APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Haijun Wang,Jin-Le Lan,Haocheng Yuan,Shicheng Luo,Yiqian Huang,Yunhua Yu,Qing Cai,Xiaoping Yang
Microstructure design combined with high-level heteroatoms doping has been considered the leading approach for preparing the high-performance carbon anodes for sodium-ion batteries (SIBs). Herein, a hollow porous carbon sphere (NP-HPCS) that exhibits a high N, P co-doping level (6.05 at% for N, 5.19 at% for P) and a large microporous specific area (339 m 2 g −1 ) is reported. The microporous and N, P co-doping synergistic construction of the NP-HPCS was achieved by a high-efficiency chemical grafting of hexachlorocyclotriphosphazene (HCCP) onto polydopamine (PDA) shell, accompanied by the in situ micellar transformation of pore-forming agent F127 in the grafting process. The as-prepared NP-HPCS used as an anode for SIBs delivers a superior rate capacity (~101 mAh g −1 at 20 A g −1 ) and an excellent long cycle performance (~120 mAh g −1 after 5000 cycles at 5 A g −1 ). The kinetics analysis and density functional theory (DFT) calculations were carried out to further analyze the superior sodium storage performance of NP-HPCS. Our work suggests an effective way to develop high-performance carbon anode materials for SIBs.
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高影响因子
Nano Energy
·
2019
·
IF 15.548
Yang Gao,Zhichang Xiao,Debin Kong,Rashid Iqbal,Quan-Hong Yang,Linjie Zhi
Carbon-based metal-free electrocatalysts have inspired extensive efforts to explore their applications in many nontrivial electrochemical reactions , such as oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER), by virtue of the integrated advantages including low cost, sustainability , longevity, and multifunctionality . Herein, N,P co-doped hollow carbon nanofiber ( N ,P–HCNF) membranes were facilely prepared via coaxial electrospinning technology, which are bestowed with a hierarchical porous architecture, turbostratic structures, and abundant catalytically active sites such as doping, defects, and edges. Benefiting from structural features of the one-dimensional (1D) carbon hollow nanoarchitecture, which affords plentiful active sites, continuous conducting pathways, and benign mass transfer channels, the resultant catalyst reveals an excellent trifunctional electrocatalytic activity for ORR, OER, and HER. Impressively, it exhibits one of the best metal-free bifunctional electrocatalytic activities in oxygen electrocatalysis as characterized by a low potential deviation (Δ E ) of 0.73 V between the half-wave potential ( E 1/2 ) for ORR and the potential reaching 10 mA cm −2 ( E j=10 ) for OER. Significantly, further investigations demonstrate that the effect of mass transfer makes a great difference to electrocatalytic activity , mainly through enlarged specific surface area to affect intrinsic catalytic activity and the ionic resistance in pores. This work sheds light on the design, fabrication, and regulation of highly active metal-free electrocatalysts with abundant active sites and tuned pore structures for electrocatalysis and other applications.
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高影响因子
MATERIALS & DESIGN
·
2024
·
IF 7.6
Biao Li,Weicheng Zhou,Xinmin Wang,Wanyi Zhong,Qin Zheng,Yingchong Chen,Pengfei Yue
Mucus clearance, epithelium mucosal barrier and P-glycoprotein (P-gp) efflux are the main gastrointestinal barriers that limit the oral delivery of nanoparticles. Inspired by tunable particles surface properties-dependent trans -mucus and trans -mucosal abilities, novel bilayer-functionalized mesoporous silica nanoparticles (MSN) containing D- α -tocopheryl polyethylene glycol succinate (TPGS) and sulfobetaine 12 (SB12) were designed by layer-to-layer assembly. The amino-grafted MSN (MSN-NH 2 ) was firstly functionalized with TPGS as hydrophobic layer (MSN-TPGS), and then SB12 was self-assembled on the hydrophobic surface of MSN-TPGS to generate a neutral and hydrophilic MSN (MSN-TPGS@SB12). Compared with MSN-NH 2 , MSN-TPGS, and MSN-TPGS@P123, the MSN-TPGS@SB12 possessed “one stone three birds” functions that enhanced mucus penetration, increased trans -mucosal absorption, as well as suppressed P-gp efflux. The pharmacokinetics study demonstrated that the MSN-TPGS@SB12 loading puerarin (MSN-TPGS@SB12-PUE) exhibited much higher bioavailability compared to other PUE-loaded formulations. Furthermore, the MSN-TPGS@SB12-PUE could significantly enhance the anti-inflammatory efficacy of PUE in vitro and in vivo . In summary, bilayer-functionalized MSN-TPGS@SB12 is a promising vehicle for overcoming the multiple gastrointestinal barriers (mucus clearance, intestinal epithelium barrier and P-gp efflux). Meanwhile, this study also provides a better understanding of the importance of tunable surface property of MSN on oral delivery of drugs.
