Journal of CO2 Utilization
·
2022
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IF 8.321
Jiqing Dong,Ran Ping,Xun Dai,Dongchao Wang,Fusheng Liu,Shanshan Du,Mengshuai Liu
The combination of pyrrolidine-2,5-dione-derived ionic liquids with silver acetate (AgOAc) were developed as binary catalysts for conversion of simulated flue gas CO 2 and propargylic alcohols to α-alkylidene cyclic carbonates . By tuning different catalyst components, the [HTMG][Pyrro]/AgOAc system was confirmed to be the most efficient and exhibited an excellent synergistic action in facilitating the carboxylic cyclization under room temperature and solvent-free conditions. The influence of reaction parameters on carboxylic cyclization of CO 2 with 2-methylbut-3-yn-2-ol were optimized. Under the determined conditions, the [HTMG][Pyrro]/AgOAc system was stable enough to show durable high activity in eight recycles, and also versatile in carboxylic cyclization of flue gas CO 2 with other propargylic alcohols. Moreover, a thorough comparison of [HTMG][Pyrro]/AgOAc with the reported catalysts was provided and evaluated, the results suggested that the developed catalytic system has significant advantages in practical application. Finally, the mechanistic details for the conversion of CO 2 into α-alkylidene cyclic carbonates catalyzed by [HTMG][Pyrro]/AgOAc was also elucidated on the basis of reactants activation.
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METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
·
2023
·Vol. 54
·期 2
·712-733
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IF 3
Zhang Xi,Na Hao,Liu Pengyao,Wang Yajun,Li Junguo,Meng Qian,Li Guopeng
Regulating the phase transformation of γ → β in dicalcium silicate (C 2 S) can effectively improve the hydration activity and recycling rate of AOD slag; however, the evolution law for γ → β in C 2 S has not been extensively investigated. In this study, a novel “two-step” γ → α ′ L → β phase transformation method in C 2 S was designed based on the study of the pure C 2 S phase at a nonequilibrium state in the low- and middle-temperature ranges. The “two-step” method can be used to realize the transformation from needle-like nanostructured γ -C 2 S grains to lamellar-structured β -C 2 S grains, exhibiting the trend of interlaminar peeling accompanied by expansion of the particle volume and leading to the appearance of macroscopic lamellar cracking in β -C 2 S particles. In addition, the β -C 2 S mass fraction in AOD slag treated by water cooling at 680 °C reaches a maximum value of 47.5 wt pct, while the treated AOD slag presents abundant holes and defects, which can effectively enlarge the hydration contact area.
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CRYSTENGCOMM
·
2022
·Vol. 24
·期 21
·3852-3858
·
IF 3.756
Runze Guo,Yufeng Liu,Yongzheng Fang,Zhifu Liu,Langping Dong,Lei Wang,Wenyao Li,Jingshan Hou
CsPbI3 has the least chemical stability among the CsPbX3 (X = Cl, Br, and I) perovskite nanocrystal (PNC) family due to its thermodynamically metastable characteristics, thus limiting the development of all-inorganic perovskite white-light devices. The current study presents a microfluidic-based continuous large-scale fabrication of CsPbI3-mesoporous SiO2 (CPI/m-SiO2) nanocomposites to solve the problem of large-scale continuous production of stable, repeatable, high-quality perovskite NCs. The results reveal that the chemical stability and thermal quenching behaviour of CPI PNCs were greatly improved due to the protection of mesoporous silica. Particularly, the water resistance property of CPI/m-SiO2 nanocomposites improved two-fold compared to that of noncomposite CPI PNCs, and the thermal stability of the CPI/m-SiO2 nanocomposites improved nearly three-fold at 373 K when compared with that of the noncomposite CPI NCs. Furthermore, photons were speculated to transmit along with the pores and channel structure of m-SiO2 to reduce photon absorption between NCs. Moreover, the microfluidic technology can operate continuously and is precisely controllable, enabling large-scale nanocomposite synthesis with uniform size and shape.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Xufei Li,Yanling Qiu,Zhiliang Zhu,Ting Chen,Hua Zhang,Daqiang Yin
