JOURNAL OF HAZARDOUS MATERIALS
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2021
·
IF 10.588
Qinyue Wu,Yan Zhang,Min-hua Cui,He Liu,Hongbo Liu,Zhiyong Zheng,Wei Zheng,Cuicui Zhang,Donghui Wen
This study explored the impact of pyrolysis parameters and modification methods on the characteristics of pharmaceutical sludge biochar, and investigated its capacity and mechanisms for levofloxacin (LEV), a typical fluoroquinolone antibiotics, adsorption. The results showed that S BET of the biochar was improved with temperature increase, but decreased when temperature reached 900 °C. Under the optimal pyrolysis condition of 800 °C and 90 min, the biochar possessed the highest S BET of 264.05 m 2 g −1 , excellent iodine value of 401.41 ± 3.84 mg∙g −1 and phenol adsorption of 57.36 ± 3.39 mg∙g −1 . Among KOH, ZnCl 2 , and CO 2 modifications, ZnCl 2 modification achieved the highest phenol adsorption of 123.40 ± 4.65 mg g −1 , with a significantly improved S BET of 534.91 m 2 g −1 . The maximum LEV adsorption capacity of ZnCl 2 modified biochar, PZBC800, reached 159.26 mg g −1 , which overwhelmed the reported sludge biochars. BET, zeta potential , FT-IR, XPS, and Raman analysis, along with quantum chemistry calculation, revealed that pore filling, hydrogen bonding, π-π interaction, surface complexation, and electrostatic interaction were the main mechanisms for the excellent LEV adsorption performance of PZBC800. Deep removal (99.9%) of Fluoroquinolones (FQs) from pharmaceutical wastewater was also achieved by PZBC800 adsorption. The study promoted the development of pharmaceutical sludge biochar preparation and its application in advanced treatment of FQs pharmaceutical wastewater.
研究领域:
环境科学
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化学工程
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污染控制
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DOI
高影响因子
MACROMOLECULES
·
2018
·
IF 5.914
Jian Zhang,Yu-Huan Wu,Jia-Chen Wang,Fu-Sheng Du,Zi-Chen Li
We describe a straightforward synthetic strategy for a new family of functional poly(ester–amide)s (PEAs) with tertiary ester linkages via the Passerini multicomponent polymerization (Passerini-MCP) of a diacid (A2), 1,6-diisocyanohexane (B2), and four kinds of electron-deficient ketones. First, Passerini three-component reactions (Passerni-3CR) of hexanoic acid and tert-butyl isocyanide with nine kinds of ketones were investigated to evaluate the reactivities of these ketones toward Passerni-3CR. Four electron-deficient ketones, 1,1,1-trifluoroacetone (1), 1,1,1-trifluoroacetophenone (2), ethyl pyruvate (3), and 2,3-butanedione (4), were found to be excellent oxo-compounds for this Passerini-3CR. Then, the Passerini-MCP of A2 and B2 with 1, 2, 3, and 4 in CH2Cl2 was performed to generate polymers P1–P4 with tertiary ester linkages and different electron-withdrawing substituents. Polymer P5 was also prepared by the Passerini-MCP of A2 and B2 with phenylacetaldehyde (5) for comparison. Size exclusion chromatography (SEC) verified the high molecular weights (Mn up to 30.6 kDa) of these polymers. The structures of these polymers were confirmed by 1H NMR, 13C NMR, 19F NMR, and matrix-assisted laser desorption ionization mass spectroscopy. Thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) revealed that P1–P4 are less stable than polymer P5, and they are amorphous with variable glass transition temperatures (Tg) depending on the side groups. Hydrolytic degradation of P1, P4, and P5 in a mixture of acetonitrile and phosphate buffer (different pH) was investigated, and at the same pH, the degradation follows the order of P4 > P1 > P5. The static water contact angles of thin films formed by these polymers decreased from 96° (P1) to 78° (P2), 50° (P3), and finally to 32° (P4). Tensile properties of polymer P3 and P4 were characterized by dynamic mechanical analysis (DMA). P4 displayed a high tensile stress of 25 MPa with the elongation up to 200%.