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Hongye Li,Jingyu Tan,Song Yang,Yapeng Sun,Huangzhong Yu
Two-dimensional (2D) materials have attracted attention due to their excellent optoelectronic properties, but their applications are limited by their defects and vacancies. Surface modification is an effective method to restore their performance. Here, ZrSe2 is modified with conductive polymer p-toluenesulfonic acid (PTSA). It is found that PTSA can obtain electrons of ZrSe2 through the combination of −SO3H and ZrSe2, thus forming interfacial dipoles, which improve the work function of ZrSe2. In addition, −OH in PTSA can effectively fill the Se vacancy in ZrSe2 to form P-type doping, thereby improving its conductivity. ZrSe2 modified by the PTSA material is first used as a hole transport layer (HTL) in organic solar cells (OSCs). The efficiency of OSCs based on the PBDB-T:ITIC and PM6:L8-BO binary active layer with ZrSe2:PTSA as the novel HTL reaches 10.66 and 18.14%, which are obviously higher than the efficiency of OSCs with pure ZrSe2 as the HTL (8.48 and 15.64%). More interestingly, the stability of the device with ZrSe2:PTSA as HTL is significantly better than that of PEDOT:PSS. This study shows that the modification of the organic material can effectively improve the photoelectric performance of ZrSe2 and explores the physical mechanism of the interaction between the organic modifier and 2D materials.
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PubMed
高影响因子
BIOCHEMICAL PHARMACOLOGY
·
2020
·
IF 4.96
Hongwei Yao,Jingkai Gu,Yuqin Shan,Yani Wang,Xue Chen,Dong Sun,Yingjie Guo
Patients with diabetic mellitus tend to have a poor response to clopidogrel (Clop) due to reduced generation of active metabolite (Clop-AM). However, the underlying mechanism is not elucidated. A type 2 diabetic mellitus (T2DM) rat model was established by combining high-fat diet feeding and low-dose streptozotocin (STZ) injection. The reduced Clop-AM exposure was observed in T2DM rats after oral administration of Clop. However, in vitro liver microsomes incubated with Clop exhibited increased Clop-AM levels in T2DM rats due to a significant decrease in carboxylesterase (CES)1 expression and activity and a significant increase in the expression or activity of CYP1A2 and CYP3A . Interestingly, different from oral administration, the significantly increased C max of Clop-AM was observed in T2DM rats after intravenous injection, with no difference in AUC 0-t and t 1/2 values between the two strains. Meanwhile, in situ single -pass intestinal perfusion study showed lower absorption rate constant ( K a) and effective apparent permeability values ( P eff ) of Clop in T2DM rats than in control rats. It is explained by the increased expression or function of P-glycoprotein (P-gp) and pregnane X receptor (PXR) in duodenum and jejunum of T2DM rats. Moreover, the decreased Clop-AM level in T2DM rats was eliminated by the pretreatment of cyclosporin A , a P-gp inhibitor. It suggests that intestinal absorption, not hepatic metabolism is responsible for the reduced Clop-AM exposure in T2DM rats. P-gp might be the key factor causing the reduction of Clop absorption, consequently making less Clop available for Clop-AM formation.
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Fan Zhang,Jianru Huang,Rui Ou,Jiannan Chen,Weirong Yao,He Qian,Yuliang Cheng
In this study, novel dual-emission Au nanoclusters (BSA@CDs-BSA-AuNCs) were developed via a two-step in-situ synthesis strategy. Step one, bovine serum albumin (BSA) doped carbon dots (BSA@CDs) covalently bound to BSA under the coupling effect of N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) to obtain BSA@CDs-functionalized BSA (BSA@CDs-BSA); step two, in-situ synthesis of Au nanoclusters using BSA@CDs-BSA as template was conducted and BSA@CDs-BSA-AuNCs with a size of 30 nm and two characteristic emission peaks at 450 and 675 nm confirmed to be attributed to BSA@CDs and BSA-templated AuNCs (BSA-AuNCs) respectively were fabricated, presenting an emission separation of 225 nm. The prepared nanoclusters were fully characterized. Notably, the two characteristic emission peaks both have been redshifted compared to the original BSA@CDs and BSA-AuNCs respectively, due to possible charge transfer occurred between BSA ligand and the above two fluorophores. Further, it has been applied to establish an original ratiometric fluorescence sensor for p-nitrophenol (p-NP) detection with excellent performance, which has not been reported in literatures.
