ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Xinyuan Lyu,Luchao Ren,Le Xin,Zhengxin Li,Xianxin Zhang,Zheng Luo,Pengchao Shao,Yuxiao Zhang,Panpan Lyu,Mingwei Zhang
Fabrication of low-temperature co-fired ceramic (LTCC) densified at a low sintering temperature (<900 °C) is energy saving and environmentally friendly. Here, an interesting attempt has been made to lower the sintering temperature of MgGa2O4 by adding CuMoO4 for LTCC application. The sintering temperature of MgGa2O4 was remarkably reduced from 1410 to 900 °C, which contributed to energy saving. Furthermore, a series of studies on microstructure, sintering behavior, lattice parameters, and microwave dielectric characteristic of the samples were carried out. The occurrence of ion substitution between MgGa2O4 and CuMoO4, which affected the sintering densification, ionic polarizability, and Mg–O bond length, made the composites present various sintering and dielectric properties. Moreover, the full width half maximum (FWHM) value of the T2g peak in Raman spectra and lattice distortion were also analyzed to reveal the intrinsic interaction between structure and dielectric properties. Finally, the 0.5MgGa2O4–0.5CuMoO4 ceramics sintered at 900 °C showed the best comprehensive performance, εr = 6.8, Q × f = 15,800 GHz, τf = −54.2 ppm/°C. These promising properties make the composite more suitable for practical application.
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高影响因子
PROCESS BIOCHEMISTRY
·
2023
·
IF 4.4
Xiaoxue Zhang,Mengmeng Zhong,Rui Zhou,Wenxiu Qin,Youbin Si
Microbial reduction of Se(IV) to Se(0) is extremely important for the detoxification of selenium oxyanion, but the reductive mechanism is still controversial. In this study, the reduction of Se(IV) by Shewanella oneidensis MR-1 and Shewanella putrefaciens was systematically investigated. The results showed that excessive Se(IV) severely inhibited the growth of microorganisms and Se(IV) reduction. The extracellular accumulation of Nano-Se(0) particles was shown to be approximately 250–650 nm in diameter. Riboflavin facilitated Se(IV) reduction, while rotenone , as an electron inhibitor, could completely inhibit Se(IV) reduction, validating the extracellular electron transport process for biosynthesized Nano-Se(0). Importantly, the amorphous Nano-Se(0) synthesized by S. oneidensis MR-1 were mixtures of helical chains and Se 8 rings, while those synthesized by S. putrefaciens were mainly composed of helical chains. FTIR results demonstrated that Nano-Se(0) particles were wrapped by some proteins, organic substances and lipids , exhibiting superior dispersibility and biocompatibility. Biogenic Nano-Se(0) particles can also be considered for technological applications in various fields.
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高影响因子
JOURNAL OF BIOMATERIALS APPLICATIONS
·
2023
·
IF 2.9
Mengyu Zhu,Yang Zhang,Chi Zhang,Lei Chen,Ying Kuang
Oxidative damage of neurons is one of the key pathological markers of Alzheimer’s disease (AD), which eventually leads to neuronal apoptosis and loss. Nuclear factor E2-related factor 2 (Nrf2) is a key regulator of antioxidant response and is considered to be an important therapeutic target for neurodegenerative diseases. In this study, the selenated derivative of antioxidant rutin (Se-Rutin) was synthesized with sodium selenate (Na2SeO3) as raw material by a simple electrostatic-compound in situ selenium reduction method. The effects of Se-Rutin on H2O2 induced oxidative damage in Pheochromocytoma PC12 cells were evaluated by cell viability, apoptosis, reactive oxygen species level and the expression of antioxidant response element (Nrf2). The results showed that H2O2 treatment significantly increased the level of apoptosis and reactive oxygen species, while the level of Nrf2 and HO-1 decreased. However, Se-Rutin significantly reduced H2O2 induced apoptosis and cytotoxicity, and increased the expression of Nrf2 and HO-1, both of which were better than that of pure rutin. Therefore, the activation of Nrf2/HO-1 signaling pathway may be the basis of Se-Rutin’s anti-oxidative damage to AD.
