International Journal of Minerals Metallurgy and Materials
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2024
·Vol. 30
·期 12
·2432-2440
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IF 5.6
Cao Duanhao,Ma Xiaofeng,Zhang Yipeng,Ta La,Yang Yakun,Xu Chao,Ye Feng,Liu Jianguo
Exploring and designing a high-performance non-noble metal catalyst for hydrogen evolution reaction (HER) are crucial for the large-scale application of H 2 by water electrolysis. Here, novel catalysts with NiMo nanoparticles decorated on reduced graphene oxide (NiMo@rGO) synthesized by a two-step hydrothermal method were reported. Physical characterization results showed that the prepared NiMo@rGO-1 had an irregular lamellar structure, and the NiMo nanoparticles were uniformly dispersed on the rGO. NiMo@rGO-1 exhibited outstanding HER performance in an alkaline environment and required only 93 and 180 mV overpotential for HER in 1.0 M KOH solution to obtain current densities of −10 and −50 mA·cm − 2 , respectively. Stability tests showed that NiMo@rGO-1 had a certain operating stability for 32 h. Under the same condition, the performance of NiMo@rGO-1 can be comparable with that of commercial Pt/C catalysts at high current density. The synergistic effect between NiMo particles and lamellate graphene can remarkably promote charge transfer in electrocatalytic reactions. As a result, NiMo@rGO-1 presented the advantages of high intrinsic activity, large specific surface area, and small electrical impedance. The lamellar graphene played a role in dispersion to prevent the aggregation of nanoparticles. The prepared NiMo@rGO-1 can be used in an-ion exchange membrane water electrolysis to produce hydrogen. This study provides a simple preparation method for efficient and low-cost water electrolysis to produce hydrogen in the future.
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JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 46
·21265-21276
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IF 3.5
Zhang Kewen,Fan Benwei,Wang Shidong,Zhang Hongwei,Liu Qunhong,Bao Xiaojun,Yuan Pei
Heterogeneous hydrogenation is an effective way to improve the performance of unsaturated polymers, but the preparation of supported catalysts with high metal dispersion and stability remains challenging. Herein, we synthesize a SiO 2 -based support wrapping with carbon nitride on the surface (CN x @SiO 2 ) via the thermal polycondensation of melamine, on which Pd nanoclusters with highly exposed active sites are formed and stably anchored via the strong interaction between N and Pd. The thermal temperature affects the properties of CN x , which further modulates the electronic and structural state of Pd nanoclusters. The Pd/CN x @SiO 2 -500 catalyst, prepared at 500 °C with an optimal CN x structure ( g -C 3 N 4 ) and high nitrogen content, features highly dispersed and electron-rich Pd nanoclusters (1.3 nm). This catalyst exhibits a hydrogenation activity of 98.0% for nitrile rubber, with a selectivity of 100% for C=C bonds. This work provides a facile method to prepare Pd catalysts with high activity and stability, paving the way for the upgrading of unsaturated polymers via hydrogenation. Graphical abstract
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Journal of Inorganic and Organometallic Polymers and Materials
·
2024
·
IF 3.9
Xie Lina,Li Yuhu,Liu Yushuai,Hu Wenjing,Fang Shiqiang,Chen Xue-Qiang
Adhesives are widely used to join fragments in the preservation and restoration of cultural heritage made of pottery. However, research into the inorganic adhesive for archaeological pottery bonding is scarce and is even non-existent for the comparison study between organic and inorganic adhesives. Nowadays, a novel environmental-friendly inorganic phosphate-based adhesive has been developed. To evaluate the adhesive scientifically and objectively, three epoxy resin adhesives have also been prepared and applied to the fractured specimens, tested and compared in laboratory to check their compatibility and durability in this experimental study. The compatibility characterization results indicate that the bonding strength of inorganic phosphate-based adhesives is closest to that of the pottery matrix. From the perspective of contact angle change, permeability and morphology, the epoxy resins showed a dense structure after curing, which obstructs the breathing channel of the pottery matrix, and therefore the water vapor permeability and water absorption are greatly reduced. Additionally, the cured adhesive specimens also undergo three types of artificially accelerated aging: dry-thermal, hygrothermal and UV irradiation. These adhesives’ long-term stability and durability have been monitored and compared in terms of weight change, chromatic variation, bonding strength measurements, microscopic observations and FTIR analysis. After a dry-thermal aging, the inorganic phosphate-based adhesive shows the highest strength retention rate (81%), the lowest weight change rate (-9.106 × 10 − 5 %) and the lowest color variation (ΔE* = 5.46). The findings suggest that the inorganic phosphate-based adhesive may offer advantages over commonly used epoxy resins in terms of physical-chemical compatibility with the pottery substrate and long-lasting resistance to aging. The purpose of this study is to reveal the benefits of using inorganic phosphate-based adhesive to bond shattered pottery through a comparative experiment, hoping to provide useful bonding materials and innovative research ideas for archaeological pottery conservation. Graphical Abstract
