APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Di Zhang,Juanyuan Hao,Peng Wan,Dan Zhang,Quan Sun,Zongjun Liu,Fei Li,Haitao Fang,You Wang
The rapid recombination and poor redox capability of photoinduced charge carriers seriously impede the photocatalytic activity . Herein, a direct Z-scheme photocatalyst was fabricated by selectively depositing Ag 6 Si 2 O 7 nanoparticles (NPs) on the {0 4 0} facets of BiVO 4 . Owing to the facet-dependent band structure of BiVO 4 , the photoinduced electrons and holes can be pre-separated upon photoillumination and transfer to {0 4 0} and {1 1 0} facets of BiVO 4 , respectively. A rapid combination of the separated electrons at the {0 4 0} facets of BiVO 4 with holes of the Ag 6 Si 2 O 7 NPs then takes place triggering a direct Z-scheme photocatalysis. Such a charge pre-separation triggered by the faceted BiVO 4 , together with Z-scheme at the interface warrants not only effective photoinduced charge separation but also excellent redox capability owing to the increased redox potential. The photocatalytic rate constant of the optimum BiVO 4 {0 4 0}/Ag 6 Si 2 O 7 heterostructure is 28.2 and 17.2 times higher than those of pristine BiVO 4 and Ag 6 Si 2 O 7 , respectively. This study offers a new insight for constructing direct Z-scheme photocatalysts with high degradation efficiency based on facet-controlled crystals.
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高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 10
·期 2
·779-788
·
IF 12.732
Kang Yin,Xiao Xu,Muyu Wang,Jiazheng Zhou,Biwen Duan,Jiangjian Shi,Dongmei Li,Huijue Wu,Yanhong Luo,Qingbo Meng
Crystallization growth plays a crucial role in influencing the film quality and final photoelectric conversion performance of a kesterite Cu2ZnSn(S,Se)4 (CZTSSe) solar cell. Herein, an exploration of a two-step selenization strategy to control the growth kinetics of an aqueous solution derived CZTSSe film for high solar cell efficiency is reported. By synergistically exploiting the benefits of high and low temperature selenization in facilitating the CZTSSe phase formation, introducing beneficial point defect states, configuring the interfacial energy band structure, and sustaining excellent surface microstructure, a total-area cell efficiency of 12.5% has been achieved. These results demonstrate the significance of controlling the crystallization growth of CZTSSe to improve the device performance. The high cell performance achieved here is comparable to that of hydrazine or dimethyl sulfoxide solution-based cells and thus would help facilitate the development of CZTSSe solar cells toward more diversified film fabrication technologies.
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Food Science & Nutrition
·
2024
·
IF 3.5
Jialing Lin,Chuanhui Zeng,Xueli Li,Qin Tang,Jing Liao,Yan Jiang,Xianchun Zeng
Heterocyclic amines (HAs) are a group of mutagenic and carcinogenic compounds produced from the processing of high-protein foods, which include 2-amino-3-methylimidazo[4, 5-f]quinoline (IQ) showing the strongest carcinogenic effect. Camels are able to digest HAs in foods, which provide rich microbial resources for the study. Thus, camel rumen and intestinal microbiota were used to degrade IQ, and the dominant microorganisms and their degradation characteristics were investigated. After three generations of culture with IQ as the sole carbon source, the highest abundance in rumen and intestinal microbes was found in the Proteobacteria phylum. The strains of third generation of the rumen contents were mainly attributed to the genera Brevundimonas and Pseudomonas , and the dominant genera in intestine were Ochrobactrum , Bacillus , and Pseudomonas . Microorganisms were further isolated and purified from the third generation cultures. These 27 strains from the rumen (L1–L27) and 23 strains from the intestine (C1–C23) were obtained. Among them, four strains with the most effective degrading abilities were as follows: L6 (28.55% of IQ degrading rate) and C1 (25.19%) belonged to the genus Ochrobactrum , L15 (23.41%) belonged to the genus Pseudomonas , and C16 (20.89%) were of the genus Bacillus . This study suggested the application of abundant microbial resources from camels' digestive tract to biodegrade foodborne toxins.
