JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2020
·Vol. 31
·期 5
·3890-3898
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IF 2.22
Liang Yue,Liu Lizhu,Zhang Wenlong,Weng Ling,Hu Deshuai,Li Chunyu
Polypropylene (PP) is considered to be a potential eco-friendly cable insulation material. However, space charge accumulation in PP under high electric stress limits its application for HVDC cable. In this paper, PP was modified with 4-acetoxystyrene (AOS) by melt grafting to improve electric properties. The molecular structure of the polypropylene-graft-4-acetoxystyrene (PP-g-AOS) was characterized by means of Fourier Transform Infrared Spectroscopy (FT-IR). The effects of temperature, screw speed, time, initiator content and monomer content on grafting degree of PP-g-AOS were investigated. Furthermore, the influence of grafting degree of PP-g-AOS on space charge suppression, volume resistivity and dc breakdown field strength was investigated. The FT-IR result showed that AOS was successfully grafted onto PP. It was found that under the proper grafting conditions, the obtained PP-g-AOS exhibited a maximum grafting degree of 1.31%. Moreover, PP-g-AOS with grafting degree of 1.14% can suppress space charge efficiently, and increase both volume resistivity and dc breakdown strength. This provides a new idea for the study of polypropylene HVDC cable insulation.
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Nature Communications
·
2020
·Vol. 11
·期 1
·1-10
·
IF 12.121
Sun Tingting,Zhou Beiying,Zheng Qi,Wang Lianjun,Jiang Wan,Snyder Gerald Jeffrey
Assembling thermoelectric modules into fabric to harvest energy from body heat could one day power multitudinous wearable electronics. However, the invalid 2D architecture of fabric limits the application in thermoelectrics. Here, we make the valid thermoelectric fabric woven out of thermoelectric fibers producing an unobtrusive working thermoelectric module. Alternately doped carbon nanotube fibers wrapped with acrylic fibers are woven into π-type thermoelectric modules. Utilizing elasticity originating from interlocked thermoelectric modules, stretchable 3D thermoelectric generators without substrate can be made to enable sufficient alignment with the heat flow direction. The textile generator shows a peak power density of 70 mWm −2 for a temperature difference of 44 K and excellent stretchability (~80% strain) with no output degradation. The compatibility between body movement and sustained power supply is further displayed. The generators described here are true textiles, proving active thermoelectrics can be woven into various fabric architectures for sensing, energy harvesting, or thermal management.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2020
·Vol. 31
·期 5
·3944-3950
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IF 2.22
Tian Xiuna,Dou Hongjian,Wu Lingyuan
Based on the luminescence of Bi 3+ , novel temperature sensing materials CaZrO 3 :Bi 3+ and CaZrO 3 :Bi 3+ /Sm 3+ were successfully synthesized by solid-state reaction. The XRD patterns show that the synthesized materials have a pure phase of CaZrO 3 . The XPS results show that the Bi 3+ and Sm 3+ can be detected in CaZrO 3 :Bi 3+ /Sm 3+ . With the excitation of 318 nm, the CaZrO 3 :Bi 3+ material shows intense temperature-dependent luminescence. The maximum relative sensitivity can be obtained at 440 K (1.78% K −1 ). Under the excitation of 408 nm, the CaZrO 3 :Sm 3+ material shows the characteristic emission peaks of Sm 3+ . The spectral overlap between the emission spectrum of Bi 3+ and the excitation spectrum of Sm 3+ leads to an energy transfer from Bi 3+ to Sm 3+ in CaZrO 3 :Bi 3+ /Sm 3+ phosphor. With the excitation of 318 nm, the emission spectrum of CaZrO 3 :Bi 3+ /Sm 3+ material shows the characteristic peaks of Bi 3+ and Sm 3+ . The fluorescence decay curves also show the evidence of the energy transfer from Bi 3+ to Sm 3+ . The luminescence intensity ratio of Sm 3+ and Bi 3+ in CaZrO 3 :Bi 3+ /Sm 3+ shows obvious temperature dependence. Based on the luminescence intensity ratio, a large relative sensitivity is obtained at 443 K (1.15% K −1 ).