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PubMed
高影响因子
Reaction Chemistry & Engineering
·
2023
·Vol. 8
·期 9
·2342-2352
·
IF 3.9
Jia Juan,Xue Ping,Liu Xueping,Xu Chongrui,Gu Yaohua,Li Peng
The co-immobilization of laccase and a mediator is essential for water treatment due to the fact that the free laccase and mediator cannot be recovered and reused simultaneously. Herein, a spherical solid biocatalyst, Lac@Ce-GMA-Cu-DA@AS, was prepared via the co-immobilization of laccase and acetosyringone mediator in a functionalized cellulose composite doped with HKUST-1. The Lac@Ce-GMA-Cu-DA@AS microbeads exhibited higher catalytic activity, better reusability and superior degradation efficiency for the substrate compared to the undoped HKUST-1. Specifically, 96% degradation efficiency of carbazole solution with a concentration of 20 mg L−1 was achieved after treatment with 1.0 g (wet weight) of Lac@Ce-GMA-Cu-DA@AS beads for 8 h under the conditions of 30 °C, pH 5.0, and 20 mM ionic strength. Based on the analysis and identification of the degradation intermediates of carbazole, the possible pathways for the degradation of carbazole by the Lac@Ce-GMA-Cu-DA@AS microbeads were proposed. It was found that the toxicity of the carbazole solution was lower after treatment than the original. Natural polymeric cellulose composite doped with HKUST-1 displayed an excellent performance for co-immobilizing laccase–mediator and can provide a practical new approach for the degradation of carbazole pollutant in water.
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高影响因子
IRANIAN POLYMER JOURNAL
·
2023
·Vol. 32
·期 10
·1229-1240
·
IF 3.1
Song Lixin,Zhang Jian,Zhang Xing,Rui Chaofan,Zhang Yunxia,Wang Mingyu,He Juan
The surface imprinting polymers (HKUST-1 @ MIPs) were synthesized by molecular imprinting technology. Using the metal–organic framework (HKUST-1) as the carrier, 4-methylumbelliferyl acetate as alternative templates for aflatoxins, and molecularly imprinted polymers polymerized on the surface of HKUST-1. The adsorption capacity (6.0 μg·mg −1 ) and adsorption rate (adsorption equilibrium reached within 5 min) of HKUST-1 @ MIPs for aflatoxins were studied. HKUST-1 @ MIPs were used as adsorbents to prepare surface-imprinted solid-phase extraction columns (HKUST-1 @ MIPs SPE columns). The extraction conditions of HKUST-1 @ MIPs SPE columns were optimized, and the reliability of the method was verified by HPLC–FD technique. Water was chosen as the wash solution and methanol as the eluent with an elution volume of 2 mL. The linear range of the method was 0.5–20 μg·kg −1 with R 2 = 0.9991–0.9996. The detection limits of aflatoxins (G2, G1, B2, and B1) were 0.05, 0.02, 0.03, and 0.05 μg·kg −1 , respectively. The limits of quantification were 0.2, 0.1, 0.15, and 0.3 μg·kg −1 , accordingly. The spiked recovery of aflatoxins (G2, G1, B2, and B1) was 92.5%-118.4%, and the relative standard deviation was 3.14%-6.03%. It had been verified that the self-made solid-phase extraction column had high stability and reusability and could be used for at least six times. Comparing the HKUST-1 @ MIPs SPE and immunoprophylactic columns, a low-cost, easy-to-operate, and sensitive method was developed for detecting trace aflatoxins in food by combining with HPLC–FD technique. Graphical abstract
