Materials Research Express
·
2022
·Vol. 9
·期 9
·095001
·
IF 2.025
Wanshu Yan,Pingping Hu,Yiguo Jiang,Xiuquan Xu,Xianfeng Ma,Mengru Wang,Xinyue Bao
Photocatalytic inactivation has been proved to be an effective strategy to eliminate pathogenic bacteria in water. Herein, a novel 0D/2D p-n heterojunction of Ag2S-anchored P-doped g-C3N4 (Ag2S/PCN) were constructed by a simple two-step process coupling one-pot calcination and ultrasonic-assisted synthesis. The photocatalytic performance of as-prepared Ag2S/PCN composites was investigated by inactivating multidrug-resistant E. coli under visible light irradiation. The results indicated that Ag2S/PCN-5 possessed outstanding photocatalytic inactivation activity and superior stability, which could completely inactivate 7.0 log E. coli cells within 60 min. The enhanced photocatalytic activity of Ag2S/PCN-5 was mainly attributed to the elevated visible-light response and improved production and transfer of photoexcited charges. In addition, the free radicals trapping experiments results revealed that h+ and •O2− were predominantly responsible for the efficient inactivation activity. Finally, according to the 0D/2D structure and energy band configuration analysis, the enhanced p-n type heterojunction photocatalytic inactivation mechanism of Ag2S/PCN was discussed in detail.
研究领域:
环境科学
·
微生物学
·
材料科学
✓ 已验证
DOI
高影响因子
International Journal of Applied Mechanics
·
2024
·
IF 2.9
Shahao Li,Yang Chen,Xiaofeng Li,Hongyan Yang,Mengze Lu,Wei Zhang,Chuanxia Jiang,Shuming Cui,Junkai Liang,Liqun Tang,Taolin Sun
Recently, vitrimers with a reversible N → B coordination dynamic structure have garnered interest not only for their self-healing and reprocessable properties but also for their hydrolytic stability. Reported vitrimers with N → B internal coordination dynamic structure were excessively rigid, limiting their stretchability and toughness. This study synthesized a cross-linking agent (DNCB) with a cyclic nitrogen-boron coordination structure. This agent was then used in copolymerization with n-butyl acrylate (BA) and 4-vinylphenylboronic acid (BOH) to create soft vitrimers. By systematically tuning the composition, soft vitrimers exhibit water resistance along with high viscoelasticity, stretchability, toughness, and adhesive properties against various substrates. The observed mechanical behavior is attributed to the rapid relaxation of N → B coordination bonds and slow relaxation of B-O bonds in boroxine within the polymer network. It is anticipated that these soft vitrimers will be applied in adhesives, flexible electronics, and soft robotics due to their favorable properties.
研究领域:
材料科学
·
高分子化学
·
软物质物理
·
胶粘剂技术
·
柔性电子学
·
机器人学
✓ 已验证
DOI
高影响因子
Advanced Sustainable Systems
·
2022
·Vol. 6
·期 3
·2100380
·
IF 6.737
Zhengyi Li,Hu Li,Song Yang
Catalytic upgrading of CO 2 into value-added chemicals to build the excess carbon cycle is of great significance. In this work, carboxylate-functionalized zeolitic imidazolate framework (F-ZIF-90) with good crystallinity and porosity is constructed from ZIF-90 and employed as a robust heterogeneous catalyst to boost the reductive N -functionalization of various amines with CO 2 to furnish N -formyl compounds (up to 99% yield) in the presence of PhSiH 3 under an ambient environment. The imidazole carboxylate species ( COO - ) can not only activate hydrosilane and CO 2 to form the key intermediate formoxysliane but also activate amines to participate in the N -formylation reaction to obtain the target product. Moreover, it can enhance the catalyst capture and exchange ability toward ambient CO 2 . The powerful adsorption capacity of the F-ZIF-90 catalyst toward CO 2 is conducive to elevating CO 2 concentration around the active species. Theoretical calculations show that the carboxylate-mediated conversion path undergoes the transition state of hydrosilane activation with a relatively lower energy barrier (Δ G = 26.9 kcal mol –1 ). F-ZIF-90 exhibits good thermochemical stability with no obvious activity attenuation after repeated use 5 times. This strategy opens a new avenue based on ZIFs to develop heterogeneous catalysts for reductive upgrading of CO 2 .
