ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES
·
2023
·Vol. 78
·期 10
·921-926
·
IF 1.8
Cong Liu,Junshen Xing,Zheng Liu,Wenlin Feng
BaSr 2 (PO 4 ) 2 : 4 %Eu 3+ , 4 % A ( A = Li + , Na + , K + ) phosphors were prepared by high-temperature solid-phase method. The crystal structure, photoluminescence properties, thermal stability, chromaticity coordinates, and fluorescence lifetime of the samples were investigated. The excitation and emission spectra of the samples are broadbands and the maximum peak of the emission spectrum is located at 619 nm. Among three charge compensators, the luminescence intensity is optimal for Li + co-doping case, and the quenching temperature of the typical sample is about 500 K. the fluorescence lifetime
τ
is 1469.6 ns, and the chromaticity coordinates exhibit a strong red emission. The present phosphor has a potential application for white light-emitting diodes (LEDs) under the near-ultra violet (n-UV) light excitation.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
Canadian Journal of Chemistry
·
2022
·Vol. 100
·期 6
·
IF 1.051
Junyong Sun,Xian Liu,Like Chen,Lijun Peng,Xitian Peng,Tian Gan
Herein, polyvinylpyrrolidone-stabilized Au nanorods were controllably implanted into ZIF-8 to form a well-uniformed AuNRs@ZIF-8 electrocatalyst with a multicore-shell structure. After characterizing the chemical and physical properties, a novel electrochemical sensing platform was fabricated for 2-chlorophenol (2-CP) monitoring based on the AuNRs@ZIF-8 modified glassy carbon electrode. Due to the unique electrochemical property of AuNRs cores and ultra-porous architecture of ZIF-8 shell, the electrocatalyst would effectively accelerate the electron transfer and greatly improve the electrochemical response of 2-CP. Under the optimized experimental conditions, the oxidation peak current of 2-CP enhanced linearly with the increase of its concentration between 0.010 and 40 μM, and the limit of detection was 3.6 nM based on S/N = 3. Meanwhile, the prepared AuNRs@ZIF-8 electrode showed favorable stability, reproducibility, and selectivity, which could be applied to the accurate analysis of 2-CP in aquaculture with standard addition recovery ranging from 96.67% to 104.0%.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
ECS Journal of Solid State Science and Technology
·
2021
·Vol. 10
·期 10
·106011
·
IF 2.07
Jie Yang,Bo Ruan,Wang Ni,Lung-Chang Tsai,Ning Ma,Dean Shi,Tao Jiang,Fang-Chang Tsai
Carbon dots (CDs) has been widely applied in LED diodes, sensing and bioimaging. However, the fluorescence property of CDs is limited because of the solid-state aggregation-caused quenching (ACQ). Metal-organic frameworks (MOFs), due to their high surface area, porosity and tunable pore size, are considered suitable hosts to inhibit the ACQ of CDs. Herein, the Zr-MOFs (UiO-66-(OH)2) is chosen as a host to encapsulate CDs. The dual-emitting CDs@MOFs system is constructed, which overcomes the problem of solid-state aggregation-caused quenching of carbon dots to gain the blue-emitting CDs@UiO-66-(OH)2. With the volume of CDs increased, the fluorescence of CDs@UiO-66-(OH)2 has changed simultaneously. When the volume reaches 3 ml, CDs@UiO-66-(OH)2 begin to cause fluorescence quenching. The correlated color temperatures (CCT) of CDs@UiO-66-(OH)2 are transformed from cold light to warm light. That can be further researched in electroluminescent diodes, ion-sensor, environmental monitoring, biological imaging and developments in other related biochemical fields.
