Small
·
2018
·Vol. 14
·期 38
·1801754
·
IF 9.598
Wen Liu,Miaoliang Ruan,Yanming Wang,Rongguang Song,Xin Ji,Jiake Xu,Jian Dai,Wei Xue
Red blood cell (RBC) membrane-cloaked nanoparticles, reserving the intact cell membrane structure and membrane protein, can gain excellent cell-specific functions such as long blood circulation and immune escape, providing a promising therapy nanoplatform for drug delivery. Herein, a novel RBC membrane biomimetic combination therapeutic system with tumor targeting ability is constructed by embedding bovine serum albumin (BSA) encapsulated with 1,2-diaminocyclohexane-platinum (II) (DACHPt) and indocyanine green (ICG) in the targeting peptide-modified erythrocyte membrane (R-RBC@BPtI) for enhancing tumor internalization and synergetic chemophototherapy. R-RBC@BPtI displays excellent stability and high encapsulation efficiency with multiple cores enveloped in the membrane. Benefited from the stealth functionality and targeting modification of erythrocyte membranes, R-RBC@BPtI can significantly promote tumor targeting and cellular uptake. Under the near-infrared laser stimuli, R-RBC@BPtI presents remarkable instability by singlet oxygen and heat-mediated cleavage so as to trigger effective drug release, thereby achieving deep penetration and accumulation of DACHPt and ROS in the tumor site. Consequently, R-RBC@BPtI with tumor-specific targeting ability accomplishes remarkable ablation of tumors and suppressed lung metastasis in vivo by photothermal and chemotherapy combined ablation under phototriggering. This research provides a novel strategy of targeted biomimetic nanoplatforms for combined cancer chemotherapy–phototherapy.
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高影响因子
CARBON
·
2018
·
IF 7.082
Kui Li,Miao Sun,Wei-De Zhang
Polycyclic aromatic compounds with strong conjugated effect, possess the advantage of improving electronic polarizability , thus accelerating the electron transportation. Here, a facile copolymerization between urea and polycyclic aromatic compounds (benzoic acid, naphthoic acid and anthroic acid) has been applied to constructing aromatic rings-grafted graphitic carbon nitride (GCN) photocatalysts . Incorporation of aromatic rings in the GCN network is an effective protocol to extend its π-conjugated system for visible light harvesting and improves the charge transfer efficiency for prolonging lifetime of photogenerated charge carriers in photocatalytic reactions. The corresponding characterization methods demonstrate that the aromatic rings-modified GCN can effectively narrow the bandgap to favor broad band visible light absorption and suppress recombination of electrons and holes. Remarkably, the moderate conjugated effect of aromatic rings (naphthalene) is crucial to promote charge separation. The developed naphthalene-grafted GCN achieves the highest water splitting performance with hydrogen evolution rate up to 102.1 μmol h −1 , nearly 3.5 times of that of the GCN, and apparent quantum efficiency reaches 5.6% at 450 nm. This finding reveals that the conjugated effect of aromatic rings is significant to control photocatalytic property and brings new ideas for designing aromatic system-modified GCN as highly active photocatalysts towards solar-to-chemical energy conversion.
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Journal of Materials Chemistry A
·
2013
·Vol. 1
·期 20
·6138-6144
·
IF 0
Hongye Zhang,Yanfei Zhao,Sha Chen,Bo Yu,Jilei Xu,Huanjun Xu,Leiduan Hao,Zhimin Liu
Ti3+ self-doped TiOx@anatase core–shell structures were prepared via hydrolysis of Ti2(SO4)3 around TiO particles, followed by post-calcination at temperatures from 723 to 823 K. The as-prepared TiOx@anatase was examined by means of transmission electronic microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. It was demonstrated that the samples displayed core–shell structures with the shell in the anatase form and the core in the anatase and rutile phases, and a large number of Ti3+ ions were present. Electron paramagnetic resonance analysis indicated that the Ti3+ ions were located throughout the whole sample, including the shell, the core and the interface between the core and the shell. The as-prepared TiOx@anatase core–shell catalysts can absorb visible light and showed good activity for catalyzing the degradation of Rhodamine B under visible light irradiation. In particular, the TiOx@anatase obtained at 773 K showed the best performance, due to the high concentration of well-dispersed Ti3+ ions in the sample.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2014
·
IF 3.552
Ling Jiang,Yunpeng Huang,Tianxi Liu
In this work, the effects of halloysite nanotubes (HNTs) on the visible-light photocatalytic ability of electrospun carbon doped TiO 2 /HNT (C TH) nanofibers have been explored. Structural and morphological investigations demonstrate that incorporation of HNTs into anatase C TH hybrid nanofibers was easily achieved by using sol–gel processing combined with electrospinning approach, thus HNTs could be uniformly embedded in the electrospun nanofibers. The visible-light photocatalytic efficiency of C TH hybrid on the degradation of methyl blue (MB) was greatly enhanced with the combination of moderate amount of HNTs (8%), which was 23 times higher than that of commercial anatase TiO 2 . Mechanism of the enhancing effect of HNTs has been explored by analyzing the dual-effect of adsorption and photocatalysis in various amounts of HNTs incorporated C TiO 2 nanofibers. With nanotubular structure and considerable adsorption ability, incorporated HNTs functioned as porogen agent in C TH nanofibers. This simple incorporation approach increases the specific surface areas of nanofibers, which improves the mass transport of reactant into the nanofibers and the adsorption of visible-light by scattering, meanwhile may suppress the charge recombination and enhance photoinduced charge separation, thus efficiently enhancing visible-light photocatalytic performance of the C TH hybrid nanofibers.
