JOURNAL OF ALLOYS AND COMPOUNDS
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2019
·
IF 4.175
Yuefeng Liu,Jun Zhao,Yan Zhang,Huafang Zhang,Zhenlong Zhang,Huiping Gao,Yanli Mao
Upconversion nanoparticles (UCNPs) doped with lanthanide ions have potential applications in biomedical, solar cells and displays. However, the intensity of the upconversion luminescence (UCL) is limited by the surface effects of nanomaterials , lattice defects, etc. Here, a novel α-NaErF 4 hollow nanocube is fabricated by using divalent manganese ions (Mn 2+ ) to substitute trivalent erbium ions (Er 3+ ) in the NaErF 4 matrix. The hollow-shell structure can weaken the luminescence quenching and surface quenching effects, reduce the energy loss of higher energy levels in nanoparticles , and improve the light capture ability of nanoparticles. So the UCL of α-NaErF 4 hollow nanocubes is greatly improved, which is 14, 790 and 1071 times higher than that of the β-NaErF 4 under 808, 980 and 1530 nm laser excitation, respectively, and the emission in the red region is enhanced respectively by 69, 2049 and 2902 times. In particular, the hollow nanocubes emit intense single-band red emission under the three different wavelengths, respectively. Moreover, the magnetization of α-NaErF 4 hollow nanocubes is 2.16 emu g −1 at room temperature, which is larger than that of gadolinium-based materials. Hollow-shell structure, excellent paramagnetism and single-band red upconversion emission excited by various wavelengths will create NaErF 4 :40Mn UCNPs a good application prospect in the biomedical field.
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JOURNAL OF FOOD PROCESS ENGINEERING
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2019
·Vol. 42
·期 5
·e13088
·
IF 1.448
Cheng Li,Xiao-Lin Qiu,Li-Xin Lu,Ya-Li Tang,Qing Long,Jin-Gui Dang
In this study, synergetic and controlled-release low-density polyethylene (LDPE) antioxidant active films were prepared by cast extrusion. A well-ordered (4 nm) Mobil Composition of Matter No. 41 (MCM-41) was prepared to carry α-tocopherol for reducing the diffusivity ( D ), while improving the D of quercetin. Characterization of MCM-41 included small angle X-ray scattering, scanning electron microscopy, Fourier transform infrared spectroscopy, and nitrogen adsorption/desorption testing. New films added α-tocopherol and α-tocopherol loaded with MCM-41 on the base of a LDPE film containing quercetin. Testing of new films covered the physical properties, release behavior, and 2,2-diphenyl-1-picrylhydrazyl free radical-scavenging assays. The physical properties discussed differences among any additives, which contain mechanical and barrier properties. Release experiments showed the controlled-release of MCM-41 to α-tocopherol, while addition of α-tocopherol promoted the release of quercetin in food simulant (95% ethanol). Free radical scavenging increased obviously after adding α-tocopherol and α-tocopherol loaded with MCM-41. This study demonstrated the feasibility of synergetic and controlled-release antioxidant active packaging films. Practical Application This work provides a method to control the release of α-tocopherol in the packaging films using molecular sieve MCM-41, and promotes the release of quercetin. The preservation of easily oxidized fatty foods is very important. In addition to the usual high-barrier composite packaging, the release-type antioxidant packaging is also a method. Food antioxidant packaging film is an important research direction in the field of intelligent packaging, and has great potential in the field of food flexible packaging. Release-type antioxidants are added to the packaging substrate, and the release rate of antioxidants is adjusted to prevent the oxidation of contents, to extend the shelf life of butter, and other commodities in the process of commodity storage and transportation.
