FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Chan Li,Xue Yang,Yunfei Zou,Li Zhang,Chuhuan Wei,Yan Ran,E. Zhao,Jibiao Yuan,Keshan Wang,Yongguo Jin,Ying Zhou,Qiujin Zhu,Yuxin Cheng,Yuanyuan Liu
Egg white gel (EWG) is a highly important raw and auxiliary material in food industry. With the increasing demand of consumers for nutrition, developing a modification method for regulating the texture of traditional egg white gel while enhancing its nutritional efficacy has become a challenge. Herein, a hierarchical W/O/W double emulsion filled gel was fabricated via a two-level emulsification process. The primary W/O emulsion, stabilized by synthesized γ-cyclodextrin metal-organic frameworks (CD-MOFs) Pickering emulsifiers, was incorporated into an egg white solution, where the endogenous emulsifying properties of the proteins facilitated the formation of the secondary O/W interface. The stability and morphology of the CD-MOFs-stabilized W/O emulsion (CDME) were analyzed, and the gel properties, molecular interactions, and microstructure of the W/O/W emulsion filled EWG gel (CDME-EWG) was then evaluated. The results indicated that CD-MOFs at 6 mg/mL (CDME-6) significantly enhanced the stability of the Pickering emulsion. This effect was achieved through the formation of a dense interfacial film at the oil/water boundary, which effectively promoted droplet dispersion and suppresses coalescence. Furthermore, the emulsion filled gel with 6 mg/mL CD-MOFs (CDME-EWG6) promoted the cross-linking within the gel network, leading to a more compact structure, enhanced water retention (52.84%) and hardness (887.00 g), as well as the enhancement in encapsulation capability (81.77%) and bioavailability (41.18%) of lutein. This study proposed a novel strategy for improving the performance of protein gels, which also provided the potential for co-encapsulation of multi-component bio-actives via the porous CD-MOFs and compartmentalized chamber within the W/O/W emulsion
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Haiyan Tian,Dong Xiang,Congfa Li
Herein, improvement of the stability of the water-in-oil-in-water (W/O/W) emulsions by addition of xanthan gum (XG)/locust bean gum (LBG) mixture in the inner water phase was aimed. The impact of XG/LBG mixture on the physical stability, microstructure and rheological properties of W/O/W emulsions was investigated. It was found that, compared with the control emulsions, the presence of XG/LBG mixture could improve the stability of W/O/W emulsions against coalescence. The tea polyphenols (TPPs) and XG/LBG mixture were simultaneously included in the internal aqueous phase of the double emulsion and stored at 25 and 40 °C in the dark for 28 d. The results showed that XG/LBG mixture not only had a protective role for TPPs encapsulated in the internal water phase, but also maintained more than 50% of the antioxidant capacity of TPPs.
研究领域:
食品科学
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胶体与表面化学
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材料科学
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Hongda Li,Honggao Deng,Shaonan Gu,Chenpu Li,Boran Tao,Shumin Chen,Xiong He,Guofu Wang,Wenfeng Zhang,Haixin Chang
The “FeMo cofactors” in biological nitrogenase play a decisive role in nitrogen reduction. Herein, a novel bionic Fe/Mo bimetallene was applied in photocatalytic nitrogen reduction. The surface coating Fe/Mo bimetallene of Bi 2 Mo 0.3 W 0.7 O 6 (BMWO) nanocrystals could effectively promote the separation and transportation of photogenerated carriers by multi–electron redox reactions and deliver 2.8 times longer photo–carrier lifetime. Consequently, the nitrogen fixation activity of Fe/Mo bimetallene–coated BMWO nanocrystal photocatalyst was obviously enhanced (218.93 μmol g –1 h −1 ), which was about 4.8 times that of unmodified BMWO nanocrystals. This work provides a novel approach to design bionic Fe/Mo bimetallene–modified inorganic semiconductor photocatalysts for nitrogen reduction.
