sufficient spatial and temporal resolution. Here, an in situ single Au@Cu2O core–shell nanoparticle (Au@Cu2O NP) light scattering imaging analysis was reported to realize the ultrasensitive detection of biothiols–cysteine (Cys) and glutathione (GSH). Based on the specific binding of Cu(I) with –SH to the formation of the Cu–S bond, it triggered the decomposition of the Cu2O shell and exposure of the Au nanorods (Au NRs) in the presence of biothiols. Moreover, the process of Cu2O shell dissolution has been observed in real time under DFM, which indicated that the scattering color changed from bright green to dark red and the scattering intensity decreased, correspondingly. Compared with ex situ SPA, in situ SPA exhibited significantly high sensitivity due to the effect of concentration polarization, which exhibited linear correlations over broad concentration ranges (Cys: 0.05–3 nM, GSH: 0.1–10 nM), with low detection limits of 15.52 pM (Cys) and 75.07 pM (GSH). Therefore, this work provides a smart strategy to find promising applications for the ultrasensitive detection of biomolecules through SPA.
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Ying Zhou,Senfeng Liu,Xinlei Yan,Yunying Wei,Liang Ma,Ruo Yuan
The convenient detection of tetracycline (TC) residues has attracted considerable attention because irrational use of TC causes food pollution damaging the human health. Herein, a point-of-care testing (POCT) platform is established for the sensitive and specific determination of TC in a polydopamine-functionalised Eppendorf tube. In particular, TC can be efficiently recognised by an aptamer–antibody chimera to trigger visual fluorescence (FL) and electrochemiluminescence (ECL) ‘dual-signal’ response of gold nanoclusters. Consequently, the biosensor exhibits a wide detection range spanning from 5 fM to 1 μM, with low detection limits of 73 fM (visual FL) and 2.3 fM (ECL). Hence, it can be said that the POCT platform is superior to the enzyme-linked immunosorbent assay. The strategy utilises the strength of FL, i.e. visualisation, and that of ECL, i.e. high sensitivity, providing a guiding approach for the development of POCT in food security and environmental monitoring.
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PubMed
高影响因子
HYDROMETALLURGY
·
2025
·
IF 5.3
Feng Feng,Heda Ding,Jiaying Zhang,Lu Yu,Yuxue Yue,Yanxia Sun,Lingling Guo,Xiaoliang Xu,Chunshan Lu,Qunfeng Zhang,Xiaonian Li
The development of industrial technology has significantly promoted the production and accumulation of spent precious metal-based catalysts. This work describes the synthesis of an ionic liquid – [BIim][Cl 3 ] and its application as an alternative to toxic and corrosive reagents for precious metal leaching from waste catalysts. The leaching process using [BIim][Cl 3 ] is proved to be safe and green. It offers a higher stability and higher leaching efficiency compared to other reagents used in previous publications. The ionic liquid [BIim][Cl 3 ] enabled the efficient leaching of Pd and Au, as well as the extremely stable precious metals Pt, Rh under mild conditions. The highest leaching efficiencies achieved by [BIim][Cl 3 ] were 99.9 %, 98.5 %, 98.6 % and 90.6 % for Pd, Au, Pt and Rh under the optimal leaching conditions, respectively. In order to reveal the leaching mechanism, XPS, far infrared (FIR), NMR, and EDS were used to demonstrate the importance of imidazolium cations in the leaching process. The leaching pathway was proposed based on the DFT calculation results on transition state energy barrier.
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高影响因子
BIOMATERIALS
·
2025
·
IF 12.9
Yuchao Sun,Jian He,Weiyu Chen,Yongfang Wang,Kai Wang,Min Zhou,Yichun Zheng
High-dose radiation therapy is a widely used clinical strategy to inhibit tumor growth. However, the rapid generation of excessive reactive oxygen species (ROS) triggers the formation of neutrophil extracellular traps (NETs), which capture free tumor cells in the bloodstream, promoting metastasis. In this study, we developed a hybrid nanoparticle composed of DNase I and gold (DNase I@Au) to enhance radiotherapy efficacy while mitigating metastasis by precisely eliminating NETs. The DNase I@Au nanoparticles, administered via aerosol inhalation, are efficiently delivered to lung tumor tissue, improving radiosensitization and reducing tumor size. Crucially, the nanoparticles could gradually release DNase I, effectively degrading ROS-induced NETs and preventing the interaction of free malignant cells with tumor sites or vasculature, thereby inhibiting metastasis. Therefore, we provide an enzyme and sensitizer co-loaded strategy that offers a promising approach to improve the therapeutic outcome of radiotherapy and reduce the risk of lung cancer metastasis under ROS stimulation.
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DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2017
·
IF 4.95
Yi Wang,Yang Zeng,Wensheng Fu,Pu Zhang,Ling Li,Cuiying Ye,Lan Yu,Xiaochun Zhu,Song Zhao
Seed-mediated growth has been employed as a simple and powerful means to the shape-controlled synthesis of metal nanocrystals . In this work, we apply the principle of seed-mediated growth in analytical chemistry , and achieve improved sensitivity due to the low energy barrier in the target-induced formation of bimetallic nanoparticles with core-shell structure. As a result, a simple, reliable, highly sensitive and selective method for the detection of ellagic acid (EA), a naturally occurring polyphenolic antioxidant , has been developed. With the aid of EA in alkaline solution, Ag + ions can be transformed to Ag atoms and deposit on the surfaces of Au nanorods (AuNRs, act as seeds here) to generate Au@Ag core-shell nanorods, accompanied by blue shift of the longitudinal localized surface plasmon resonance (LSPR) band of AuNRs from near-infrared region to shorter wavelengths. Based on the linear relationship between the wavelength change of longitudinal LSPR band and the concentration of EA, our method achieves a detectable range of 0.2–20 μM and a limit of detection as low as 40 nM toward EA. This approach is highlighted by its high sensitivity for EA assay, which benefits from the viewpoint of thermodynamics in the nucleation/growth mode of metal nanoparticles. Moreover, this method shows high selectivity for EA detection when potential species coexist, and thus has been successfully applied in the detection of EA in skin-whitening cosmetics. The proposed strategy of seed-mediated growth herein can also be extended to other systems for sensing.
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PubMed
高影响因子
危险品化学品经营许可证（带存储）