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
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2025
·
IF 3.1
Zhou Mengmeng,Jiang Zehua,Zhang Maosen,Feng Sa,Ma Boyuan,Kan Shunli,Fu Xuanhao,Zhu Rusen
This study aimed to investigate the potential pharmacological effects of icariin (ICA) in the treatment of spinal cord injury (SCI). Network pharmacology was used to focus on the potential targets and biological processes of ICA in SCI. Molecular docking was used to verify the ability of ICA to bind to its core targets. Finally, valuate the efficacy and potential mechanisms of ICA in treating spinal cord injury through in vitro and in vivo experiments. A total of 37 targets were screened out, and core genes were screened out from the protein‒protein interaction network. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that these targets are enriched mainly in response to hypoxia, regulation of the cellular response to stress, and the TGF-beta signaling pathway. Molecular docking analysis showed that ICA has good docking ability with core targets. In animal experiments, Basso, Beattie and Bresnahan scores, catwalk gait analysis, hematoxylin and eosin staining, and RT-qPCR showed that ICA can inhibit spinal cord inflammation and effectively improve the behavioral and histological recovery after SCI rats. Western blot and immunofluorescence showed that ICA can reduce astrocyte activation and downregulate the TGF-beta signaling pathway after SCI. In addition, ICA can promote axonal nerve elongation and promotes angiogenesis after spinal cord injury in rats. In vitro experiments revealed that ICA can inhibit TGFβ1-induced activation of the TGF-beta signaling pathway and astrocyte activation. ICA treats SCI through multiple targets and pathways. ICA plays a major role in protecting nerves, promoting angiogenesis, and inhibiting reactive astrocyte activation in the treatment of SCI.
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JOURNAL OF POLYMER RESEARCH
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2024
·Vol. 31
·期 7
·1-12
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IF 2.6
Shen Yunda,Ren Liang,Ma Hui,Liu Xiangpeng,Song Tao,Liu Qiang,Xue Mingxin,Li Chonghua,Shao Mingliang,Zhang Mingyao
This work aims to evaluate the influence of the incorporation of oyster shell powder (OSP) on the mechanical properties, thermal performance and crystallization behavior of green poly (butylene succinate) (PBS) composites by regulating the dispersed oyster shell power with the silane coupling agent. In the present study, fully biodegradable PBS composites have been successfully prepared by virtue of the melt blending with γ-Glycidoxypropyltrimethoxysilane (KH560) grafted oyster shell power namely OSP@KH560, enhancing the mechanical properties and thermal performance of the result materials. The incorporation of 20wt% OSP@KH560 into the composite promotes a dramatic increase of 48.1% in modulus of PBS composite. The result from thermogravimetric analysis (TGA) shows that thermal stabilities of PBS composites gradually increases with increasing the amount of OSP@KH560. By adding 30wt% OSP@KH560, the initial decomposition temperature of the PBS composite increases by 15℃. The DSC result demonstrates that the addition of OSP@KH560 at 30% leads to a crystallinity of 45.78% in the composites, which is 35.65% lower than that of PBS, indicating that OSP@KH560 promotes heterogeneous nucleation and accelerates the crystallization rate of PBS, thus reducing its crystallinity. This work provides a new option to prepare PBS composites with good performance and high-cost competitiveness, and further utilizes marine resources while breaking away from dependence on oil resources.
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Scientific Reports
·
2025
·Vol. 15
·期 1
·1-11
·
IF 3.9
Lu Pengpeng,Xu Jingyang,Liu Shuyan,Fu Lili,Wu Shengxian,Liu Ze,Hou Tu,Liu He,Huang Dongyan
The application of flexible hydrogel sensors in extreme environments, such as low temperatures, underwater, or significant mechanical deformations, poses considerable challenges. Here, we present a simple one-pot method to fabricate ultra-tough, swelling- and freezing-resistant conductive organohydrogels without external conductive and freeze-resistant fillers. During gelation, by-products (C 6 H 15 NHCl, KCl) provide both conductivity and antifreeze properties, thus eliminating compatibility issues and dispersion challenges associated with external fillers. The resulting gel exhibits super toughness, with tensile strength reaching 10.2 MPa and stretchability up to 800% in the dry state. Following covalent crosslinking, the gel demonstrates excellent anti-swelling properties, with a swelling ratio of only 15.4% after 24 h of water immersion, while maintaining a tensile strength of 5.8 MPa and an elongation of up to 1000%. When fabricated into flexible sensors, these gels display stable electrical responsiveness and desired Gauge Factor (0.58–2.25), effectively detecting limb movements. Furthermore, the gel’s superior resistance to freezing and swelling ensures reliable signal stability under both − 20 °C and underwater conditions. These combined properties render the conductive gel a promising candidate for flexible sensing components in robotic and bionic applications.