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Molecular Medicine Reports
·
2018
·Vol. 19
·期 2
·841-850
·
IF 1.922
Guangwei Liu,Jiangkai Liu,Linping Pian,Songlin Gui,Baoping Lu
α‑lipoic acid (ALA) is a naturally occurring antioxidant with protective effects against various hepatic injuries. The aim of the present study was to investigate the mechanisms by which ALA protects the liver from carbon tetrachloride (CCl4)‑induced liver cirrhosis. The widely used liver cirrhosis rat model was established via an intraperitoneal injection of 2 mg/kg 50% CCl4, three times/week for 8 weeks. Simultaneously, 50 or 100 mg/kg ALA was orally administrated to the rats every day for 8 weeks. The activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) was detected in the serum. The pathological liver injuries were analyzed using hematoxylin and eosin and Masson's trichrome staining. The principal factors involved in the transforming growth factor‑β (TGF‑β)/mothers against decapentaplegic homolog 9 (Smad3) and protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathways and in autophagy were examined using reverse transcription‑quantitative polymerase chain reaction or western blot analysis. The results demonstrated that the administration of ALA alleviated CCl4‑induced liver injury, as demonstrated by decreased ALT and AST activity, improved pathological injuries and reduced collagen deposition. The CCl4‑induced increase in TGF‑β and phosphorylated‑Smad3 expression levels was additionally inhibited by treatment with ALA. Furthermore, the administration of ALA reversed the CCl4‑induced upregulation of light chain 3II and Beclin‑1, and downregulation of p62. The CCl4‑induced suppression of the AKT/mTOR pathway was additionally restored following treatment with ALA. In combination, the results of the present study demonstrated that ALA was able to protect CCl4‑induced liver cirrhosis, an effect that may be associated with inactivation of the TGF‑β/Smad3 pathway and suppression of autophagy.
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JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2019
·
IF 3.47
Adel Baimoldina,Konstantinos Papadikis,Elena Yu. Konysheva
The feasibility of α-Fe 2 O 3 catalyst addition in the in-situ catalytic fast pyrolysis of Pinewood was considered with the focus on the variation in its shape: nano-sized non-ideal spheres, nanotubes, hollow nano/microtubes, and octadecahedral crystals. Nano-sized spheres strongly promoted the formation of acetaldehyde, something that was also observed for the octadecahedral crystals. The formation of acids was primarily facilitated through the addition of nanotube catalysts and octadecahedral crystals. Newly formed alicyclic ketonic compounds were promoted through the addition of nano-sized spheres, hollow nano/microtubes, and octadecahedral crystals. The latter two catalysts also showed a moderate selectivity in the formation of furfural. All applied catalysts showed loss of activity, though at different degrees, on the formation of lignin derived phenolic compounds, which can be primarily attributed to favoring the formation of char with simultaneous release of CO 2 . All used α-Fe 2 O 3 catalysts with different shapes maintained their original morphology after the rapid heating with the rate of 20 K/ms followed by catalytic fast pyrolysis at 500 °C, indicating that nanomaterials with targeted dimensions can be applied as catalysts in the catalytic fast pyrolysis of biomass to enhance conversion of undesired oxygenated compounds to higher quality bio-oil and valuable chemicals.
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COMPOSITES PART B-ENGINEERING
·
2019
·
IF 6.864
Jiangtao Xu,Songmin Shang,Shouxiang Jiang
Conventionally, the surface-enhanced Raman spectroscopy (SERS) measurement is performed by dispersing noble metal nanoparticles onto the target sample directly or assembling noble metal nanoparticles onto a micro-sized substrate. Despite it is flourishing, this method is not adequate for various samples, mainly limited by either a defined confinement of the test position or the complex extraction process of the target sample on the irregularly shaped surface, besides the costive materials, complex and uncontrollable fabricating processes. Herein, we demonstrate that the α-Fe 2 O 3 thin film is decorated with Ag nanoparticles constructed on SiO 2 fibers as a flexible SERS-active substrate, which yields a functional optical enhancement of the signal at 532 nm laser excitation . It shows a high enhancement factor of 4.71 × 10 5 , ultrahigh sensitivity of 10 −15 M, and excellent signal stability with a relative standard deviation (RSD) of 1.22% and reproducibility with a RSD of 0.258%.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2018
·Vol. 29
·期 13
·11178-11186
·
IF 2.324
Cheng Yali,He Yue,Li Shuo,Wang Yifang,Zhao Yan,Li Yu,Li Haiying,Liu Li
In the present work, the acetone gas sensing material based on pure α-Fe 2 O 3 nanotubes, pure and Cu-doped α-Fe 2 O 3 porous nanotubes were fabricated by electrospinning and annealing processes. Different Cu dopant concentrations are introduced to investigate the dopant’s role in sensing performance. The structures and chemical compositions of the as-prepared products were examined using a series of material characterization methods including XRD, EDS, SEM and nitrogen adsorption–desorption analysis. And the acetone sensing results demonstrate that the gas sensitivity of porous nanotubes is better than nanotubes. Moreover, compared with pure samples, the sensor based on 3.0 wt% Cu-doped α-Fe 2 O 3 porous nanotubes exhibits higher response (99.43/100 ppm) and excellent selectivity towards acetone at 164 °C. Meanwhile, the detection limit can extend down to ppb level (2.2/100 ppb). Additionally, the sensor also shows fast response and recovery time (5/18 s) and good repeatability to acetone. The enhancement of gas sensitivity is ascribed to not only the effective utility of hollow and porous structures, but also the high catalytic activity of the Cu additive.
