FOOD CHEMISTRY
·
2024
·
IF 8.5
Mingsha Jie,Shengkai Lan,Bing Zhu,Amei Zhu,Xiaoyue Yue,Qisen Xiang,Yanhong Bai
Protecting human health and ensuring food security require the swift and accurate detection of sulfonamides (SAs) residues in foods. Herein, we proposed an Eu-postfunctionalized bimetallic porphyrin metal-organic framework (PCN-221(Zr/Ce)@Eu-DPA-H 4 btec) synthesized solvothermally for fluorescence sensing. The PCN-221(Zr/Ce)@Eu-DPA-H 4 btec fluorescent sensor demonstrated excellent stability and high selectivity to SAs, and the detection limits of sulfamethazine (SM 2 ), sulfamerazine (SMR), and sulfamethoxydiazine (SMD) were as low as 56 nmol/L, 45 nmol/L, and 56 nmol/L, respectively. The PCN-221(Zr/Ce)@Eu-DPA-H 4 btec fluorescent sensor was successfully applied for the detection of SM 2 , SMR, and SMD in real pork and milk samples, with satisfactory recoveries (81.2–118.3%) and high precisions (RSDs <8.2, n = 3). Combining the optical properties of the nanohybrids, PCN-221(Zr/Ce)@Eu-DPA-H 4 btec integrated fluorescent hydrogels were innovatively prepared for visual sensing of SM 2 , SMR, and SMD. This study provides an uncomplicated and sensitive method for SAs detection in food matrices.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2012
·
IF 2.159
Yan-Jing Gu,Bing Yan,Yan-Yan Li
Novel organic–inorganic mesoporous luminescent polymeric hybrid materials containing europium(III) complexes incorporated to mesoporous silica SBA-15/SBA-16 have been prepared by simple physical doping (impregnation) methods, followed by the addition polymerization reaction of the monomer 4-vinylpyridine (vpd) extending along the mesoporous channels. The precursor europium(III) complexes are synthesized by β-diketonate (β-diketonate=2-thenoyltrifluoroacetonate (tta), hexafluoroacetylacetonate (hfac), trifluoroacetylacetonate (taa)) and monomer 4-vinylpyridine (vpd) coordinated to Eu 3+ , and SBA-15/SBA-16 are obtained via a sol–gel process. After the physical doping and the polymerization reaction , the final ternary materials Eu(β-diketonate) 3 pvpd-SBA-15/Eu(β-diketonate) 3 pvpd-SBA-16 (β-diketonate=tta, hfac, taa) are received. The physical properties and espeically the photoluminescence of these hybrids are characterized, and the XRD and BET results reveal that all of these hybrid materials have uniformity in the mesostructure. The detailed luminescence investigation on all the materials show that Eu(tta) 3 pvpd-SBA-16 have the highest luminescence intensity and the materials with taa ligands have longer lifetimes.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF RARE EARTHS
·
2024
·
IF 5.2
Tianhao Xia,Yuwen Yuan,Yunpeng Wang,Pragati Awasthi,Wenkun Dong,Xvsheng Qiao,Dong Chen,Shisheng Ling,Xianping Fan
This study aims to advance the development of magnetic fluorescent polymer microspheres for biomedical detection applications. Conventionally, dopants have utilized europium(III) (Eu(III)) organic complexes due to their high compatibility with polymers and strong fluorescence. However, as the common magnetic material Fe 3 O 4 can quench their fluorescence, it is hard to synthesize Eu complex-doped magnetic fluorescent materials. To maintain fluorescence in the presence of magnetic parts, in this work, we synthesized Eu-doped magnetic microspheres with multi-layered structure. Firstly, poly-(glycidyl methacrylate) (PGMA) microspheres were prepared as templates and subsequently coated with layers of Fe 3 O 4 and SiO 2 . Then, the synthesized Eu(TTA) 3 (TPPO) 2 were added into PGMA@Fe 3 O 4 @SiO 2 microspheres in either basic or acidic conditions, and covered them with an extra sol–gel layer of silica at the same time. The microspheres exhibit a core–shell structure with sub-micron dimensions (580 nm) and possess favorable superparamagnetic properties ( M s = 22.02 A·m 2 /kg, M r = 1.37 A·m 2 /kg, H c = 0.242 A/m). But the fluorescence of Eu 3+ are significantly quenched by Fe 3 O 4 , O–H oscillators, and N–H oscillators. Finally, to exclude the quenching mentioned above, the first pure SiO 2 shielding layer and the second Eu(TTA) 3 (TPPO) 2 -dispersed SiO 2 layer were coated onto PGMA@Fe 3 O 4 microspheres to prevent the energy transfer due to the quenching centers and hold the fluorescence of Eu 3+ . These findings underscore the considerable potential of these microspheres exhibiting rapid magnetic separation and stable fluorescence for bioimaging and biosensing applications.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
·
2015
·
IF 3.444
Yi Jin,Shizhu Chen,Jianlei Duan,Guang Jia,Jinchao Zhang
