FOOD RESEARCH INTERNATIONAL
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2026
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IF 8
Jiatong Jin,Yuqing Dai,Zhangpeng Han,Yunru Cao,Wen Zhao,Liangfu Zhou,Yasai Sun,Qian Zhou
Insoluble dietary fiber from Chinese cabbage outer leaves (CIF) is abundant in bound polyphenols (BPs), while the release of BPs and their influence on the function of CIF remain unclear. This study compared the changes in CIF before and after the removal of BPs and characterized the BPs profiles during gastrointestinal and colonic fermentation. CIF exhibited a markedly denser microstructure with fewer pores and markedly higher antioxidant and α-glucosidase inhibitory activities than BPs-removed CIF (BPR-CIF). UHPLC-OE-MS analysis identified 342 phenolic compounds in CIF, predominantly flavonoids, phenolic acids, and coumarins. The release of BPs during in vitro gastrointestinal digestion was 2.59% (mainly flavonoids, coumarins, and lignans) with kaempferol 3-sophoroside-7-glucoside as the representative compound, and 37.25% (mainly phenolic acids, phenylpropanoids, and stilbenoids) with salicylic acid, mandelic acid, and trans-cinnamic acid as the representative compounds during colonic fermentation, which was more effectively released. The phase dependence of the BPs was further confirmed using quantitative HPLC analysis. Microbiomic data revealed that CIF-BPs reduced the Firmicutes / Bacteroidota ratio and enriched beneficial microbiota (e.g., Bifidobacterium , Lachnoclostridium, and Blautia ) while inhibiting pro-inflammatory microbiota (e.g., Bilophila , Eggerthella, and Fusobacterium ). And the decrease in pH and increase in short-chain fatty acid concentrations further demonstrated these prebiotic effects. Furthermore, the observed microbial changes showed a strong correlation with elevated levels of specific phenolic compounds. These findings enhance our understanding of the interactions between BPs and CIF as natural complexes and provide valuable insights into the high-value utilization of outer leaf waste of Chinese cabbage.
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Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·142
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IF 36.3
Fan Binbin,Yu Jianyong,Wang Xueli,Si Yang,Tang Peixin
Covalent organic framework nanofibers (CNFs) with biomimetic scale-like architecture, record-high aspect ratio ( L / D = 103.05), and superior flexibility were directly synthesized via defect engineering.
Self-standing membranes and nanofibrous aerogels (CNF-As) with designable micro-topological structures were fabricated with 100% CNFs.
CNF-As perform photo-induced uranium extraction with an adsorption capacity and adsorption rate of 920.12 mg g −1 and 89.9%, respectively.
CNF-As exhibit superior underwater stability (> 180 days) and superelasticity (~ 0% deformation after 500 compression cycles), making them promising for practical application in marine systems.
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BIOMARKERS
·
2026
·
IF 1.9
Yang Jiang,Xiaosheng Jin
Background PM2.5-induced COPD lacks effective therapies due to unclear pathogenesis. This study explores the role of miR-122 and PTEN in PM2.5-related COPD.Methods Using a combination of in vitro and in vivo assays, including cigarette smoke extract (CSE)-induced NR8383 cells and a rat smoke model, combined with MTT, qPCR, flow cytometry, WB, HE staining, Masson staining, HIC, and TUNEL assays, we investigated the role of microRNA-122 (miR-122) and phosphatase and tensin homolog (PTEN) in the molecular mechanisms underlying PM2.5-induced COPD.Results Our findings demonstrate that CSE-induced the down-regulated expression of miR-122 leads to the activation of PTEN, which in turn regulates the AKT signaling pathway in NR8383 cells. This modulation results in decreased expression of B-cell lymphoma 2 (BCL2), promoting cell apoptosis. Besides, the result from a rat model of COPD exposed to smoke also confirms this molecular axis which ultimately exacerbating COPD. Specifically, compared with the control, there is significant pulmonary structural damage in model rats exposed to PM2.5, including enlarged alveolar intervals, increased alveolar cavity size, pulmonary fibrosis, and evidence of alveolar destruction with concomitant parabronchial inflammation.Conclusion Our research reveals novel insights of PM2.5-induced COPD and proposes the miR-122/PTEN pathway as a potential therapeutic target.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
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IF 8.5
Bo Yang,Hui Pan,Rui Ke,Haoyuan Li,Kai Liu,Jiahao Wang,Changyu Qu,Chao Ling,Yuan Huang
