MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 10
·1-10
·
IF 5.3
Yang Haixia,Xue Yijiong,Wang Tingting,Lu Yan,Yang Minghui,Li Xiaoqing,Li Ting
Ratio-based fluorescence assays can reduce environmental interference, allowing for the identification of biomarkers with higher specificity. However, the complicated preparation procedures involved in developing multi-fluorescent emission probes and the challenges associated with isolating and enriching specific biomarkers from complex samples present formidable obstacles. Magnetic nanoparticles enable the quick separation and enrichment of biomarkers, hence, the present study developed a ratio-fluorescence assay for the detection of interleukin-8 (IL-8) using carbon dots (CDs) with both magnetic and fluorescent properties. In this approach, magnetic and fluorescent Fe 3 O 4 -CDs-1 (FCs) hybrid nanoparticles were initially synthesized, followed by the growth of SiO 2 nanorods on their surface. FCs@SiO 2 -Ab 1 was then prepared by immobilizing capture IL-8 antibody (Ab 1 ) through amino modification onto FCs@SiO 2 to selectively capture and enrich target IL-8 from samples. Subsequently, CDs-2 modified with detection IL-8 antibody (Ab 2 ) served as IL-8 detection probe, which formed sandwich structure with FCs@SiO 2 -Ab 1 in the presence of IL-8. As the concentration of IL-8 increased, the fluorescence intensity of CDs-2 enhanced accordingly while the fluorescence intensity of FCs remained relatively unchanged. This ratio-fluorescence sensing platform exhibits a wide linear range (20-1000 pg·mL −1 ) and an impressive low detection limit (6.9 pg·mL −1 ). Furthermore, this method enables the reliable detection of IL-8 in human serum, thereby offering promising prospects for the development of enrichment and detection systems for other biomarkers. Graphical
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高影响因子
NANOTECHNOLOGY
·
2024
·Vol. 35
·期 42
·425603
·
IF 2.9
Hao Chen,ZhaoGuo Wu,AiWu Zhao,Jin Wang
To enhance the stability of Raman reporters, these reporters were trapped in a metal organic framework (MOF) exoskeleton that was grown and compressed on Fe3O4@Au core–satellites, producing recyclable surface-enhanced Raman scattering (SERS) nanotags. Furthermore, encapsulation of Raman reporters in the assembled MOF-based nanocomposites was divided into two types of patterns, pre-enrichment and post-enrichment, in order to disentangle chemical enhancement of charge transfer (CT) from electromagnetic enhancement (EM) in SERS. Hence, to demonstrate the effect of encapsulation, a typical non-thiolated Raman reporter, for example crystal violet (CV) trapped in a core–satellite nanoassembly-based zeolitic imidazolate framework (ZIF-8) shell, was selected. The results suggest that stability and Raman intensity are remarkably improved. Moreover, the pattern of incorporation of CV into the ZIF-8 shell with tunable shell thickness can contribute to the disentangling of CT effects from EM effects.
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Membranes
·
2025
·Vol. 15
·期 9
·277
·
IF 3.6
Lei Ni,Qiancheng Cui,Zhe Wang,Xueting Zhang,Jun Ma,Wenjuan Zhang,Caihong Liu
The inherent hydrophobicity of poly(vinylidene fluoride) (PVDF) ultrafiltration membranes leads to severe membrane fouling when processing proteinaceous solutions and organic contaminants, significantly limiting their practical applications. This study presents a novel metal-ion mediated co-deposition strategy for fabricating high-performance antifouling poly(vinylidene fluoride) (PVDF) hollow fiber ultrafiltration membranes. Through Zn2+coordination-driven self-assembly, a uniform and stable composite coating of dopamine (DA), tannic acid (TA), and ZIF-8 nanoparticles was successfully constructed on the membrane surface under mild conditions. The modified membrane exhibited significantly enhanced hydrophilicity, with a water contact angle of 21° and zeta potential of −29.68 mV, facilitating the formation of a dense hydration layer that effectively prevented protein adhesion. The membrane demonstrated exceptional separation performance, achieving a pure water permeability of 771 L/(m2∙h∙bar) and bovine serum albumin (BSA) rejection of 97.7%. Furthermore, it showed outstanding antifouling capability with flux recovery rates exceeding 83.6%, 74.7%, and 71.5% after fouling by BSA, lysozyme, and ovalbumin, respectively. xDLVO analysis revealed substantially increased interfacial free energy and stronger repulsive interactions between the modified surface and protein foulants. The antifouling mechanism was attributed to the synergistic effects of hydration layer formation, optimized pore structure, additional water transport pathways from ZIF-8 incorporation, and electrostatic repulsion from negatively charged surface groups. This work provides valuable insights into the rational design of high-performance antifouling membranes for sustainable water treatment and protein separation applications.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Junge Xu,Weihao Yu,Ziwei Zhang,Fubin Deng,Shengkong Wang,Rusen Zou,Yingmu Wang,Baoling Yuan