Insufficient photocatalytic activity and poor recyclability are considered as two main factors that limit the further application of photocatalysts in environmental remediation. Herein, a new magnetic g-C 3 N 4 /α-Fe 2 O 3 /Bi 3 TaO 7 (CN/FO/BTO) heterojunction with dual Z-scheme system was first synthesized via an ultrasound-assisted calcination process. The results showed that the removal efficiency of ciprofloxacin (CIP) by optimized CN/FO/BTO heterojunction could reach 95.6% within 120 min illumination of visible light, which was 6.1, 15.9, 5.2, 3.7 and 2.3 times as much as that of single CN, FO, BTO, binary CN/FO and CN/BTO, respectively. Characterization analysis indicated that the improved photocatalytic activity derived from the synergistic effects of the three components, including the dispersion of FO and BTO by CN sheet, the enhanced light absorption of CN by addition of FO and BTO, and the reduced photogenerated charge recombination by their intimate contact. Further mechanism study revealed that the dual Z-scheme system of CN/FO/BTO leaded to efficient photoexcited carrier separation and strong redox capacity, in which •O 2 – and •OH were main radicals during photocatalytic process. Meanwhile, CN/FO/BTO possessed supreme adaptability to pH as well as co-existing matters, favorable magnetic separation property and excellent stability, making it a potential candidate for environmental remediation applications.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Bin Hu,An-shuai Cheng,Yang Li,Yao-bing Huang,Ji Liu,Bing Zhang,Kai Li,Li Zhao,Ti-peng Wang,Qiang Lu
Selective preparation of value-added products via fast pyrolysis is a sustainable way for biomass utilization. We developed a novel strategy, oxalic acid-assisted fast pyrolysis (OAFP) of cellulose, which achieved the selective production of a promising anhydrosugar, 1,4:3,6-dianhydro-α- d -glucopyranose (DGP), for the first time. Effects of temperature and the mass ratio of cellulose-to-oxalic acid (Cell/OA) in their solid mixture were explored. The yield of DGP could be up to 14.0 wt% (based on cellulose) at 400 °C and the Cell/OA mass ratio of 1:9 with a lab-scale setup, about 200 times higher than that from fast pyrolysis of pure cellulose. According to the experiments and density functional theory (DFT) calculations, it was OA rather than its pyrolysis vapors (mainly formic acid) that played the predominant role in the selective generation of DGP, where OA acted as a reactant and a catalyst-like material at the same time. The formation of DGP competed with that of levoglucosan (LG), the most typical product in the fast pyrolysis of pure cellulose, and a small amount of DGP came from the secondary conversion of LG. The esterification of free hydroxyl at C3 or C6 position with OA determined the selective generation of DGP by promoting the formation of the C1 = C2 bond and the 3,6-acetal ring, and the generation of the 1,6-acetal ring was inhibited correspondingly which led to the decrease of LG. In addition, the OAFP process also showed the potential for poly-generation of value-added chemicals, syngas, and char.
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2022
·
IF 6.364
Zhaowen Ren,Wancheng Zhou,Yuchang Qing,Hui Xie,Shichang Duan,Haijun Pan,Xiaoke Lu,Xia Chai,Di Ran,Yingze Zheng
The Al and H 3 BO 3 mixed powder was introduced into the PCS/Xylene precursor solution as in-situ synthesis α-Al 2 O 3 filler by precursor infiltration and pyrolysis (PIP) method. The in-situ synthesis filler can effectively decrease the open porosity of SiC f /SiC composites and give rise to multiple scattering of microwave and dipolar polarization. Therefore, the mechanical and microwave absorption properties of SiC f /SiC composites can be simultaneously enhanced. The effects of in-situ synthesis filler on the morphologies, flexure strength and reflection loss values of SiC f /SiC composites were investigated. With 2 wt% in-situ synthesis filler, the flexure strength of SiC f /SiC composite was 305 MPa and the maximum reflection loss ( RL m ) can reach − 54.68 dB with the effective absorption band (EAB) of 3.51 GHz in the X band. With 5 wt% in-situ synthesis filler, the flexure strength of SiC f /SiC composite was 207 MPa and the RL m was − 30.91 dB. Due to the inefficient infiltration process, the RL m of SiC f /SiC composites with 10 wt% in-situ synthesis filler was only − 27.36 dB. Nevertheless, the flexure strength of that composite was 259 MPa, owing to the dense matrix. Additionally, the flexure strength of SiC f /SiC composite without filler was 148 MPa and the RL m was − 26.40 dB.
