Nature Communications
·
2025
·
IF 15.7
Guo Yuan,Yun Yuzhe,Xiang Wenzhi,Xu Guorui,Sun Luye,Xu Wei
On-surface synthesis recently enabled access to generate a series of cyclo[ n ]carbons (C n , up to C 26 ) via delicately designed precursors. However, for larger cyclocarbons, synthesis of the corresponding precursors is being challenged. Here, we report another strategy for synthesizing larger cyclocarbons via the coupling and ring-opening reactions from smaller ones. We chose C 10 as the precursor, and induce the coupling and ring-opening reactions via tip manipulation to successfully generate C 20 and C 30 . Bond-resolved atomic force microscopy imaging unambiguously reveals the polyynic structure of C 30 , aligning with theoretical prediction. This approach establishes a new pathway to access larger cyclocarbons, and potentially enables controlled polymerization of cyclocarbons.
研究领域:
纳米材料
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表面化学
·
分子纳米技术
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碳化学
·
扫描探针显微学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2015
·
IF 0.633
Fang-Ming Wang,Dan Bao,Bing-Xiang Hu,Ze-Yu Zhou,Deng-Deng Huang,Li-Zhuang Chen,Yuan-Yuan Dan
A series of novel 10-substituted 3,6-diphenyl-9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives synthesised by condensation of different amines with xanthenes, was prepared from 5-phenylcyclohexane-1,3-dione and aromatic aldehydes by a Knoevenagel and Michael reaction and cyclisation catalysed by a trace of l-proline at room temperature. In addition, the molecular structure of a xanthene was determined by single-crystal X-ray diffraction analysis.
研究领域:
有机化学
·
药物化学
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DOI
高影响因子
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
·
2019
·Vol. 50
·期 10
·4827-4838
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IF 1.985
Liu Jun-Kai,Zhang Guo-Hua,Sun Guo-Dong
We propose a process to produce ultrafine W-10 wt pct Cu composite powders by reducing the mixtures of copper tungstate (CuWO 4 ) and tungsten trioxide (WO 3 ) (from the calcination of a mixture of ammonium paratungstate and copper nitrate trihydrate) with carbon black and hydrogen. First, ultrafine pre-reduced tungsten-copper (W-Cu) powders containing a small amount of WO 2 were produced by reducing mixtures of CuWO 4 and WO 3 with insufficient carbon black; then the obtained products were further reduced by hydrogen to remove the residual oxygen. This method provides a simple and low-cost route to prepare ultrafine W-10 wt pct Cu composite powders. The composite powders were sintered at different temperatures [1323 K (1050 °C), 1373 K (1100 °C), 1423 K (1150 °C), 1473 K (1200 °C), and 1523 K (1250 °C)] for 3 hours. A maximum densification of the obtained compact was achieved at a sintering temperature of 1523 K (1250 °C), with a relative density, Vickers hardness and thermal conductivity of the W-10 wt pct Cu composites of 97.8 pct, 365 HV and 165 W/m K, respectively.
研究领域:
材料科学
·
冶金工程
✓ 已验证
DOI
高影响因子
ACS Applied Energy Materials
·
2022
·
IF 6.959
Yuanyi Liu,Tianxing Xiang,Bing Zhang,Jize Wang,Xinxin Yu,Yueyue Xiao,Junyan Xiao,Zhiliang Ku,Yong Peng
Current CsPbBr3 perovskite solar cells still suffer from a high open-circuit voltage (Voc) loss due to the high defect density. Herein, we demonstrate a strategy to passivate defects and induce Fermi level modification through BaI2 doping. The carrier lifetime is significantly extended after adding BaI2. In addition, the Fermi level is changed as Ba2+ enters the crystal lattice, which increases the built-in potential and promotes the transport of carriers. As a result, the optimized thermally evaporated device shows a record Voc of 1.551 V and an improved power conversion efficiency of 10.09% as well as excellent thermal stability.
研究领域:
材料科学
·
光伏技术
✓ 已验证
DOI
高影响因子
Journal of Energy Chemistry
·
2024
·
IF 14
Haixuan Yu,Zhiguo Zhang,Huaxia Ban,Xiongjie Li,Zhirong Liu,Junyi Huang,Wanpeng Yang,Yan Shen,Mingkui Wang
The lead-free inorganic perovskite CsSnI 3 is considered as one of the best candidates for emerging photovoltaics. Nevertheless, CsSnI 3 -based perovskite solar cells experience a significant drop in performance due to the nonradiative recombination facilitated by trapping. Here, we show an electron donor passivation method to regulate deep-level defects for CsSnI 3 perovskite with electron donor pyrrole. Experimental observations combined with theoretical simulations verify that the saturation of Tin dangling bonds with pyrrole on the CsSnI 3 surface via a Lewis acid-base addition reaction can significantly reduce the density of deep-level defects. Consequently, the printable mesoporous perovskite solar cells with an FTO/compact-TiO 2 /mesoporous-TiO 2 /Al 2 O 3 /NiO/carbon framework device structure penetrated with CsSnI 3 achieve a power conversion efficiency of up to 10.11%. To our knowledge, this represents the highest efficiency reported to date for lead-free perovskite-based printable mesoporous solar cells. Furthermore, the unencapsulated devices demonstrated remarkable long-term stability, retaining 92% of their initial efficiency even after 2400 h of aging in a nitrogen atmosphere.