研究领域:
高分子化学
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材料科学
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生物医学工程
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DOI
高影响因子
COMPOSITES COMMUNICATIONS
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2020
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IF 4.915
Dan Xue,Wen Wang,Longhai Piao,Mufang Li,Shuang Wang,Chenxue Xiang,Dong Wang
With the rapid development of electronic information technology, flexible transparent materials have been widely concerned and studied by researchers. Traditional transparent films have some problems in flexibility, transparency, or preparation method, which restrict their further development in scale production and application. Herein, we have developed a simple method by embedding the mass produced PVA- co -PE nanofibers into the PVP polymer matrix through photopolymerization method to produce a Polyvinyl Pyrrolidone/PVA- co -PE (PVP/NFs) composite film with high flexibility and transparency. Due to the nanoscale size and small refractive index contrast between nanofiber and PVP, the PVP/NFs composite film showed high light transmittance of 85.87%. In addition, the filling of PVA- co -PE nanofibers had a synergistic enhancement effect on the mechanical properties and thermal stability of PVP/NFs composite film. The tensile stress was as high as 16.6 MPa with a nanofiber content of 37.67 wt%, which was 4.05 times higher than that of the pure PVA- co -PE nanofiber film, and 2.81 times higher than that of the pure PVP film. Furthermore, the excellent flexibility of the PVP/NFs composite film enabled it to withstand a large-scale bending deformation under the action of external forces. The high flexibility, optical transparency and fast preparation made the PVP/NFs composite film a great application prospect in the intelligent electronic equipment and smart buildings.
研究领域:
材料科学
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纳米技术
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DOI
高影响因子
DYES AND PIGMENTS
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2017
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IF 3.473
Xiao-Lei Zhao,Hui-Fen Qian,Wei Huang
A family of bi-heterocyclic dyes have been first synthesized by using heterocyclic pyridone and benzothiazole components. UV−Vis spectral analyses reveal distinct spectral behaviors depending on the introduced electron-withdrawing and electron-donating groups in the benzothiazol ring as well as the polarity of solvents. Namely, nitrobenzothiazol based bi-heterocyclic dyes display more obvious solvatochromism compared with both methylbenzothiazol based ones and previously reported azobenzene based half-heterocyclic pyridone dyes. More interestingly, 1 H NMR and UV−Vis spectral results as well as single-crystal structures manifest that these dyes are in the hydrazone form in the solid state and in the non-polar solvents. However, they adopt dominating azo form in polar solvents and it can be transformed to the hydrazone form in the acidic condition, which are both different from all known half-heterocyclic pyridone dyes. In addition, transformation from hydrazone to deprotonated azo form can be achieved via metal-ion complexation, and four Ni II and Cu II complexes with different pyridone N -tails have been structurally characterized. It is noted that the ligands adopt different tridentate coordination fashions with Ni II and Cu II ions and a rare tetranuclear Cu II complex with equal Cu⋯Cu separation is obtained.
研究领域:
有机化学
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配位化学
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DOI
高影响因子
JOURNAL OF FLUORESCENCE
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2023
·Vol. 34
·期 4
·1603-1615
·
IF 2.7
Yang Yun-Shang,Yuan Yi-Zhen,Zhang Ying-Peng,Guo Hui-Chen,Xue Ji-Jun
Widely utilized in the chemical industry and agriculture, hydrazine is easily absorbed by living things and can cause physical harm when in touch for an extended period of time. As a result, a novel cinnamaldehyde chalcone C5 was produced by Friedel Crafts process and aldol condensation reaction. Triphenylamine was used as the raw material for hydrazine determination in both reactions. Chalcone C5 exhibits significant AIE behavior in a mixed mixture of ethanol and water in addition to having great selectivity and a low detection limit (0.119 nm) for hydrazine. The solvent effect test revealed a linear relationship between the Stokes shift of C5 in the solvent and the rise in solvent orientation polarization. It is important to note that C5 is not harmful to MCF-7 cells, mouse kidney cells, or pig kidney cells. Furthermore, research on cell imaging has demonstrated that probe C5 may be utilized to image the fluorescence of hydrazine in active MCF-7 cells.