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产品关联
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高影响因子
ACS Applied Energy Materials
·
2021
·
IF 6.024
Zheng Jiang,Jun Wang,Enyi Hu,Jingjing Liu,Lei Yu,Faze Wang
The p-i-n junction structure has garnered great interest from researchers due to its increased photoactive area and wider space charger region compared with that of the p-n junction. Herein the ultrawide bandgap (∼6.7 eV) semiconductor alumina (Al2O3) has been introduced to construct a p-i-n junction with ZnO and NiO. ZnO–Al2O3–NiO powders are suitable for electrolyte membrane material of low-temperature solid oxide fuel cells (LT-SOFCs). The insulating Al2O3 brings a doubled depletion region and more effective charge separation compared with the p-n junction consisting of ZnO and NiO. The fuel cell based on the p-i-n junction membrane material delivers an enhanced maximum power density (MPD) of 917 mW cm–2 along with a high open-circuit voltage (OCV) of 1.013 V at 550 °C. An analysis based on the space charge region and energy band alignment in the p-i-n junction is proposed to account for the appreciable cell performance and ionic conductivity, as well as the electron blocking and charge separation ability. This study presents a practical p-i-n junction design based on ZnO–Al2O3–NiO via a solution process for LT-SOFC electrolyte material and sheds light on the extensive exploration of p-i-n junctions applied in LT-SOFCs.
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高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 14
·9157-9164
·
IF 12.732
Zhiwei Chen,Yang Li,Lin Wang,Yuyu Bu,Jin-Ping Ao
In this paper, a MoS2/Rh–P bi-compound heterogeneous cocatalyst is developed to improve the photoelectrochemical (PEC) water splitting performance of a p-Si photocathode. Compared with the single cocatalysts (MoS2 and Rh–P), the bi-compound heterogeneous cocatalyst MoS2/Rh–P on the p-Si photocathode surface exhibits a much better hydrogen evolution reaction (HER) activity at the electrode/electrolyte interface, which is attributed to the synergistic electronic effect between MoS2 and Rh–P materials. Meanwhile, the TiO2 layer could serve as a linker between p-Si and the surface cocatalyst to optimize the interface energy, further promoting the photocarrier transfer process within the system. Thus, the as-prepared p-Si–TiO2–MoS2/Rh–P photocathode exhibits excellent PEC performance with a high photocurrent density of −24.1 mA cm−2 at 0 V (vs. RHE) and a positive onset potential of 0.43 V (vs. RHE). And the bi-compound heterogeneous cocatalyst provides a feasible strategy for boosting the PEC hydrogen evolution.
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高影响因子
BIORESOURCE TECHNOLOGY
·
2022
·
IF 11.889
Chengqi Feng,Jiatian Zhu,Yajun Hou,Chengrong Qin,Wangqian Chen,Yuhao Nong,Zhangpeng Liao,Chen Liang,Huiyang Bian,Shuangquan Yao
Hemicelluloses were effectively separated using p -toluenesulfonic acid ( p -TsOH) treatment at high temperature. High temperature and pressure promoted hydrolysis of hemicellulose, which limited its value upon recovery. In this study, bagasse hemicellulose was separated and extracted by p -TsOH treatment at atmospheric pressure. The effects of temperature, p -TsOH concentration, and time on hemicellulose separation and extraction were investigated. The optimal conditions were 80 °C, 3.0% p -TsOH, and 120 min. The separation and extraction yield of hemicellulose was 73.23% and 36.02%, respectively. Extraction hemicellulose with 95.60% purity was obtained. In addition, the dissolution mechanism of hemicellulose was analyzed. Degradation of β-glycosidic bonds was inhibited. Benzyl ether bond between carbohydrates and lignin was selectively cleaved. The skeleton structure of xylan in hemicellulose was protected while the functional groups of branch chain were severely damaged. It provides a valuable theoretical basis for the efficient separation and extraction of hemicellulose.