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Journal of Extracellular Vesicles
·
2025
·Vol. 14
·期 4
·e70068
·
IF 14.5
Jiangbin Chen,Qi Tan,Zimo Yang,Wenjuan Chen,E. Zhou,Minglei Li,Jingjing Deng,Yali Wu,Jiatong Liu,Juanjuan Xu,Mengfei Guo,Yang Jin
Dendritic cell (DC)-derived extracellular vesicles (DEVs) are promising candidates for cancer vaccines, but their therapeutic effects still need further optimization. In this study, we utilized neoantigens, lipopolysaccharide and IFN-γ to induce the maturation of DCs, and then isolated DEVs derived from these mature DCs. We showed that the immune checkpoint inhibitor (anti-CTLA-4 antibody, aCTLA-4) can improve the immunostimulatory function of DEVs by directly activating T cells through immune checkpoint signal blockade. The cytokine interleukin-12 (IL-12), as one of the third signals for T cell activation, can also enhance the capability of DEVs to activate T cells directly. Based on these findings, we designed the engineered DEVs conjugated with IL-12 and aCTLA-4 (DEV@IL-12-aCTLA-4) to improve the therapeutic potential of DEVs by providing sufficient immune regulatory signals. Moreover, the carrier property of DEVs also contributes to the delivery of IL-12 and aCTLA-4 to lymph nodes. This indicates that the conjugation of DEVs with IL-12 and aCTLA-4 constitutes a complementary approach, where IL-12 and aCTLA-4 help to enhance the T cell activation effect of DEVs, and DEVs facilitate the delivery of IL-12 and aCTLA-4. Our results showed that DEV@IL-12-aCTLA-4 can enhance the Th1 immune response and reverse exhausted CD8 + T cells in the tumour microenvironment, effectively inducing robust T cell immune responses and inhibiting tumour growth in tumour-bearing mice. Overall, this study expands the theoretical foundation of DEVs and provides a universal strategy for optimizing cancer combination immunotherapy by reprogramming DEVs.
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产品关联
DOI
PubMed
高影响因子
npj Science of Food
·
2025
·Vol. 9
·期 1
·1-10
·
IF 7.8
Sun Zhi,Wang Fangfang,Zhou Peipei,Chen Di,Zuo Lihua
5-Hydroxymethylfurfural (HMF), a product of the Maillard reaction and caramelization in honey, serves as a crucial marker of food quality and thermal processing, underscoring the importance of regulatory surveillance for consumer safety. This study introduces a method for rapid, high throughput and eco-friendly detection of HMF, using derivatization in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). 5,10,15,20-Tetrakis-(4-aminophenyl)-porphyrin was employed for in-situ derivatization of aldehydes after extraction by ethyl acetate, enhancing detection sensitivity by shifting low-molecular-weight aldehydes to higher regions. The calibration curves for HMF determination exhibited outstanding linearity. The detection limit reached 0.347 mg/kg with good accuracy and precision. Variations in the content of HMF in honey during heating were also assessed, revealing the increased formation of HMF under high temperature and prolonged heating. The method’s proficiency was evidenced through the detection of various aldehydes. This method represents an advance in rapid analysis for food safety, aligning with green chemistry principles.
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Dongxing Dong,Zhiqiang Cheng,Jingjing Zhang,Zhengyi Gu,Zhaolian Han,Wenli Hou,Xiaoli Lv
Pressure ulcer dressings with different functions can enhance wound healing ability to varying degrees; however, pressure ulcer dressings that integrate various functions and break the resistance of bacteria to traditional antibiotics have not been widely studied. We proposed a self-pumping/super-absorbent/transportable drug dressing (PLD-SLD), polycaprolactone (PCL)/sodium alginate (SA) was used to load platelet-derived growth factor (PDGF) and lidocaine hydrochloride (LID) by Janus electrospinning and self-assembly technology, and Ɛ-polylysine was used as a biological bacteriostatic agent to prepare a multi-layer dressing. SEM showed that the dressing had a fluffy structure. The dressing can pump the exudate to the SA layer away from the skin. The swelling ratio reached 1378.667 ± 44.752 %. Coagulate blood in 5 min. On the 8th day, the unclosed area rate of the PLD-SLD dressing group was 16.112 ± 0.088 % lower than that of the model group. Importantly, the dressing can induce the expression of CD31, VEGF, α-SMA, and reduce the expression of CD68, thereby giving priority to wound healing. There was no scar formation after healing. In this study, a new dressing preparation method was proposed for the problems of exudate management, infection control, pain relief and healing promotion of stage 3–4 pressure ulcer healing.
