ANALYTICA CHIMICA ACTA
·
2018
·
IF 5.123
Ye Hu,Yajiao Huang,Yanying Wang,Chunya Li,WingLeung Wong,Xiaoxue Ye,Dong Sun
ZnAgInS quaternary quantum dots were prepared using glutathione as the capped reagent. Gold nanoparticles (GNPs) were integrated with ZnAgInS QDs to provide a GNPs/ZnAgInS QDs nanocomposite. The morphological image, component and crystal structure of GNPs/ZnAgInS QDs were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). A glassy carbon electrode surface was coated with GNPs/ZnAgInS QDs nanocomposites to construct an interface for immobilizing the antibody of hepatitis B virus surface antigen (anti-HBsAg). By employing GNPs/ZnAgInS QDs as a photoactive element, a photoelectrochemical immunosensor for hepatitis B virus surface antigen (HBsAg) was developed. The results indicate that gold nanoparticles can dramatically enhance the photocurrent response of ZnAgInS QDs and thus improving the sensing performances of the immunosensor. The experimental conditions including incubation time , incubation temperature , and ascorbic acid concentration were optimized. The relative photocurrent decline [ R i = Δ I / I 0 = ( I 0 − I )/ I 0 ] shows a linear relationship to the logarithm of HBsAg concentration [lg( c , ng mL −1 )] in the range from 0.005 to 30 ng mL −1 . A detection limit of 0.5 pg mL −1 was obtained. The immunosensor shows excellent sensitivity, selectivity , stability and reproducibility. The HBsAg concentrations in clinical serum samples were also accurately determined with this new photoelectrochemical immunosensor.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Inorganic Chemistry Frontiers
·
2018
·Vol. 5
·期 8
·1787-1794
·
IF 5.106
Yanna Chen,Min Zhang,Cong Hu,Zhihua Yang,Shilie Pan
As the first reported examples of borates in the Zn–Sc–B–O system, Ba2ZnSc(BO3)3 and Ba4Zn5Sc2(BO3)8 were synthesized through a high-temperature solution method. The structure of Ba2ZnSc(BO3)3 can be described as ZnO4 tetrahedra connecting ScO6 octahedra to form a [ZnScO9]13− dimer, which further bonds with seven BO3 triangles to form a 2∞[ZnSc(BO3)3] layer, and the Ba atoms distribute in the voids between the layers. In contrast, in Ba4Zn5Sc2(BO3)8, Zn–O chains composed of 4- and 6-coordinated Zn atoms link with Sc2O8 dimers to form a Zn–Sc–O layer, and the BO3 triangles and Ba atoms fill in the voids between the layers. Interestingly, the special [Zn2(BO3)6]14− cluster is found in Ba2ZnSc(BO3)3, which is different from the 2D layers or 3D frameworks of the Zn–B–O configurations in other zincoborates. Moreover, the lowest-coordinated ScO5 polyhedra, as well as the coexistence of two types of ZnOn units (n = 4 and 6), are observed for the first time in Ba4Zn5Sc2(BO3)8. These fascinating results can promote the design of novel borates with BO3 units and enrich the borate structure chemistry.
✓ 已验证
产品关联
DOI
高影响因子
Micro & Nano Letters
·
2018
·Vol. 13
·期 8
·1175-1178
·
IF 0.841
Qiao Cheng,Yu He,Yili Ge,Gongwu Song
In this work, 3-aminophenylboronic acid was used as the starting materials to construct boron and nitrogen co-doped carbon dots with tunable dual-emission intensity at 420 and 540 nm with different excitation at 360 and 500 nm, respectively. The dual-emission carbon dots sensor is employed for rapid and sensitive fluorescence-enhancing detection of Pb 2+ . Compared with previous reported methods, their method showed better linear ranges or detection limits. Under the optimal conditions, the limit of detection of 0.9 nM for Pb 2+ was reached with a wide range of 9 nM to 438 μM. The authors believe that the established method has more opportunities for application for other environmental targets.