The oil pollution in aquatic ecosystems poses a serious threat to public health and ecological balance. In addressing this challenge, this investigation employed bacterial cellulose (BC) as the matrix material, through strategic incorporation of chemical cross-linking agents (Butane tetracarboxylic acid and graphene oxide) combined with freeze-drying technology and chemical vapor deposition (CVD) method to fabricate cross-linked BC (CBC) aerogels. Subsequent hydrophobic modification via chemical vapor deposition was implemented to optimize surface properties. Key findings revealed that the cross-linked composite aerogel demonstrated a homogeneous 3D lamellar architecture with negligible crystal precipitation, manifesting remarkable structural stability (linear shrinkage rate 5.88%) and ultrahigh porosity (99.9%) accompanied by minimal average pore diameter (1.9 nm). Enhanced thermal stability was evidenced by increased mass residual rate from 15.9% to 41.5% at 600 °C. The material maintained superior compression resilience through 10 compression cycles at 50% strain, preserving structural integrity in aqueous environments. Optimal hydrophobicity (contact angle 152°) was achieved after 3.5 h of vapor deposition, while remarkable adsorption capacities for various oils were recorded (45–204 g/g). Notably, the composite exhibited outstanding reusability, retaining 85.2% of ethanol adsorption capacity after 20 extraction cycles, and preserving 76.7% of paraffin oil adsorption capacity. These results collectively demonstrate the broad application prospects of this bio-based oil-absorbing material in oil-water separation technologies.
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Advanced Sensor and Energy Materials
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2026
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IF 10.2
Haofan Liu,Yiting Huang,Jianxin Shi,Ya Ren,Xia Luo,Mariya Edeleva,Tong Qi,Liming He,Li Zhang,Yinchu Dong,Xide Dai,Ludwig Cardon,Xiaohong Li,Maling Gou
The integration of biotechnology and information technology has created a growing demand for high-performance flexible bio-electrodes. However, existing conductive polymer systems often struggle to simultaneously achieve high electrical conductivity, excellent stretchability, and high-resolution circuitry that are essential for soft bioelectronics. To address these challenges, we developed a light-curable, elastomeric bio-electrode consisting of a dual-network conductive hydrogel system combining PEDOT:PSS with a photo-crosslinkable Pluronic hydrogel. Utilizing digital light processing (DLP)-based 3D printing technology, this bio-electrode can be rapidly prototyped with customized, high-resolution electrode structures and tailored packaging. Subsequent acid treatment induces molecular chain rearrangement within the electrode, resulting in a denser network topology and significantly enhanced electrical conductivity. Consequently, these flexible electrodes exhibit excellent electrical performance exceeding 300 S/m, while maintaining remarkable flexibility and stretchability. The fabricated electrodes demonstrate good biocompatibility and are capable of delivering electrical stimulation to biological tissues or recording cortical neural signals. This approach provides an efficient strategy for customizing high-performance flexible bio-electrodes, holding significant promise for future medical applications.
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CHINESE JOURNAL OF CATALYSIS
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2026
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IF 17.7
Juxia Xiong,Hao Ma,Yingjun Dong,Benjamin Liu,Xiangji Zhou,Linbo Li,Yuanmiao Sun,Xiaolong Zhang,Hui-Ming Cheng
Bi-based catalysts are known to promote the electrochemical reduction of CO 2 to formic acid (HCOOH) or formate (HCOO − ). However, their implementation presents challenges: the first H + /e − pair transfer to form the key *OCHO intermediate on a Bi surface is a slow, kinetically sluggish endergonic process, resulting in a large overpotential and narrow potential window for high HCOOH/HCOO − selectivity. Altering the localized p -orbital electron states of Bi to change intermediate binding behaviors is difficult. We addressed this problem by using an in-situ polymerization method to obtain a polyaniline-Bi hybrid (PANI-Bi) with Bi surrounded by PANI chains. Combined experimental and computational studies indicate that the polyaniline acted as an “electron pump” that facilitated charge transfer from the PANI backbone to the Bi surface and changed the p -orbital electrons of the Bi active sites. This lowered the energy barrier for the adsorption of intermediates and facilitated *OCHO formation. Consequently, a significant increase in formate production was observed, achieving a single-pass carbon efficiency exceeding 48.7% at 800 mA cm −2 . This organic functionalization strategy, aimed at modifying the electronic structure of heterogeneous catalysts, offers a promising approach for achieving highly selective electroreduction of CO 2 at a high current density.