研究领域:
催化
·
材料科学
·
化学工程
·
环境化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2020
·Vol. 31
·期 8
·1-9
·
IF 2.489
Li Wan,Hu Xueying,Chen Jiawei,Wei Zhengnan,Song Chengwu,Huang Rongzeng
The intrinsic fragility of hydroxyapatite (HAP) restricts its wider applications for local delivery of antibiotics. The composites formed by integrating HAP with hydrogels can improve the properties of HAP. However, these reported composites not only require tedious preparation and employ organic solvent and toxic reagents, but also hardly have inherent antimicrobial property. In this study, N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalanine/nano-hydroxyapatite (Fmoc-L-Phe/nHAP) hybrid supramolecular hydrogels with antibacterial property and cytocompatibility was prepared by integrating nHAP as reinforcement with Fmoc-L-Phe supramolecular hydrogels. The results showed that nHAP bounds in the chamber of the gel network and adheres to the fiber of Fmoc-L-Phe due to intermolecular interaction, remarkably improving the mechanical strength of Fmoc-L-Phe supramolecular hydrogels. The results of inhibition zone experiment and MTT experiment showed that the Fmoc-L-Phe/nHAP hybrid supramolecular hydrogels possess antimicrobial property and cytocompatibility. In vitro release experiment of chlorogenic acid (CGA) from the hybrid supramolecular hydrogels was performed. The study of the release kinetics indicated that the release behavior of CGA from the hybrid supramolecular hydrogels is following Weibull model and release mechanism involved Fickian diffusion and erosion of the surface of hydrogel matrix. The release of CGA shows a good inhibition effect on S. aureus . The results show that the Fmoc-L-Phe/nHAP hybrid hydrogels with antibacterial property and cytocompatibility have promising applications as drug delivery carrier.
Due to the intrinsic fragility of hydroxyapatite (HAP), the properties of HAP could be improved by incorporation into hydrogels. However, these reported composites not only require tedious preparation and employ organic solvent and toxic reagents, but also hardly have inherent antimicrobial property. We prepared N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalanine/nano-hydroxyapatite (Fmoc-L-Phe/nHAP) hybrid supramolecular hydrogels by integrating nHAP as reinforcement with Fmoc-L-Phe supramolecular hydrogels. The results showed that nHAP bounds in the chamber of the gel network and adheres to the fiber of Fmoc-L-Phe due to intermolecular interaction, remarkably improving the mechanical strength of Fmoc-L-Phe supramolecular hydrogels. The results of inhibition zone experiment and MTT experiment showed that the Fmoc-L-Phe/nHAP hybrid supramolecular hydrogels possess antibacterial property and cytocompatibility. In vitro release experiment of chlorogenic acid (CGA) from the hybrid supramolecular hydrogels was performed. The study of the release kinetics indicated that the release behavior of CGA from the hybrid supramolecular hydrogels is following Weibull model and release mechanism involved Fickian diffusion and erosion of the surface of hydrogel matrix. The release of CGA shows a good inhibition effect on S. aureus . The results show that the Fmoc-L-Phe/nHAP hybrid hydrogels with antibacterial property and cytocompatibility have promising applications as drug delivery carrier.
研究领域:
材料科学
·
生物医学工程
·
药学
✓ 已验证
DOI
高影响因子
TETRAHEDRON-ASYMMETRY
·
2010
·
IF 2.625
Zhen-Wei Zhang,Gui Lu,Miao-Miao Chen,Ning Lin,Yong-Bo Li,Tamio Hayashi,Albert S.C. Chan
The first asymmetric Mannich-type reaction of methyl isocyanoacetate with N -sulfonylimines catalyzed by cinchona alkaloid derivatives yielded 2-imidazolines with high diastereoselectivities and good enantioselectivities (up to >99:1 dr and 70% ee). This reaction provided a convenient route to access various substituted 2-imidazoline-4-carboxylates and related α,β-diamino acids in high enantiomeric purities.
