RSC Advances
·
2014
·Vol. 4
·期 48
·25106-25113
·
IF 3.708
Rong-li Zhang,Sheng Xu,Jing Luo,Dong-jian Shi,Chen Liu,Xiao-ya Liu
Nanohybrids, comprising gold nanoparticles (Au NPs) and polymer NPs have attracted significant attention in recent years due to their excellent physical and chemical properties. In this work, a novel kind of nanohybrids based on Au NPs and biocompatible poly(γ-glutamic acid)-graft-3,4-dihydroxy-L-phenylalanine (γ-PGA-g-DA) NPs was conveniently achieved through a green and facile one-pot strategy. By simply adding HAuCl4·3H2O to the aqueous solution of γ-PGA-g-DA copolymer, the decrease of the pH value induced the self-assembly of γ-PGA-g-DA into NPs, during which Au3+ was adsorbed in the in situ formed NPs and spontaneously reduced to Au NPs by the dopamine moieties of γ-PGA-g-DA, leading to the formation of Au@γ-PGA-g-DA nanohybrids. In the reaction process, γ-PGA-g-DA was used as scaffold and reductant simultaneously, avoiding the use of extra toxic reducing reagents. Interestingly, the particle size and clustering of Au NPs in Au@γ-PGA-g-DA nanohybrids were varied with the loadings of HAuCl4·3H2O. This one-pot preparation process is very simple, fast, and completely based on the principles of green chemistry. Furthermore, the resultant biocompatible Au@γ-PGA-g-DA nanohybrids were used to detect L-tryptophan and exhibited a good analytical performance. The novel Au@γ-PGA-g-DA nanohybrids are a promising system for detecting the amino acids and biological species.
研究领域:
材料科学
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生物医学
·
化学工程
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产品关联
DOI
高影响因子
Biomaterials Research
·
2024
·
IF 8.1
Xiuyun Li,Wenli Han,Yilin Zhang,Dongmei Tan,Min Cui,Shige Wang,Wenna Shi
Current hemostatic materials have many shortcomings, such as biotoxicity or poor degradability, and do not effectively promote wound healing after hemostasis. To address these limitations, a hemostasis-promoting wound-healing hydrogel, polyglutamic acid/polyethyleneimine/montmorillonite (PPM), comprising polyglutamic acid, 3,4-dihydroxybenzaldehyde-modified polyethyleneimine, and amino-modified montmorillonite (montmorillonite-NH2) was constructed in this study. Due to the excellent water absorption abilities of γ-polyglutamic acid, the PPM and polyglutamic acid/polyethyleneimine hydrogels could rapidly absorb the blood and tissue fluid exuded from the wound to keep the wound clean and accelerate the blood coagulation. The homogeneous distribution of montmorillonite-NH2 enhanced not only the mechanical properties of the hydrogel but also its hemostatic properties. In addition, the modification of polyethylenimine with 3,4-dihydroxybenzaldehyde provided anti-inflammatory effects and endorsed the wound healing. Cellular and blood safety experiments demonstrated the biocompatibility of the PPM hydrogel, and animal studies demonstrated that the PPM hydrogel effectively stopped bleeding and promoted wound healing. The concept design of clay-based hydrogel may create diverse opportunities for constructing hemostasis and wound-healing dressings.
研究领域:
生物材料
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伤口愈合
·
止血
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2021
·Vol. 168
·期 5
·057511
·
IF 4.316
Xin-Qin Cai,Kai Zhu,Bo-Tao Liu,Qing-Yu Zhang,Yu-Hui Luo,Dong-En Zhang
In this work, γ-Fe2O3/CNTs composite was facile synthesized by simple hydrothermal method and hydrazine hydrate treatment at low temperature (CNTs = carbon nanotubes). The result of VSM shows that the saturation magnetization of Fe2O3/CNTs composites increase from 0 to 1.29 emu g−1 after hydrazine hydrate treatment, indicating that the Fe2O3 in the composite transforms from α phase to γ phase. Moreover, the electrochemical properties of both α-Fe2O3/CNTs and γ-Fe2O3/CNTs was studied. Compared with α-Fe2O3/CNTs, γ-Fe2O3/CNTs shows enhanced electrochemical performance toward paracetamol determination. Under optimum condition, the γ-Fe2O3/CNTs modified electrode exhibits two linear ranges of 2.5 μM−385 μM and 593 μM−1550 μM and a low detection limit of 0.046 μM. In addition, the constructed sensor can be successfully utilized for detecting paracetamol in different water bodies. This work provides a new clue for the design and construction of excellent electrochemical sensor for paracetamol determination.
