INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2022
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IF 8.025
Jingwen Li,Zhongli Yang,Zhicheng Jiang,Mengying Ni,Min Xu
Recently, owing to the wide applications in electronic skin and human activity monitoring, flexible hydrogel strain sensors have attracted great attention. And the better preparation with more efficient is always common aspiration. In this work, acrylamide (AM) was in situ polymerized in chitosan (CS) matrix to prepare hydrogels (PAM@CS). Inspired by the adhesion of natural mussels, plant polyphenol tannic acid (TA) was introduced into the system, Fe 3+ was also introduced as redox agent to perform an ultrafast polymerization, and the composite hydrogel PAM@CS/TA-Fe can be prepared at 60 °C within 1 min. The hydrogels are ion conductive and show good sensing performance in detecting major and subtle body motions. Benefiting from the multiple dynamic noncovalent bonds, the PAM@CS/TA-Fe hydrogels also show excellent adhesion performance and good self-healing property, which would expand their application range in wearable and flexible electronic equipment.
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
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2022
·Vol. 105
·期 8
·5325-5335
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IF 4.186
Jinping Wang,Tariq Shamim,Naila Arshad,Muhammad Sultan Irshad,Muhammad Naveed Mushtaq,Chuankun Zhang,Muhammad Yousaf,Lina Abdullah Alshahrani,M. Akbar,Yuzheng Lu
The world population is severely affected by water scarcity, and it is an alarming issue that needs to be addressed urgently. Seawater desalination by solar-driven evaporation is a promising technique to produce clean water. However, it is energy intensive and directs to a low water yield under natural sunlight. Therefore, the developments of new photothermal materials can reduce required energy for desired evaporation rates for efficient freshwater yield. Indeed, chitosan and polypyrrole-based polymers are natural cationic copolymers, and their nanocomposites present well deal of interest for hydrogel structures due to their hydratable skeletons, and solar-absorbing nature. Here, we report in situ polymerized Fe 2 O 3 @PPy/chitosan hydrogels as lightweight evaporation structures for solar-powered evaporation under brine solutions (3.5 wt%). The polymeric network of Fe 2 O 3 @PPy/chitosan hydrogels builds in cross-linked macroporous water channels, self-floating, and a wide range of omnidirectional solar absorption (96%). The state-of-the-art evaporation experiments demonstrate an efficient evaporation rate of water (1.80 kg m –2 h –1 ) and enhanced solar-to-vapor conversion efficiency (91%) as compared to other carbon-based evaporation structures, excluding heat losses under 1 kW m –2 (one sun). Of note, the ultra-black hydrogel surface stored enough thermal energy (39.6°C) under one sun solar irradiance due to the cationic polymeric network of Fe 2 O 3 @PPy/chitosan. A single-step process for a freshwater supply that has been purified from various contaminants shows the potential of this device for real-world applications.
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POLYMER DEGRADATION AND STABILITY
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2022
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IF 5.204
Chenyu Zhou,Xinyu Wang,Junjie Wang,Zhiquan Pan,Hong Zhou
Improving the flame-retardant efficiency while maintaining the good properties of epoxy resin has become increasing important for industry applications. In this work, a fast char-forming flame retardant (nitro-containing chitosan-derivate, named CSN) derived from a one-pot reaction between chitosan and p-nitrobenzaldehyde was synthesized. When the total addition amount of CSN and 9,10-dihydro-9-oxa-10-phospha-phenanthrene-10-oxide (DOPO) in epoxy resin (EP) is only 5wt%, the cured EP passed the UL-94 V-0 rating and the limit oxygen index (LOI) reached to 34.0%. The total heat release (THR) and total smoke production (TSP) of the modified EP decreased by 23.5% and 77.2%, correspondingly, and the char-forming ability was significantly improved when compared with pure EP. Meanwhile, the CSN and DOPO modified EP maintained comparable tensile strength, flexural strength and transparency with pure EP, which is closely related to the abundant hydroxyl and amine groups as well as rigid structure in CSN and DOPO. Considering that the facile preparation method and small addition amount of the flame retardant, the present work provides a convenient solution for the preparation of modified epoxy resins with good flame retardancy, heat stability, transparency and comparable mechanical properties with pure EP, which is expected to be widely used in industries.