In this work, dissolve BTC and Cu (NO3)2·3H2O completely and stir magnetically, heat to 120 °C for 12 hours. After washing with solvent, the purple solid HKUST-1 was obtained by centrifugation and drying
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高影响因子
Crystals
·
2023
·Vol. 13
·期 6
·955
·
IF 2.7
Qi Su,Jingjing Qu,Fei Liu,Changlai Yuan,Xiao Liu,Mingwei Su,Liufang Meng,Guohua Chen
Ti4+-ion-doped (n+ 1)SrO −nCeO2(n= 2) ceramic systems were prepared with the conventional solid-state reaction method, and the effects of the phase structures and compositions, sintering behaviors, microstructures and microwave dielectric properties of these ceramic systems were investigated in detail as a function of TiO2content. The analytical results of the XRD patterns show that the pure (n+ 1)SrO −nCeO2(n= 2) system is a composite-phase ceramic system with coexisting SrCeO3and Sr2CeO4phases (represented as a SrCeO3+ Sr2CeO4system), which belong to the orthogonal structures of the Pmcn (62) and Pbam (55) space groups, respectively. For thexTiO2-(1 − x) (SrCeO3+ Sr2CeO4) (x= 0.1–0.4) ceramic samples, the secondary phase Sr2TiO4can also be detected within the range of the investigated components. Meanwhile, the Raman spectroscopy, SEM-EDS, and HRTEM (SAED) analysis results also verified the correctness and consistency of the phase structures and compositions for all the given specimens. In addition, complex impedance spectroscopy was used to detect the conductive behavior of these compound ceramic systems, and the calculation results show that the appropriate addition of Ti4+-ions can make the SrCeO3+ Sr2CeO4system have better thermal stability. The composition ofx= 0.2 multiphase structural ceramic sample sintered at 1330 °C for 4 h has a near zero τfvalue of ~−4.6 ppm/°C, a moderateεrof ~40.3 and a higherQ×f~44,020 GHz (at 6.56 GHz). The relatively superior-performing ceramics developed in this work are expected to provide a promising microwave dielectric material for communication components.Keywords:phase structures and compositions;SrCeO3+ Sr2CeO4system;TiO2addition;microwave dielectric properties
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高影响因子
IONICS
·
2023
·Vol. 29
·期 9
·3795-3803
·
IF 2.8
Xiong Qinghao,Wan Haifei,Peng Xia,Zhu Yongmei
N-rich carbon (C) microspheres loaded with Ni nanoparticle (NiNP) microspheres (Ni@N-doped C) were obtained by calcination of covalent organic framework (COF) LZU-1 with abundant N atoms/Ni 2+ . Lots of NiNPs with the size of 4 nm are arrayed uniformly and firmly into N-doped C microspheres derived from COF LZU-1 based on the strong coordination between N atoms on the wall of well-ordered pores and Ni atoms, which is more beneficial to rapid electron and mass transfer. The synergistic effect from N-doped C microspheres and small-sized NiNPs in Ni@N-doped C enhances catalytic activity of Ni@N-doped C microspheres greatly, which provides feasibility for the construction of non-enzymatic electrochemical sensor. The non-enzymatic electrochemical sensor based on Ni@N-doped C microspheres is applied to the detection of dopamine (DA) and shows good detection results with a low detection limit of 0.009 μM and a wide detection range of 0.027–70 μM. What is more, this DA sensor has good anti-interference, reproducibility, and stability, which provides new idea for the construction of non-enzymatic electrochemical sensor.
