Nondestructive Testing and Evaluation
·
2026
·
IF 4.3
Fuxu Hou,Ping Huang,Hao Cui,Min Zhang,Xiujuan Qu,Jian Yao,Wei Zhang,Ming Liang,Jiachen Su,Zhefu Ma,Yue Wang,Yang Liu,Shi Bai
In this study, we propose a multi-stage all-liquid-phase magnetically responsive immunoassay based on bio-functionalised superparamagnetic nanoparticles, with the aim of achieving highly sensitive detection of small-molecule proteins (eg myoglobin and troponin) in whole blood/serum. The proposed method enables the specific capture of target biomarkers via a dual-target sandwich strategy, with a biotin–streptavidin amplification system incorporated to enhance the reaction signal. Meanwhile, harnessing the interlayer effects of the multi-stage reagents effectively suppresses non-specific background interference, thereby reducing noise and enhancing detection sensitivity. In this work, myoglobin (MYO) was selected as the model analyte, and a series of concentrations were prepared in both PBT buffer and horse serum matrices for methodological validation. Experimental results show that, in both serum-free and serum-containing environments, the proposed method demonstrates excellent detection sensitivity for MYO at concentrations as low as 0.1 ng/mL, coupled with a linear range spanning a 1,000-fold concentration interval and requiring only 15 min for the entire assay. The experimental results demonstrate the efficacy of the proposed method, highlighting its high stability and excellent resistance to background noises. These findings underscore its strong potential for clinical application.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2020
·
IF 2.369
Yaqi Ding,Neng Gao,Yongping Wu,Yongmei Xuan,Guangming Chen
Calcium chloride (CaCl2) aqueous solution as a liquid desiccant has the disadvantage of low vapor pressure and easy crystallization. Ionic liquids (ILs) such as [Emim]Cl, [Emim]Ac, and [Emim]Br have been verified to have a good ability to reduce the vapor pressure. In this paper, the vapor pressures of four kinds of CaCl2 + ILs + H2O were measured, which were CaCl2 + [Emim]Br + H2O (mass ratio CaCl2/[Emim]Br = 2:1) at temperatures of between 311.10 and 394.45 K, CaCl2 + [Emim]Cl + H2O (mass ratio CaCl2/[Emim]Cl = 2:1) at temperatures of between 306.58 and 393.89 K, CaCl2 + [Emim]Ac + H2O (mass ratio CaCl2/[Emim]Ac = 2:1) at temperatures of between 304.93 and 382.71 K, and CaCl2 + [Emim]NO3 + H2O (mass ratio CaCl2/[Emim]NO3 = 2:1) at temperatures of between 312.46 and 391.80 K, with the mass fraction of solute ranging from 0.2 to 0.5. The Antonie-type equation was used to fit the measured results. The average absolute relative deviation (AARD %) values of the measured vapor pressures and calculated vapor pressures were 0.52, 0.40, 0.33, and 0.27%, which showed good consistency and accuracy. Comparing the vapor pressures of the different solutions at the same concentration, the following order of the four anions with the ability to reduce the vapor pressure of CaCl2 + H2O can be drawn at a mass fraction of 0.4: Br– > Cl– > NO3– > Ac–.
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APPLIED CATALYSIS A-GENERAL
·
2020
·
IF 5.006
Jingjie Luo,Enhui Qu,Yixue Zhou,Yanan Dong,Changhai Liang
Rhenium , although viewed as one of the noble metals with lower-price, has been commonly used as doping element in the bimetallic catalysts due to its middlebrow to activate hydrogen. Its major role as catalyst is less frequently mentioned. In this work, rhenium has been decorated on the surface of activated carbon and used for the selective hydrogenation of dimethyl 1, 4-cyclohexanedicarboxylate (DMCD) to 1, 4-cyclohexanedimethanol (CHDM). Characterizations suggested that ReO x particles were anchored occupying the surface oxygenated groups on pre-functionalized carbon. Rhenium decoration modified both the textural and chemical properties of the samples. Electrons were easily transferred from Re to the neighboring C atoms as a result of the formation of fine ReO x particles. Medium strong acid sites were generated and rhenium species in the reduced states could be still maintained under appropriate rhenium dispersion. The moderate hydrogenation ability of rhenium catalyst partially restrained the excessive hydrogenation of CHDM to other by-products. Rational decoration of 5 wt% Re performed the better catalytic performance with complete conversion of diester and 66 % yield of diol. The specific rate reached 9.5 × 10 2 m m o l D M C D ∙ g R e - 1 ∙ h - 1 at 220 °C under 10 MPa H 2 .