研究领域:
有机化学
·
药物化学
·
不对称合成
·
催化化学
·
生物有机化学
✓ 已验证
DOI
高影响因子
Small
·
2024
·Vol. 20
·期 32
·2312003
·
IF 13
Mohammad Nisar,Adeel Abbas,Junze Zhang,Fu Li,Zhuanghao Zheng,Guangxing Liang,Ping Fan,Yue-Xing Chen
Enhancing the thermoelectric performance of n-type polycrystalline SnSe is essential, addressing challenges posed by elevated thermal conductivity and compromised power factor inherent in its intrinsic p-type characteristics. This investigation utilized solid-state reactions and spark plasma sintering techniques for the synthesis of n-type SnSe. A significant improvement in the figure of merit (ZT) is achieved through strategic reduction in Se concentration and optimization of crystal orientation. The co-doping with Br and Ge further improves the material; Br amplifies carrier concentration, enhancing electrical conductivity, while Ge introduces effective phonon scattering centers. In the Br/Ge co-doped SnSe sample, thermal conductivity dropped to 0.38 Wm⁻¹K⁻¹, yielding a remarkable power factor of 662 µW mK − 2 at 773 K, culminating in a ZT of 1.34. This signifies a noteworthy 605% improvement over the pristine sample, underscoring the pivotal role of Ge doping in enhancing n-type material thermoelectric properties. The enhancement is attributed to Br doping introducing additional electronic states near the valence band, and Ge doping modifying the band structure, fostering resonant states near the conduction band. The Br/Ge co-doping further transforms the band structure, influencing electrical conductivity, Seebeck coefficient, and thermal conductivity, advancing the understanding and application of n-type SnSe materials for superior thermoelectric performance.
研究领域:
材料科学
·
热电材料
·
固体物理
·
凝聚态物理
✓ 已验证
DOI
高影响因子
JOURNAL OF RARE EARTHS
·
2024
·
IF 5.2
Hao Qin,Hui Wan,Guofeng Guan
Hydroisomerization of n-alkanes plays an important role in fuel and lubricants processing. Bifunctional catalysts with ultralow platinum loading have recently been reported successively for hydroisomerisation. Herein, the catalysts were prepared successfully with different methods to improve the catalytic performance. The conversion of 0.01%Pt1@CeOx/SAPO-11 prepared by co-calcination method (0.01%Pt1@CS-c) is 71.4%, 25% higher than the other prepared by precipitation method. The turnover frequency per active surface platinum site (TOFPt) of 0.01%Pt1@CS-c is as high as 13115 h –1 . Revealed by the X-ray photoelectron spectroscopy (XPS) results, the quality of phase boundary/intersurface between ceria and zeolite is found significantly different. The conjunction quality of phase boundary directly affects the spillover rate of intermediate species, which further leads to an apparent activity difference. In addition, the possible role of ceria in the reaction is discussed, rather than just as a carrier for the active metal atoms.
研究领域:
催化化学
·
能源材料科学
✓ 已验证
DOI
高影响因子
iScience
·
2022
·
IF 6.107
Kefeng Wang,Qingzhen Yu,Wenli Mao,Yuxin Zheng,Jing Xu,Yukun Wang
Vinylboron compounds are important compounds in organic chemistry and biology. In this communication, we developed a copper(I)-catalyzed, highly regio- and stereoselective radical trans -hydroboration of ynamides with N -heterocyclic carbene (NHC)-ligated borane is reported, which leads to a series of trans -boryl enmides that can be conveniently transformed into various multi-substituted enamides. Further investigation showcased that our method is robust and scalable. The mechanism of this unique reaction is studied and discussed.
研究领域:
有机化学
·
合成化学
✓ 已验证
DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 35
·29638-29645
·
IF 3.289
Xin Ge,Xinzhi Chen,Chao Qian,Shaodong Zhou
Ullmann type C–N coupling reaction catalyzed by copper(I) with D-glucosamine derivatives as promoters was studied by means of combined experimental/theoretical investigation. The catalytic role of D-glucosamine was addressed. In contrast with previous speculations, the amino group may not count in the catalytic cycle in which the oxidative addition/reductive elimination mechanism works. Experimental results are in good agreement with theoretical findings. Extensive work indicates the wide applicability of the C–N coupling strategy exploited in this work.