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PubMed
高影响因子
Journal of Materials Chemistry A
·
2022
·Vol. 10
·期 42
·22791-22802
·
IF 14.511
Xing-Ye Chen,Muhammad Ishaq,Nafees Ahmad,Rong Tang,Zhuang-Hao Zheng,Ju-Guang Hu,Zheng-Hua Su,Ping Fan,Guang-Xing Liang,Shuo Chen
The existence of various detrimental defects inside the absorber layer is a major obstacle limiting the performance of kesterite Cu2ZnSn(S,Se)4 (CZTSSe) thin-film solar cells. Cationic substitution is a viable strategy for overcoming this challenge and has drawn tremendous research attention. In this work, a dual-cation substituted CZTSSe involving Ag and Ti to separately occupy partial Cu and Sn lattice sites is proposed. Under 6% Ag and 1% Ti dual-cation substitution, the champion CZTSSe device delivers a highly interesting efficiency of 12.73%, accompanied by an outstanding VOC of 530 mV. Further investigation demonstrates that Ag introduction can improve the density and crystallinity of CZTSSe thin films while decreasing the concentration of CuZn acceptor defects. Further Ti substitution can effectively eliminate fine grains and reduce the defect density of CuSn and [2CuZn + SnZn] defects, as well as the core level defects. This work explores the synergistic effect of Ag, Ti dual-cation substitution in CZTSSe solar cells for the first time, and the clarified device performance improvement mechanism opens up promising possibilities for the bright development of CZTSSe thin-film photovoltaic technology.
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高影响因子
Small
·
2020
·Vol. 16
·期 39
·2002718
·
IF 11.459
Daping Qiu,Min Li,Cuihua Kang,Jinying Wei,Feng Wang,Ru Yang
The intrinsic properties of carbon-based material and the voltage window of electrolyte are the two key barriers to restrict the energy density of carbon-based supercapacitors (SCs). Herein, a cucurbit[6]uril-derived nitrogen-doped hierarchical porous carbon (CBC x ) with unique pore structure characteristics is synthesized and successfully applied to construct SCs based on different electrolyte systems. Owing to narrow pore size distribution (0.5–4 nm), colossal ion-accessible pore volume, prominent supermesopore volume, and reasonable heteroatom configuration, the CBC x -based SCs demonstrate excellent electrochemical performances with high operating voltages in two distinct systems. The optimal SCs can output a maximum energy/power density of 18 Wh kg −1 (11.1 Wh L −1 )/20 kW kg −1 (12.3 kW L −1 ) with an operating voltage of 1.2 V in potassium hydroxide aqueous electrolyte, as well as an ultralong cycle life of up to 50 000 cycles (0.046% decay per 100 cycles). Furthermore, the optimal SCs deliver an exceptionally high energy/power density of 95 Wh kg −1 (58.4 Wh L −1 )/70 kW kg −1 (43 kW L −1 ) with an ultrahigh operating voltage of 3.5 V in 1-ethyl-3-methylimidazolium tetrafluoroborate electrolyte. This work opens up a new application field for cucurbit[6]uril and provides an alternative avenue for optimizing the performances of carbon-based materials for SCs.
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高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2021
·
IF 5.875
Hongji Liu,Jinju Nie,H.C. Stephen Chan,Hailu Zhang,Liang Li,Hongqing Lin,Henry H.Y. Tong,Ande Ma,Zhengzheng Zhou
Herein, we reported a new bergenin : 4-aminobenzamide ( BGN-4AM ) cocrystal with significantly enhanced solubility and low hygroscopicity probed from two aspects such as phase solubility diagrams and theoretical calculations. Compared with anhydrous BGN , BGN-4AM solubilities in water and different buffer solutions (pH = 1.2, 4.5, 6.8) increase significantly. It is noted that BGN-4AM solubility in pH = 6.8 buffer solution presents 32.7 times higher than anhydrous BGN . Interestingly, BGN-4AM (0.31 ± 0.07%) showcases lower hygroscopicity than anhydrous BGN (9.31 ± 0.16%). The predicted and experimental solubilities agree with each other when considering solubility product ( K sp ) and solution binding constant ( K 11 ) in phase solubility diagrams, indicating the solution complexes formation occurs. Further crystal surface-water interactions and Bravais, Friedel, Donnay-Harker (BFDH) analyses based on Density Functional Theory with dispersion correction (DFT- d ) methods support the enhanced solubility. The water probe demonstrates an average interaction energy of −6.48 kcal/mol on the 002 plane of BGN-4AM , and only −5.47 kcal/mol on the 011 plane of BGN monohydrate. The lower lattice energy of BGN-4AM guarantees its lower hygroscopicity than BGN monohydrate. BGN-4AM with enhanced solubility and low hygroscopicity can be a potential candidate for further formulation development.