研究领域:
材料科学
·
太阳能电池技术
✓ 已验证
DOI
高影响因子
HUMAN REPRODUCTION
·
2022
·Vol. 37
·期 6
·1287-1296
·
IF 6.353
Zhu Yanwen,Wang Bian,Zhu Qianqian,Ye Jing,Kuang Yanping
STUDY QUESTIONHow did the sexual frequency change and what are the related influencing factors among infertile Chinese couples over the past 10 years?SUMMARY ANSWERSexual frequency has declined among infertile Chinese couples over the past decade, with such declines being most pronounced for women between the ages of 18 and 39.WHAT IS KNOWN ALREADYMany researchers have explored trends in coital frequency and variables associated among healthy individuals in other nations. There have been major changes in all aspects of Chinese life and society over the past decade, including two major fertility policy adjustments. The sexual habits of infertile couples in China remain poorly understood and warrant further investigation.STUDY DESIGN, SIZE, DURATIONA retrospective cohort study of 51 150 infertile couples that visited our facility between January 2011 and December 2020 at a tertiary care academic medical centre.PARTICIPANTS/MATERIALS, SETTING, METHODSThe primary outcome for this study was whether couples had engaged in sexual intercourse ≤4 times/month or >4 times/month. Multivariable logistic regression analyses were performed to detect the association between the variables and sexual frequency. Analyses were further performed to determine whether observed trends remained evident in women from different age subgroups. To assess whether these trends differed before and after the introduction of the universal two-child policy in China (January 2016), we additionally assessed trends in these age subgroups of women relative to the time at which this policy was introduced.MAIN RESULTS AND THE ROLE OF CHANCEThe proportion of couples reporting having engaged in sexual intercourse >4 times/month fell over the past decade from 62.7% (2011–2013) to 55.9% (2014–2015) to 52.7% (2016–2020). Declines in sexual frequency were evident for women between the ages of 18 and 39 (P < 0.05), whereas no such changes were evident for women between the ages of 40 and 50. Younger men and women, as well as individuals with a less than junior college education level, reported higher frequencies of sexual intercourse. For women, being remarried and having a more recent diagnosis of infertility were associated with increased coital frequency. This frequency decreased progressively for women as BMI values increased. There was no detected relationship between coital frequency and nationality or history of prior births.LIMITATIONS, REASONS FOR CAUTIONThese analyses were dependent on self-reported data, and may thus have been impacted by the over- or under-reporting of sexual frequency as a consequence of social desirability bias. In addition, not all potentially relevant variables were assessed in all analyses, and certain potentially relevant variables such as family income or pornography use were not measured in any analyses.WIDER IMPLICATIONS OF THE FINDINGSSexual frequency is closely related to infertility risks. This general downward trend in sexual frequency may warrant concern. At present, these reductions remain an interesting yet unexplained topic worthy of further study.STUDY FUNDING/COMPETING INTEREST(S)This study was funded by the National Key Research and Development Program of China (Grant no. 2018YFC1003000) and the National Natural Science Foundation of China (Grant no. 81771533). The authors declare no conflict of interest.TRIAL REGISTRATION NUMBERN/A.