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高影响因子
COMBUSTION AND FLAME
·
2023
·
IF 4.4
Jinhu Liang,Ruining He,Shashank S. Nagaraja,A. Abd El-Sabor Mohamed,Haitao Lu,Yousef M. Almarzooq,Xiaorui Dong,Olivier Mathieu,William H. Green,Eric L. Petersen,S. Mani Sarathy,Henry J. Curran
2,3-Dimethyl-2-butene (TME) is a potential fuel additive with high research octane number (RON) and octane sensitivity ( S ), which can improve internal combustion engine performance and efficiency. However, the combustion characteristics of TME have not been comprehensively investigated. Thus, it is essential to study the combustion characteristics of TME and construct a detailed chemical kinetic model to describe its combustion. In this paper, two high-pressure shock tubes and a constant-volume reactor are used to measure ignition delay times and laminar flame speeds of TME oxidation . The ignition delay times were measured at equivalence ratios of 0.5, 1.0, and 2.0 in “air”, at pressures of 5 and 10 bar, in the temperature range of 950 – 1500 K. Flame speeds of the TME/ “air” mixtures were measured at atmospheric pressure, at a temperature of 325 K, for equivalence ratios ranging from 0.78 to 1.31. Two detailed kinetic mechanisms were constructed independently using different methodologies; the KAUST TME mechanism was constructed based on NUIGMech1.1, and the MIT TME mechanism was built using the Reaction Mechanism Generator (RMG). Both mechanisms were used to simulate the experimental results using Chemkin Pro. In the present work, reaction flux and sensitivity analyses were performed using the KAUST mechanism to determine the critical reactions controlling TME oxidation at the conditions studied.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2023
·
IF 6.8
Rui Yan,Jie Ding,Qianlei Yang,Xiaoyun Zhang,Junyu Han,Tingxu Jin,Shudi Shi,Xirui Wang,Yu Zheng,Heran Li,Hengdong Zhang,Yan An
Skeletal system toxicity due to lead exposure has attracted extensive attention in recent years, but few studies focus on the skeletal toxicity of lead in the early life stages of zebrafish. The endocrine system, especially the GH/IGF-1 axis, plays an important role in bone development and bone health of zebrafish in the early life. In the present study, we investigated whether lead acetate (PbAc) affected the GH/IGF-1 axis, thereby causing skeletal toxicity in zebrafish embryos. Zebrafish embryos were exposed to lead PbAc between 2 and 120 h post fertilization (hpf). At 120 hpf, we measured developmental indices, such as survival, deformity, heart rate, and body length, and assessed skeletal development by Alcian Blue and Alizarin Red staining and the expression levels of bone-related genes. The levels of GH and IGF-1 and the expression levels of GH/IGF-1 axis-related genes were also detected. Our data showed that the LC50 of PbAc for 120 h was 41 mg/L. Compared with the control group (0 mg/L PbAc), after PbAc exposure, the deformity rate increased, the heart rate decreased, and the body length was shortened at various time periods, in the 20-mg/L group at 120 hpf, the deformity rate increased by 50 fold, the heart rate decreased by 34%, and the body length shortened by 17%. PbAc altered cartilage structures and exacerbated bone loss in zebrafish embryos; in addition, PbAc exposure down-regulated the expression of chondrocyte ( sox9a , sox9b ), osteoblast ( bmp2 , runx2 ) and bone mineralization-related genes ( sparc , bglap ), and up-regulated the expression of osteoclast marker genes ( rankl , mcsf ). The GH level increased and the IGF-1 level declined significantly. The GH/IGF-1 axis related genes ( ghra , ghrb , igf1ra , igf1rb , igf2r , igfbp2a , igfbp3 , igfbp5b ) were all decreased. These results suggested that PbAc inhibited the differentiation and maturation of osteoblasts and cartilage matrix, promoted the formation of osteoclasts, and ultimately induced cartilage defects and bone loss by disrupting the GH/IGF-1 axis.