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Journal of Oceanology and Limnology
·
2020
·Vol. 39
·期 1
·160-172
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IF 0.617
Zhou Xudong,Jiang Xincheng,Gao Shan,Wan Zhenjia,Gao Pengcheng
The increasing use of pharmaceuticals has become a major environmental issue in China. The presence of antibiotics in water may have deleterious effects on non-target aquatic organisms such as microalgae. In this study, a cyanobacterium and an alga species in surface waters, Microcystis aeruginosa and Chlamydomonas microsphaera , were exposed to 0, 0.1, 0.5, 1.0, 2.0, 5.0, 10.0, and 20.0 mg/L of oxytetracycline dihydrate (OXY) and sulfamethoxazole (SMZ) for 96 h to determine the effects of these antibiotics on the growth and surface morphology. Moreover, the photosynthetic activity and the contents of superoxide dismutase (SOD), malondialdehyde (MDA), and protein were measured to examine the biochemical characteristics of M. aeruginosa and C. microsphaera under OXY and SMZ stress. The effects of both antibiotics on the growth of both species were concentration-dependent and characterized by low-dose stimulation and high-dose inhibition. C. microsphaera was more sensitive to both antibiotics than M. aeruginosa was. The algal cell membranes of both species disintegrated after exposure to a high concentration of OXY. All of the physiological parameters measured in this study were relatively stable at low concentrations of OXY and SMZ. After exposure to high concentrations of OXY and SMZ, photosynthetic activity decreased significantly, whereas lipid peroxidation and the abundance of SOD, MDA, and protein increased significantly. Thus, low-dose antibiotics may increase algal blooms in eutrophic waters.
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JOURNAL OF MATERIALS SCIENCE
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2020
·Vol. 55
·期 27
·13216-13231
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IF 3.553
Huang Liqu,Wang Xianli,Zhang Yue,Cheng Zhaojun,Xue Feng,Guo Yunfei,Deng Yongji,Chu Chenglin,Tao Li,Bai Jing
Hypospadias is a common congenital malformation of the male urogenital system. As a recently arisen reconstruction method for hypospadias, polymer tissue engineering urethral scaffold often results in necrosis and other complications due to the lack of bioactivity. To improve the bioactivity of polymer, in this work, we prepared biodegradable Mg/poly(lactic-co-glycolic acid) (PLGA) composite nanofiber scaffolds by electrospun with 3, 6, and 9 wt.% of micron-scale Mg particles. The mechanical properties of the PLGA scaffold gradually decrease with the addition of Mg particles but still at an acceptable level. On the other hand, these composite scaffolds show very good biocompatibility and promotional bioactivity, namely non-cytotoxicity, gradual proliferation enhancement, and good adhesion state of human adipose stem cells (HADSCs) on the scaffold surface. Besides, through quantitative real-time polymerase chain reaction (qRT-PCR) test, different genes expression levels of human umbilical vein endothelial cells (HUVECs) were also gradually up-regulated with the increase in Mg content. The present results indicate that Mg containing PLGA scaffolds might not only have the potential to promote tissue regeneration related to urethral repair, but also stimulate endothelial cells to achieve vascularization and anti-inflammatory functions. Consequently, considering both the mechanical properties and bioactivity for clinical demand, the Mg/PLGA composite scaffolds with suitable Mg contents are promising for the regeneration of defective urethral tissues.
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Cancer Cell International
·
2020
·Vol. 20
·期 1
·1-15
·
IF 4.175
Guo Caixia,Shi Hongmei,Shang Yuli,Zhang Yafei,Cui Jiajia,Yu Hongtao
Background LncRNAs are key regulators in cancer. The current study explored the role of lncRNA LINC00261 (LINC00261) in lung cancer (LC). Methods Expression of LINC00261 in LC tissues and cells was determined by quantitative real-time polymerase chain reaction (qRT-PCR). Pearson’s Chi square test and Kaplan–Meier analysis were performed to evaluate the correlations between LINC00261 expression and clinical characteristics, and overall survival time. A549 and SPC-A1 cells were transfected with LINC00261 overexpression plasmid, cell viability, cell number, and apoptosis were detected by CCK-8 assay, colony formation, and flow cytometry. Moreover, wound-healing and transwell assay were performed to detect cell metastasis and invasion. Expressions of proteins related to cell proliferation and metastasis were determined by Western blot. Xenograft was constructed, and tumor size and weight were measured and the effects of LINC00261 overexpression on tumor growth were detected. Bioinformatics analysis, dual-luciferase reporter assay, qRT-PCR, correlation analysis, and functional rescue experiments were conducted on clinical cases and LC cells to explore the molecular mechanism of LINC00261 in LC. Results In LC, LINC00261 expression was down-regulated, and was associated with more advanced TNM stage, metastasis and a shorter survival time. LINC00261 overexpression inhibited the growth and metastasis of LC cells in vitro and tumor growth in vivo. Furthermore, miR-1269a directly interacted with LINC00261 and FOXO1. The expressions of miR-1269a and FOXO1 were dysregulated by LINC00261 in LC. Additionally, miR-1269a promoted the progression of LC through targeting FOXO1. Conclusions Down-regulation of LINC00261 expression has a prognostic value in LC, and overexpression LINC00261 inhibits LC progression via targeting miR-1269a/FOXO1 axis.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 24