With the wide applications of europium-doped Gd 2 O 3 nanoparticles (Gd 2 O 3 :Eu 3 + NPs) in biomedical fields, it will inevitably increase the chance of human exposure. It was reported that Gd 2 O 3 :Eu 3 + NPs could accumulate in bone. However, there have been few reports about the potential effect of Gd 2 O 3 :Eu 3 + NPs on bone marrow stromal cells (BMSCs). In this study, the Gd 2 O 3 :Eu 3 + nanotubes were prepared and characterized by powder X-ray diffraction (XRD), photoluminescence (PL) excitation and emission spectra, scanning electron microscope (SEM), and transmission electron microscopy (TEM). The cytotoxicity of Gd 2 O 3 :Eu 3 + nanotubes on BMSCs and the associated mechanisms were further studied. The results indicated that they could be uptaken into BMSCs by an energy-dependent and macropinocytosis-mediated endocytosis process, and primarily localized in lysosome . Gd 2 O 3 :Eu 3 + nanotubes effectively inhibited the viability of BMSCs in concentration and time-dependent manners. A significant increase in the percentage of late apoptotic/necrotic cells, lactate dehydrogenase (LDH) leakage and the number of PI-stained cells was found after BMSCs were treated by 10, 20, and 40 μg/mL of Gd 2 O 3 :Eu 3 + nanotubes for 12 h. No obvious DNA ladders were detected, but a dispersed band was observed. The above results revealed that Gd 2 O 3 :Eu 3 + nanotubes could trigger cell death by necrosis instead of apoptosis. Two mechanisms were involved in Gd 2 O 3 :Eu 3 + nanotube-induced BMSCs necrosis: lysosomal rupture and release of cathepsins B ; and the overproduction of reactive oxygen species (ROS) injury to the mitochondria and DNA. The study provides novel evidence to elucidate the toxicity mechanisms and may be beneficial to more rational applications of these nanomaterials in the future.
✓ 已验证
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Lianjun Song,Xueyu Wang,Dongqi Wang,Qian Xiao,Haowei Xu,Qiuju Li,Lanlan He,Songdong Ding
The synthesis, Eu 3+ complexation, and selective solvent extraction of Am 3+ over Eu 3+ in nitric acid solution by 2-carboxamido-6-(1 H -pyrazol-3-yl)-pyridines (A-PzPy) ligands were described. Without the aid of any lipophilic anion source, A-PzPy ligands in methyl isobutyl ketone (MIBK) diluent demonstrated a more favorable affinity of Am 3+ than Eu 3+ at high acidity levels. Slope analysis showed the formation of 1:2 metal/ligand extracted species. The extraction was a spontaneous exothermic process. The analyses of fluorescence titration, Fourier transform infrared (FT-IR), Raman, time-resolved laser fluorescence spectrum (TRLFS), electrospray ionization mass spectrometry (ESI-MS), conductivity and microcalorimetric titration revealed that the composition of complex is [Eu(NO 3 ) 2 (H 2 O)∙2(Et- p -Tol-A-PzPy)](NO 3 ). Combining the results of solvent extraction and complexation study, the extraction mechanism was proposed. Furthermore, the stability constants (log β ) and thermodynamic parameters (Δ H , Δ S , Δ G ) for complexation of Eu 3+ with Et- p -Tol-A-PzPy were also presented.
✓ 已验证
DOI
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Jiaqi Dang,Ruifeng Zhu,Wenhui Fang,Ye Hu,Ying Wu,Shixian Xin,Min Li,Bozhen Chen,Hong Zhao,Zengxi Li
It is very crucial to develop a simple and fast-responsive sensor for the detection of water content in organic solvents . Herein, three different europium-organic frameworks (Eu-MOFs): amorphous Eu-2-aminoterephthalic acid (amEu-NH 2 BDC), crystalline Eu-2-aminoterephthalic acid (cryEu-NH 2 BDC) and amorphous Eu-1,4-benzenedicarboxylic acid (amEu-BDC) are synthesized, respectively. amEu-NH 2 BDC is employed as fluorescence probe for the determination of water in ethanol. Results indicate that amEu-NH 2 BDC exhibits good performance due to its dual-wavelength fluorescence (FL) with the ligand (NH 2 BDC)-centered blue luminescence at 430 nm and Eu-centered red luminescence at 615 nm. With the increase of water contents in ethanol, the emission intensity at 430 nm increases dramatically, while that at 615 nm decreases under a single excitation at 270 nm. By measuring the ratio of emission intensity at 430 nm and 615 nm (I 430 /I 615 ), a wide concentration range from 1% to 99.5% water in ethanol is obtained with a lower detection limit value of 0.024% (S/N = 3). Besides, in the presence of water in ethanol, the fluorescence color of amEu-NH 2 BDC changes from red to blue under 365 nm UV light. Thus, the visual device for the detection of water is realized by using amEu-NH 2 BDC. Combined with the fluorescence lifetime and density functional theory, it is shown that red luminescence weakens due to dynamic quenching and non-radiative vibration energy transfer, and blue luminescence is enhanced due to the hydrogen bonding between water and carboxyl groups in the ligand, which enhances the intramolecular charge transfer process. The proposed method has characteristics of rapid response, excellent stability, high sensitivity and selectivity. Importantly, it can be successfully applied to monitor the content of water in white spirit samples.