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CARBOHYDRATE POLYMERS
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2022
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IF 10.723
Congwei Li,Lian Duan,Xinjian Cheng
Fluorescent chitosan-based hydrogel for the selective detection and adsorption of Hg 2+ /Hg + in aqueous environment was prepared through three-step synthesis strategy. NO 2 -Boron-dipyrrolemethene (BODIPY) was prepared firstly, and then the -NO 2 group was reduced to -NH 2 group. Finally, the NH 2 -BODIPY was introduced to chitosan by Schiff base formation reaction through bi-aldehyde. Eventually, fluorescent chitosan hydrogel was obtained. The as-prepared fluorescent hydrogel probe could detect Hg 2+ /Hg + through PET mechanism with the detection limit of 0.3 μM. The recognition site which combines Hg 2+ /Hg + is C N, it is just formed in the reaction with chitosan and the amino group on BODIPY. Adsorption capacity of the fluorescent hydrogel is 121 mg·g −1 , which is almost seven times of the original chitosan. The isotherm and kinetics of Hg 2+ /Hg + removal follows Langmuir isotherm and pseudo-second order kinetics , respectively. Besides, a series of fluorescent hydrogels were prepared to compare the elasticity, hydropHilicity , fluorescence intensity and adsorption capacity.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2022
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IF 8.025
Lin Yue,Meihong Zheng,Min Wang,Imran Mahmood Khan,Xiaowei Ding,Yin Zhang,Zhouping Wang
The development of new antimicrobial agents is important to combat infections caused by pathogenic bacteria. Herein, Hydroxypropyl chitosan (HPCS), a hydrophilic modified product of chitosan (CS), was employed as a carrier of the photosensitizer chlorin e6 (Ce6) through an amide bond to obtain the products (HPCS-Ce6 conjugates) with a degree of substitution (DS) ranging from 2.95% to 5.25%. The UV–vis absorption spectra and 1 H NMR spectra confirmed the successful synthesis of the products. The products have a better and more stable reactive oxygen species (ROS) generation capacity and higher bacterial affinity than Ce6. At a very low dose (1.8 μg/mL), the highest DS product (HPCS-Ce6-3) can effectively kill Staphylococcus aureus ( S. aureus ) under 660 nm irradiation. In addition, the HPCS-Ce6 conjugates showed high biocompatibility in the CCK-8 test. The HPCS-Ce6 conjugates could be a photodynamic antibacterial agent with good water solubility, high biocompatibility, and antibacterial activity .
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LANGMUIR
·
2022
·
IF 4.331
Shuhong Li,Fan Yang,Kailing Xiang,Jiacheng Chen,Ye Zhang,Jincheng Wang,Jibo Sun,Yuan Li
A multifunctional microspheric soil conditioner based on chitosan-grafted poly(acrylamide-co-acrylic acid)/biochar [CS-g-P(AM-co-AA)/BC] was prepared. First, the P(AM-co-AA) was synthesized and successfully grafted onto CS, and the three-dimensional network structure of microspheres was formed with N,N-methylenebis(acrylamide) as the cross-linking agent according to the inverse suspension polymerization method. Meanwhile, BC and urea were encapsulated into the body of microspheres during the polymerization. The structure of the microspheres was analyzed by Fourier transform infrared spectroscopy, polarized optical microscopy, and scanning electron microscopy, and the mechanism of adsorption of Cu2+ on the microspheres was investigated by X-ray photoelectron spectroscopy. Furthermore, the experimental results demonstrated the excellent water absorption and retention capabilities of microspheres, and the release rate of urea was dramatically reduced. Importantly, the introduction of BC significantly enhanced the adsorption performance of the microspheres with respect to heavy metal ions. Consequently, the multifunctional soil conditioner held promise for use in soil improvement and agricultural production.