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 84
·68476-68484
·
IF 3.84
Qinqin Luo,Yanchao Yuan,Chunlei Dong,Shumei Liu,Jiangqing Zhao
5,10-Dihydro-phenophosphazine-10-oxide (DPPA) served as a co-curing agent for 4,4′-diaminodiphenylmethane in the curing reaction of bisphenol A diglycidyl ether (DGEBA) epoxy resin (EP). 1H NMR tracking the reaction of DPPA with DGEBA revealed that the P–H bond in DPPA had a higher reactivity with the epoxy group than the N–H bond. DPPA could promote the curing reaction of DDM with DGEBA. DPPA endowed the epoxy resin with a high flame-retardant efficiency due to the unique combination of phosphorus and nitrogen in the phenophosphazine ring. The cured epoxy resin could achieve a V-0 rating in the UL-94 test with a limiting oxygen index (LOI) of 33.6% at only 2.5 wt% DPPA. The reduced peak heat release rate and total heat release, and increased char yield further verified the excellent flame retardancy of EP. The flame-retardant mechanism of the epoxy resin was investigated by thermogravimetry-Fourier transform infrared spectrometry (TG-FTIR), scanning electron microscopy, elemental analysis and FTIR spectrometry. The results indicated that DPPA catalyzed the formation of the rigid intumescent char and the generation of the blowing-out effect in the epoxy resin matrix.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
BIOELECTROCHEMISTRY
·
2025
·
IF 4.5
Nianting Xue,Hao Sun,Shihang Lu,Yizhen Yu,Wenyan Ma,Guangzhou Liu,Wenwen Dou
Microbiologically influenced corrosion (MIC) poses a serious threat to the structural integrity of Cu Ni alloys under marine service conditions. This study proposed a novel antibacterial peptide (Tcs) combined with Alkyl Dimethyl Benzyl Ammonium Chloride (ADBAC) to inhibit MIC in 90/10 Cu Ni alloy induced by Desulfovibrio ferrophilus IS5. Bacterial counts, environmental parameters analysis, surface morphological analyses, weight loss measurements, and electrochemical tests were conducted, through which the antibacterial and corrosion inhibition effects were demonstrated. The results showed that 180 ppb Peptide Tcs (180 Tcs) alone exerted almost no inhibitory effect on D. ferrophilus IS5, whereas a significant concentration-dependent enhancement was observed when Peptide Tcs was combined with 20 ppm ADBAC (20 ADBAC). Specifically, the 20 ppm ADBAC +180 ppb Peptide Tcs (20 ADBAC-180 Tcs) combination further reduced sessile bacterial counts by one order of magnitude compared to 20 ADBAC alone, while the weight loss rate and maximum pitting depth decreased by approximately 86 % and 61 %, respectively. These findings provide new insights into optimizing traditional biocide systems with small antimicrobial peptides and developing green, efficient strategies for controlling marine MIC.
研究领域:
材料科学
·
微生物学
·
腐蚀工程
·
海洋技术
·
抗菌肽
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Fei Guo,Lingfeng Wang,Huixin Dong,Pengyu Yan,Shishuo Wang,Qingquan Li,Shaohua Yin,Guoli Zhou,Ning Zhang,Xiao Wu,Yuandong Jia,Gaohong He,Xiaobin Jiang
High ion-selectivity and robust long-term stability are critical performance metrics for nanofiltration (NF) membranes targeting lithium extraction from high-salinity brines with impurities and high magnesium lithium ratios. Herein, a positive and negative heterostructure dual-layer NF membrane with sub-10 nanometer PA layer on 2D Zn-TCPP nanosheets through interfacial polymerization method coupled with vacuum assisted filtration was constructed. PA layer with positively charge on the top performed as the ‘shield’ that effectively retains Mg2+, while negatively charged Zn-TCPP coupled with uniform pores performed as the ‘accelerator’ to facilitate Li+ permeate. The addition of Zn-TCPP can increase the membrane free volume fraction and construct effective screening channels. An appropriate amount of Zn-TCPP nanosheets can construct PA layers as thin as 5 nm and lead to the best Li/Mg separation performance. (Water permeance of 6.79 L⋅m−2⋅h−1 bar−1 over 360 hours continuous operation when Mg/Li ratio is 50:1, and Li+/Mg2+ separation factor is 80.79). In the ternary metal ions solution tests (Li⁺, Mg²⁺, X⁺, where X = Na⁺ or K⁺ with doubled concentration), Li+/Mg2+ separation factor remains still above 40. The DFT simulations and molecular dynamics reveal The transmembrane energy barrier for Mg²⁺ significantly exceeds that for Li⁺ across the membrane. The adsorption heights of ions on Zn-TCPP in a stable state, the different ion perforation energy and ion diffusion rate furtherly explain the reason for the membrane with excellent separation performance.