✓ 已验证
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Xing-Hui Ren,Zi-Bo Ma,Hao-Rui Zhang,Xi-Wen He,Wen-You Li,Yu-Kui Zhang
Given the threat to human health posed by the abuse of tetracycline (TC), the development of a portable, on-site methods for highly sensitive and rapid TC detection is crucial. In this work, we initially synthesized europium-doped silicon nanoparticles (Si Eu NPs) through a facile one-pot microwave-assisted method. Due to its blue-red dual fluorescence emission (465 nm/621 nm), which was respectively attributed to the silicon nanoparticles and Eu 3+ , Si Eu NPs were designed as a ratiometric fluorescent sensor for TC detection. For the dual-signal reverse response mechanism: TC quenched the blue emission from silicon nanoparticles through inner filter effect (IFE), and enhanced the red emission through “antenna effect” (AE) between TC and Eu 3+ , the nanoprobe was able to detect TC within a range of 0.2–10 μM with a limit of detection (LOD) of 10.7 nM. Notably, the equilibrium detection time was only 1 min, achieving rapid TC detection. Furthermore, TC was also measured in real samples (tap water, milk and honey) with recoveries ranging from 95.7 % to 117.0 %. More importantly, a portable smartphone-assisted on-site detection platform was developed, enabling real-time qualitative identification and semi-quantitative analysis of TC based on fluorescence color changes. This work not only provided a novel doped silicon nanoparticles strategy, but also constructed a ratiometric sensing platform with dual-signal reverse response for intuitive and real-time TC detection.
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2019
·
IF 2.961
Jinhui Zhang,Tongtong Xuan,Peng Li,Huanrong Li,Chengxin Wang,Jing Wang
Eu 3+ complexes are the prime candidates for luminescent down-shifting (LDS) converters of solar cells due to their high luminescent quantum efficiencies (LQE), large Stoke shifts and tunable excitation. However, their instability towards heat will shorten their life in solar cells, especially for outdoor use. Besides, the optical loss of the front glass and encapsulants will trade off the enhanced efficiency by photo-conversion. In this paper, highly emissive hybrid material Eu(PPO) n -C 4 Si@NZ (HY) was obtained by assembling europium complex into three different sizes of stable zeolite L functionalized with a water-soluble stopper. Then a bi-functional layer by incorporating HY (LDS) with anti-reflective SiO 2 was developed. Benefitting from the dual functions, the as-prepared cell with HY@SiO 2 film substrate manifests an increased external quantum efficiency (EQE) in both UV and the longer wavelength regions, compared with pure glass based c-Si solar cell. In the best case, the conversion efficiency of the c-Si solar cell is increased by a relative 3.30% (from 16.386% to 16.926%).