研究领域:
化学
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生物医学
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材料科学
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DOI
高影响因子
Natural Product Communications
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2025
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IF 1.4
Phuong Nhung Nguyen,Ngoc Lien Nguyen,Hai Nam Pham,Phuong Khanh Nguyen,Kieu Oanh Nguyen Thi
ObjectivesPteris vittata L. is one of the hyperaccumulator plants that can grow in heavy metal-contaminated soil. This plant may tolerate metal stress through different mechanisms, eg, by producing a wide range of secondary metabolites. These compounds play an essential role in physiological function and can also serve as rich sources of chemicals for health benefit purposes. This study aims to determine the phytochemicals of plant extracts and the relationship between these profiles with pharmacological properties to predict active agents and their interaction.MethodsThe total phenolic and total flavonoid contents were measured by colorimetric assays, while the widely targeted metabolomics was applied to reveal leaf and root P. vittata metabolome. In parallel, the antioxidant and antibacterial effects of these extracts were determined by ABTS scavenging and micro-broth dilution methods. Multivariate analysis, ie, Partial Least Square Regression, calculated the correlation between metabolites and bioactivities.ResultsThe results showed the significant content of phenolics and flavonoids in plants collected from mining soils of Thai Nguyen province, Vietnam, and their potential ABTS scavenging activity. Additionally, the plant's metabolome characterized 82 compounds, mainly secondary metabolites. The multivariate analysis indicated the positive correlation among quercetin derivatives and bioactivity, suggesting the contribution of their combination, not individually, to the antibacterial effect of P. vittata.ConclusionHyperaccumulators in metalliferous soils are potential reservoirs for exploring the antibacterial agents against multi-drug resistant strains, and this effect may be exerted by additive or synergistic mechanisms of action of multiple compounds.
研究领域:
植物学
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药理学
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环境科学
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DOI
高影响因子
HIGH PERFORMANCE POLYMERS
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2025
·
IF 1.6
Chenglong Tong,Xingdi Zhang,Jiyong Zhao,Heran Nie,Zhichao Wang,Zhipeng Wang
Poly (aryl ether ketone) (PAEK) plays a critical role in the production and application of special engineering plastics. However, the traditional PAEK has some limitations in processing, such as high melt viscosity and high energy consumption. This study successfully synthesized a series of PAEK copolymers with bisphenol A and phenolphthalein side groups through nucleophilic polycondensation, aiming to reduce the high energy consumption associated with material processing. By adjusting the ratio of bisphenol A to phenolphthalein side groups, this research explores their influence on the properties of the copolymers. Comprehensive characterization using various testing methods revealed that increasing the bisphenol A content led to a decrease in heat deflection temperature and glass transition temperature. Although mechanical performance showed a slight decline, it remained comparable to other advanced engineering materials. Notably, tuning the ratio of bisphenol A to phenolphthalein significantly improved the melt rheological properties of the copolymers, reducing melt viscosity, enhancing polymer chain flexibility, decreasing crosslinking tendencies, broadening the processing window, and lowering energy consumption. This study provides a novel strategy for tailoring the performance of PAEK copolymers, offering substantial potential for further research and application. These copolymers are good candidates for next-generation high-performance engineering plastics.
研究领域:
材料科学
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高分子化学
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DOI
高影响因子
JOURNAL OF CHEMICAL RESEARCH
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2024
·
IF 1
Yinuo Wang,Yan Liang,Yutong Li,Yue Zhang,Haiwen Song,Aibing Ke
Furfural and nitromethane were utilized as raw materials for the synthesis of the herbicide-safe agent Furilazole through the Henry reaction, nitro reduction and addition-cyclization-acylation. A comprehensive investigation into the involved reaction processes was conducted, leading to the identification of barium hydroxide octahydrate as the catalyst for the Henry reaction. The continuous use methodology of the excess catalyst was determined through TGA/DSC curve analysis, and a rational purification method for Henry reaction products was proposed. The nitro reduction reaction employed Pd/C catalysis, while the subsequent addition-cyclization-acylation reaction was achieved in a single step. Five impurities affecting the reaction process were identified, and their potential mechanisms of formation were postulated. Optimization of synthetic process conditions was carried out for all involved reactions. The structures of intermediates, impurities, and products were characterized using NMR, HRMS, TGA/DSC and FTIR.
研究领域:
化学合成
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农药科学
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DOI
高影响因子
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
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2024
·Vol. 60
·期 10
·1999-2003
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IF 0.8
Li C. L.,Wang S. Y.,Zhan M. R.,Chen C. C.,Wang Z. X.
Chiral monosubstituted cyclohexanediamine catalyst, namely (1 R ,2 R )-2-(piperidin-1-yl)cyclohexan-1-amine ( Cat1 ) has been efficiently synthesized and used to catalyze the aldol reaction of cyclohexanone and 2-(trifluoromethyl)benzaldehyde to obtain ( R )-2-{( S )-hydroxy[2-(trifluoromethyl)phenyl]methyl}cyclohexan-1-one. The catalyst (20 mol %) provided high yield (up to 85%) and excellent enantioselectivity (95.6% ee ) in water solution in three parallel tests.