研究领域:
材料科学
·
生物成像
·
传感技术
✓ 已验证
DOI
高影响因子
Journal of Environmental Sciences
·
2010
·
IF 1.412
Shuyan Zang,Bin Lian,Juan Wang,Yanjie Yang
To explore biodegradation of 2-naphthol and its metabolites accumulated in wastewater treatment, a series of bio-degradation experiments were conducted. Two main metabolites of 2-naphthol, 1,2-naphthalene-diol and 1,2-naphthoquinone, were identified by high-performance liquid chromatography with standards. Combining fungus Aspergillus niger with bacterium Bacillus subtilis in the treatment enhanced 2-naphthol degradation efficiency, lowered the accumulation of the two toxic metabolites. There were two main phases during the degradation process by the kinetic analysis: 2-naphthol was first partly degraded by the fungus, producing labile and easily accumulated metabolites, and then the metabolites were mainly degraded by the bacterium, attested by the degradation processes of 1,2-naphthalene-diol and 1,2-naphthoquinone as sole source of carbon and energy. Sodium succinate, as a co-metabolic substrate, was the most suitable compound for the continuous degradation. The optimum concentration of 2-naphthol was 50 mg/L. The overall 2-naphthol degradation rate was 92%, and the COD Cr removal rate was 80% on day 10. These results indicated that high degradation rate of 2-naphthol should not be considered as the sole desirable criterion for the bioremediation of 2-naphthol-contaminated soils/wastewater.
研究领域:
环境科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2020
·Vol. 34
·期 4
·e5451
·
IF 3.14
Shuang Huang,Xi Hong,Yong Sun,He-Zhen Cui,Quan Zhou,Yue-Jian Lin,Xiu-Feng Hou
Six tridentate NNN ligand precursors derived from 2-(pyridin-2-yl)benzo[d]thiazole(PBT) with different linkers, PBT NN X N (X = NH, NMe, O, S) ( 1a – 1f ), have been successfully prepared. The electronic properties of PBT NN X N ligands are well tunable by differing linkers between PBT skeleton and the pyridine ring, and/or by introducing electron-donating/withdrawing groups on the pyridine ring (R = OMe or F). The ligand precursors and representative complexes Ru ( PBT NN NH N )Cl 2 (PPh 3 ) ( 2a ), Ru ( PBT NN NMe N )Cl 2 (PPh 3 ) ( 2b ), and Ru ( PBT NN S N )Cl 2 (PPh 3 ) ( 2f ) have been characterized by NMR spectroscopy, high-resolution mass spectroscopy, and Fourier transform infrared (FT-IR). The molecular structures of 1f , 2a , and 2f have been determined by X-ray diffraction study. The results indicate that PBT NN NH N ligand in the complex presented coplanar with two five-membered chelating rings. It should be noted that 2a featuring a NH group exhibits superior performance compared to those with other linkers (such as NMe, O, or S). A variety of heterocyclic and aromatic nitriles with aromatic and aliphatic alcohols have been explored in α -alkylation for good to excellent yields. Based on kinetic experiments and mechanistic studies, a proposed mechanism was put forward. Ru-H species and benzaldehyde, which was oxidized from benzyl alcohol, were detected in the catalytic cycle.
研究领域:
无机化学
·
有机化学
·
催化
·
材料科学
✓ 已验证
DOI
高影响因子
PHARMACOLOGICAL RESEARCH
·
2025
·
IF 10.5
Huan Shi,Biaobiao Wang,Zhiwei Shi,Huilin Ma,Yunmei Li,Ying Liu,Yu Zhao,Nan Xia,Chao Wu,Yu Gao
Glioma, the most prevalent primary intracranial tumor, presents significant clinical treatment challenges due to its high invasiveness and therapeutic resistance. Therefore, the development of a targeted therapeutic agent that is both highly effective and low in toxicity is crucial. In this research, we aimed to design a bionic mesoporous selenium nanoparticle (ACMLMSeP) functionalized with paclitaxel and Ang-2 for nasal administration as a targeted treatment approach for glioma. Nasal administration facilitates direct delivery of drugs to the brain through the olfactory nerve, thereby circumventing the protective mechanisms of the blood-brain barrier. Mesoporous selenium (MSe) significantly enhances the loading capacity for insoluble drugs while improving their water solubility. The functionalization of MSe enables slow drug release and facilitates targeted drug accumulation. Moreover, accumulated nano-selenium promotes reactive oxygen species (ROS) production, induces autophagy, and synergizes with drugs to accelerate apoptosis in tumor cells. Analysis using Transmission Electron Microscopy (TEM) images and Dynamic Light Scattering (DLS) indicated that ACMLMSe has an average particle size of roughly 135 nm. Results from in vitro release assessments indicated that the ACMLMSeP sustained the release of the drug, reaching a total release rate of 74.96 ± 2.34 % within 24 h. Cellular uptake studies and in vivo imaging showed the strong targeting capabilities of the ACMLMSeP nanoparticles. Furthermore, the results obtained from the MTT assays, flow cytometry analysis, immunofluorescence staining, and in vivo antitumor evaluations collectively revealed that ACMLMSeP effectively inhibited proliferation while promoting apoptosis in C6 cells. In summary, these experimental findings clearly suggest that ACMLMSeP may serve as a promising biomimetic nanosystem for the targeted treatment of brain glioma.