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高影响因子
CHEMICAL COMMUNICATIONS
·
2014
·Vol. 50
·期 21
·2755-2757
·
IF 6.718
Zhao Zhao,Huaqiao Tan,Haifeng Zhao,Yang Lv,Li-Jing Zhou,Yujiang Song,Zaicheng Sun
Stable reduced TiO2 rutile nanorods with well-defined facets were prepared by a solvothermal route in the presence of Zn powder. The oxygen vacancy in the TiO2 nanorods, which can be tuned by the amount of Zn, results in a narrow band gap and visible-light photocatalytic activity.
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高影响因子
Biomaterials Science
·
2015
·Vol. 4
·期 2
·338-345
·
IF 3.831
Sheng Wang,Weitao Yang,Jing Cui,Xue Li,Yan Dou,Lin Su,Jin Chang,Hanjie Wang,Xiaodong Li,Bingbo Zhang
The side effects of antitumor drugs and low treatment efficacy are two major challenges of current chemotherapy. To address these issues, we developed a new kind of smart nanocarriers that combine pH-responsive chemotherapy and near-infrared (NIR) light triggered photodynamic therapy. These nanocarriers were based on upconversion nanoparticle (UCN)-loaded folate-conjugated polymeric lipid vesicles (UFPLVs). Merocyanine 540 (MC540), as a photosensitizer, was loaded in the UFPLVs; doxorubicin hydrochloride (DOX), as an antitumor drug, was conjugated to the surfaces of UFPLVs by pH-sensitive hydrazone bonds. The newly developed MC540&DOX–UFPLVs had a nanosized structure with targeting ligand modification, so they had the potential to accumulate into tumor sites via a combination of passive and active targeting effects. An in vitro singlet oxygen test showed that the nanocarriers can generate cytotoxic singlet oxygen successfully under the irradiation of NIR light. In vitro DOX release profiles demonstrated that the nanocarriers can achieve a pH-triggered drug release. It has been demonstrated by a cellular uptake study that the nanocarriers can efficiently deliver drugs and photosensitizers into tumor cells. In vitro and in vivo combination treatments evidenced the high antitumor effects of MC540&DOX–UFPLVs under NIR light irradiation. These results suggest that the MC540&DOX–UFPLVs may be promising nanocarriers for tumor combination therapy applications.
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高影响因子
RSC Advances
·
2014
·Vol. 4
·期 88
·47615-47624
·
IF 3.708
Ping Li,Chunbo Liu,Guoling Wu,Yang Heng,Shuang Lin,Ao Ren,Kehan Lv,Lisong Xiao,Weidong Shi
In this paper, Fe-doped SrTiO3 (FSTO) photocatalysts were successfully prepared via a facile solvothermal method, and their photocatalytic activities for degrading tetracycline (TC) under visible light irradiation were examined. It was found that doping Fe3+ into the lattice of SrTiO3 resulted in the formation of new absorption bands in the visible light region, and the energy band gap decreased from 3.2 eV to 2.6 eV with Fe3+ doping amounts of 0 to 5 wt%. The photocatalytic experimental results indicated that the as-prepared FSTO photocatalysts generate an extremely high enhancement in the TC degradation ratio compared to the pure SrTiO3 under visible light irradiation. In particular, the FSTO sample doped with 3% Fe exhibited the highest TC degradation ratio (71.6%) in 80 min, which is mainly attributed to the narrowed gap generated by the appropriate level of Fe3+ doping. This work suggests that this doping method should be applicable for exploiting other efficient visible light-driven photocatalysts with wide band gap semiconductors.