研究领域:
有机化学
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催化化学
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DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2024
·
IF 4
Beidou Zhou,Xuemei Liao,Shuyi Liu,Guiqing Gao,Yanting Gao,Wanting Gan,Jialing Ke,Yuxin Wu,Feifei Wang,Baocheng Huang,Wanjing Yang,Renping Ye,Yihui Liu,Yicong Lin
Using Eaton's reagent or boron trifluoride ether, 24 compounds were synthesized in a 1- or 2-step reaction, with the conversion of the methoxy group to the hydroxyl group. Next, the in vitro antitumor activity of all compounds and the antioxidant activity of compounds 1 to 3 were investigated. Compounds 7, 13, 15, 17, 18, 20, 22 , and 24 exhibited strong antitumor activity and were considered promising compounds. Among them, compounds 7, 13 , and 18 exhibited very strong inhibitory activity against HL-60 cells with IC 50 values of 0.55, 0.29, and 0.72 μM, respectively. Furthermore, compounds 1 to 3 exhibited moderate antioxidant activity and their mechanism of action was further validated by computational chemistry. Finally, the antitumor mechanism of the above 8 compounds was investigated through network pharmacology and molecular docking, and 19 key genes and 20 pathways were obtained. These results will allow future development of benzophenone and its derivatives.
研究领域:
药物化学
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肿瘤学
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计算生物学
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DOI
高影响因子
Scientific Reports
·
2024
·Vol. 14
·期 1
·1-15
·
IF 3.8
Yuan Liye,Zhi Jieying,Wang Congwei,Wang Junwei,Cao Lijuan,Yang Yu,Zhao Guojing,Lu Chunxiang,Lu Xiaoxuan
Single-layer isophorone diisocyanate (IPDI) are one of the most popular self-healing microcapsules but suffers from low shell strength, poor heat resistance, stability and aging properties. In this paper, IPDI microcapsules were encapsulated into double-layer phenolic (PF)/polyurethane (PU) by a two-step process involving interfacial polymerization and in-situ polymerization. The prepared microcapsule composites were comprehensively characterized for their physical and chemical properties using optical microanalysis, scanning electron microscope, Fourier transform infrared spectroscopy, thermal gravimetric analysis and depth-sensing indentation analysis. Compared with the single-layer PU-IPDI microcapsule counterpart, the mechanical performance, thermal resistance, aging property and environmental stability of double-layer PF/PU-IPDI microcapsules were significantly improved. The epoxy coating was enhanced with the incorporation of 10 wt.% PF/PU-IPDI microcapsules, whose self-healing performance was evaluated by scratch corrosion test. The results demonstrated successful repair of coating scratches, along with the absence of corrosion on the coated steel substrate soaked in a 10 wt.% NaCl solution for 7 days. By comparing the tensile strength of epoxy coating before and after crack formation, it could be found that the self-healing efficiency was 57.9% when loaded with 10 wt.% of PF/PU-IPDI microcapsules in coating. This study highlights that the rational design of double-layer microcapsules integrated into the epoxy coating matrix could provide excellent anti-corrosion and self-healing properties.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
POLYMER COMPOSITES
·
2022
·Vol. 43
·期 6
·3880-3889
·
IF 3.531
Shuai Yang,Yang He,Jinsong Leng
In this paper, boron nitride (BN) sheets, as two-dimensional thermal conductive fillers, were integrated into shape memory poly(aryl ether ketone) (PAEK) matrix to improve the response speed of actuators. The thermal conductivity of composites was found to be positively correlated with the content of BN sheets. Significantly, a highest in-plane thermal conductivity of 2.66 W m −1 K −1 was obtained, which resulted in the increase of the recovery speed of the PAEK/BN actuators from 18 to 6 s. Besides, the integration of BN sheets improved the shape memory effect of PAEK matrix, including the higher shape recovery ratio (up to 99.9%) and fixity ratio (over 97%). In addition, through the assembling of four components with designed BN contents, we achieved the interesting staged shape recovery behaviors for PAEK/BN composite actuators, which enabled programmable and smart manipulations. These fabricated PAEK/BN composite actuators with rapid response and staged deformation behaviors possessed the wide utilization potential in smart devices.
研究领域:
材料科学
·
智能材料
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）