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Nano Research
·
2024
·
IF 9.5
Ma Xiaolu,Bian Qiong,Xu Yihua,Hu Jingyi,Hu Weitong,Wang Ruxuan,Zhang Yunting,Ye Yuxian,Sheng Xiaoxia,Zhang Tianyuan,Gao Jianqing
Psoriasis is a chronic skin disease characterized by the hyperproliferation of keratinocytes and an overactive autoimmune response. Photodynamic therapy (PDT) has been established as a promising intervention for alleviating psoriasis. However, the current transdermal delivery of photosensitizers is inefficient and imprecise. In this study, we developed a foamed microemulsion nanodroplets system containing chlorin e6 (Ce6 FM), exhibiting precise epidermal targeting and retention, which targeted the aberrantly proliferating epidermal cells at psoriatic skin lesions and avoided the damage to the normal cutaneous cells. Upon application in a psoriatic mouse model, Ce6 FM efficiently induced keratinocyte apoptosis by generating reactive oxygen species under laser. Furthermore, Ce6 FM-based PDT activated the cyclooxygenase-2-induced immunosuppressive pathway in keratinocytes, resulting in the amelioration of the autoimmune microenvironment in psoriatic skin. Additionally, Ce6 FM-based PDT did not induce skin damage or atrophy associated with non-targeted halometasone treatment. Overall, Ce6 FM-based PDT holds promise as an effective, safe and compliant strategy for psoriasis treatment.
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CELLULOSE
·
2024
·
IF 4.9
Xiong Jing,Wu Liang,Xiao Gang,Ma Yan,Ran Ruilong,Sun Wei,Wang Wei,Mao Cuiping,Qiao Yan,Lu Zhisong
A microfluidic thread/paper-based analytical device (µTPAD) is of great significance in biomedical analysis and point-of-care diagnostics. Nevertheless, the research has not been done on the ion distribution on the thread and how it affects sensing so far. Inspired by the sweat stains on the clothes, a high-performance µTPAD based on the evaporation-induced ion enrichment is presented for glucose monitoring in salty solutions. In comparison to the multi-ply cotton thread, the single-ply cotton thread exhibits the most significant ion-enrichment capability at the rear segment, which could be attributed to the balance between the water evaporation and the solution replenishment in the thread. The salts accumulated at the rear segment could increase the ionic strength of the solution passed through the thread, promoting the colorimetric reaction on the paper-based sensing unit. The single-ply thread with strong ion-enrichment capability was integrated with a paper-based glucose sensor to prepare a µTPAD for highly sensitive glucose detection in both PBS and artificial sweat (-0.673µM −1 in PBS and − 0.253 µM −1 in artificial sweat). Moreover, the system could detect glucose in human sweat samples with high accuracy and precision. This work may provide a strategy to prepare a highly sensitive µTPAD for precise analysis of substances in bio-fluids, particularly human sweat. Graphical Abstract
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Wang Jingnan,Zhao Kaiheng,Yao Yongbin,Xue Fan,Lu Fei,Yan Wensheng,Yuan Fangli,Wang Xi
Magnetic field effects (MFE) of ferromagnetic spin electrocatalysts have attracted significant attention due to their potential to enhance catalytic activity under an external magnetic field. However, no ferromagnetic spin catalysts have demonstrated MFE in the electrocatalytic reduction of nitrate for ammonia (NO 3 RR), a pioneering approach towards NH 3 production involving the conversion from diamagnetic NO 3 − to paramagnetic NO. Here, we report the ferromagnetic Fe-TiO 2 to investigate MFE on NO 3 RR. Fe-TiO 2 possesses a high density of atomically dispersed Fe sites and exhibits an intermediate-spin state, resulting in magnetic ordering through ferromagnetism. Assisted by a magnetic field, Fe-TiO 2 achieves a Faradaic efficiency (FE) of up to 97% and an NH 3 yield of 24.69 mg mg cat − 1 at −0.5 V versus reversible hydrogen electrode. Compared to conditions without an external magnetic field, the FE and NH 3 yield for Fe-TiO 2 under an external magnetic field is increased by ~21.8% and ~ 3.1 times, respectively. In-situ characterization and theoretical calculations show that spin polarization enhances the critical step of NO hydrogenation to NOH by optimizing electron transfer pathways between Fe and NO, significantly boosting NO 3 RR activity.