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2018
·Vol. 8
·期 9
·372
·
IF 3.465
Lin Li,Bo Jiang,Zhehao Sun,Qian Zhang,Duyu Li,Dawei Tang
This paper describes the synthesis of a series of La1.4Sr0.6Ni1−xCoxO4perovskite OCs using co-precipitation method by employing Co and Ni as the B-site components of perovskite and the synergetic effect of Co doping on chemical looping reforming of ethanol. A variety of techniques including N2adsorption-desorption, X-ray diffraction (XRD), transmission electron microscopy (TEM) and H2temperature-programmed reduction (TPR) were employed to investigate the physicochemical properties of the fresh and used OCs. The activity and stability in chemical looping reforming were studied in a fixed bed reactor at 600 °C and a S/C ratio of three. The synergetic effect between Ni and Co was able to enhance the catalytic activity and improve the stability of perovskite OCs. La1.4Sr0.6Ni0.6Co0.4O4showed an average ethanol conversion of 92.4% and an average CO2/CO ratio of 5.4 in a 30-cycle stability test. Significantly, the H2yield and purity reached 11 wt.% and 73%, respectively. The Co doping was able to significantly improve the self-regeneration capability due to the increase in the number of oxygen vacancies in the perovskite lattice, thereby enhancing the sintering resistance. Moreover, Co promotion also contributes to the improved WGS activity.Keywords:chemical looping reforming;perovskite;Ni-Co synergy
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2013
·Vol. 51
·期 13
·2939-2947
·
IF 3.543
Zong-Quan Wu,Cheng-Gang Qi,Na Liu,Ying Wang,Jun Yin,Yuan-Yuan Zhu,Long-Zhen Qiu,Hong-Bo Lu
In this article, the synthesis of a series of conjugated rod–rod block copolymers based on poly(3-hexylthiophene) (P3HT) and poly(phenyl isocyanide) (PPI) building blocks in a single pot is presented. Ni-catalyzed Grignard metathesis polymerization of 2,5-dibromo-3-hexylthiophene and subsequent addition of 4-isocyanobenzoyl-2-aminoisobutyric acid decyl ester in the presence of Ni(dppp)Cl 2 as a single catalyst afford P3HT- b -PPI with tunable molecular weights and compositions. In solid state, microphase separation occurred as differential scanning calorimetric analysis of P3HT- b -PPI revealed two glass transition temperatures. In solutions, the copolymers can self-assemble into spherical aggregates with P3HT core and PPI shell in tetrahydrofuran and exhibit amorphous state in CHCl 3 . However, atomic force microscopy revealed that the block copolymers self-assemble into nanofibrils on the substrate. These unique features warrant the resultant conjugated rod–rod copolymers' potential study in organic photovoltaic and other electronic devices. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 2939–2947
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2012
·Vol. 19
·期 12
·1-8
·
IF 1.733
Ma Chi,Wang Bing,Xiong Cheng-Dong,Chen Dong-Liang,Xiong Zuo-Chun
Control of dimensional stability is crucial for using electrospun membranes in biomedical and tissue engineering applications. In this study, the contraction of electrospun membranes of poly( l -lactide-co-glycolide) (PLLGA) after stretch was investigated. Then, by adding PLLGA-b-polyethylene glycol (PLLGA-PEG), the contraction of the membranes was controlled. In addition, the mechanical properties of the membranes were investigated. On the basis of the strain–stress behavior of the membranes, an elongation of 50 % was used to investigate the orientation degrees of the membrane fibers. On the basis of the morphology of the stretched membranes, the contraction was found to depend on the orientation degree of fibers after stretch. A linear relationship between the contraction and degree of orientation after stretch was confirmed. Two-dimensional fast Fourier transform (2D FFT) analysis of the scanning electron microscopy (SEM) images of the membranes was used to quantify the orientation degree. It was surmised that the different orientation degrees were responsible for the different morphologies and thermal behaviors of the membranes.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL LETTERS