研究领域:
有机化学
·
催化化学
·
药物化学
·
计算化学
·
合成方法学
·
生物正交化学
·
金属有机化学
✓ 已验证
DOI
高影响因子
JOURNAL OF BIOMATERIALS APPLICATIONS
·
2024
·
IF 2.3
Dandan Niu,Danyang Zhou,Mengke Zhan,Lijing Lei,Jinhua Zhu,Xiuhua Liu
γ-Cyclodextrin-based metal-organic frameworks (γ-CD-MOF) were successfully synthesized using the solvent diffusion method and applied as carriers for trans-N-p-coumaroyltyramine (N-p-t-CT, NCT) to study the solubability, stability, sustained release and inhibitory activity against α-glucosidase. The solubilization effect of γ-CD-MOF on N-p-t-CT was performed using impregnation (NCT@CD-MOF-1) and co-crystallization (NCT@CD-MOF-2) methods. X-ray diffraction, scanning electron microscope (SEM), fourier transform infrared spectrometer (FTIR), and N2 adsorption/desorption were used to characterize the MOFs before and after loading NCT. The results showed that NCT@CD-MOF-2 had a better solubability for N-p-t-CT, 145.03 μg/mg of drug loading capacity could be achieved, and the solubility of NCT@CD-MOF-2 in water was 366 times higher than free N-p-t-CT. In addition, the stabilities of N-p-t-CT under temperature, UV light and pH conditions were greatly improved after encapsulation in γ-CD-MOF. Furthermore, NCT@CD-MOFs had a sustained release of N-p-t-CT over an extended period in vitro due to the primary encapsulation in pore structures. Notably, γ-CD-MOF loaded with N-p-t-CT showed superior inhibitory activity against α-glucosidase compared to free N-p-t-CT. Cytotoxicity studies demonstrated that NCT@CD-MOF-2 had low toxicity in vitro and perfect biocompatibility with HL-7702 cells, and γ-CD-MOF could reduce the toxicity of free N-p-t-CT at higher concentrations.
研究领域:
药剂学
·
生物化学
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Yuezhen Mao,Rongna Chen,Huanhuan You,Yang Liu,Sunrui Luan,Li Hou,Faming Gao
Antimony-based anodes possessing advantages of stable operating voltage and high theoretical capacity can replace graphene as alloy-based electrodes material in LIBs applications. However, the problems of capacity decaying and poor stability of Sb-based materials due to volume expansion and structural crushing during the long-term cycling remain to be solved. Therefore, we propose a strategy of using S and N co-doped carbon nanofibers encapsulated with Sb nanoparticles to overcome the above problems. The proposed material exhibits an excellent lithium storage performance with a high reversible specific capacity of 734 mAh g −1 at 0.1 A g −1 after 50 cycles (474.8 mAh g −1 at 1 A g −1 after 800 cycles, 394.5 mAh g −1 at 2 A g −1 after 2000 cycles). Importantly, a specific capacity of 288.5 mAh g −1 remains after more than 5000 cycles. The superior electrochemical performance of the S and N co-doped electrode is attributed to the proven structure and stability of the carbon matrix alleviating the volume changes of Sb during the process of lithium intercalation and extraction. The alloying/de-alloying reactions of the S@Sb@N-CNFs composite in the first charging/discharging process were systematically investigated by ex-situ XRD . This strategy of S and N co-doped carbon matrix could establish Sb-based materials as potential high-performance anodes for LIBs.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Shaohua Peng,Wenshuang Xu,Hui Liu
Stimuli-responsive hydrogels could effectively solve the problem that traditional drug carriers were difficult to deliver drug on-demand. However, some shortcomings such as complex preparation, single responsiveness, and narrow application still needed to be urgently overcome. In view of this situation, two kinds of hydrogels were elaborately designed in this work. In the unique ethanol/water mixed solvent , a homogeneous reaction system consisting of methacrylic acid (MAA) and N-isopropylacrylamide (NIPAM) was constructed, and a dual-responsive P(MAA-co-NIPAM) hydrogel was successfully synthesized. A near-infrared (NIR) responsive multi-functional PPy/P(MAA-co-NIPAM) hydrogel was subsequently prepared by the introduction of polypyrrole (PPy) via in-situ polymerization. NIR-responsive swelling, photodeformable, and photothermal ability of the hydrogel under NIR light irradiation were explored. It was found that rapid shape and temperature change could be achieved within 60 s for PPy/P(MAA-co-NIPAM) hydrogel. With doxorubicin as a model drug, the drug loading and in vitro controlled releasing behaviors under different conditions were comprehensively investigated. It was confirmed that the multi-responsive hydrogels had controllable drug releasing ability under different stimulations, which would realize potential targeted drug delivery in physiological environment. This work might provide a new synthetic method of hydrogel for drug releasing, which was expected to expand the potential application domain of hydrogel materials in NIR penetration targeted therapy.
研究领域:
药学
·
材料科学
·
生物医学工程
·
高分子化学
·
控制药物递送
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）