Pollution from extensive sulfonamide antibiotic use is a critical research focus, particularly in the remediation of these antibiotics using composite materials. This study employed a CuFe 2 O 4 /ZIF-8 composite to activate sodium percarbonate (SPC) for the photo-Fenton-like degradation of the sulfonamide antibiotic sulfamethoxazole (SMX). The optimal conditions for SMX degradation were determined using the CuFe 2 O 4 /ZIF-8/SPC/Vis system: a ZIF-8 composite ratio of 40 %, catalyst dosage of 0.15 g/L, SPC concentration of 0.8 mM, and initial pH of 3.0, achieving complete SMX removal within 30 min. After five cycle tests, the leaching rates of copper and iron ions were 0.179 mg/L and 0.376 mg/L, respectively, significantly lower compared to the use of CuFe 2 O 4 alone as the catalyst (Cu: 0.46 mg/L, Fe: 1.43 mg/L). The radicals present in the system were identified, with their contribution rates ranked from highest to lowest as follows: ·OH > h + > ·O 2 – > CO 3 · - > 1 O 2 . Further mechanistic investigations revealed that the heterogeneous structures in CuFe 2 O 4 /ZIF-8 enhanced the efficiency of the photo-Fenton-like reaction by facilitating electron transfer. This study introduced an innovative approach for antibiotic treatment using the CuFe 2 O 4 /ZIF-8 composite under visible light irradiation and broadened the technical framework of SPC-based advanced oxidation processes (AOPs) for treating wastewater.
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Metabolites
·
2025
·Vol. 15
·期 9
·625
·
IF 3.7
Hai Zhao,Kangwei Shen,Wei Fan,Mengjie Li,Xuejun Kang
Purpose: To explore the potential relationship between salivary amino acid concentrations and 8 km running performance in male undergraduate students. Methods: Thirty male undergraduate students were recruited. Participants completed an 8 km run while wearing smart bracelets. Saliva samples were collected before, immediately after, and 24 h after the run. Ultra-High Performance Liquid Chromatography (UHPLC) was used to quantify salivary amino acids. Results: The fast group (average speed > 12.80 km/h) had a significantly shorter running time (35.66 ± 1.30 min,p< 0.001) and higher speed (13.59 ± 0.46 km/h,p< 0.001) than the slow group. Before the run, salivary serine concentration (20.19 µg/mL,p= 0.013) was higher in the fast group. After 24 h, salivary glutamine concentration (6.65 µg/mL,p= 0.047) was lower in the fast group. Salivary threonine concentration was positively correlated with running speed. For every 1 µg/mL increase in salivary threonine concentration, average running speed increased by 0.011 km/h, and this correlation persisted after adjusting for age and heart rate. Conclusions: This study found a positive correlation between salivary threonine and 8 km running speed, along with differences in serine and glutamine concentrations among runners with different speeds. These findings provide preliminary evidence for the relationship between salivary amino acid concentrations and running performance, though further research with larger samples and diverse exercise types is needed.
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APPLIED CATALYSIS A-GENERAL
·
2022
·
IF 5.723
Kunpeng Song,Wen Dong,Cheng Tang,Zhijuan Zou,Yundang Wu
In this study, a novel and highly efficient ORR catalyst is designed via the pyrolysis of zeolitic imidazole framework-8 (ZIF-8) under the protection of hypercrosslinked iron porphyrins . Fe 3 O 4 nanoparticles with oxygen vacancies are formed in situ and promoting catalytic efficiency. Benefiting from the synergistic effect among the Fe 3 O 4 and ZIF-8 skeleton, the hybrid catalyst exhibits excellent ORR activity even surpassing commercial Pt/C. The pyrolyzation temperature is studied in detail and determined to be a crucial parameter for ORR performance. Nano-Fe 3 O 4 , which has high catalytic efficiency, is formed in situ at 800 ℃. Amorphous iron is formed at 600 ℃ and 700 ℃, and zero-valent iron is formed at 900 ℃. The content of oxygen vacancies, Fe–N, and graphite–N, which are beneficial to the ORR reaction, are all reached to a maximum at 800 ℃. This study provides a new approach to design highly active Fe 3 O 4 -based electrocatalytic materials.