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BIORESOURCE TECHNOLOGY
·
2020
·
IF 7.539
Zhe Dou,Guochao Xu,Ye Ni
A novel carboxylesterase Ac Est1 was identified from Acinetobacter sp. JNU9335 with high efficiency in the biosynthesis of chiral precursor of Edoxaban through kinetic resolution of methyl 3-cyclohexene-1-carboxylate (CHCM). Sequence analysis revealed Ac Est1 belongs to family IV of esterolytic enzymes and exhibits <40% identities with known carboxylesterases. The optimum pH and temperature of recombinant Ac Est1 are 8.0 and 40 °C. Substrate spectrum analysis indicated that Ac Est1 prefers substrates with short acyl and alcohol groups. Ac Est1 was highly active in the hydrolysis of CHCM with k cat of 1153 s −1 and displayed high substrate tolerance. As much as 2.0 M (280 g·L −1 ) CHCM could be enantioselectively hydrolyzed into ( S )-CHCM by merely 0.08 g·L −1 Ac Est1 with ee s of >99% ( S ) and substrate to catalyst ratio (S/C) of 3500 g·g −1 . These results indicate that the novel Ac Est1 is a promising biocatalyst in the synthesis of chiral carboxylic acids.
研究领域:
生物催化
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酶学
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药物化学
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高影响因子
JOURNAL OF FOOD SCIENCE
·
2025
·Vol. 90
·期 8
·e70445
·
IF 3.4
Jiahui Du,Yifeng Wu,Jiushi Guo,Jie Cao,Tao Sun,Tungalag Dong,Yuming Deng,Xing Wang,Xueyan Yun
The quality of yogurt deteriorates during storage due to exposure to oxygen and UV light, and high-barrier packaging effectively mitigates this issue. Concurrently, there is increasing interest in replacing petroleum-based packaging with eco-friendly alternatives. In this study, poly(lactic acid-butylene itaconate) (PLBI), developed as a modified version of poly (L-lactic acid) (PLLA) to enhance toughness, was combined with poly (vinyl alcohol) grafted with acryloyl chloride (PVA-g-AC) through UV curing. The resulting PLBI/PVA-g-AC films exhibited significantly improved barrier properties. They were used to package stirred yogurt alongside polyethylene/nylon (PE/NY) films for comparison. Quality assessments, including acidity, water-holding capacity, and viable bacterial counts, demonstrated that PLBI/PVA-g-AC films provided superior preservation. Metabolomics analysis revealed increased flavor compounds, such as acids and alcohols, and decreased sugar levels in these packaged yogurt. This work expands potential applications of PLLA-based materials in food packaging and offers insights into the influence of oxygen on yogurt storage quality.
研究领域:
食品包装
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高分子科学
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食品科学
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材料科学
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可降解材料
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乳品技术
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代谢组学
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Shu-Ting Cheng,Jia-Xin Song,Xiao-Fang Shen,Yue-Hong Pang
Dimethyl phthalate (DMP) is widely used as a plasticizer in the plastics industry, posing a serious threat to environmental pollution and public health. In this work, CuFe 2 O 4 @AC was used as a coating to prepare a novel solid-phase microextraction (SPME) fiber. CuFe 2 O 4 @AC fiber exhibits a larger specific surface area and more active sites, significantly enhancing DMP enrichment efficiency. The SPME method was applied for DMP measurement in beverages. Under optimal conditions, the developed method demonstrates a low detection limit (0.07 ng mL −1 ), a wide linear range (0.5–1000 ng mL −1 ), and good repeatability. Subsequently, SPME method combined with electro-Fenton degradation was established. The degradation process of DMP was dynamically analyzed by combining DFT calculation with gas chromatography–mass spectrometry. We developed a dynamic analytical method for extracting and monitoring electro-Fenton degradation products. This approach demonstrates significant potential for monitoring the degradation process of trace environmental endocrine disruptors.