研究领域:
药学
·
肿瘤学
·
纳米医学
·
神经科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2014
·
IF 4.058
Bo Yang,Jiaxing Zhang,Yunfei Zhang,Shubo Deng,Gang Yu,Jinhua Wu,Hong Zhang,Jianhong Liu
The low-cost Al–Ni alloy particles could achieve high dechlorination activity for 2-chlorophenol (2-CP) with the addition of tetrasodium EDTA (EDTA-4Na) in this study. The species of chelating agent, pH values, and the dosages of chelating agent were investigated for their effects on dechlorination efficiency of 2-CP in solution. EDTA-4Na presented the highest promoting effect for Al–Ni alloy in dechlorination process compared with other chelating agents, which is closely correlated with the conditional stability constant ( K f ′ ) of chelates formed. The optimized result showed that 0.389 mM of 2-CP was completely dechlorinated into phenol using 10 g L −1 of Al–Ni alloy and 10 mM of EDTA-4Na at initial pH 11.0 within 45-min reaction. Recycling tests of the alloy particles showed that Al–Ni alloy coupling with EDTA in aqueous solution exhibited high dechlorination activity and stability before being exhausted. The maintenance of Al–Ni alloy activity for dechlorination was mainly attributed to the promoting effect of EDTA-4Na on Al corrosion, the inherent structure of alloy with Ni crystal homogeneously dispersing into Al substrate, and the change of its surface morphology with more active sites formed by EDTA corrosion.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
·
2013
·Vol. 2013
·期 32
·7411-7420
·
IF 3.344
Zhengkai Chen,Weijun Yang,Lijun Xu,Lili Zhang,Maozhong Miao,Hongjun Ren
Graphical Highly substituted 2-hydroxyflavanones can be obtained through a tandem O -arylation/hydroxylation process from triazenylaryl-substituted diketones in the presence of a Lewis acid. A transition-metal-free tandem O -arylation/hydroxylation approach has been developed for the efficient synthesis of highly substituted 2-hydroxyflavanones from triazenylaryl-substituted diketones. The intermediate benzopyrylium cation may be involved in these reactions.
研究领域:
有机化学
·
药物化学
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Tiantian Wang,Jianhong Wei,Furong Shi,Hejie Wang,Jinye He,Xudong Lv,Yuan Zhou,Pengzhi Guo,Chenglong Wang,Yangjun Xia
In recent years, polymerized small molecule acceptors (PSMAs) have emerged as a promising strategy that combines the strong absorption of small molecules with the film-forming ability and stability of polymers, thereby greatly boosting the performance of all-polymer solar cells (all-PSCs). We designed a non-fused acceptor, DTBT-IC, and its polymeric counterpart, PDTBT-Br-T, by selecting DTBT as the core, bithiophene as the π-bridge, and IC as the terminal group. PDTBT-Br-T was synthesized via Stille coupling and used with PM6 as the donor to fabricate organic solar cells. The PDTBT-Br-T-based device delivered superior performance, with a VOC of 1.050 V, JSC of 9.32 mA cm−2, FF of 45.33%, and a PCE of 4.44%, outperforming the DTBT-IC-based counterpart. Morphological and structural analyses revealed that PDTBT-Br-T exhibits more ordered backbone stacking and defined phase separation, enhancing exciton dissociation and charge transport, and suppressing energy loss. The study highlights that polymerization of DTBT-IC enhances intermolecular packing and microstructure, offering critical design insights for efficient all-PSCs.