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Foods
·
2026
·Vol. 15
·期 1
·146
·
IF 5.1
Mengke Zheng,Yan Chen,Peiwen Yang,Yinan Yang,Guihong Qi,Peng Li,Wuduo Zhao,Shihao Sun,Donghao Zhang
Sesame oil is one of the most popular sesame products for consumers. Roasting is a commonly employed heat treatment method in sesame oil processing. This work aims to investigate the effects of roasting temperature and time on sensory profiles, volatile components, fatty acid composition, and oxidative stability of the oil. Quantitative descriptive sensory analysis was employed to reveal changes in aroma characteristics of sesame oils from different roasting conditions. Volatile compounds of the oils were analyzed via headspace solid-phase microextraction/gas chromatography–mass spectrometry (HS-SPME/GC-MS), identifying 56 components, including 30 key aroma-active compounds (odor activity value, OAV ≥ 1) across 18 samples. Principal component analysis (PCA) was performed to explore the effect of roasting conditions on volatiles of sesame oils. The oxidative stability of the oils was also determined by RapidOxy reactor. The results demonstrated that the effect of roasting time on the flavor of sesame oil was greater than that of temperature. Moreover, the effect of roasting conditions (temperature/time) on the fatty acid profile of sesame oil was not significant. This provided some theoretical foundation and data support for improving the processing technology of sesame oil and controlling its flavor quality.
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Scientific Reports
·
2026
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IF 3.9
Wang Aqin,Zhou Zhengbing,Hang Zhou,Lyu Zhengbing,Yang Jingchun,Zhang Lu,Wang Meng,Liu Wei,Zou Liqiang,Yu Jun
Direct oral intervention of spleen aminopeptide (SA) would be limited because of its varied swelling and release rate in different pH environments of digestive fluids. Herein, pH-responsive hydrogel microspheres (3.67 ± 0.04 mm) with positive SA-loaded chitosan (Cs) core and negative alginate (ALG) shell were prepared. Entrapment efficiency was 76.22% and loading rate of SA was 35.17%. Besides the hydrogen bonding, a strong core/shell structure was constructed by forming imine bond via the Schiff base reaction of amino group in Cs with ketone group on SA. In vitro simulated digestion showed that the swelling rate of microspheres was 192.8% (pH 1.2), 2481.5% (pH 6.8), and 1144.3% (pH 7.4). The release rate of SA was 0.9% in simulated gastric fluid for 2 h, 6.0% in simulated intestinal fluid for 2 h and continuous release in simulated colonic fluid for 24 h with a cumulative release rate of 92.4%. After treatment, the observation group exhibited increasing levels of CD3 + , CD4 + , CD4 + /CD8 + , IgA, IgG and IgM. Total effective rate in observation group was 96.15%, being higher than that in control group (84.31%). This work provided a valuable reference for preparing drug-loaded hydrogels to improve the recurrent respiratory infection in children.
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ANALYTICAL CHEMISTRY
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2026
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IF 6.7
Fengli Chai,Dou Wang,Fenggang Li,Saijie Wang,Yao Chen,Yongzhi Huang,Jiuxin Qu,Shuailong Zhang,Jiangjiang Zhang,Xingyu Jiang
Lateral flow immunoassay (LFIA) is a vital point-of-care testing (POCT) technique that is widely used for on-site detection and in vitro diagnosis. Many diseases, particularly cardiovascular diseases (CVDs), require the quantitative detection of multiple biomarkers across a broad dynamic range. Recurrent viral infections like COVID-19 elevate CVDs risk, necessitating early warning and prognostic monitoring, especially based on POCT of multiple blood biomarkers of D-dimer, NT-proBNP, and cTnI across a broad range from pg/mL to μg/mL. Traditional LFIAs lack ultrasensitivity and broad-range quantification. We design the surface chemistry-mediated template-free assembly of metal-aggregation-induced emission luminogens (AIEgen) framework@gold nanoparticles (MAF@AuNPs) for developing ultrasensitive and dynamic dual-quantitative LFIA (ddLFIA). The template-free self-assembled MAF@AuNPs have strong fluorescent and plasmonic properties, avoiding complicated synthesis, chemical modifications, and covalent conjugations, thus leading to highly convenient and versatile visual POCT. MAF@AuNPs ddLFIA achieves a normal detection at ng/mL using chromogenic AuNPs and ultrasensitive detection at pg/mL using fluorogenic MAFs, for which the fluorescence signal is 102–103 times more sensitive than the color signal. MAFs and AuNPs are functionally complementary to form a dynamic, broad-range quantification system covering over 5 orders of magnitude, at the same time having a naked eye sensitivity near 1 pg/mL. The visual POCT using MAF@AuNPs ddLFIA aligns well with clinical chemiluminescent assays. MAF@AuNPs ddLFIA perfectly matches ultrasensitive and broad-range multiple biomarker detections for clinical CVDs diagnosis.