研究领域:
材料科学
·
分析化学
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DOI
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 56
·35415-35424
·
IF 3.361
Mingrui Li,Yixuan Liu,Xialing Lin,Jinyu Tan,Song Yang,Hu Li
γ-Valerolactone (GVL) is an attractive biomass-derived platform molecule that plays an important role in the production of biofuels and biopolymers. The synthesis of GVL from renewable biomass and its derivatives has great application prospects but also presents challenges due to the multiple conversion steps involved. Here, a HfCl4-mediated acid–base bifunctional catalytic system was developed, which was demonstrated to be efficient for upgrading furfural (FF) to GVL in a single pot with unprecedented performance. The Lewis acidity of Hf4+ and moderate basicity of HfO(OH)2·xH2O, and strong Brønsted acidity of HCl in situ generated from HfCl4 hydrolysis were found to play a synergistic role in the cascade reaction processes, mainly contributing to the pronounced catalytic activity. The effects of the key reaction parameters, such as the catalyst dosage, reaction time, and temperature, on GVL production were optimized by response surface methodology. It is worth mentioning that the recovered catalyst after thermal treatment could be directly used for the hydrogen transfer processes, like FF-to-furfuryl alcohol conversion. This catalytic strategy opens a new avenue for the selective conversion of biomass feedstocks involving multiple steps and complex processes.
研究领域:
化学工程
·
可再生资源与环境科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Tianyuan Xiao,Jiahui Song,Wenchao Jia,Yanning Sun,Yanzhu Guo,Pedram Fatehi,Haiqiang Shi
The chemical bond cleavage of lignin is a research focus for achieving depolymerized lignin for such applications as adhesives, fuels, fertilizers, etc. The depolymerization of an industrially available sustainable material, i.e., industrial alkali lignin, in LiBr·3H 2 O/HBr-γ-valerolactone (GVL) was systematically investigated in this study. It was observed that using 3/1 mL/g of HBr/lignin and 8/1 mL/g of GVL/lignin at 110 °C for 90 min, i.e., optimized conditions, resulted in lignin derivatives with an M w of 1889 g/mol and M n of 895 g/mol. The characteristics of the products were studied using FTIR, NMR, SEM, and DLS techniques. The results confirmed that the Hibbert-ketone end group was formed, while the structure of the aromatic ring was not changed on the depolymerized lignin. After the depolymerization process, the hydroxyl content in lignin increased from 1.91 mmol/g to 2.96 mmol/g. The product derived from the LiBr·3H 2 O/HBr-GVL depolymerization system displayed a spherical particle morphology. The addition of GVL to lignin depolymerization processes improved the bonding between lignin and inorganic molten salts, thereby promoting the acid-catalyzed cleavage of aryl ether bonds in lignin. Current research supports the conclusion that LiBr·3H 2 O/HBr-GVL lignin depolymerization is a sustainable and effective chemical pathway for generating depolymerized lignin.
研究领域:
化学工程
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材料科学
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产品关联
DOI
PubMed
高影响因子
CATALYSIS TODAY
·
2024
·
IF 5.2
Xin Xu,Bolin Xia,Amirreza Gholivand,Xiaoyu Zhang,Yunpeng Zhang,Linhui Liu,Daiqi Ye,Peirong Chen
Selective dissolution is highly promising for tailoring the structures and functions of metal oxides toward various applications. Here, we demonstrate a successful fabrication of porous γ-MnO 2 by selectively dissolving Ca in a CaMnO 3 perovskite (CMO) via dilute HNO 3 treatment. The perovskite-derived γ-MnO 2 (denoted as CMO-72 h) outperformed drastically the pristine CaMnO 3 and a commercial γ-MnO 2 in the catalytic oxidation of NH 3 and NO, two representative gaseous pollutants in the atmosphere. Physicochemical characterization by X-ray photoelectron spectroscopy and temperature-programmed techniques (including H 2 -TPR, O 2 -TPD and NH 3 -TPD) suggests that the excellent catalytic performance of CMO-72 h is associated with its low–temperature reducibility and abundant surface–active oxygen species. Specifically, acid treatment led to the oxidation of Mn 3+ to Mn 4+ on the surface, increasing significantly the Mn 4+ /Mn 3+ ratio from 0.76 (for CMO) to 1.45 (for CMO-72 h) and, meanwhile, generating additional surface oxygen vacancies . As a result, O 2 molecules can be easily adsorbed and activated on the CMO-72 h, leading to improved performance in NH 3 and NO oxidation. This study may offer new opportunities in the synthesis of high-performance Mn oxide catalysts for environmental applications.