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BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
·
2024
·
IF 1.5
Li Yufang,Chen Yunlong,Zi Futing,Hu Xianzhi
Eco-friendly gold extraction from printed circuit boards (PCBs) is highly attractive due to the increasing demand for gold in various fields. The conventional Cu 2+ -NH 3 - S 2 O 3 2− method for PCBs involves polluting NH3 gas and requires additional copper. This study explored a new eco-friendly alternative using ethylenediamine (en) and thiosulfate to extract gold from CPU (the PCB material used in this study). The results showed that 81% of gold in CPUs could be successfully leached out after 48 h, using 10 mM ethylenediamine and 0.2 M thiosulfate. Various analyses, including SEM, ICP, XPS, were conducted to further investigate the process. It was found that the metal in CPU was Au(0) → Ni(II) → Cu(0) from the outside to the inside, and possible gold leaching mechanism was related to the oxidation of Cu(en) 2 2+ produced from CPU’s defective position and the presence of S 2 O 3 2− . As for Au(S 2 O 3 ) 2 3− recovery, different from our previous study, it is necessary to add a small amount of ethylenediamine (en) except for carbon and thiosemicarbazone (TSC); consequently, a gold adsorption efficiency of 99% was achieved. In summary, the leaching method proposed in this work solved the problem of NH 3 pollution of traditional one and achieves green, efficient, and selective gold adsorption from CPU leaching solution through a simple method, which is hopeful to replace the traditional unfriendly Cu-NH 3 - S 2 O 3 2− .
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JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
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2024
·
IF 2.6
Li Ya,Liang Jianfeng,Liang Lili
Pile fermentation plays a crucial role in the formation of the unique flavor of Liupao tea, which can effectively reduce the bitterness of the tea and promote the formation of red tea soup. In this study, the non-volatiles changes of Liupao tea during pile fermentation processing were fully analyzed by UPLC-QTOF-MS/MS. A total of 271 metabolites with significant differences were identified in Liupao tea during pile fermentation( P < 0.01, VIP > 1), and their trends were grouped into 10 subclasses by K-means analysis. Three differential metabolites Choline Alfoscerate, N1-Methyl-4-pyridone-5-carboxamide, and 2-Aminovalienone were shared among the three different pile fermentation periods. The results provided valuable information for understanding the dynamic changes of non-volatile substances during the pile fermentation process of Liupao tea.
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ACTA PHARMACOLOGICA SINICA
·
2024
·
IF 6.9
Yang Ya-qi,Liu Yi-jun,Qiao Wen-xuan,Jin Wei,Zhu Shun-wei,Yan Yu-xi,Luo Qiong,Xu Qiang
Primary Sjögren’s syndrome (pSS) is a chronic inflammatory autoimmune disease with an unclear pathogenesis, and there is currently no approved drug for the treatment of this disease. Iguratimod, as a novel clinical anti-rheumatic drug in China and Japan, has shown remarkable efficacy in improving the symptoms of patients with pSS in clinical studies. In this study we investigated the mechanisms underlying the therapeutic effect of iguratimod in the treatment of pSS. Experimental Sjögren’s syndrome (ESS) model was established in female mice by immunizing with salivary gland protein. After immunization, ESS mice were orally treated with iguratimod (10, 30, 100 mg·kg −1 ·d −1 ) or hydroxychloroquine (50 mg·kg −1 ·d −1 ) for 70 days. We showed that iguratimod administration dose-dependently increased saliva secretion, and ameliorated ESS development by predominantly inhibiting B cells activation and plasma cell differentiation. Iguratimod (30 and 100 mg·kg −1 ·d −1 ) was more effective than hydroxychloroquine (50 mg·kg −1 ·d −1 ). When the potential target of iguratimod was searched, we found that iguratimod bound to TEC kinase and promoted its degradation through the autophagy-lysosome pathway in BAFF-activated B cells, thereby directly inhibiting TEC-regulated B cells function, suggesting that the action mode of iguratimod on TEC was different from that of conventional kinase inhibitors. In addition, we found a crucial role of TEC overexpression in plasma cells of patients with pSS. Together, we demonstrate that iguratimod effectively ameliorates ESS via its unique suppression of TEC function, which will be helpful for its clinical application. Targeting TEC kinase, a new regulatory factor for B cells, may be a promising therapeutic option.
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