研究领域:
材料科学
·
高分子化学
·
有机电子学
·
光伏技术
✓ 已验证
DOI
高影响因子
Molbank
·
2024
·Vol. 2024
·期 2
·M1828
·
IF 0.6
Zhongwei Wang,Lin Song,Yukun Qin
This study aims to develop an efficient and green one-pot method for the synthesis of 6-en-1-yl furan-2-carboxylic acid heptyl ester. Initially, using furfural as the starting substrate, hept-6-en-1-yl furan-2-carboxylate was prepared using a one-pot method. This study developed a new experimental scheme for preparing ester compounds, using cuprous chloride as a catalyst and tert butyl hydrogen peroxide as an oxidant to prepare furoic acid. Without the need for intermediate treatment, the target product can be directly obtained from furfural by adding 7-bromo-1-heptene, TBAB, and potassium carbonate. This method effectively utilizes furfural as a platform chemical, demonstrating its potential for synthesizing high-value chemicals. The entire synthesis process is simple and efficient, following the principles of green chemistry.
研究领域:
有机化学
·
绿色化学
·
合成化学
✓ 已验证
DOI
高影响因子
Journal of Pharmaceutical Innovation
·
2025
·Vol. 20
·期 6
·1-17
·
IF 2.7
Lin Jinsheng,Wu Qilin,Liu Xueyang,Cao Renjian,Yong Qiyun,Li Dan,Chen Wenbin,Li Min,Shen Weiyang
Purpose This study intended to investigate two unknown impurity peaks (DP-1 and DP-2, at 0.29% and 0.20%, respectively) observed during the stability testing of brexpiprazole drug substance, which exceeded the unspecified impurity threshold (≤ 0.10%) and triggered an out-of-specification (OOS) investigation in a GMP environment. The objectives are to identify their structures, determine whether they are true impurities or artificial degradants, and establish appropriate control procedures for the pharmaceutical analysis of brexpiprazole. Methods The impurities were initially characterized using LC-UV/PDA high-resolution MS n ( n = 1 to 3), which identified DP-1 as an isomer of brexpiprazole and DP-2 as a dimer. Further structural elucidation of DP-1 was performed using semi-preparative HPLC and 1D/2D NMR spectroscopy. Forced degradation studies were conducted under photolytic conditions to confirm the formation of DP-1 and DP-2, with freshly prepared solutions kept in the dark as controls. Results DP-1 and DP-2 are both photo-degradants of brexpiprazole in solution. DP-1 is confirmed as an intramolecular [2 + 2] cycloaddition product of brexpiprazole, which is a novel and unreported impurity found in the product of brexpiprazole. DP-2 is identified as an intermolecular [2 + 2] cycloaddition product and consistent with a prior literature [ 1 ]. Both impurities formed only under light exposure and were absent in the light-protected samples, confirming their photodegradation origin rather than inherent impurities. Conclusion Both DP-1 and DP-2 are photo-induced degradants of brexpiprazole, rather than real impurities. These findings enhance understanding of brexpiprazole’s degradation chemistry and emphasize the need for light-protected sample preparation to prevent artifactual peaks in pharmaceutical analysis of brexpiprazole drug substance and its formulations.
研究领域:
药物化学
·
分析化学
·
药物稳定性
·
杂质谱分析
·
质谱分析
·
核磁共振（NMR）
✓ 已验证
产品关联
DOI
高影响因子
DALTON TRANSACTIONS
·
2022
·Vol. 51
·期 32
·12352-12361
·
IF 4.569
Hongqiang Cui,Yongze Cao,Yuhang Zhang,Lei Li,Guojian Li,Sai Xu,Yichao Wang,Jinsu Zhang,Baojiu Chen
A series of Er3+/Yb3+ co-doped Cs3BiSr(P2O7)2 (CBSPO) phosphors with significant thermal enhancement were successfully prepared using the solid-state method and the thermal-enhancing effect was studied in detail. When the temperature increased from 303 to 723 K, the upconversion luminescence (UCL) emission intensities of 2H11/2 → 4I15/2 and 2H11/2 + 4S3/2 → 4I15/2 of Er3+ in CBSPO:0.1Er3+/0.2Yb3+ were enhanced 22.81 and 10.06 times under 980 nm laser excitation, respectively. Meanwhile, the UCL color of the sample obviously changed from orange to green with the increase in temperature. Furthermore, the UCL thermal enhancement mechanism was demonstrated, which originates from phonon-assisted transitions. In addition, the maximum absolute temperature sensitivity for CBSPO:0.1Er3+/0.2Yb3+ was calculated to be 0.01026 K−1 at 563 K via luminescence intensity ratio (LIR) technology. All the results show that the CBSPO:Er3+/Yb3+ phosphors can be used for safety warning and temperature measurement at high temperatures.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）