COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Tingting Li,Yukun An,Jiashuang Li,Zhiming Zhang,Lin Liu,Libao An
A bimetallic Ln-MOF nanofibrous membrane (NFM) was successfully fabricated by in situ growth of Eu/Tb-MOF crystals onto electrospun polycaprolactam (PA6) nanofibers . For better combining with PA6 nanofibers , the Eu/Tb-MOFs were made into nanocrystals . Characterization with PXRD , FT-IR, EDS and XPS confirmed that the crystal structure of the Eu/Tb-MOFs maintained well on PA6 NFM. The as-prepared Eu/Tb-MOF@PA6 NFM can be used as a colorimetric fluorescent test strip for instant detection of the volume ratio of 1, 4-dioxane in 1, 4-dioxane-glycol mixture. With the increase of 1, 4-dioxane, the test strip presented color changes from green to red, which can be easily distinguished by the naked eye. In view of this, the conversion rate of the condensation reaction of glycol to 1, 4-dioxane will be preliminarily estimated without the help of equipment. More importantly, the test strip exhibited better convenience and reversibility compared with powdered Ln-MOFs because no separation process was needed for test strip before and after recovering. Benefiting from sufficient amide groups in PA6 for anchoring Eu/Tb-MOF particles, the test strip showed satisfactory stability in cycling experiments. This work will provide a new insight into the development of fluorescent test strip based on electrospun MOF NFM for quantitatively monitoring the reaction process.
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高影响因子
RSC Advances
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2012
·Vol. 2
·期 32
·12245-12250
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IF 0
Hua-Neng Xu
Aqueous binary surfactant solutions, based on the cloud point phenomenon, have been utilized to design efficient extraction of a variety of substances. In this study, the effect of the anionic surfactant sodium dodecyl sulfate (SDS) on the clouding behaviour of aqueous nonionic surfactant solutions of Triton X-114 (TX-114), in the presence of 100 mM sodium chloride (NaCl), has been studied as a function of temperature by means of turbidity, dynamic light scattering (DLS), and rheo-small angle light scattering (Rheo-SALS). It is found that the addition of 2 mM SDS lowers the phase separation temperature of the surfactant solution by about 2 °C. The hydrodynamic radius of the surfactant aggregates increases with increase of temperature and SDS concentration. The change in microstructure of the surfactant aggregates at different temperature and SDS concentrations is also reflected by the characteristic length and aspect ratio extracted from their SALS patterns, which range from 269 to 623 nm and from 1.01 to 1.40, respectively. The increasing characteristic length and aspect ratio with SDS concentration indicate the growth of the mixed surfactant aggregates is in the flow direction and these elongated aggregates can align under shear.
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DOI
PeerJ
·
2024
·
IF 2.3
Zhaohong Wang,Hui Chen,Xufan Cai,Heqi Bu,Shengzhang Lin
Background Andrographolide (Andro), an extract of Andrographis paniculate (Burm.f.) Wall. ex Nees (Acanthaceae), possesses diverse biologically active properties. However, the precise mechanisms and effects of Andro on pancreatic cancer (PC) remain unclear. Methods The cytotoxic potential of Andro and underlying mechanism towards PC cells was investigated through in vitro experiments and a xenograft mouse model. PC cells were first subjected to varying concentrations of Andro. The reactive oxygen species (ROS) was assessed using flow cytometry and DCFH-DA staining. The apoptosis rate was detected by flow cytometry. Additionally, western blot was applied to evaluate the expression levels of cleaved-caspase-3, DJ-1, LC3-I, LC3-II, and p62. To further elucidate the involvement of ROS accumulation and autophagy, we employed N-acetylcysteine as a scavenger of ROS and 3-Methyladenine as an inhibitor of autophagy. Results Andro demonstrated potent anti-proliferative effects on PC cells and induced apoptosis, both in vitro and in vivo . The cytotoxicity of Andro on PC cells was counteracted by DJ-1 overexpression. The reduction in DJ-1 expression caused by Andro led to ROS accumulation, subsequently inhibiting the growth of PC cells. Furthermore, Andro stimulated cytoprotective autophagy, thus weakening the antitumor effect. Pharmacological blockade of autophagy further enhanced the antitumor efficacy of Andro. Conclusion Our study indicated that ROS accumulation induced by the DJ-1 reduction played a key role in Andro-mediated PC cell inhibition. Furthermore, the protective autophagy induced by the Andro in PC cells is a mechanism that needs to be addressed in future studies.