研究领域:
环境科学
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材料科学
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催化化学
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产品关联
DOI
高影响因子
RSC Advances
·
2014
·Vol. 4
·期 93
·51184-51193
·
IF 3.708
Qing Zhang,Tao Wu,Peng Zhang,Ruijuan Qi,Rong Huang,Xuefeng Song,Lian Gao
Hydrogen reduction of hierarchical spinel intermediates that were synthesized by a facile hydrothermal method results in Ni/γ-Al2O3 nanocomposites with Ni nanoparticles (∼5.5 nm) well dispersed and embedded in nanoflakes of the hollow Al2O3 microspheres. The good dispersion of small metal nanoparticles and strong metal–support interactions that resulted from decomposition of spinel intermediates during reduction are essential for the efficient and sustainable high temperature dry reforming of methane (DRM) catalysis. The high surface area (170 m2 g−1) composite catalysts show coke and sintering resistance in long term DRM catalysis at 750 °C, the highest temperature ever tested for hierarchical nanostructures. Ni loadings and the calcination temperatures of the spinel intermediate are investigated for their effect on the morphology and the catalytic performance of the final catalysts. It is interesting that some initially non-active control catalysts can be activated during long term testing.
研究领域:
化学工程
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催化科学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2018
·
IF 3.141
Yanchun Wan,Huilin Yi,Yujun Wang,Guangsheng Luo
A novel and effective method is proposed to prepare uniform γ-alumina microspheres with large pore volumes using a coaxial microchannel. In this process, the so-called “temperature/pH-induced gelation” method, in which methylcellulose (MC) and hexamethylenetetramine (HMTA) are added to accelerate gelation of Al(OH)3 sol, is combined with microfluidics technology to ensure sphericity and dimensional homogeneity of the prepared microspheres. The influences of the sol concentration, the properties of pseudoboehmite (PB) used to obtain the sol, and the two-phase flow rates were investigated. By controlling the sol concentration at 10 wt % and the continuous to dispersed phase flow ratio at 14–50, 750–380-μm-diameter γ-alumina microspheres with uniform pore structures were synthesized using an Al(OH)3 sol obtained from PB3. The pore volume was 1.20 mL/g, and the crushing strengths were 8.19–16.67 N/mm2. Prepared at the maximum two-phase flow ratio, sample S9 exhibited the most uniform particle size of about 380 μm.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
Catalysis Science & Technology
·
2019
·Vol. 10
·期 2
·440-449
·
IF 5.726
Pengqi Zhu,Jin Zhang,Jie Wang,Peng Kong,Yunwei Wang,Zhanfeng Zheng
Hydroxyl coordinated ruthenium dispersed on the surface of γ-Al2O3 can be applied to the selective oxidation of amines with light irradiation and an atmospheric pressure of O2 at room temperature. Sunlight is also an effective light source for the selective aerobic oxidation of primary amines to corresponding nitriles. The high photocatalytic activity and selectivity over Ru/γ-Al2O3 originate from the adsorption of amines and imine intermediates on the abundant surface OH groups of the photocatalyst and further formation of Ru–amide species by ligand exchange of adsorbed amines and imine intermediates with adjacent exposed active Ru sites. Light is introduced to the system successfully via the formation of Ru–amide species, which are used as the light absorption sites of the photocatalytic selective oxidation of amines. Primary amines are directly converted to corresponding nitriles via a two-step oxidative dehydrogenation process.