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高影响因子
Journal of Environmental Chemical Engineering
·
2020
·
IF 4.3
Wenjun Liu,Zhaohui Li
Metallic Au nanoparticles (NPs) are active catalysts in many chemical reactions. However, small-size Au NPs are difficult to obtain since they tend to agglomerate due to their high surface energies. Herein, we reported a facile and green hydrothermal process, using graphene oxide (GO) as the RGO precursor, HAuCl 4 as Au precursor and L-cysteine (L-cys) as both cross-linker and reducing agent, to fabricate an Au/RGO composite aerogel. During the hydrothermal process, the reduction of GO/HAuCl 4 , the oxidation of L-cys to produce disulfide linkage, and the self-assembly of RGO aerogel occurs simultaneously, leading to the resultant RGO aerogels uniformly and intimately embedded with disulfide protected ultrasmall Au NPs with an average size of 1.3 nm. The as-obtained Au/RGO composite aerogel exhibited superior catalytic performance for reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP), with a total transformation of 4-NP achieved in 4 min. The much higher activity over Au/RGO aerogel as compared with unsupported thiol-capped Au NPs can be attributed to the synergistic effect of metallic Au and RGO. Moreover, Au/RGO composite aerogel also showed high stability and can be easily separated from the reaction systems for recycling. No obvious decrease of catalytic reduction activity was observed over the Au/RGO aerogel after five cycles. Considering the high price of metallic Au, the embedding of Au NPs in three-dimensional RGO aerogels to facilitate its recycling is extremely appealing for its practical applications.
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高影响因子
Canadian Journal of Chemistry
·
2021
·Vol. 99
·期 10
·
IF 1.118
Xiaoxia Li,Shuaida Zhu,Qi Jia,Haixia Zhao,Yuqi Cao,Yuying Ma,Shuangqi Hu,Xiong Cao
In this work, it is shown that MoO3-x has a positive effect on the thermal decomposition of ammonium perchlorate based molecular perovskite (H2DABCO)[NH4(ClO4)3] (DAP-4). MoO3-x was prepared by heat treatment, and the morphology, structure, and thermal decomposition performance were characterized. The morphology and structure characterization results showed that MoO3-x was an irregular layered structure material and the Mo element was mainly in the +6 chemical valence state, with a small amount of Mo5+. Thermal analysis results showed that the thermal decomposition peak temperature of DAP-4 was effectively reduced from 394.4 °C to 353.7 °C, 321.4 °C, and 312.5 °C in the presence of 1%, 5%, and 10% MoO3-x, respectively. It is particularly worth noting that the maximum heat release rate of the DAP-4/10% MoO3-x mixture was increased by 4.9 times compared with pure DAP-4. Through the two classic thermal decomposition kinetic methods, Kissinger and Starink, the reliable kinetic parameters of DAP-4/MoO3-x were obtained. The increase of the reaction rate constant k indicated that the maximum thermal decomposition reaction rate of DAP-4 was effectively improved. This work provided a feasible technology for using MoO3-x as an effective catalyst to improve the thermal performance of DAP-4.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2016
·Vol. 51
·期 22
·10229-10244
·
IF 2.302
Ban Jianfeng,Zhu Linjiang,Chen Shaojun,Wang Yiping
Aiming to elucidate the influence of liquid crystal fillers on the structure and properties of liquid-crystalline (LC) shape-memory polyurethane (SMPU) composites, a series of LC-SMPU composites are successfully prepared by adding various concentrations of 4-dodecyloxybenzoic acid (DOBA) to shape-memory polyurethane containing 40 wt% hard segment content (SMPU40). The structure, morphology, thermal properties, liquid crystalline properties, and shape memory properties are systematically investigated. The results demonstrate that DOBA is successfully incorporated into the polymer matrix of SMPU40 without interrupting the dimerization structure of DOBA that allows it to exhibit LC properties. The incorporated DOBA not only improves the crystallizability of the soft segment but also promotes the crystallizability of the hard segment. The isothermal crystallization kinetics further reveal that the crystallization rate of the hard segment decreases as the DOBA content increases, and the crystallization of the LC-SMPU composites nucleates in a similar manner. The LC-SMPU composites are composed of a DOBA phase and an SMPU phase, which further forms soft phase–hard phase microphase separation structures. The composite tends to only maintain the nematic LC properties of DOBA due to the interruption of polyurethane chains. However, the LC-SMPU composites exhibit good triple-shape memory effects. The first step of strain recovery is associated with the melting transition of soft segment crystals of the polyurethane matrix, and the second step of strain recovery is resulted from the melting transition of the DOBA crystals.
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高影响因子
危险品化学品经营许可证（带存储）