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高影响因子
RSC Advances
·
2014
·Vol. 4
·期 68
·36040-36045
·
IF 3.708
Yan Liu
Composites of titanium dioxide–reduced graphene oxide (TiO2–RGO) have been prepared via an efficient and facile hydrothermal reaction of graphene oxide and Ti(OH)4 in a ethanol–water solvent. The structure and composition of the composites have been characterized by X-ray diffraction, Scanning electron microscopy, Brunauer–Emmett–Teller specific area analysis, X-ray photoelectron spectroscopy and ultraviolet-visible diffuse reflectance spectroscopy. The results showed that the TiO2–RGO composites exhibited a layered structure with well-dispersed anatase TiO2 on the surface of the reduced graphene oxide. Compared with the pure TiO2 nanoparticles, the composites had larger surface area, and extended the photoresponse range to the visible light region. The photocatalytic activity of the composites was much higher than that of TiO2 in the photodegradation of methyl orange (MO) under visible light irradiation.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2014
·
IF 3.552
Zhenyan Liu,Yue-E. Miao,Mingkai Liu,Qianwei Ding,Weng Weei Tjiu,Xiaoli Cui,Tianxi Liu
A simple and practical strategy has been developed for preparing polyaniline (PANi) coated TiO 2 /SiO 2 nanofiber membranes by a combination of electrospinning, calcination and in situ polymerization. TiO 2 /SiO 2 (TS) nanofibers are fabricated by electrospinning, followed by calcination. Then they are used as template for in situ polymerization of aniline monomers. SEM images show that PANi nanoparticles thus formed can be densely and uniformly coated on the surface of TS nanofibers. Photocatalytic degradation tests show that the as-prepared nanofiber membranes exhibit enhanced photocatalytic activity for degradation of methyl orange under visible light , which may be due to the synergistic effect of PANi and TiO 2 . Furthermore, the effect of polymerization time on the morphology and photocatalytic activity of the membrane is investigated. The free-standing membrane is flexible and easy to handle, which is promising for potential applications in photocatalysis and water remediation fields.
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高影响因子
Advanced Science
·
2015
·Vol. 2
·期 12
·1500116
·
IF 0
Lin Mei,Haitao Zhao,Bingan Lu
Recently, a growing amount of effort has been devoted to solving the widespread problem of pollution. Photocatalysts have attracted increasing attention for their widespread environmental applications. Here, a classic and simple electrospun technique is used to directly fabricate a porous a tungsten oxide nanoframework with graphene film as a photocatalyst for degradation of pollutants. The as-synthesized film simultaneously possesses substantial adsorptivity of aromatic molecules, extensive light absorption range, significant light trapping, and efficient charge carrier separation properties, which remarkably enhance photocatalytic activity. In the photodegradation of Rhodamine B, a significant photocatalytic enhancement in the reaction rate is observed, which has superior photocatalytic activity compared to other bare WO 3 and TiO 2 nanomaterials under visible-light irradiation.
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Journal of Materials Chemistry A
·
2015
·Vol. 3
·期 30
·15710-15714
·
IF 7.443
Ming Wu,Jun-Min Yan,Xue-Wei Zhang,Ming Zhao,Qing Jiang
Ag2O modified g-C3N4 (Ag2O/g-C3N4) was synthesized by a facial hydrothermal reaction. The as-prepared Ag2O/g-C3N4 shows efficient photocatalytic properties for hydrogen evolution from water splitting under visible light irradiation. The rate is about 274 times higher than that of pure g-C3N4, and is even better than that of Pt/g-C3N4. More importantly, Ag2O/g-C3N4 also demonstrates a relatively good recycling stability for photocatalytic hydrogen evolution.
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高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Xiaojiao Kang,Yanchun Yang,Lan Wang,Song Wei,Daocheng Pan
Cadmium-free and water-soluble AgInS2/ZnS core/shell quantum dots (QDs) with a cost of 2.5 $/g are synthesized in an electric pressure cooker. The QD powders with different Ag/In ratios exhibit bright yellow, orange, and orange-red luminescence under UV light. Their absolute photoluminescence quantum yields (PLQYs) can reach as high as 50.5, 57, and 52%, respectively. Because gelatin is used as the capping agent, the concentrated QDs/gelatin solution can be directly utilized as phosphor for the fabrication of white light-emitting diodes (LEDs) by a simple drop-drying process without the need of resin package. Warm-white LEDs are obtained by combining orange-emitting QDs with blue InGaN chip. As-fabricated warm-white LED exhibits a luminous efficacy of 39.85 lm/W, a correlated color temperature (CCT) of 2634 K and a color rendering index (CRI) of 71 at a drive current of 20 mA. Furthermore, the electroluminescence (EL) stability of LED device and thermal stability of as-prepared QDs are evaluated.
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高影响因子
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