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PubMed
高影响因子
ELECTROCHEMISTRY COMMUNICATIONS
·
2012
·
IF 4.859
Bin Li,Mengqing Xu,Tiantian Li,Weishan Li,Shejun Hu
In this paper, we reported a novel solid electrolyte interphase (SEI) formation additive, prop-1-ene-1,3-sultone (PES), used in propylene carbonate (PC)-based electrolyte for lithium ion batteries . The effect of PES on the co-intercalation of PC into anode and the battery performance was investigated by energy calculation, cyclic voltammetry and battery charge–discharge test. The theoretical calculations and the voltammograms show that PES can be reduced prior to propane sultone (PS), a practical SEI formation additive for lithium ion batteries. Charge–discharge test shows that the use of PES can suppress successfully the co-intercalation of PC with lithium ions into graphite and the LiCoO 2 /graphite battery using PES exhibits better performance than that using PS as the SEI formation additive.
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高影响因子
JOURNAL OF PLANT PATHOLOGY
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2024
·
IF 2.2
Reymick Okwong Oketch,Duan Bin,Feng Zhao,Zhang Yong Hua,Ouyang Qiuli,Kaaya Archileo N.,Tao Nengguo
Management of Penicillium digitatum requires use of highly effective fungicides that are not prone to drug resistance and are safe to humans and the environment. This study examined the fungicidal potential of combinations of cuminaldehyde (CA) + trans-2-hexen-1-al (TH) and CA + Citral. Both CA + TH and CA + Citral exhibited enhanced fungitoxicity against P. digitatum than CA, citral or TH alone. The minimum inhibitory concentration (MIC) of CA + Citral consisted of 0.13 ml/L CA and 0.3 ml/L citral, representing a synergistic interaction. MIC of CA + TH consisted of 0.12 ml/L CA and 0.15 ml/L TH, representing an additive interaction. The minimum fungicidal concentration (MFC) of CA + Citral and of CA + TH consisted of 0.26 ml/L CA and 0.6 ml/L citral, and 0.18 ml/L CA and 0.24 ml/L TH, respectively. 10×MFC CA + Citral in Tween-80 (WCI) delayed onset of hyphal growth in fruits inoculated with P. digitatum to day 5 compared to day 4 in the 10×MFC CA + TH in Tween-80 (WCT) treatment, and day 3 for the control samples. Daily green mold disease incidence and disease severity were much lower in WCI and WCT treatments than in the 10×MFC CA in Tween-80 (WCA) treatment and in control samples. Our results show that WCI was much fungitoxic against P. digitatum than WCT and WCA, its effect being comparable to that of imazalil. Additionally, at 25 ± 2 °C and 85–90% relative humidity, both WCI and WCT markedly preserved fruit quality by day 6 of treatment. WCI and WCT are thus, safe, cheap and highly effective alternatives to chemical fungicides being used to control postharvest green mold in citrus fruits.