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POLYHEDRON
·
2022
·
IF 2.975
Chunqing Wang,Na Xia,Siming Zhu,Lin Chen,Liang Chen,Zhendong Wang
In this study, α- l -rhamnosidase was immobilized on magnetic Fe 3 O 4 /MIL-101 (Cr) nanoparticles using MIL-101(Cr) as precursor by crosslinking method. The crosslinking agent concentration ratio and crosslinking time were EDC/NHS 1:1 and 2 h, respectively. The immobilized materials were characterized by FT-IR, XRD, SEM and VSM. The saturation magnetization of the prepared magnetic nanoparticles was 46.2 emu/g. The optimum pH and temperature of immobilized enzyme were 6 and 60 °C. The application of immobilized enzyme in the preparation of hesperidin dihydrochalcone glucoside (HMGDC) by hydrolysis of hesperidin dihydrochalcone (HSDDC) was studied. The results showed that immobilized enzyme had better temperature resistance, repeatability and stability than free enzyme. The immobilized enzyme activity was 293.55 U/g, and the recovery was 116.03%. After treatment at 60 °C for 4 days, the enzyme activity remained at 24.6%. The conversion rate of HSDDC reached 93.1%.
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PROCESS BIOCHEMISTRY
·
2022
·
IF 4.885
Lingling Han,Jiaqi Song,Chaoqun Yan,Chunqiang Wang,Liwei Wang,Wen Li,Yan Du,Qingshan Li,Taigang Liang
Inhibition of α-glucosidase activity plays a key role in reducing blood glucose level of type Ⅱ diabetic patients. In study, the inhibitory activity and mechanism of Calycosin (CA) and calycosin-7- O -β- D -glucoside (CAG), active components from Astragalus membranaceus , against α-glucosidase were studied by α-glucosidase activity tests, spectral analysis and docking simulation studies. The results suggested that the α-glucosidase inhibitory activity of CA (IC 50 =39.45 μM) and CAG (IC 50 =174.04 μM) were superior to acarbose (positive drug, IC 50 =471.73 μM). Fluorescence data indicated that CA and CAG quenched the fluorescence of α-glucosidase by spontaneous forming CA-α-glucosidase and CAG-α-glucosidase complexes. Besides, results obtained from CD and FT-IR analysis showed that the binding of CA or CAG to α-glucosidase caused conformational changes of α-glucosidase. Docking simulation results further suggested that, compared with CAG, CA had higher affinity for α-glucosidase because of its tightly bound to residues in active cavity of α-glucosidase. These findings demonstrated the α-glucosidase inhibitory activity and mechanism of CA and CAG, moreover, provided the basis for structural modification of AM flavonoids in the treatment of diabetes mellitus.
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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
·
2022
·
IF 5.112
Ping Zhu,Ling Cai,Qiao Liu,Shanwu Feng,Hongjie Ruan,Li Zhang,Liuzhu Zhou,Huijun Jiang,Hongsheng Wang,Jianming Wang,Jin Chen
Nowadays, pathogenic infection has posed a severe threat to the public health and environmental sanitation, urging a continuous search of efficacious and safe bactericidal agents of various formulated forms. Here, a facile one-pot hydrothermal preparation of mesoporous silica nanoparticles using ultrasonication-assisted nanoemulsion of α-Linolenic acid (α-LA) as template was developed. The formed silica mesocomposite at water/fatty-acid surface provides an easy yet green synthesis route, which can be generalized for the further encapsulation of hydrophobic drugs such as antimycobacterial Rifampicin (RIF). The obtained α-LA nanoemulsion-templated silica nanoparticles (LNS NPs), with a weight content of ∼17% α-LA in the composite, showed apparent antibacterial effect against Staphylococcus aureus ( S. aureus ). By comparison, the removal of α-LA from the silica nanoparticles (LNS-1 NPs) resulted in the composite of enlarged pore size with negligible bactericidal activities. Notably, the Isoniazide (INH) and Rifampicin (RIF)-encapsulated LNS NPs exhibited outstanding antimycobacterial activity against both drug-sensitive and drug-resistant Mycobacterium tuberculosis ( M. tuberculosis ). The obtained highly biocompatible, biosafe and low-energy consumptive α-LA-contained mesostructured silica-based bactericide holds promising therapeutic potentials to tackle the emerging drug-resistant infectious microbes.