研究领域:
材料科学
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催化化学
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环境科学
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高影响因子
Toxicology Research
·
2015
·Vol. 5
·期 1
·160-167
·
IF 3.983
Liye Zhu,Tao Yu,Xiaozhe Qi,Bo Yang,Lei Shi,Haoshu Luo,Xiaoyun He,Kunlun Huang,Wentao Xu
OTA can induce hepatotoxicity. Our previous research has shown that miRNAs play important roles in the OTA-induced hepatotoxicity. And miR-122 is the most abundant miRNA in the liver and is involved in diverse biological processes. This study was performed to clarify the role of miR-122 in OTA-induced hepatotoxicity. The expression levels of miR-122 and the target genes were quantified by real-time PCR. The OTA-induced apoptosis of hepatocyte and HepG2 cells was evaluated using a TUNEL kit, a CCK-8 kit, a flow cytometer and Hoechst 33342. miR-122 was inhibited in HepG2 cells. The results revealed that OTA affected rat hepatocyte apoptosis. miR-122 decreased at 4 weeks but increased at 13 weeks in the OTA-treated livers, and increased in the OTA-treated HepG2 cells; and the mRNA levels of CCNG1 and Bcl-w increased at 4 weeks and decreased at 13 weeks in the high-dose OTA-treatment groups and decreased in HepG2 cells. The apoptosis of HepG2 cells displayed a dose-related increase with OTA. However, the inhibition of miR-122 greatly reduced OTA-induced apoptosis. p53 decreased in vivo and in vitro. miR-122 is a primary effector of OTA-induced hepatocyte apoptosis through the CCNG1/p53 pathway and Bcl-w/caspase-3 pathway in vivo and in vitro. And miR-122 plays an important role in OTA-induced hepatotoxicity.
研究领域:
分子生物学
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毒理学
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细胞生物学
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PubMed
高影响因子
PLANT PHYSIOLOGY AND BIOCHEMISTRY
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2024
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IF 6.1
Mohsin Nawaz,Jianfan Sun,Samina Shabbir,Yanwen Bo,Feng He,Muhammad Mudassir Nazir,Farrukh Azeem,Muhammad Rizwan,Linxuan Pan,Guangqian Ren,Daolin Du
Cadmium (Cd) toxicity induces significant disruptions in growth and development, plants have developed strategies to alleviate metal toxicity promoting establishment even during herbivores infestation. The study demonstrates that W. trilobata maintains growth and development under the combined stress of Cd exposure and herbivore invasion by Spodoptera litura , in contrast to W. chinensis . Cd toxicity markedly reduce shoot elongation and total fresh biomass, and a significant decrease in the dry weight of the shoot biomass and leaf count by 19%, 18%, 16%, and 19% in W. trilobata compared to controls. An even more pronounced decrease of 35%, 43%, 45% and 43% was found in W. chinensis . Compared to W. chinensis, W. trilobata showed a higher increase in phytohormone production including abscisic acid (ABA), gibberellic acid (GA 3 ), indole-3-acetic acid (IAA) and methyl jasmonic acid (JA-me) under both Cd and herbivory stress as compared with respective controls. In addition, leaf ultra-structure also showed the highest damage to cell membranous structures by Cd-toxicity in W. chinensis . Furthermore, RNA-seq analysis revealed numerous genes viz., EMSY, MCCA, TIRI, BED-type, ABA, JAZ, CAB-6, CPSI, LHCII, CAX, HNM, ABC-Cd-trans and GBLP being differentially expressed between Cd-stress and herbivory groups in both W. trilobata and W. chinensis , with a particular emphasis on genes associated with metal transport and carbohydrate metabolism. Analyses employing the Gene Ontology (GO) system, the Clusters of Orthologous Groups (COG) categorization, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, highlight the functional and evolutionary relationships among the genes of the Phenylpropanoid and Flavonoid biosynthesis pathways and brassinosterod metabolism, associated with plant growth and development under Cd-toxicity and herbivory. W. trilobata opposite of W. chinensis , significantly improve plant growth and mitigates Cd toxicity through modulation of metabolic processes, and regulation of responsible genes, to sustain its growth under Cd and herbivory stress, which can be used in stress improvement in plants for sustainable ecosystem biodiversity and food security.