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高影响因子
PROGRESS IN ORGANIC COATINGS
·
2023
·
IF 6.6
Weibin Bai,Xu Zhang,Zhencheng He,Yao Qian,Rongkun Jian,Yucai Lin,Yanlian Xu
The incalculable metal corrosion loss makes the research of long-term corrosion resistant coatings attract much attention. Herein, we demonstrated a new strategy for constructing a pH-responsive nanocontainer as a gatekeeper, which consisted of a laminated double hydroxide (LDH) surface in situ grown ZIF-8 containing the corrosion inhibitor of 2-mercaptobenzimidazole (MBM). The shell-core structures of the composite fillers displayed the excellent barrier performance and pH-responsive controlled release properties in epoxy (EP) coatings. Electrochemical impedance spectroscopy and salt spray tests were conducted to investigate the multifunctional role in providing an intelligent anti-corrosion MBM@ZIF-8@LDH/EP composite coating . After immersing in salt solution (3.5 wt%) for 30 days, the impedance value of the MBM@ZIF-8@LDH/EP coating at 0.01 Hz (|Z| 0.01 Hz ) was 2.82 × 10 8 Ω∙cm 2 , which was about four orders of magnitude higher than that of the epoxy coating (1.54 × 10 4 Ω∙cm 2 ). The outstanding corrosion protection of MBM@ZIF-8@LDH was attributed to not only the compactness improvement of the composite coating, but also the anion exchange capability to act as a storage station for chloride ions. Meanwhile, the active filler could be used as a pH-responsive nanocontainer to release the loaded corrosion inhibitor of MBM and prevented further damage to the steel substrate, displaying a self-healing behavior. This strategy provides a new idea to combine perfect barrier effect and active anti-corrosion performance to prepare high-performance anti-corrosion and self-healing coatings. The multi-protective smart anti-corrosive coating would be a candidate with excellent performance for use in a variety of fields.
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JOURNAL OF CHROMATOGRAPHY A
·
2015
·
IF 4.169
Xiaomei Liu,Zhiwei Sun,Guang Chen,Wanwan Zhang,Yiping Cai,Rongmei Kong,Xiaoyan Wang,Yourui Suo,Jinmao You
In this study, the magnetic Zeolitic Imidazolate Framework-8 (ZIF-8) microspheres were successfully synthesized and applied as an effective sorbent for preconcentration of several typical phthalate esters (PAEs) from environmental water samples. Firstly, the solvothermal treatment method was used for preparation of Fe 3 O 4 nanoparticles. Then, mercaptoacetic acid (MAA) was served as the functionalized chemical to modify Fe 3 O 4 nanoparticles. The Fe 3 O 4 @ZIF-8 core–shell microspheres were synthesized through coating the MAA-capped Fe 3 O 4 nanoparticles with ZIF-8. By coupling magnetic solid-phase extraction (MSPE) with high-performance liquid chromatography (HPLC), a reliable, sensitive and cost-effective method for simultaneous determination of five main PAEs including dimethyl phthalate (DMP), diethyl phthalate (DEP), di- n -butyl phthalate (DBP), benzyl butyl phthalate (BBP), and dioctyl phthalate (DOP) was developed. Good linearity was observed in the range of 1.0–100.0 μg/L. The limits of detection (S/N = 3) and limits of quantification (S/N = 10) were in the range of 0.08–0.24 and 0.3–0.8 μg/L, respectively. The relative standard deviations were less than 5.5% and the accuracies of the method for the PAEs were in the range from 85.6% to 103.6%. Finally, the Fe 3 O 4 @ZIF-8 was successfully applied for rapid extraction of trace amounts of PAEs in environmental water samples.
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Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 42
·21029-21038
·
IF 9.931
Liang Zhang,Jing Wang,Xinyi Ren,Wentao Zhang,Tianshu Zhang,Xinnan Liu,Ting Du,Tao Li,Jianlong Wang
The excessive accumulation of toxic copper species makes it imperative to develop smart dual-functional materials for the simultaneous removal and detection of Cu(II) in drinking water. In this work, novel core–shell NH2-MIL-101(Al)@ZIF-8 nanoflowers were successfully fabricated via an internal extended growth mode under the regulation of polyvinylpyrrolidone (PVP) to achieve this goal. Benefiting from the specific affinity of imidazole nitrogen in ZIF-8 toward Cu(II), the resultant NH2-MIL-101(Al)@ZIF-8 shows high adsorption capacity (526.74 mg g−1). Moreover, the fluorescence of NH2-MIL-101(Al) shows a Cu(II)-dependent change, causing this composite to possess superior selective/sensitive detection with a broad linear range (1.5–625 μM) and a low detection limit (0.17 μM) for Cu(II). Specifically, the hybrid MOF@MOF structure provides greater sensitivity as compared to the individual constituent (pristine NH2-MIL-101(Al)) and the mixed state, which is ascribed to the rational optimization of the smart adsorbent based on the following two aspects. (i) The synergistic effect of the core–shell nanostructure improves the preconcentration ability at the interface between single MOFs. (ii) The existence of the three-dimensional hierarchical nanoflower architecture (structure optimization) accelerates the mass transport and sculpts the final composite with enhanced adsorption and detection ability. These indicate that the smart NH2-MIL-101(Al)@ZIF-8 nanoflower could be an excellent candidate for the synchronous remediation and selective detection of Cu(II) in aqueous systems, which could be potentially useful in wastewater treatment and water quality monitoring.