·
2013
·
IF 0.965
Xiuying Liu,Bing Bai,Qian Zhou,Yingchao Yu,Shujuan Ji
Molecularly imprinted polymers grafted on to the surface of carboxyl-modified multiwalled carbon nanotubes were developed using methacrylic acid as a functional monomer and trihydroxymethylpropyl trimethylacrylate as a crosslinker for application to rhodamine B determination. The synthesis, characteristics, and evaluation of the molecularly imprinted polymer are described. The apparent morphology of the polymers was characterized by scanning electron microscopy. To evaluate the binding ability of the molecularly imprinted polymers, equilibrium binding experiments were conducted and revealed the maximal binding capacity to be 561.54 µg g−1. The introduction of nanomaterials into the polymer composite made important contributions to the affinity enhancement and recognition properties of the molecularly imprinted polymers. Moreover, the polymers were preliminarily applied as an adsorbent for separation and extraction of Rhodamine B from dried chili powder samples, based on solid phase extraction technology. The calibration curve was linear in the range of 0–7 µg mL−1. For all tested samples, recoveries were reliable and in the range of 101.75–109.73%. The relative standard deviation ranged from 6.43–14.32%, which demonstrated that the polymer has potential for preconcentration of Rhodamine B from chili powder samples.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2017
·
IF 6.395
Kening Sun,Jia Liu,Jie Feng,Hong Yuan,Minjie He,Chunming Xu,Zhenhua Wang,Wang Sun,Jinshuo Qiao
B-site substituted Sr 2 Fe 1.4 X 0.1 Mo 0.5 O 6-δ (SFXM, X = Bi, Al and Mg) are evaluated as anode materials for hybrid direct carbon fuel cells (HDCFCs). The structure, morphology, conductivity and catalytic activity of the as-prepared SFXM anode are systematically investigated. Under a reducing atmosphere, the exsolution of metallic Fe from the SFXM perovskite lattice are demonstrated by the XRD , SEM and TEM observations. Further element valence analysis on reduced SFXM suggests the X doping significantly alters the Fe 3+ /Fe 2+ and Mo 6+ /Mo 5+ ratio, and thus beneficial to the intrinsic conductivity of SFXM. All these advantages are responsible for the good electrochemical performances of SFXM anodes. Meanwhile, among these SFXM anodes, the conductivity, catalytic activity and electrochemical performance all obey the order of SFBM > SFAM > SFMM. The maximum power densities of the La 0.8 Sr 0.2 Ga 0.8 Mg 0.2 O 3 electrolyte supported single cell with SFBM as the anode reaches 399, 287 and 141 mW cm −2 at 800 °C, 750 °C and 700 °C, respectively. Such designed B-site substitution perovskites have great potential to be applied as HDCFC anode materials.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 17
·
IF 1.86
Chunhui Du,Xumin Ma,Jing Li,Chunjin Wu
This study describes the fabrication and properties of poly(vinylidene fluoride) (PVDF) filtration membranes modified by blending with ionic liquid block copolymer P(MMA- b -MEBIm-Br), which is synthesized via reversible addition-fragmentation chain transfer polymerization method. The attenuated total reflectance-Fourier transform infrared spectroscopy and X-ray photoelectron analyses reveal that the ionic liquid block copolymers are immobilized on PVDF membrane surface. The modified PVDF membrane exhibits excellent charged and antifouling properties because of the charged and hydrophilic properties of the copolymer. Scanning electron microscopy and atomic force microscopy also indicate the morphological characteristics of the membrane and demonstrate that the surface porous structure becomes denser after adding the copolymer. The data of filtration and the zeta potential of the membranes suggest that the charged properties of the ionic liquid block copolymers are mainly responsible for the improvement of the reversible fouling ratio and the decrease in the total fouling ratio of the membranes. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44751.