研究领域:
植物学
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植物生理学
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分子生物学
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基因组学
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环境科学
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DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2025
·
IF 3.8
Qiqiang Zhang,Lei Cao,Bo Peng,Hui Zhang,Xingyuan San,Yanchun Zhou,Man Jiang,Qingguo Feng,Chunfeng Hu
MAX phase ceramics, as a family of ternary layered ceramics, have received a lot of attention in the past decade due to their potential as precursors for two-dimensional transition metal carbides. However, due to complex multi-component metallurgical reactions, multicomponent MAX phase ceramics have always faced difficulties in purification and homogenization. This paper identifies a new strategy for synthesizing multicomponent MAX phase ceramics that can eliminate these synthesis difficulties. This path utilizes low-temperature (below 1000°C) stable Ti 2 AlC and carbide powder as initial materials to simplify complex multi-component reactions into a one-step reaction, successfully achieving high purity and precise doping ratio. As an example, four novel doped MAX phase ceramics, Ti 2 MAlC 2 (M = Nb, Ta, W) and Ti 2 HEAlC 2 (HE = 1/7Ti, 1/7V, 1/7Zr, 1/7Nb, 1/7Hf, 1/7Ta, 1/7 W) were successfully synthesized using this method. This dynamic-based design, on one hand, simplifies the reaction mechanism to make purification easier, and on the other hand, the concentrated release of entropy during the reaction process promotes phase transition and related element homogenization.
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高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Yi Li,Yiqiao Pei,Zuoyu Shan,Yumei Jiang,Steve W. Cui,Zouyan He,Ye Zhang,Hao Wang
Although various types of water-oil-water (W/O/W) double emulsions were explored and applied for intestine-targeted delivery, further research was needed to protect probiotics from the gastrointestinal barrier. Thus, this study aimed to encapsulate probiotics through a gel bead-bound emulsion system to improve the ability to resist the external environment, and sustained release of probiotics. In this study, sodium caseinate (NaCas)-κCarrageenan (κCar) by Maillard reaction was prepared as the external emulsifier. Then emulsions combined with sodium alginate (SA)-carboxymethyl chitosan (CMCS) hydrogel shells to encapsulate the internal aqueous phase of L . rhamnosus 76 ( LR76 ) for intestinal targeted delivery. The gel shell assembled with SA and CMCS in a citric acid solution was demonstrated by the combination of hydrogen bonding (protonated carboxyl –COOH and –OH) and electrostatic interactions (-COO - and –NH 3 + ) through IR spectroscopy. The system also showed excellent pH responsiveness and good thermal stability. The in vitro gastrointestinal simulated experiment showed the release of probiotics was managed through their swelling behavior with survival rate reaching 90.69 ± 0.04%. The slow-release properties of gel beads were also verified in vivo, which could be applicable in animals for further healthy effects. The 16S rRNA analysis revealed a high relative abundance of Lactobacillus from the Firmicutes, highest up to 88.08%. The above results suggested that the hydrogel bead system could be used as carriers for encapsulating probiotics, which provided a theoretical basis for the future application of probiotics in the food and pharmaceutical industries.