研究领域:
环境化学
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分析化学
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材料科学
·
化学工程
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Journal of the Taiwan Institute of Chemical Engineers
·
2026
·
IF 6.9
Wenjian Liu,Xiao Cheng,Yuchen Jiang,Mengjiao Fan,Shu Zhang,Shuang Wang,Xun Hu
Background The performance of activated carbon (AC) is dependent on its pore structure. However, activation processes involving agents like K 2 C 2 O 4 can lead to significant carbon loss and reduced yield due to vigorous cracking reactions. To address this, the present study employed impregnation of the biomass feedstock with a formic acid lignin solution prior to activation. This approach aims to leverage the protective function of lignin to suppress cracking, enhance product yield, and investigate its regulatory mechanism on the structure of the resulting AC. Methods The method involves impregnating the cellulose and peach wood feedstocks with a formic acid-lignin solution. Subsequently, the impregnated materials undergo chemical activation using either ZnCl 2 or K 2 C 2 O 4 as the activating agent. Significant findings The results showed that lignin impregnation prior to activation enhanced the mass yield of AC compared to direct activation without lignin (76.9% versus 71.4%), because lignin serves as a precursor for stabilizing carbon structure formation. AC from ZnCl 2 activation generally exhibited higher specific surface areas (1655 m 2 g –1 versus 1226 m 2 g –1 via K 2 C 2 O 4 activation), while K 2 C 2 O 4 promoted severe carbon cracking but favored the formation of heavy organics in bio-oil. However, lignin impregnation reduced the specific surface area, possibly due to the formation of a protective layer that hindered activating agent penetration and interaction with the feedstock components (1655 m 2 g –1 versus 1308 m 2 g –1 via ZnCl 2 activation of lignin-impregnated precursor). AC obtained through ZnCl 2 activation exhibited a favorable adsorption ability for tetracycline, and all prepared ACs demonstrated exceptional removal efficiency for basic fuchsin due to its well-developed porosity. In addition, impregnation with lignin introduced more oxygen-containing functional groups, such as -OH and C O, onto the AC, significantly enhancing its surface hydrophilicity. Overall, this study provides a practical strategy for tailoring the yield, pore structure, and surface properties of biomass-derived AC for targeted environmental remediation.
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FUEL
·
2022
·
IF 8.035
Jun Liu,Yu Zhang,Zhoujie Liang,Guojie Zhang,Ying Wang,Yuqing Zhao,Guoqiang Li,Yongkang Lv
In this paper, a series of bimetallic catalysts with different Ni/Co ratios were prepared by co-impregnation method for application in methane dry reforming reaction. The effects of different Ni/Co ratios on the catalyst performance were investigated. The catalysts were characterized by XRD, BET, H 2 -TPR, TG, TEM and FTIR. The results showed that after the introduction of a certain amount of Co, the synergistic effect between Ni and Co enhanced the active component-carrier interaction, thus improving the dispersion of the active component of the catalyst, reducing the particle size of the metal, and increasing the activity of the catalyst. Meanwhile, the mechanistic study showed that the introduction of Co species with strong oxygen affinity facilitated the formation of oxygen vacancies. It makes the catalysts contain higher lattice oxygen and carbonate species, which was conducive to the elimination of carbon accumulation, thus improving the stability of catalysts. Therefore, the 10Ni-8Co-10Y/WC-AC catalyst exhibited excellent dry reforming of methane (DRM) performance at a Ni/Co ratio of 5:4. The conversions of CO 2 and CH 4 were 95 % and 88 % at 800 °C under atmospheric pressure, respectively.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2019
·
IF 4.084
Yinghui Sun,Guojie Zhang,Ying Xu,Riguang Zhang
The catalytic activity of DRM reaction over 1M-1Co-1Ce/AC-N (M = Ca and Mg) catalysts was investigated at 800 °C and under atmospheric pressure. By promoting N-doped activated carbon supported Co-Ce catalysts with alkaline-earth metals to obtain catalysts with better catalytic performance is the main purpose of study. The catalysts were prepared by wet-impregnation method and the influence of impregnation sequence on catalytic performance was also studied. The characterization was conducted using TPR, TPD , XPS, TEM and Raman. The catalyst 1Ca-1Co-1Ce/AC-N promoted with Ca and prepared by co-impregnation exhibited higher catalytic activity than unmodified. This was mainly due to the stronger interaction between metal and support as well as better active metals dispersion. The 1Ca-1Co-1Ce/AC-N catalysts also displayed excellent stability and XPS results indicated that higher Ce 3+ /Ce 4+ and O β /(O α +O β ) ratios were observed on this catalyst. However, the catalyst 1Co-1Ce/1Ca/AC-N prepared with sequential impregnation exhibited poor stability. In addition, the TEM of the spent catalysts revealed that there were a large number of carbons were generated on active metal surface.