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高影响因子
BIOORGANIC CHEMISTRY
·
2024
·
IF 4.5
Yi Chen,Shasha Song,Yongfang Wang,Lili Wu,Jianbing Wu,Zhengmeng Jiang,Xinyu Li
Psoriasis (PSO) is a common inflammatory skin disease caused by multiple factors. Magnolia officinalis is an important medicinal plant in China, with various values such as ecology, medicine, food, and daily chemicals. However, its diverse application potential has not been fully explored. Magnolol (MGO) is the main active compound of Magnolia officinalis with significant anti-inflammatory effect. To investigate the application potential of MGO in inflammatory skin disease, the effects and underlying mechanisms of topical MGO treating psoriasis were explored in this study. Network pharmacology and molecular docking firstly predicted that topical MGO may treat psoriasis by regulating pyroptosis pathway and acting on caspase-1 (CASP1). In vitro experiments then demonstrated that MGO could inhibit the level of inflammatory cytokines and the key protein expression of NOD-like receptor protein 3 (NLRP3)/Caspase-1 pathway in lipopolysaccharide (LPS)-stimulated phorbol 12-myristate 13-acetate (PMA)-differentiated THP-1 cells. Meanwhile, MGO could inhibit CuSO 4 -induced neutrophils migration in Tg (mpx:EGFP) zebrafish by suppressing inflammation and pyroptosis. This study further indicated that topical application of MGO ameliorated imiquimod (IMQ)-induced psoriasis-like dermatitis by reducing the release of inflammatory factors and decreasing the key protein expression of pyroptosis-related NLRP3/Caspase-1 pathway. Metabolomics analysis revealed that topical application of MGO could significantly regulate tryptophan metabolism and affect the level of tryptophan in skin lesions. Tryptophan could also regulate inflammation-related genes and inhibit pyroptosis-related NLRP3/Caspase-1 pathway in LPS-stimulated PMA-differentiated THP-1 cells. In conclusion, this study suggested that topical MGO may ameliorate psoriasis-like dermatitis by inhibiting NLRP3/Caspase-1 pathway and regulating tryptophan metabolism.
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PubMed
高影响因子
Analytical Methods
·
2024
·Vol. 16
·期 35
·5959-5970
·
IF 2.7
Zhang Jingru,Chu Hongtao,Chen Jiaqi,Wang Qian,Qin Shili,Gao Lidi,Ma Wenhui,Li Jun,Zhao Ming,Zhang Weibing
In this study, three different materials were prepared: dendritic fiber-type silica (KCC-1), zeolitic imidazolate framework-8 (ZIF-8), and a new composite material called KCC-1@ZIF-8. These materials were synthesized using microemulsion, stirring, and coating methods, respectively. The properties of the materials were characterized using various techniques such as transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), TGA and X-ray diffraction (XRD). The results showed that KCC-1@ZIF-8 exhibited a significant increase in the BET surface area and pore size compared to the individual components KCC-1 and ZIF-8. These improved properties of the composite material were beneficial for enhancing the adsorption capacity. The effects of initial concentrations, solution pH and reaction time on the adsorption capacity were investigated. The adsorption kinetics and isothermal data of ZIF-8 and KCC-1@ZIF-8 fitted well with pseudo-second-order and Langmuir isotherm models. The results of adsorption thermodynamics show that the adsorption process is spontaneous and endothermic. KCC-1@ZIF-8 exhibited a very high adsorption capacity (751.46 mg g−1) at an initial TC hydrochloride concentration of 80 mg L−1 in an aqueous solution at 301.15 K, and the value was higher than that of ZIF-8 (549.80 mg g−1) under the same conditions. KCC-1 exhibited a relatively lower capacity (37.860 mg g−1). Based on these findings, KCC-1@ZIF-8 was considered a promising adsorbent for the treatment of wastewater contaminated with TC hydrochloride. Additionally, the composite material, when combined with high-performance liquid chromatography (HPLC), could be used as a solid-phase extraction adsorbent for the adsorption of TC hydrochloride in animal foodstuff samples. The calibration curves showed a linear range of 20–500 μg L−1, and the recovery rate ranged from 85.216% to 90.717%. No one has made adsorbents with this new structure before, and KCC-1@ZIF-8 possessed excellent adsorption properties, which make it a potential candidate for environmental remediation and analytical applications involving TC hydrochloride.