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PubMed
高影响因子
Frontiers in Chemistry
·
2022
·
IF 5.545
Su Ruobing,Tang Hongliang,Xi Fengna
Convenient, rapid and sensitive detection of p-nitrophenol (p-NP), one of the priority environmental pollutants, in environmental samples is of great significance. Electrochemical sensor with simple fabrication process, high sensitivity and selectivity, good antifouling, and regeneration performance is highly desirable. Herein, an electrochemical sensing platform is demonstrated based on the integration of vertically-ordered mesoporous silica-nanochannel film (VMSF) on electrochemical pre-activated glassy carbon electrode (p-GCE), which is able to realize ultrasensitive detection of p-NP in environmental samples. Electrochemical pre-activation of GCE is achieved through a simple and green electrochemical polarization process including anodic oxidation at high voltage and the following cathodic reduction at low voltage. The p-GCE possesses enhanced active area and introduced active sites, and enables stable binding of VMSF. VMSF is easily grown on p-GCE through the electrochemically assisted self-assembly (EASA) method within 10 s. Owing to the hydrogen bonding between silanol groups and p-NP, VMSF nanochannels display strong enrichment effect for the detection of p-NP. The developed VMSF/p-GCE sensor can achieve sensitive detection of p-NP ranging from 10 nM to 1 μM and from 1 to 30 μM with a limit of detection (LOD) of 9.4 nM. Considering the antifouling ability of VMSF, detection of p-NP in pond water is achieved.
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PubMed
高影响因子
PEST MANAGEMENT SCIENCE
·
2022
·Vol. 78
·期 6
·2240-2249
·
IF 4.462
Tan Dai,Zhiwen Wang,Xingkai Cheng,Huige Gao,Li Liang,Pengfei Liu,Xili Liu
BACKGROUND Fungicide resistance has become a serious problem for different mode of action groups except for uncouplers, which makes their resistance mechanism a hot topic, which until now, has not been well clarified. SYP-14288, a newly developed diarylamine fungicide modeled on fluazinam, has shown good toxicity to both oomycete and fungus by the action of uncoupling. In this research, the resistance of Phytophthora capsici to SYP-14288 was studied to clarify the resistance mechanism of uncouplers. RESULTS The toxicity tests of resistant strains against SYP-14288 showed multidrug resistance. The high-performance liquid chromatography (HPLC) results showed that resistant strains could efflux the fungicide, and this ability could be inhibited by the efflux pump inhibitor amitriptyline. The target protein of amitriptyline is P-glycoprotein (P-gp), which was overexpressed in resistant strains. Three products of nitrate reduction of SYP-14288 were detected and determined by HPLC-Q-TOF. Eight cytochrome P450 monooxygenase (P450) proteins were differentially involved in the reduction reaction. CONCLUSION Both fungicide efflux and detoxification metabolism were involved in the resistance mechanisms of P. capsici to SYP-14288. © 2022 Society of Chemical Industry.
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高影响因子
RSC Advances
·
2015
·Vol. 5
·期 97
·79342-79347
·
IF 3.84
Xingrong Xiao,Hui Yang,Nuoxin Xu,Liang Hu,Qilong Zhang
Ag@TiO2 core–shell nanoparticles were synthesized as fillers using a simple vapor-thermal method. Based on the nanoparticles, the P(VDF-HFP)/Ag@TiO2 hybrid films were first prepared by embedding Ag@TiO2 nanoparticles in a poly(vinylidene fluoride co-hexafluoropropylene) [P(VDF-HFP)] matrix. Microstructural and thermal analysis confirmed that Ag nanoparticles had been successfully coated by TiO2 shells and that the thickness of the shell layer was about 8–10 nm. The Ag@TiO2 nanoparticles act as nucleation sites to promote crystallization of the polymer matrix without changing its structure. The P(VDF-HFP)/Ag@TiO2 composite exhibited enhanced dielectric properties over a wide frequency range, and the dielectric permittivity of the polymer nanocomposites is enhanced by ∼300% over the P(VDF-HFP) matrix at a low filler loading of 10 vol%. Moreover, P(VDF-HFP)/Ag@TiO2 also exhibit a higher dielectric constant than P(VDF-HFP)/Ag, P(VDF-HFP)/TiO2 and P(VDF-HFP)/Ag/TiO2 blend composites while maintaining a low loss tangent (below 0.03 at 1 kHz) to achieve a duplex polarization effect.
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高影响因子
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