·30243-30253
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IF 3.056
Xu Wenqing,Gao Lei,Yang Yang,Zhu Tingyu,Qi Guisheng
The deposition of NH 4 HSO 4 on catalysts is one of the key issues for selective catalytic reduction of NO x . In this study, NH 4 HSO 4 was preloaded on catalysts, and the effects of MoO 3 and CeO 2 doping on the decomposition and reactivity of NH 4 HSO 4 on V 2 O 5 /TiO 2 catalysts are studied. The results show that the introduction of MoO 3 and CeO 2 significantly promoted NO x conversion on the V 2 O 5 /TiO 2 catalysts. Doping with MoO 3 could effectively enhance the S and H 2 O resistance of the catalysts. Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) analysis indicate that it is the strong chemical interactions between NH 4 HSO 4 and the catalysts that are adverse to the decomposition of NH 4 HSO 4 . However, doping with MoO 3 apparently inhibits these interactions, which significantly decrease the decomposition temperature of NH 4 HSO 4 . In situ FTIR experiments show that the NH 4 + in preloaded NH 4 HSO 4 could react with gaseous NO on catalysts, and doping with MoO 3 could facilitate the reaction rate.
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JOURNAL OF FLUORESCENCE
·
2020
·Vol. 30
·期 3
·679-685
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IF 2.093
Chen Xuanming,Hu Na,Wei Huifeng,Wang Haibo
Chirality plays a very important role in medicine, biochemistry and other fields. Because the enantiomers of chiral drugs often show different pharmacology activity, metabolism, and toxicity, therefore, the recognition of chiral molecules is very important, and has become a hot spot and frontier of modern chemical research. In this paper, a new method for recognizing chiral molecular based on naphthalimide dye(NA)⊂cucurbit[5]uril(CB[7]) assembly is developed. NA as guest can be combined with the host CB[7] to form a 1:1 NA⊂CB[7] assembly. Furthermore, this assembly was used as a fluorescent probe to recognize D/L-phenylalanine and D/L-phenylalaninol by fluorescence titration. When D-phenylalanine or D-phenylalaninol was added to NA⊂CB[7] assembly, the fluorescent intensity of assembly was partially quenched, but when L-phenylalanine or L-phenylalaninol was added to NA⊂CB[7], the fluorescence intensity of the assembly almost unchanged. Herein, chiral recognition platform based on achiral NA⊂achiral CB[7] was constructed.
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RARE METALS
·
2020
·Vol. 40
·期 7
·1940-1948
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IF 2.161
Li Jia-Xin,Chen Yu-Hong,Bai Zhang-Jun,Zhao Bao-Jun,Jiang Liang,Wu Lan-Er
Ta–W alloys have unique properties but their applications at high temperatures are restricted due to their poor oxidation resistances. The addition of Al and Ti decreases the oxidation rate of the alloy, as Al-contained protective oxide layer could be formed. In this study, ternary and quaternary Ta–W alloys containing Al and Ti were prepared by hot press sintering. The microstructures and oxidation behaviors of the alloys were studied at 1173 K. The results show that the oxidation kinetics of all alloys follows a parabolic law at short oxidation periods. After cyclic oxidation, the kinetics of quaternary alloys still obeys the parabolic law but that of ternary alloy has been changed into linear law kinetics after 8-h oxidation. For ternary alloy, an outer layer with dense and continuous alumina was formed during the initial stage, and phase transformation caused the oxides to peel off. By comparison, the quaternary alloys depicted continuously solid solution of the oxides layer. Overall, Al and Ti played key roles in oxidation degree and affected the oxidation kinetics of ternary and quaternary alloys.
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Communications Biology
·
2020
·Vol. 3
·期 1
·1-12
·
IF 4.165
Zhou Lulu,Chen Lv,Hu Xiaochun,Lu Yonglin,Liu Wenjie,Sun Yanting,Yao Tianming,Dong Chunyan,Shi Shuo
Despite its great potential in cancer therapy, phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT), often cause metastasis of tumors. Immunotherapy has revolutionized the cancer treatment owing to the capability of activating immune system to eliminate tumors. However, the integration of phototherapy and immunotherapy in a single nanoagent for cancer therapy is still a challenging task. Here, we fabricated (Cu 9 S 5 @mSiO 2 -PpIX@MnO 2 @CpG (CSPM@CpG)) as a synergistic therapeutic model for phototherapy enhanced immunotherapy. The intracellular uptake of cytosine-phosphate-guanine (CpG) promoted the infiltration of cytotoxic T lymphocytes (CTLs) in tumor tissue, further stimulating the production of interferon gamma (IFN-γ) and remarkably elevating the immune response level. Excellent anti-tumor effects have been achieved by synergistic PTT/PDT/immunotherapy. The metastasis of tumors was effectively inhibited by the immune response of CpG. Thus, our proposed work provides a strategy to combine phototherapy with immunotherapy to enhance the therapeutic efficiency and further inhibit metastasis of tumors.