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Frontiers in Bioengineering and Biotechnology
·
2024
·
IF 4.3
Feng Kai,Di Ya,Han Meng,Yan Weitao,Guo Yulin,Huai Xiangqian,Wang Yimin
A novel photoelectrochemical (PEC) aptasensor based on a dual Z-scheme α-Fe2O3/MoS2/Bi2S3 ternary heterojunction for the ultrasensitive detection of circulating tumor cells (CTCs) was developed. The α-Fe2O3/MoS2/Bi2S3 nanocomposite was prepared via a step-by-step route, and the photoproduced electron/hole transfer path was speculated by conducting trapping experiments of reactive species. α-Fe2O3/MoS2/Bi2S3-modified electrodes exhibited greatly enhanced photocurrent under visible light due to the double Z-scheme charge transfer process, which met the requirement of the PEC sensor for detecting larger targets. After the aptamer was conjugated on the photoelectrode through chitosan (CS) and glutaraldehyde (GA), when MCF-7 cells were presented and captured, the photocurrent of the PEC biosensing system decreased due to steric hindrance. The current intensity had a linear relationship with the logarithm of MCF-7 cell concentration ranging from 10 to 1×105 cells mL−1, with a low detection limit of 3 cell mL−1 (S/N = 3). The dual Z-scheme α-Fe2O3/MoS2/Bi2S3 ternary heterojunction-modified PEC aptasensor exhibited high sensitivity and excellent specificity and stability. Additionally, MCF-7 cells in human serum were determined by this PEC aptasensor, exhibiting great potential as a promising tool for clinical detection.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2016
·
IF 5.393
Ting Liu,Lucheng Xue,Xin Guo,Jia Liu,Yu Huang,Chuguang Zheng
The reaction mechanisms of a mixture gas of HCl, O2, and SO2 in Hg0 adsorption on α-Fe2O3(001) surface are clarified by a group of adsorption experiments and theoretical calculations based on the density functional theory. The role of O2 in removing Hg0 is greatly influenced by the reaction temperature, meanwhile, the O atom coverage could affect the adsorption performance of Hg0. The dissociated O2 competes with the active sites of Cl species on Fe surface at low temperature, however, at medium temperature HCl and O2 could simultaneously facilitate the Hg0 transformation. Combined with the theoretical calculations, the role of SO2 and the probable pathways in removing Hg0 are discussed. Lower concentration of SO2 as well as HCl could dissociate on α-Fe2O3(001) surface, and the intermediates combine with gaseous Hg0, forming mercury–sulfur, mercury–chlorine compounds, and so forth. In addition, the different concentrations of SO2 are also discussed, and the corresponding X-ray photoelectron spectroscopy analysis on contrasted samples is conducted to research the morphological characterization, providing a reliable basis for judging the probable pathways of Hg0 transformation.
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DALTON TRANSACTIONS
·
2016
·Vol. 45
·期 27
·11129-11136
·
IF 4.177
Yue Su,Xiuling Liu,Pengpeng Lei,Xia Xu,Lile Dong,Xianmin Guo,Xingxu Yan,Peng Wang,Shuyan Song,Jing Feng,Hongjie Zhang
Core–shell–shell heterostructures of α-NaLuF4:Yb/Er@NaLuF4:Yb@MF2 (M = Ca, Sr, Ba) have been successfully fabricated via the thermal decomposition method. Upconversion nanoparticles (UCNPs) were characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), upconversion luminescence (UCL) spectroscopy, etc. Under 980 nm excitation, the emission intensities of the UCNPs are remarkably enhanced after coating the MF2 (M = Ca, Sr, and Ba) shell. Among these samples, CaF2 coated UCNPs show the strongest overall emission, while BaF2 coated UCNPs exhibit the longest lifetime. These results demonstrate that alkaline earth metal fluorides are ideal materials to improve the UCL properties. Meanwhile, although the lattice mismatch between the ternary NaREF4 core and the binary MF2 (M = Sr and Ba) shell is relatively large, the successfully synthesized NaLuF4:Yb/Er@NaLuF4:Yb@MF2 indicates a new outlook on the fabrication of heterostructural core–shell UCNPs.