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ACS Applied Materials & Interfaces
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2026
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IF 8.2
Yechen Wang,Hao Yu,Sufang Guo,Qi An
In this work, PVDF-HFP-based piezoelectric composite films incorporating MgO and rGO nanofillers were fabricated via a facile phase-separation method. The influences of filler composition and loading amount on their piezocatalytic and antibacterial performances were systematically investigated. MgO@rGO/PVDF-HFP film (4 wt % of MgO and 4 wt % of rGO) exhibited the best piezocatalytic activity, achieving rapid degradation on RhB, MO, and MB dyes with high efficiencies of 95.88%, 91.42%, and 98.15%, respectively. The dyes were not only decolorized but also further mineralized into inorganic carbon. The composite film also demonstrated excellent antibacterial performance, reaching 100% inhibition against E. coli and S. aureus upon ultrasonication. The superior catalytic behavior is attributed to the formation of the MgO@rGO heterojunction, which optimizes the energy band for the redox reaction, thereby promoting the generation of reactive oxygen species (ROS). Under ultrasonic excitation, the MgO@rGO/PVDF-HFP film produced substantially higher ·O2–, ·OH, and H2O2 levels than the other films, and ROS-trapping experiments confirmed ·OH and electrons as the primary active species. These enhancements arise from efficient charge transfer across the MgO@rGO interface and chemically induced polarization within the PVDF-HFP matrix, which together strengthen the piezoelectric response. This study demonstrates that constructing heterojunction nanofillers in flexible polymers is an effective strategy to enhance piezocatalysis for environmental purification and antimicrobial applications.
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Science China-Materials
·
2026
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IF 7.4
Li Qing,Tang Jiayuan,Yang Yuhan,Chai Jun,Zhang Xiao,Shao Mingfei,Shen Hangjia
Pore-tuning engineering has been proven as an effective strategy in catalyst design for energy storage and conversion. Herein, we propose a rhombic dodecahedral iron and nitrogen co-doped carbon-based material (Fe-N-C) with hierarchical micro-mesoporous structures using mesoporous silica as the pore template and iron launch vehicle. The as-prepared catalysts (m-Fe/NC) exhibit much boosted ORR activity with half-wave potential of 0.81 V and 0.88 V in acidic and alkaline media, respectively. Furthermore, a superior specific capacity of 815 mAh g Zn −1 and stable cell voltage of 1.31 V is achieved at current density of 10 mA cm −2 when using m-Fe/NC as cathode for zinc-air batteries (ZAB). Advanced characterization techniques and theoretical calculations reveal that the introduction of mesopore structure not only improves the active site exposure, but also the proper curvature-induced strain effect from mesoporous concave surface enhances the intrinsic activity. This work provides significant insights for future development of innovative nanoporous electrocatalysts.
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JOURNAL OF FOOD SCIENCE
·
2026
·Vol. 91
·期 1
·e70824
·
IF 3.4
Shun Gao,Feng Ao,Xuyan Zong,Li Li,Li Yang,Ran Qiu,Yiwen Liu,Yi Wang,Li Xuan,Chunli Liu,Qin Wei
Osmanthus fragrans has a pleasant aroma, and different varieties have different aromas and colors. This study systematically assessed how the inclusion of various Osmanthus fragrans cultivars influences critical beer attributes, including physicochemical parameters, sensory characteristics, antioxidant capacity, and volatile flavor profiles. The findings demonstrated that osmanthus addition markedly decreased beer turbidity ( p < 0.05) and enhanced the TPC by as much as 30%. The content of monophenols in beer also increased significantly, especially catechins and gallic acid, which increased by an average of 25 and seven times ( p < 0.05), respectively. Vanillic acid was established as a key determinant of the DSA in osmanthus beer through correlation and cluster analysis ( r = 0.9, p < 0.01). GC–MS analysis identified 50 volatile compounds, with increase in dihydro-β-ionone and irisine content in the osmanthus beer, and sensory evaluation confirmed that the mix and aurantiacus varieties achieved the highest overall acceptability, demonstrating the effectiveness of osmanthus in enhancing the beer's overall flavor and functional properties.
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危险品化学品经营许可证（带存储）