研究领域:
食品科学
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药学
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生物技术
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高影响因子
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
·
2022
·
IF 6.044
Shu Miao,Yunqiang Zhao,Zhuoming Xie,Longfei Zeng,Yan Lin
Ductilization and suppression of annealing-induced embrittlement have become the critical premises for various structural applications of high-strength tungsten materials but have yielded few practical advances. Here, we successfully fabricated W–Re and nano-particle doped W-Re-ZrC alloys with a combination of desirable ductility and a high tensile strength above 1.3 GPa by powder metallurgy plus hot swaging. Specifically, the W–Re and W-Re-ZrC alloys exhibit total elongations of 31.6% and 16.1%, respectively, at room temperature. Upon high-temperature annealing at 1600 °C, the W-Re-ZrC alloy still retains a high total elongation of 12.9% and a high tensile strength of over 1.3 GPa, unlike the W–Re alloy, which exhibits substantial losses of ductility and strength. Microstructure analysis reveals that a large amount of low-angle grain boundaries and high-density mobile dislocations are responsible for ductilization. Meanwhile, ZrC nano-particles stabilize low-angle grain boundaries and dislocation structures at elevated temperatures, suppressing annealing-induced embrittlement in the W-Re-ZrC alloy. The present work provides a promising methodology for manufacturing bulk high-strength tungsten materials with favorable room-temperature ductility and high resistance to catastrophic failure during long-term service.
研究领域:
材料科学
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冶金工程
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高影响因子
MACROMOLECULES
·
2010
·
IF 4.539
Keping Chen,Neil Grant,Liyun Liang,Haifei Zhang,Bien Tan
Amphiphilic block copolymers poly(ethylene glycol)-block-oligo(vinyl acetate) (PEG-b-OVAc) and OVAc-b-PEG-b-OVAc have been demonstrated to be effective surfactants for CO2-in-water (C/W) emulsions. However, the high cost and difficulty of synthesis process can render the economics of CO2 process unfavorable. In this work, by reversible addition−fragmentation chain transfer (RAFT) polymerization, a series of well-defined CO2-philic triblock copolymers X−OVAc-b-PEG-b-OVAc−X (where X stands for xanthate group) were synthesized. The structures and molecular weights of these copolymers were characterized by 1H NMR and GPC. The results of GPC analysis exhibited relatively narrow polydispersity (PDI < 1.35). The process of preparation of X−OVAc-based surfactants was much more simple, inexpensive and also easy to control, which could promote industrial-scale applications. The X−OVAc-based surfactants were found effectively to produce highly concentrated stable C/W emulsions. Porous emulsion-templated materials were prepared by the polymerization of the continuous phase of C/W emulsions. The open-cell morphology of the emulsion-templated materials was evidenced by scanning electron microscope. To tune the morphology of the porous structures, the influence of the surfactant concentration and molecular weight of OVAc block were also investigated. It was shown that X−OVAc-based surfactants can outperform perfluorinated surfactants and approach OVAc-based surfactants for such applications.
研究领域:
高分子化学
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材料科学
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表面活性剂化学
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DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Na Wu,Zhicheng Ye,Kangfu Zhou,Feifei Wang,Cheng Lian,Yazhuo Shang
Liquid crystal emulsion is a new type of emulsion, in which the emulsifier molecules are located at the oil/water (O/W) interface and form a long-range ordered and short-range disordered lamellar liquid crystal. The lamellar liquid crystal formed by the emulsifier is similar to the skin stratum corneum lipid structure, which enables it to have a broad application prospect in the fields of cosmetics, pharmaceuticals, etc. In this work, a liquid crystal nanoemulsion was obtained by passing a liquid crystal emulsion stabilized by hydrogenated lecithin and phytosterol combination through a microfluidizer. The microstructure of the prepared liquid crystal nanoemulsion was investigated experimentally by dynamic light scattering, transmission electron microscopy, and small-angle X-ray scattering. The results have shown that the nanoemulsion inherited the liquid crystal emulsion property, namely, the long-range ordered and short-range disordered lamellar structure still existed at the oil/water interface even though they underwent extrusion, friction, and acceleration. At the same time, the underlying mechanisms of the existence of lamellar liquid crystal between the oil phase and the water phase for the nanoemulsion were explored theoretically by molecular dynamics simulations. The simulation results elucidated that the hydrogenated lecithin and phytosterol combination improved the flexibility of the bilayer structure composed of emulsifiers. The bilayers were the basic structure units of lamellar liquid crystals, and thus, the improved flexibility of bilayers provided insurance for the existence of lamellar liquid crystals with larger curvature around the oil droplets. In addition, the applicable properties of liquid crystal nanoemulsion were studied, and the results have shown that the liquid crystal nanoemulsion presented better slow-release and moisturizing properties than traditional nanoemulsions due to the existence of multilayers between oil and water phases. This work not only provides necessary information for the development and effective application of liquid crystal emulsions but also is helpful for in-depth understanding the inner properties of lamellar liquid crystal at molecular level.