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JOURNAL OF CHROMATOGRAPHY A
·
2016
·
IF 3.926
Lei Tan,Rong He,Yongxian Li,Yong Liang,He Li,Youwen Tang
α-Amanitin and β–amanitin are the main toxins of mushroom poisoning. The application of traditional non-selective adsorbents is not satisfactory in clinical treatment of amanita mushroom poisoning due to lack of specificity adsorption capability of these adsorbents toward amanitin toxins. In the current work, we introduce a novel molecularly imprinted biomimetic adsorbent based on a ligand specificity determinant through surface imprinted strategy. Owing to the expensive price of the amanitin sources, we selected a typical common moiety of α, β–amanitin as specificity determinant to synthesize a template necessary for the preparation of molecularly imprinted polymers (MIPs). Computer simulation was used to initially select acidic methacrylic acid (MAA) and basic 4-vinyl pyridine (4-VP) together as functional monomers. The experiments further demonstrated that the synergistic interaction of MAA and 4-VP played a primary role in the recognition of α, β-amanitin by MIPs. By means of batch and packed-bed column experiment and the hemocompatibility evaluation, the resultant biomimetic adsorbent has been proved to be capable of selectively removing α, β–amanitin and possess good hemocompatibility. This novel adsorbent has great potential to find application in human plasma purification.
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MOLECULES
·
2016
·Vol. 21
·期 9
·1148
·
IF 2.465
Shuxia Yan,Xianan Zhang,Xin Wen,Qiang Lv,Changjie Xu,Chongde Sun,Xian Li
Chinese bayberry (Morella rubraSieb. et Zucc.) fruit have a diverse flavonoid composition responsible for the various medicinal activities, including anti-diabetes. In the present study, efficient simultaneous purification of four flavonoid glycosides, i.e., cyanidin-3-O-glucoside (1), myricetin-3-O-rhamnoside (2), quercetin-3-O-galactoside (3), quercetin-3-O-rhamnoside (4), from Chinese bayberry pulp was established by the combination of solid phase extract (SPE) by C18 Sep-Pak®cartridge column chromatography and semi-preparative HPLC (Prep-HPLC), which was followed by HPLC and LC-MS identification. The purified flavonoid glycosides, as well as different fractions of fruit extracts of six bayberry cultivars, were investigated for α-glucosidase inhibitory activities. The flavonol extracts (50% methanol elution fraction) of six cultivars showed strong α-glucosidase inhibitory activities (IC50= 15.4–69.5 μg/mL), which were higher than that of positive control acarbose (IC50= 383.2 μg/mL). Four purified compounds1–4exerted α-glucosidase inhibitory activities, with IC50values of 1444.3 μg/mL, 418.8 μg/mL, 556.4 μg/mL, and 491.8 μg/mL, respectively. Such results may provide important evidence for the potential anti-diabetic activity of different cultivars of Chinese bayberry fruit and the possible bioactive compounds involved.Keywords:Morella rubrafruit;α-glucosidase inhibitory activity;flavonoid glycosides;purification
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JOURNAL OF ORGANIC CHEMISTRY
·
2014
·
IF 4.638
Zhiguo Zhang,Qing Tian,Jingjing Qian,Qingfeng Liu,Tongxin Liu,Lei Shi,Guisheng Zhang
An efficient and Brønsted acid free one-pot protocol to directly generate structurally sophisticated α-formylpyrrole derivatives in moderate to good yields has been demonstrated, involving an iron-mediated domino oxidation/formylation reaction of readily available 2,3-dihydro-1H-pyrroles in dimethyl sulfoxide and air atmosphere, in which dimethyl sulfoxide acts as the formyl donor. A possible mechanism is presented.
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危险品化学品经营许可证（带存储）