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PubMed
高影响因子
DRUG DELIVERY
·
2021
·
IF 6.419
Jianbo Li,Tiange Feng,Weijing Yang,Yaru Xu,Shuaishuai Wang,Huijie Cai,Zhilei Liu,Hong Qiang,Jinjie Zhang
Although Fraxinellone (Frax) isolated from Dictamnus albus L. possessed excellent anti-hepatic fibrosis activity, oral administration of Frax suffered from the inefficient therapeutic outcome in vivo due to negligible oral absorption. At present, the oral formulation of Frax is rarely exploited. For rational formulation design, we evaluated preabsorption risks of Frax and found that Frax was rather stable while poorly dissolved in the gastrointestinal tract (78.88 μg/mL), which predominantly limited its oral absorption. Further solubility test revealed the outstanding capacity of cyclodextrin derivatives (CDs) to solubilize Frax (6.8–12.8 mg/mL). This led us to study the inclusion complexes of Frax with a series of CDs and holistically explore their drug delivery performance. Characterization techniques involving 1H-NMR, FT-IR, DSC, PXRD, and molecular docking confirmed the most stable binding interactions when Frax complexed with 6-O-α-D-maltosyl-β-cyclodextrin (G2-β-CD-Frax). Notably, G2-β-CD-Frax exhibited the highest solubilizing capacity, fast dissolution rate, and superior Caco-2 cell internalization with no obvious toxicity. Pharmacokinetic studies demonstrated markedly higher oral bioavailability of G2-β-CD-Frax (5.8-fold that of free drug) than other Frax-CDs. Further, long-term administration of G2-β-CD-Frax (5 mg/kg) efficiently inhibited CCl4-induced hepatic fibrosis in the mouse without inducing any toxicity. Our results will inspire the continued advancement of optimal oral Frax formulations for anti-fibrotic therapy.
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PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Zhenfu Wang,Yang Liu,Xiaoyan Dong,Yan Sun
Chemoenzymatic catalysis combining the traits of chemical and enzymatic catalysis provides tremendous possibilities for the design of biosynthetic pathways utilizing inorganic catalysts and enzymes. However, the efficiency of chemoenzymatic catalysis is usually governed by the synergy and compatibility of the two catalysts. Here, we report for the first time the catalase-like activity of cobalt phosphate nanocrystals (CoPs). By a one-pot biomimetic mineralization with CoPs and l-amino acid oxidase (LAAO) under a mild condition, we have fabricated a hybrid nanobiocatalyst, LAAO@CoPs, for the chemoenzymatic synthesis of α-keto acid. The as-fabricated nanobiocatalyst with directly contacted catalytic sites of the enzyme and nanozyme maximizes the substrate channeling effects for in situ chemical decomposition of the oxidative intermediate, H2O2, during the enzymatic oxidation of l-tryptophan (l-Trp), thus minimizing the H2O2 accumulation and byproduct generation. Benefiting from the superiority of LAAO@CoPs, complete conversion (100.0%) of l-Trp to indole pyruvic acid is achieved, over two times higher than the yield of the free LAAO system (47.6%). Meanwhile, LAAO@CoPs show high stabilities against heat and proteolytic treatments. This work offers a new design approach for constructing a high-performance nanobiocatalyst for cascade reactions, especially for those systems with toxic or reactive intermediates.
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高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Limin Wang,Yunsen Zhang,I. Agbaka Johnpaul,Kai Hong,Yumei Song,Xiao Yang,Chenyan Lv,Changwei Ma
Hops are abundant in natural bioactive compounds. In this work, nine prenylated bitter compounds from hop were evaluated for their inhibitory activity against α-glucosidase. As a result, four flavonoids and one phloroglucinol (lupulone, LP) outperformed acarbose in inhibiting α-glucosidase. Isoxanthohumol (IX) and LP with two types of structures were selected for inhibition mechanism studies by spectroscopic methods and molecular dynamics simulation (MD). Results showed that IX acted as noncompetitive inhibitor and bound to α-glucosidase in allosteric sites via hydrogen bonds, hydrophobic, van der Waals (vdW), and electrostatic force, whereas LP was uncompetitive inhibitor and bound to catalytic sites via hydrophobic and vdW interactions. Notably, the conformation around binding site of α-glucosidase formed stable α-helix and tightened after binding IX and LP, respectively, which helped to elucidate noncompetitive and uncompetitive inhibitory mechanisms. This work demonstrated that two types of prenylated bitter compounds are discrepant in their mechanisms of interaction with α-glucosidase.
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