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Journal of Nanomaterials
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2022
·
IF 3.791
Xiaohui Peng,Dai Gong
The study aim reports a new umbilical cord wound repair material based on modified chitosan-based nanosilver (CS-HDH/Ag NPs). The repair of umbilical cord wound has always been the focus of neonatal departments. The study method chitosan, which is famous for its “biological glue,” is used as a modifier to compound silver nanoparticles with strong coordination and adsorption capacity of chitosan. It is worth noting that CS-HDH/Ag NPs has a significant inhibitory effect on common bacterial infection and reduces the incidence of umbilical cord wound inflammation. The study problem wound bleeding and stump shedding and other factors make the periumbilical cord vulnerable to bacterial infection. For study results, the porous and lamellar structure endows the repair material with breathable properties and excellent antiadhesion, which greatly reduces the number of dressing changes and effectively protects the skin of newborns. CS-HDH/Ag NPs provides a new model for efficient neonatal health management.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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2022
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IF 5.062
Dickson Pius Wande,Yue Qiu,Shijie Chen,Lan Yao,Yanghui Xu,Jing Yao,Hui Xiong
Oxaliplatin (OXA) and rapamycin (RAPA) combination therapy have shown the advantages of synergistically inhibiting the growth of cancer cells by enhancing apoptosis in cancerous cell lines. However, drug resistance and the lack of an orally administered formulation which exhibited the best clinical dosing compliance limited the clinical application of this regimen. Here, we report a nanogel-polymersomes drug delivery system (i.e.TMOR-CDAN) based on modified chitosan, chitosan diacetate (CDA), methoxy-poly-(ethylene glycol)-b-poly (lactide) (MPP), and D-alpha-tocopheryl polyethylene glycol succinate (TPGS) with permeation-glycoprotein (P-gp) inhibition capability for enhancing the oral chemotherapy efficacy of erroneously soluble RAPA and its synergistic chemotherapy with OXA. Hydrophilic OXA and hydrophobic RAPA were co-loaded using MPP and TPGS-based polymer capsules (i.e. TMOR), which were further coated by chitosan-modified gel to form TMOR-CDAN. The TMOR-CDAN displayed higher stability in both acidic and basic pH than free OXA and RAPA and could withstand the harsh gastric environmental conditions, preventing the burst drugs release while releasing the co-loaded drugs in a sustained and controlled manner. The dual-drug-loaded TMOR-CDAN provides a bifunctional platform for synergistic tumor therapy. Compared with the single drug OXA, RAPA, or the OXA and RAPA mixtures (OR), the TMOR-CDAN showed more outstanding in vitro cytotoxicity and in vivo antitumor chemotherapeutic efficacy, endowing the TMOR-CDAN with a prodigious potential for futuristic cancer chemotherapy .
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Hongli Lyu,Yao Han,Rui Zhang,Yundi Wu,Xilong Wu
Significant amounts of radioactive wastewater including uranium are discharged into the environment as a result of the expansion of large-scale nuclear power. Due to uranium's toxicity and bioaccumulation, it is crucial to develop efficient and long-lasting adsorbents with functional groups for improving the selective removal of U(VI). By successfully introducing amidoxime and phosphate groups into quaternary ammonium chitosan (QCS-AO/P, i.e., QAP), an antimicrobial composite nanofiber adsorbent (PQAP) composed of polyvinyl alcohol (PVA) and the as-prepared QAP was synthesized via the solution blow spinning technology (SBS) technique for the highly efficient recovery of uranium from wastewater. The influence of initial pH, contact time, and sorbent composition on the uranyl ion absorption and the antibacterial assay was studied. The PQAP composite fiber mat had the highest adsorption capacity of uranyl ions at pH 8 (559.26 mg/g), and showed excellent antibacterial activities. After six adsorption–desorption cycles, PQAP still retained a high uranium adsorption capacity of 420 mg/g and elimination efficiency (84%). The novel integrated sorption and antibacterial strategy provides new insights for highly efficient treatment of radioactive wastewater.