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CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Ming Li,Xiaofei Fan,Jianfeng Li,Jianwei Mao,Yuchen Zhang,Rujie Wang,Huining Xiao
In this study, a novel alginate-based composite hydrogel sphere embedded with zeolite imidazole framework (ZIF-8) and carbon dots (CDs) was developed for simultaneous efficient adsorption and selective detection of mercury ions (Hg 2+ ). The hydrogel spheres (Z8S-CDs) integrate the porous structure of ZIF-8 for efficient Hg 2+ adsorption and the fluorescence properties of CDs for visual detection. The adsorption capacity of Z8S-CDs reached 381.67 mg/g for Hg 2+ , significantly surpassing conventional alginate hydrogels, attributed to synergistic chemisorption and pore-filling mechanisms. Meanwhile, the hydrogel spheres exhibited selective fluorescence quenching upon Hg 2+ binding, enabling rapid detection with a low detection limit (3.63 × 10 −8 M) and high specificity against competing ions. The hydrogel spheres maintained structural stability and reusability over multiple cycles. This work provides a dual-functional platform for effective Hg 2+ removal and real-time monitoring in contaminated water, highlighting its potential for environmental remediation applications.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qing Fu,Manxia Wang,Jia Shu,Guangjun Xiao,Zhujun Ai,Xin Gao,Huan Cai,Yan Zhao,Xuhuai Fu,Zhizhong Li,Mengjie Zhang,Jinzhou Feng,Juan Li,Rui Chen
Neuromyelitis optica spectrum disorder (NMOSD) is a neurological disease with rapid progression that can lead to severe visual impairment and paralysis. Rapid diagnosis at presentation significantly improves its prognosis, but there is a lack of available point-of-care testing (POCT) methods. Herein, for the first time, a colorimetric-fluorescent bifunctional nanoparticles (CFNPs)-based bimode lateral-flow immunoassay (LFIA) was developed for rapid and sensitive on-site diagnosis of NMOSD biomarker (AQP4-IgG). We first developed a novel sonochemistry-assisted strategy for the ordered self-assembly of CdTe quantum dots (QDs) using metal-organic framework (MOF) and polydopamine (PDA) flexible scaffold modification to fabricate CdTe@ZIF-8@PDA. Through rational design, the synthesis efficiency and fluorescence intensity of CdTe@ZIF-8 were 15-times and 9.67-times higher than those of the traditional synthesis method, respectively, and the colorimetric signal brightness and stability were significantly improved. The limit of detection of the CdTe@ZIF-8@PDA-labelled LFIA for AQP4-IgG titer detection by naked-eye colorimetric and smartphone-based fluorescence signal were 1:1.56 and 1:0.78, which were comparable to those of the gold standard cell-based assay (CBA). The diagnostic specificity and sensitivity for 121 clinical samples were 100 % and 82.35 % (colorimetric), and 100 % and 80.39 % (fluorescent). Our work has demonstrated an innovative strategy for constructing CFNPs and NMOSD on-site diagnostic approach that can be used for POCT.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Wenxuan Zu,Xinye Shao,Mojie Sun,Yu Sun,Ziang Liu,Xinghui He,Tianhong Zhou,Shijie Wang,Xiaojun Zhang
The frequent spills of offshore oil pose a great threat to the ecological environment and human health. Therefore, developing an adsorption material that is efficient, environmentally friendly, and easy to operate in complex environments to replace traditional technologies with low efficiency has become a major challenge in the field of oil-water separation. In this work, a green and superhydrophobic melamine sponge was first developed, inspired by lotus leaves. Then, a core-shell structure of inorganic metal oxide @ metal-organic framework (SiO 2 @ZIF-8) was synthesized by a simple sol-gel method. Finally, the structure was anchored onto the melamine sponge using low-surface-energy polydimethylsiloxane (PDMS), forming a unique hierarchical micro-nano structure. The modified sponge exhibited excellent superhydrophobicity (water contact angle = 156°) and oil adsorption capacity (ranging from 58.5 to 114.3 g/g). It still exhibited perfect mechanical properties, hydrophobicity stability, and thermal stability even under prolonged high temperatures, strong acids/bases, and multiple cycles of extreme compression. Furthermore, the material also demonstrated remarkable flame retardancy, which significantly enhances the safety of the sponge in practical applications. This study provides an efficient and sustainable practical solution for responding to oil spills, with broad application prospects.
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