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高影响因子
FOOD AND AGRICULTURAL IMMUNOLOGY
·
2022
·
IF 3.268
Peizhen Li,Xiuhua Xia,Jiannan Chen,Hang Yu,Yunfei Xie,Yahui Guo,Weirong Yao,He Qian,Yuliang Cheng
Gold-coated silver core–shell nanoparticles (Ag@Au NPs) have been widely used for SERS analysis due to plasmon resonance performances. However, it is a great challenge to fabricate Ag@Au core–shell structures with specified morphology. In this paper, the size and shape of Ag NPs (core) were precisely controlled by a seed-mediated approach, and then the gold shell was completely coated on under the strong reduction of ascorbic acid, resulting in Ag@Au NPs with highly regulated morphology. The obtained Ag@Au NPs achieved a similar or even better SERS enhancement factor (EF) (up to 5.7 × 107) compared to Ag NPs, but significantly higher stability. For the rapid SERS detection of nitrofurantoin metabolite AHD, a limit of detection (LOD) as low as 1 × 10−10 M and a wide linear range from 1 × 10−4 to 1 × 10−8 M were obtained. Furthermore, recoveries for crayfish samples were from 90.5% to 108%, indicating a good performance of the presented method in real sample detection.
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高影响因子
Journal of Coatings Technology and Research
·
2019
·Vol. 16
·期 3
·881-893
·
IF 1.584
Wang Xiao-Xin,Cao Yun-Qing,Fu Hong-Li,Jiang Mei-Yan,Hu Ji-Ming
This work aimed at understanding the role of silane pretreatment layer in an organic coating system. The study consists of two parts. In the first part, the anticorrosion performance and interfacial property of silane-pretreated epoxy coatings were studied. The results showed that pretreatment with functional 3-glycidoxypropyl-trimethoxysilane (GPTMS) strongly improves the adhesion of epoxy-coated AA2024-T3 aluminum alloy due to the high interfacial compatibility between silane and epoxy coatings and that pretreatment with nonfunctional bis-1,2-[triethoxysilyl]ethane (BTSE) remarkably reduces the adhesion to the alloy because of low compatibility. Nevertheless, the BTSE film provides higher resistance to corrosion than the GPTMS-pretreated coating system, because the former is more hydrophobic and thicker.
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高影响因子
Molecular Medicine Reports
·
2019
·Vol. 19
·期 3
·1781-1790
·
IF 1.851
Yan Luo,Daogong Zhang,Yueling Chen,Zhongsheng Cao,Zhaomin Fan
The brain‑derived neurotrophic factor (BDNF) and c‑Jun NH 2‑terminal kinase (JNK) signaling pathways are therapeutic targets to prevent degeneration in the central nervous system. Dexamethasone (DXMS), a glucocorticoid, protects against vestibular brain injury, however, the molecular mechanisms have yet to be fully elucidated. To investigate whether the BDNF and JNK signaling pathways are involved in the protective effects of DXMS in rats with vestibular dysfunction, a rat model of severe vestibular deficits was established by middle ear injection of arsanilic acid (AA; 100 mg/ml; 0.05 ml). After 3 days, rat symptoms and behavior scores with vestibular disorders were detected. In brain tissues, histopathological alterations, cell apoptosis, expression levels and patterns of BDNF signaling pathway‑associated BDNF, tyrosine receptor kinase B (TrKB) and K+/Cl‑ cotransporter isoform 2 (KCC2), and the expression of apoptosis‑related cleaved‑caspase 3 and the JNK signaling pathway were detected. It was identified that DXMS relieved AA‑induced vestibular dysfunction, leading to improvement in rat behavior scores to normal levels, minimizing brain damage at the histopatholojnnkngical level, reducing cell apoptosis, enhancing the expression of BDNF, TrKB and KCC2, and downregulating cleaved‑caspase 3 and phosphorylated‑JNK1/2 in brain tissues. Together, these findings indicated the protective effect of DXMS on AA‑induced rat vestibular dysfunction, and that activating BDNF and inhibiting JNK singling pathways were the underlying mechanisms. In addition, with additional treatment of mifepristone (RU486), a specific glucocorticoid agonist, all the events elicited by DXMS mentioned above in the AA‑treated rat rats were reversed. In conclusion, DXMS was identified as a therapeutic agent targeting the BDNF and JNK singling pathways for AA‑induced rat vestibular dysfunction.
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高影响因子
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