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Polymer-Plastics Technology and Materials
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2022
·
IF 2.439
Zicheng Jiang,Su Ma,Gang Zhang,Dongdong Song,Yanlin Wang,Fujing Lao
A chitosan-based flame retardant with a caged structure, chitosan maleic acid mono (1-thio-phosa-4-hydroxymethyl-2,6,7-trioxa-bicyclic [2.2.2] octan-4-methylene) ester salt (CS-MA-SPEPA), was synthesized and characterized. Cone calorimeter (CC) results indicated that the introduction of CS-MA-SPEPA into an unsaturated polyester resin (UPR) matrix could effectively reduce the HRR, TRR, and SPR. More importantly, the incorporation of CS-MA-SPEPA suppressed the release of toxic gases (CO) from the UPR matrix. The char residues results implied that the combination of CS-MA-SPEPA into UPR increased the degree of graphitization of the matrix and made char residues intumescent and tight, which could efficiently block the exchange of oxygen and heat.
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Foods
·
2022
·Vol. 11
·期 18
·2747
·
IF 5.561
Yongshuai Jing,Yameng Zhang,Wenjing Cheng,Mingsong Li,Beibei Hu,Yuguang Zheng,Danshen Zhang,Lanfang Wu
Most proteins given orally have low bioavailability and are easily eliminated by rapid metabolism in vivo. In order to immobilize the drug at the site of administration and delay its release, a natural, gentle release system was designed. In this study, a heteropolysaccharide (ZOP) was isolated fromZingiber officinaleusing an ultrasonic assisted extraction method. ZOP Ara = 1.97: 1.15: 94.33: 1.48: 1.07. The ZOP/Chitosan (CS) composite hydrogel was synthesized using epichlorohydrin (ECH) as a cross-linking agent. The structure, morphology, and water-holding capacity of the composite hydrogel were characterized. The data showed that the addition of ZOP improved the hardness and water-holding capacity of the material. A swelling ratio test showed that the prepared hydrogel was sensitive to pH and ionic strength. In addition, the degradation rate of the hydrogel in a phosphate-buffered saline (PBS) solution with a pH value of 1.2 was higher than that in PBS with pH value of 7.4. Similarly, the release kinetics of Bovine serum albumin (BSA) showed higher release in an acidic system by the hydrogel composed of ZOP/CS. The hydrogel prepared by this study provided a good microenvironment for protein delivery. In summary, this composite polysaccharide hydrogel is a promising protein-drug-delivery material.Keywords:Zingiber offtcinale;polysaccharide;chitosan;hydrogels;drug release;degradation
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Weiguang Zhao,Shiyi Cao,Haoxin Cai,Yang Wu,Qi Pan,Heng Lin,Jun Fang,Yinyan He,Hongbing Deng,Zhihong Liu
Reconstruction of multilayered and functional smooth muscle tissues remains a challenge nowadays. Cryogels possess great advantages in three-dimensional tissue regeneration owing to the interconnected macroporous structure, but their applications have been hindered because of limited mechanical properties. Inspired by the natural extracellular matrix, cellulose acetate electrospun nanofibers (NFs) were incorporated to chitosan/silk fibroin (CS/SF) cryogel scaffolds to address this problem in this work. Compared with pure CS/SF scaffolds, CS/SF/NFs composite scaffolds showed roughened surface and enlarged pore size (216.2 ± 65.3 μm vs. 263.1 ± 75.7 μm) allowing for cell adhesion and proliferation. Incorporation of nanofibers upgraded the mechanical properties of scaffolds with a six-fold increase in compressive modulus. The proliferation and infiltration of smooth muscle cells (SMCs) were remarkably improved with the existence of nanofibers. Besides, SMCs cultured on CS/SF/NFs scaffolds displayed higher expression of contraction-related genes, verifying their potential for smooth muscle tissue engineering.
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