研究领域:
化学工程
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材料科学
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环境科学
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产品关联
DOI
高影响因子
Chemistry-An Asian Journal
·
2025
·
IF 3.3
Xiaoqing Jia,Yingfeng Wei,Xinyuan Zhang,Qiuping Gu,Youshun Liu,Shige Wang,Chunping Zhu
A dual-drug-loaded γ-polyglutamic acid (γ-PGA) hydrogel was synthesized, integrating third-generation dendrimers (G3) as cross-linkers for the simultaneous encapsulation of hydrophilic doxorubicin (DOX) and hydrophobic camptothecin (CPT). This hydrogel, formed via an efficient EDC/NHS-mediated reaction, demonstrated a biocompatible, porous, and pH-responsive network. The hydrophobic core of G3 significantly enhanced CPT loading, while γ-PGA facilitated effective DOX incorporation. Controlled drug release was observed, with DOX releasing faster in acidic tumor-like environments, optimizing therapeutic impact at the tumor site. In vitro studies highlighted the hydrogel's high biocompatibility and synergistic anticancer efficacy, reducing CT26 colon cancer cell viability more effectively than single-drug systems. In vivo experiments confirmed substantial tumor suppression, prolonged survival, and the absence of systemic toxicity in murine models. These results underscore the potential of this dual-drug delivery platform as a robust, multifunctional system for cancer therapy. The biocompatibility, degradability, and tailored drug release characteristics make this hydrogel a promising candidate for clinical translation, offering a novel solution for enhancing cancer treatment efficacy while minimizing side effects.
研究领域:
生物材料
·
药物递送
·
肿瘤学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Fuxin Liang,Yulin Wei,Yuhang Du,Fan Yang,Zhe Pang,Junyan Wu,Sai Huang,Honglei Wang,Qinggang Li,Chao Wu,Guopu Shi
This study investigated the catalytic hydrogenation of ethyl nicotinate using Pd/Al 2 O 3 -SiO 2 foam ceramic catalysts prepared via sol-gel impregnation (SI), sol-gel precipitation (SP), precipitation-impregnation (PI), and co-precipitation (CP). We aimed to evaluate the performance and stability of these catalysts as coatings on foam ceramic surfaces in a high-pressure hydrogen reactor at 403 K and 5 MPa. Various physicochemical characterization methods were employed to correlate catalytic performance with physicochemical properties. Results indicated that sol-gel prepared supports had higher specific surface areas, more acidic sites, and better metal-carrier interactions compared to the precipitation method. SEM analyses revealed flatter and smoother coatings from the sol-gel method, while TEM showed uniform Pd distribution with impregnation. Ultimately, the SI method provided the best catalytic performance with a conversion of 86.77 %. The conversion of the substrate remained above 80 % after five cycles.
研究领域:
化学工程
·
催化材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Xiao Chen,Nannan Zhang,Huaming Wang,Ying Zhong,Tianming Lv,Changhai Liang
The continuous flow selective hydrogenation of maleic anhydride (MA) to γ-butyrolactone (GBL) over highly efficient and long-term stable catalysts is a considerable promising strategy for both lab-scale as well as industrial application. In this work, a PtPdCoNiCu/TiO 2 high-entropy alloy (HEA) catalyst is developed by the colloidal impregnation method, in which the HEA colloids are synthesized by lithium naphthalenide-driven reduction at mild conditions according to the redox potential of the various metals. The PtPdCoNiCu/TiO 2 catalyst exhibits highly efficient in the hydrogenation of MA with 91 % selectivity to GBL at full conversion of MA under the weighted hourly space velocity of 1.14 h −1 , 3 MPa H 2 , and 260 °C. Due to the present of oxygen vacancy in the TiO 2 support and the hydrogen spillover, the PtPdCoNiCu/TiO 2 HEA catalyst presents a low apparent activation energy (75 kJ mol −1 ), boosting the hydrogenolysis of C=O bonds for generating of GBL. The cocktail effect is presented in the PtPdCoNiCu/TiO 2 catalyst, and its catalytic activity is much better than that of corresponding monometallic and bimetallic catalysts. It realizes the reduction and substitution of precious metal catalysts. In addition, the PtPdCoNiCu/TiO 2 catalyst with sintering resistance and acid resistance shows excellent long-term stability within 132 h. This work is of great significance for understanding HEA catalysis at the atomic level and provides the possibility for developing low-cost and efficient precious metal industrial catalysts.
研究领域:
催化化学
·
材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）