研究领域:
材料科学
·
膜技术
·
分离科学
·
能源材料
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jia Gao,Jing Ren,Hanjie Ye,Wenhui Chu,Xuankai Ding,Lingzhi Ding,Yongqian Fu
Angiogenesis is pivotal for osteogenesis during bone regeneration. A hydrogel that promotes both angiogenesis and osteogenesis is essential in bone tissue engineering. However, creating scaffolds with the ideal balance of biodegradability, osteogenic, and angiogenic properties poses a challenge. Thymosin beta 10 (TMSB10), known for its dual role in angiogenesis and osteogenesis differentiation, faces limitations due to protein activity preservation. To tackle this issue, ZIF-8 was engineered as a carrier for TMSB10 (TMSB10@ZIF-8), and subsequently integrated into the self-assembled sericin hydrogel. The efficacy of the composite hydrogel in bone repair was assessed using a rat cranial defect model. Characterization of the nanocomposites confirmed the successful synthesis of TMSB10@ZIF-8, with a TMSB10 encapsulation efficiency of 88.21 %. The sustained release of TMSB10 from TMSB10@ZIF-8 has significantly enhanced tube formation in human umbilical vein endothelial cells (HUVECs) in vitro and promoted angiogenesis in the chicken chorioallantoic membrane (CAM) model in vivo . It has markedly improved the osteogenic differentiation ability of MC 3 T3-E1 cells in vitro . 8 weeks post-implantation, the TMSB10@ZIF-8/ Sericin hydrogel group exhibited significant bone healing (86.77 ± 8.91 %), outperforming controls. Thus, the TMSB10@ZIF-8/Sericin hydrogel, leveraging ZIF-8 for TMSB10 delivery, emerges as a promising bone regeneration scaffold with substantial clinical application potential.
研究领域:
生物医学工程
·
组织工程
·
材料科学
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2024
·
IF 6.3
Yu He,Chenxi Zhao,Zecheng Lu,Ning Guo,Hongmei Luan,Yanchun Yang,Ruijian Liu,Chengjun Zhu
Indium tin oxide (ITO) and intrinsic ZnO (i-ZnO) are usually used as the window layer of Cu 2 ZnSn(S,Se) 4 (CZTSSe) solar cells within a typical structure. The optoelectronic properties of the window layer play a crucial role in determining the efficiency of solar cells. In this work, two types of CZTSSe solar cells with and without i-ZnO layers were fabricated using dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) as solvents, respectively. The impact of the window layer on the performance of CZTSSe solar cells was investigated. The results suggest that the device without i-ZnO still exhibits a high power conversion efficiency (PCE) compared to conventional bilayer i-ZnO/ITO structures. By removing i-ZnO and optimizing the thickness of ITO, the highest power conversion efficiency (PCE) of DMSO and DMF-based CZTSSe solar cells has been up to 10.17% and 10.27%, respectively, with an increase in open-circuit voltage (V OC ) of 15 mV (in DMSO system) and 10 mV (in DMF system), as well as an enhancement in fill factor (FF) by ∼5 percentage points. These performance improvements are mainly attributed to the reduction of series resistance (R s ) of the window layer due to the removal of i-ZnO layer. Further analysis shows that the generation and collection of photon-generated carriers in CZTSSe solar cells can be affected by the optimized window layer due to optical interference effects and its resistance. Our research may provide insights for the preparation of high efficient CZTSSe solar cells with new structures of the i-ZnO free window layer.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Nanomedicine
·
2017
·
IF 4.3
Yang Liu,Dan Li,Xinhong Guo,Haiwei Xu,Zhi Li,Yanling Zhang,Chuanjun Song,Ruhan Fan,Xing Tang,Zhenzhong Zhang
We synthesized a pH-responsive conjugate of 10-hydroxycamptothecin-thiosemicarbazide-linear polyethylene glycol 2000 (PEG2000). The conjugate was confirmed by matrix-assisted laser desorption time of flight mass spectrometry, 1 H NMR, and 13 C NMR. The water solubility of the prodrug was increased by over 3,000 times; much longer body circulation time, higher tumor-targeting ability, and reduced toxicity were observed, compared with commercial 10-HCPT injection. The linker contains a pH-sensitive hydrazone bond, which breaks under low pH conditions in the tumor microenvironment. The conjugates showed good stability in phosphate-buffered saline (pH 7.4) and rat plasma. This amphiphilic conjugate could self-assemble into nanosized micelles of 80–100 nm. Cytotoxicity assay results indicate significantly higher efficacy of the conjugate (IC 50 [half maximal inhibitory concentration] =0.117 µM on SW180 cells) than 10-HCPT solution (IC 50 =0.241 µM on SW480 cells). Cellular uptake analysis suggested its rapid internalization and nuclear transport. Pharmacokinetic analysis of the conjugates demonstrated that the conjugate circulated for a longer time in the blood circulation system ( T 2/1 =10.516±1.158 h) than did 10-HCPT solution ( T 2/1 =1.859±1.385 h), and that it also enhanced the targeting and mean residence time (MRT 0–inf =39.873±4.549 h) in the tumor site, compared with 10-HCPT (MRT 0–inf =9.247±1.026 h). Finally, the conjugate demonstrated an increased tumor growth inhibition effect (TIR =82.66%±7.175%) in vivo and lower side effects than 10-HCPT (TIR =63.85%±5.233%). This prodrug holds great promise in improving therapeutic efficacy and overcoming multidrug resistance.
研究领域:
药学
·
药物递送系统
·
癌症治疗
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）