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2026
·
IF 4.9
Shan Huang,Xincong Tu,Chunyan Pan,Shiqin Zhang,Yi Fang,Fuxiang Wei,Qi Xiao
First demonstration of europium-doped carbon dots as allosteric inhibitors of catalase. • Molecular-level elucidation of thermodynamic and structural interaction mechanisms. • Cellular validation shows concentration-dependent suppression of catalase activity. • Provides a new paradigm for designing targeted enzyme-modulating nanomaterials. • Offers fundamental insights for redox-related therapeutic applications. This study addresses a critical gap in understanding the molecular interactions between rare-earth-doped nanomaterials and antioxidant enzymes, with particular emphasis on their structural and functional implications. Red-emitting europium-doped carbon dots (Eu-CDs) were synthesized via a one-pot hydrothermal method and characterized by strong fluorescence emission at 600 nm, providing excellent optical properties suitable for bioimaging applications. Using a comprehensive multidisciplinary approach that integrates fluorescence spectroscopy, circular dichroism, molecular docking simulations, enzyme kinetics, and cellular assays, we systematically investigated the interaction mechanism between Eu-CDs and bovine liver catalase (BLC). Our results demonstrate that Eu-CDs bind specifically to an allosteric site on BLC with moderate affinity (binding constant ∼10 4 L∙mol -1 ), primarily mediated through hydrogen bonding and van der Waals interactions. Thermodynamic analysis revealed the interaction to be spontaneous and enthalpy-driven, with Δ H = −31.96 kJ∙mol -1 and Δ G = −23.30 kJ∙mol -1 . This binding induces significant conformational alterations in BLC, including a 26.9% reduction in α -helical content and a 22.4% increase in random coil structures, accompanied by a 48.7% decrease in thermal stability. Functionally, Eu-CDs were identified as non-competitive inhibitors, reducing the maximum catalytic rate by 76.2% while maintaining substrate affinity. Cellular experiments further confirmed concentration-dependent suppression of intracellular catalase activity in HepG2 cells, with 44.6% inhibition observed at 100 μg∙mL -1 Eu-CDs. These mechanistic insights not only advance fundamental understanding of nanomaterial-enzyme interactions but also establish Eu-CDs as promising candidates for modulating redox-related pathways, with potential applications in biomedical research and therapeutic development. Download: Download high-res image (329KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
Materials
·
2018
·Vol. 11
·期 5
·677
·
IF 2.467
Xiaolong Zheng,Meiyu Wang,Qiuping Li
Due to the wide potential application in the fields of sensing, lighting materials, and optical–electrical multifunctional devices, rare earth complex hybrid materials have been studied extensively over the past decades. A poly(ionic liquid)/mesoporous-based hybrid system which has been functionalized by the covalently linked europium complexes was reported here. Through surface modification with a coupling agent bearing an vinyl group, MCM-41 was chosen as the carrier matrix for poly(ionic liquids) (PILs) and europium compounds, and based on that, novel luminescent hybrid materials were prepared by confining the ionic liquid and europium complexes into the inorganic Si–O frameworks. The resulting organic/inorganic materials are chemically bonded hybrids which show good photoluminescent properties such as broad excitation spectra, line-like emission spectra, and long luminescence lifetimes. The PILs/MCM-41/Eu3+hybrid reported here is a rare earth multifunctional material which is believed to have potential applications in the field of optical–electrical materials.
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 34
·16461-16470
·
IF 3.925
Faming Xia,Xuejiao Gao,Xiaomei Shen,Hualan Xu,Shengliang Zhong
Gold nanorods (GNRs) with a strong localized surface plasmon resonance (LSPR) effect in the second near-infrared (NIR-II) window are considered as a broad platform for biomedical applications due to their excellent photothermal conversion efficiency, good biocompatibility and tunable surface functionalization. However, bare gold nanoparticles are not stable enough to obtain sufficient energy to kill tumor cells during irradiation. To improve this situation, this study used a europium-based hyaluronic acid coordination polymer (EuCP) to replace the CTAB on the surface of GNRs to prepare a nanocomposite (GNRs@EuCP) with both good biocompatibility and high photothermal conversion efficiency. Under short time radiation with a near-infrared 980 nm laser, the GNRs@EuCP nanorods exhibited good photothermal conversion capability, which is two times higher than that of bare GNRs, with a photothermal conversion efficiency of 74.6%, and exhibited excellent photostability. In addition, this study demonstrates that GNRs@EuCP has the potential for down-convert fluorescence, photoacoustic, CT and photothermal four-mode imaging. This work demonstrates that this gold-based nanocomposite will have great potential for multimodal imaging-guided photothermal therapy.
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2021
·
IF 5.165
Jiaqiang Liu,Xiandi Yu,Yan Xu,Yifang Zhao,Dan Li
Structural delamination of bulk layered metal–organic frameworks (MOFs) remains a great challenge, largely owing to a lack of general synthetic strategies. Here, we reported a simple solvent-free intercalation strategy for the delamination of rare-earth-based MOF (RE-MOF) with a topology structure of MIL-78 by tuning the chain length of quaternary ammonium salts. Four types of quaternary ammonium salts, involving tetraethylammonium bromide (TEAB), tetrapropylammonium bromide (TPAB), tetrabutylammonium bromide (TBAB), and hexadecyl trimethyl ammonium bromide (CTAB) were introduced to investigate their intercalation capabilities. It is evident in our case that the interruption/intercalation behavior of quaternary ammonium salts differs with their steric structures, and the chain-like CTAB can induce obvious delamination of MIL-78 crystals. Particularly, the CTAB-intercalated ultrathin Eu-based MIL-78 nanosheets exhibited unique selective photoelectrochemical sensing property toward trace amounts of Fe3+ ions in aqueous solution with a detection limit of 0.0899 μM at a signal-to-noise ratio of 3. These results demonstrated a green bottom-up strategy to obtain high-quality RE-MOF nanosheets for potential photocurrent response applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）