✓ 已验证
产品关联
DOI
高影响因子
CELLULAR SIGNALLING
·
2024
·
IF 4.4
Wentao Hu,Menghan Wang,Guifang Sun,Limin Zhang,Hong Lu
Parkinson's disease (PD) is a gradually debilitating neurodegenerative syndrome. Here, we analyzed GSE7621 chip data obtained from the Gene Expression Omnibus (GEO) database to explore the pathogenesis of PD. Early B Cell Factor 3 (EBF3), a member of the highly evolutionarily conserved EBF-transcription factor family, is involved in neuronal development. EBF3 expression is low in the substantia nigra of patients with PD. However, whether EBF3 is implicated in dopaminergic neuron death during PD has not yet been investigated. Therefore, we aimed to reveal the potential anti-apoptotic effect and molecular mechanism of EBF3 in PD. We established a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model in vivo and a 1-methyl-4-phenylpyridine (MPP + )-induced SH-SY5Y cell model in vitro . EBF3 was downregulated in the substantia nigra of PD mice and SH-SY5Y cells treated with MPP + , and the m6A methylation modification level was low. Fat mass and obesity-associated protein (FTO) siRNA upregulated m6A methylation modification of EBF3 and extended the EBF3 mRNA half-life. Functionally, as demonstrated by the results of the open-field test, pole test and gait analysis, EBF3 overexpression ameliorated MPTP-induced behavioral disorder. Further, EBF3 overexpression suppressed neuronal apoptosis in vivo , as evidenced by decreased TUNEL + cells, and the increased activation of caspase-3 and caspase-9. Similar results were obtained in vitro , as reflected by increased cell viability, decreased LDH activity and restored mitochondrial function, collectively protecting SH-SY5Y cells from MPP + -induced apoptosis. Mechanistically, the results of luciferase reporter, ch-IP and DNA pull-down assays confirmed that, as a transcription factor, EBF3 bound to the promoter of CNTNAP4 (a protein associated with neuronal differentiation) and directly regulated CNTNAP4 transcription. Strikingly, CNTNAP4 knockdown markedly abolished the effect of EBF3 on cell apoptosis, thus aggravating PD. In conclusion, the low level of m6A methylation modification may contribute to the low expression of EBF3 during PD. Additionally, EBF3 attenuates PD by activating CNTNAP4 transcription, suggesting that EBF3 may be a novel therapeutic target in PD.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WATER AIR AND SOIL POLLUTION
·
2025
·Vol. 236
·期 2
·1-12
·
IF 3
Zhu Xiao,Yu Cao,Zhu Mingxin,Zhou Hua,Pan Shunlong
The advanced peracetic acid (PAA) oxidation technology has a wide application prospect in the field of wastewater treatment for its high efficiency, environmental protection and wide application. In this work, cobalt tetraferrote (CoFe 2 O 4 ) was used to activate PAA to degrade acid red B. The effects of CoFe 2 O 4 catalyst dosage, PAA concentration, initial pH value and anion on the decolorization efficiency of acid red B were investigated by intermittent single factor experiments. The optimal reaction conditions for the degradation of 0.1 mM acid red B in the CoFe 2 O 4 /PAA system were as follows: catalyst dosage of 0.008 g, PAA concentration of 1 mM, and initial pH = 7. After 30 min of reaction, the degradation rate of acid red B reached was as high as 99.5%. The coexistence of CoFe 2 O 4 /PAA with low concentrations of anions and humic acid (HA) had negligible effects on the catalysis of acid red B, while the coexistence with higher concentrations of HCO 3 − , H 2 PO 4 − and HA inhibited the degradation behaviors. Quenching experiments confirmed that there were a large amount of R-O• and a small amount of •OH in the CoFe 2 O 4 /PAA system, and 1 O 2 played an important role in the degradation process. After 6 cycles, the catalytic performance of CoFe 2 O 4 remained above 98.6%, showing stable catalytic performance, which were also confirmed by FTIR and XPS. This work provided a new way for effectively treating azo dye containing waste water.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jiangli Song,Hanlian Chen,Rongkai Pan,Fangyu Jin,Jie Tang,Qianqian Huang,Guohua Zhou,Xiumei Song
Understanding the interactions between small molecules and calf thymus deoxyribonucleic acid (ctDNA) is critical for certain aspects of drug discovery. In this study, three 11 H -indeno[1,2-b]quinoxalin-11-one thiosemicarbazones were synthesized and their interaction with ctDNA was examined through various spectroscopic techniques, including ultraviolet (UV) spectroscopy, fluorescence spectroscopy, and circular dichroism (CD) spectrum, and through physicochemical methods, including viscosity measurements. In addition, the effects of these thiosemicarbazone compounds 4a, 4b and 4c on several cancer cell lines were explored. The results of UV absorption, fluorescence quenching and CD experiments indicated that compounds 4a, 4b and 4c primarily bound to ctDNA by an intercalation. This mode of interaction was further corroborated by viscosity measurements. Docked poses of compound 4a revealed that it formed a crucial N position hydrogen bond with the DNA receptor. The chemical structure of compound 4a was further confirmed by X-ray crystallographic analysis. Through biological evaluation, it was found that the in vitro cytotoxicity of three compounds agreed with the order of their binding strength to ctDNA, indicating that the antitumor activity of these compounds correlated with their binding affinity to ctDNA.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）