研究领域:
催化化学
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能源化学
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材料化学
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环境化学
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化学工程
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MOLECULES
·
2023
·Vol. 28
·期 12
·4830
·
IF 4.6
Xiaorui Yang,Xiaotong Li,Jing Zhao,Jinhua Liang,Jianliang Zhu
Sorbitol, a product primarily derived from glucose hydrogenation, has extensive applications in the pharmaceutical, chemical and other industries. Amino styrene-co-maleic anhydride polymer encapsulated on activated carbon (Ru/ASMA@AC) catalysts were developed for efficient glucose hydrogenation and were prepared and confined Ru by coordination with styrene-co-maleic anhydride polymer (ASMA). Through single-factor experiments, optimal conditions were determined to be 2.5 wt.% ruthenium loading and a catalyst usage of 1.5 g, 20% glucose solution at 130 °C, reaction pressure of 4.0 MPa, and a stirring speed of 600 rpm for 3 h. These conditions achieved a high glucose conversion rate of 99.68% and a sorbitol selectivity of 93.04%. Reaction kinetics testing proved that the hydrogenation of glucose catalyzed by Ru/ASMA@AC was a first-order reaction, with a reaction activation energy of 73.04 kJ/mol. Furthermore, the catalytic performance of the Ru/ASMA@AC and Ru/AC catalysts for glucose hydrogenation were compared and characterized by various detection methods. The Ru/ASMA@AC catalyst exhibited excellent stability after five cycles, whereas the traditional Ru/AC catalyst suffered from a 10% decrease in sorbitol yield after three cycles. These results suggest that the Ru/ASMA@AC catalyst is a more promising candidate for high-concentration glucose hydrogenation due to its high catalytic performance and superior stability.Keywords:Ru/ASMA@AC catalyst;coordination;glucose conversion;sorbitol yield;confine
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Chengpan Lei,Xiaobin Zhang,Zhikang Rao,Shenghui Chen,Siqi Dong,Hanyang Bao,Ying Xu
An electrochemical impedance detection method based on 3-aminophenylboronic acid-modified magnetic nanoparticles (M-APBA) is proposed, with machine learning models employed to facilitate high-sensitivity and high-accuracy glucose detection in complex biological samples. By leveraging the specific binding affinity between synthesized M-APBA nanoparticles and glucose, detection sensitivity and anti-interference capability were significantly enhanced. Experimental results demonstrated a well-defined linear response for glucose concentrations ranging from 1 to 50 μmol L −1 , with a detection limit as low as 0.71 μmol L −1 . Multidimensional impedance spectral features were extracted using the Randles equivalent circuit model, and the prediction accuracy of glucose concentration in real sample was significantly improved by incorporating an XGBoost model optimized via grid search method. The model achieved an R 2 value of 0.9997, with mean absolute error (MAE) and root mean square error (RMSE) reduced to 0.1068 and 0.2321, respectively. Compared with traditional single-feature fitting methods (the Rct value), the proposed multi-feature fusion approach demonstrated superior detection accuracy and stability in complex biological samples. Furthermore, measurements conducted on real samples revealed that M-APBA nanoparticle-modified electrodes maintained excellent detection performance in complex environments, exhibiting high repeatability and strong anti-interference capability. This study proposes a non-enzymatic glucose detection strategy by integrating M-APBA-modified magnetic nanoparticles with a machine learning-based impedance analysis framework, offering a novel solution for non-invasive, real-time glucose monitoring and demonstrating great potential for application in portable, low-cost wearable detection devices.
研究领域:
电化学传感器
·
纳米技术
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生物医学工程
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机器学习
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分析化学
·
可穿戴设备
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高影响因子
Materials Today Chemistry
·
2023
·
IF 7.3
J.P. Mwizerwa,K. Xu,C. Liu,N. Zhao,Y. Li,P. Ndagijimana,Z. Chen,J. Shen
Currently, the development of high-performance lithium-ion batteries (LIBs) with improved areal capacity is still challenging. The common strategy to improve areal capacity is to increase the thickness of electrode materials. However, the application of thick electrodes remains challenge due to poor mechanical properties , slow charge and ion transport, and poor electrolyte infiltration . In this study, thick electrodes are constructed by 3D printing a Li 4 Ti 5 O 12 @VSe 2 -based ink. The highly electrical conductor VSe 2 on the Li 4 Ti 5 O 12 surface improves the ion and charge transport and eases the internal resistance of the 3D-printed electrode during charge and discharge. As a result, LIBs employing these thick electrodes show a high-rate capability of 128.9 mAh/g at 10 C, improved areal capacities up to 6.2 mAh/cm 2 , and ultrastable cycling capability (84.5% of capacity retention after 1700 cycles). Moreover, full cells utilizing 3D-Li 4 Ti 5 O 12 @VSe 2 as the anode and 3D-LiFePO 4 @AC/rGO as the cathode with 1.81 V potential yield a high specific capacity of 152.5 mAh/g at 0.1C, a high specific energy density of 276.025 Wh/kg, and a power density of 30.5 W/kg at 0.1C. This work paves the way to designing thick electrodes for high-performance LIBs.
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危险品化学品经营许可证（带存储）