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 7
·1-9
·
IF 6.232
Wang Caixia,Li Mengsi,Wang Peijin,Liu Defang
An electrochemiluminescence (ECL) analytical platform is constructed based on boron nitride quantum dots (BNQDs) as a novel coreactant of luminol for quantitative assay of concanavalin A (Con A). Different from previous research that mainly focuses on its superior optical properties, BNQDs are used for the first time as a coreactant for boosting ECL intensity of luminol, which has a 10-fold enhancement compared with individual poly(luminol/aniline) nanorods loaded on reduced graphene oxide (PLA-rGO) using GCE. On the basis that BNQDs contain an abundance of active amino, a possible mechanism of amino oxidation facilitating ECL emission is proposed. Firstly, luminol as light spices are oxidized to luminol •− and BNQDs generate an abundance of BNQDs-NH +• via electrochemical oxidization, producing reductive intermediates BNQDs-N • in alkaline conditions. Finally, BNQDs-N • react with luminol •− to obtain the excited species AP 2−* , returning to ground state and emitting light. Due to the hindrance effect of Con A, the ECL intensity decreases gradually as various concentrations of Con A are modifying the electrode surface. Therefore, a sensitive ECL biosensor for detecting Con A is constructed exhibiting a wide linear range of 1.0 pg·mL −1 to 1.0 μg·mL −1 and a low detection limit of 0.15 pg·mL −1 .
Schematic representation of an electrochemiluminescence (ECL) biosensor based on boron nitride quantum dots (BNQDs) as an efficient coreactant of reduced graphene oxide functionalized poly(luminol/aniline) (PLA-rGO) for quantitative assay of concanavalin A (Con A).
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 6
·1-10
·
IF 6.232
Liu Xingyu,Li Xiangqian,Dong Pei,Wu Zhiming,Gao Jinwei,Wang Qianming
A low-molecular-weight molecule (4-(2-(3-(dicyanomethyl)-5,5-dimethylcyclohex-1-en-1-yl)vinyl)phenyl-benzoate, DDPB) has been developed. The organic framework possesses very weak fluorescence . The feasibility of the signal transduction has been performed via fluorometric titrations in solution. DDPB gives rise to responses to carboxylesterase 2 (CES2) based on “off-on” responses. The red emission at 670 nm has been derived from the enzyme-induced hydrolysis of ester linkages, thus suppressing the intramolecular charge transfer (ICT) effect and thereby generating the fluorescent segment. The optical excitation window for this probe is extended to the visible light range ( λ ex = 516 nm), and it will induce less harmful influence on biological substances. The detection limit for the measurement of CES2 concentration is as low as 2.33 mU/mL. The conventional studies concerning the activation process are generally performed within only a single liveing cell system. In this study, it is the first time that expression of carboxylesterase 2 in five kinds of cell lines (HeLa > C1498 > active T cell > Jurkat > unactive T cell) has been clarified by flow cytometry, Western blotting, and confocal microscopy analysis. The elucidation of CES2 and its variability in a variety of cells will open new ways for drug metabolism and disease prevention.
We reported a new “substrate-mediated light-on” strategy based on an ester bond cleavage reaction. Most of prepared nanomaterials and organic fluorophores possessed short wavelength emissions in the blue or green region which will not be difficult for cellular imaging. In this study, a novel functional molecule (DDPB) was considered as the substrate for CES2 and the optical “off-on” response was realized. DDPB was cell permeable and possessed very low cytotoxicity. Moreover, the identification of CES2 and their subtle changes in five different cells afforded the sequence for carboxylesterase-2 as Hela > C1498 > Active T cell > Jurkat > Unactive T cell. Inhibition studies showed that the hydrolysis of DDPB was effectively suppressed by bis-p-nitrophenyl phosphate and the cellular tracking results firmly supported this point. To our knowledge, the inter-individual variability for the CES2 expressions in five different cell lines has never been reported via the substrate induced optical changes.
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