研究领域:
化妆品科学
·
药学
·
材料科学
·
分子动力学
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DOI
PubMed
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2019
·
IF 3.192
Tong Zhou,Jie Liu,Xinwen Zhang,Bin Shen,Jinlong Yang,Wenbin Hu,Lei Liu
The antibacterial properties of the microarc oxidation coating have gained wide attentions, and W-containing surface has been verified to be notably bactericidal. Herein, in this work, doping Na 2 WO 4 into the electrolyte to prepare the antibacterial W-containing microarc oxidation coating is proposed for the first time. No obvious crystal phase related to hexavalent W exists in the coating, and sodium tungstate may transform into a trace amount of tungsten oxides and amorphous substances. The sodium tungstate plays a crucial role in the antibacterial capability of the coating, the W-containing coating exhibits conspicuous bactericidal performance against both planktonic and adherent Escherichia coli and Staphylococcus aureus . The antibacterial mechanism of the W-containing coating is first revealed to be linked to the extracellular and intracellular reactive oxygen species (ROS). The W-containing dissolved matters spontaneously trigger the formation of the extracellular ROS, which directly destroy the bacterial cytoderm and cytomembrane. Meanwhile, the nanoscale W-containing dissolved matters penetrate the cell wall, and stimulate the generation of intracellular ROS which interact with the cytoplasmic components. Ultimately, the bacteria die from the cooperative effects of the extracellular and intracellular ROS.
研究领域:
材料科学
·
生物材料
·
表面工程
·
生物医学工程
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DOI
高影响因子
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS
·
2021
·
IF 3.871
S. Miao,Y. Lin,Y.Q. Zhao,Z.M. Xie
This work described an experimental investigation on the recrystallization behaviors of the hot-rolled particle strengthened W (PSW) material. Upon annealing, the three processes, that is, recovery, recrystallization and grain growth, proceed in a discontinuous fashion for our PSW material, and two or more processes could simultaneously occur in local regions. At an annealing temperature spanning from 1300 °C to 1500 °C, recovery is in the dominant position which is verified by deformed grains over half of the whole, accompanying with a gentle decrease in hardness. Meanwhile, recrystallization nucleation, primary recrystallization and abnormal grain growth is identified at 1300 °C, 1400 °C and 1500 °C, respectively. Further increasing the annealing temperature to 1600 °C and 1700 °C, normal grain growth takes precedence over recovery, along with a marked reduction in hardness. TEM observations show that owing to microstructural heterogeneity induced by particle dispersion, local regions have an advantage in terms of strain energy storage over other regions during hot rolling, enabling a preferential recrystallization nucleation at 1300 °C; whereas nanosized TiC particles are capable of inhibiting grain growth at elevated temperature, and thus retard the recrystallization rate. In addition, our as-rolled PSW material exhibits a different texture, and the dominant α-fiber of {100}〈011〉 and {112}〈1−10〉 transforms into γ-fiber texture of {111}〈011〉 and {111}〈−1−12〉 during recrystallization.
研究领域:
材料科学
·
金属学
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DOI
高影响因子
危险品化学品经营许可证（带存储）