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PubMed
高影响因子
Scientific Reports
·
2025
·Vol. 15
·期 1
·1-20
·
IF 3.9
Ye Ting,Yang Ruiquan,He Shumao,Li Jiahui,Liu Yi,Li Can,Luo Heng
The study investigates the synergistic endocrine disruption and cellular toxicity resulting from co-exposure to polyethylene microplastics (PE-MPs) and bisphenol A (BPA) in zebrafish and MLTC-1 cells. Previous research has extensively examined the individual effects of PE-MPs and BPA on endocrine systems and cellular health. However, the specific interactions and combined toxicological impacts of these two common environmental pollutants remain underexplored, particularly in terms of their synergistic effects on endocrine pathways and cellular viability. To fill this knowledge gap, we characterized PE-MPs using scanning electron microscopy and Raman spectrometry and exposed MLTC-1 cells to PE-MPs, BPA, or combinations of both. The results showed that co-exposure to 100 µg/mL PE-MPs and 100–150 µmol/L BPA for 48 h significantly decreased cell viability, increased apoptosis rates, induced G2/M cell cycle arrest, reduced mitochondrial membrane potential, and altered the transcriptional expression of genes related to steroidogenesis. Specifically, co-exposure upregulated the Ar while downregulating Lhr and 3β-Hsd , with these effects being more pronounced than those observed with single exposures. In a complementary in vivo study, adult zebrafish were exposed to environmentally relevant concentrations of PE-MPs (1 mg/L) and BPA (1.5 µg/L) for 28 days. This co-exposure resulted in significant increases in the GSI and alterations in the gene expression associated with the HPG axis. In male zebrafish brains, genes such as Gnrh2 , Esr1 , and Ar were downregulated, while in female brains, Gnrh3 , Esr1 , and Ar also exhibited downregulation. In male testes, Star , Cyp11a1 , and Hsd11b2 were upregulated, whereas Cyp19a1a , Hsd3b , Hsd20b , and Hsd17b3 were downregulated. In contrast, female ovaries showed upregulation of Cyp11a1 , Cyp17 , Cyp11b , Hsd3b , Hsd20b , and Hsd17b3 , while Cyp19a1a was downregulated, indicating a sex-specific endocrine disruption. Overall, the findings reveal that co-exposure to PE-MPs and BPA induces synergistic toxic effects both in vitro and in vivo, which underscores the importance of studying the effects of combined pollutants to better assess environmental health risks.
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高影响因子
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
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2024
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IF 4.1
Liwen Zhang,Luyao Xi,Shuyu He,Huizi Wen,Shanyi Tan,Shaohua Chen
Bioremediation has garnered considerable interest due to its advantages of economy and no secondary pollution. However, the direct electron transfer rate between microorganisms and Cr(VI) is low. The bioreduction of Cr(VI) by Shewanella oneidensis MR-1 ( S. oneidensis ) in the presence of formylmethylflavin (FMF) was conducted to understand how FMF mediated the extracellular electron transfer process to improve Cr(VI) removal. In this study, FMF was firstly synthesized by modifing RF to increase its solubility and redox activity. The findings indicate that S. oneidensis /FMF exhibited better Cr(VI) removal performance compared to that of S. oneidensis . Under optimum conditions, 40 mg/L Cr(VI) could be completely removed by S. oneidensis /FMF within 120 h, while only 48.6% of Cr(VI) was removed by S. oneidensis , and the first order rate constant (k) for the Cr(VI) elimination by S. oneidensis /FMF (0.033 h −1 ) was about 4.1-fold greater than that of S. oneidensis (0.008 h −1 ). Moreover, the removal of Cr(VI) by S. oneidensis /FMF were dominated by reduction, and supplemented by adsorption and complexation. FMF enhance the extracellular electron transfer rate (EETR) was confirmed by electrochemical cyclic voltammetry (CV) and linear scanning voltammetry (LSV) experiments. This study emphasizes the potential important role of FMF in environmental bioremediation.
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高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2024
·
IF 4
Meng Ye,Hongying Hou,Xianxi Liu,Zhaowei Sun,Xiaohua Yu,Ju Rong
With the development of the consumer society, low cost and high performance supercapacitors are being pursued. To realize the practical supercapacitors, developing the cheap and highly capacitive electrode is the most essential. However, it is a harsh challenge to achieve this target based on single-component electrode. Herein, a series of inexpensive ternary-metal-sulfides, 2MnS/Cu 2 S/ x ZnS/C ( x = 0, 0.5, 1, 2, 3) are synthesized by hydrothermal reaction and the subsequent calcination with expired manganese/copper gluconates as the raw materials for the electrode in the pseudocapacitors. Furthermore, the effect of ZnS's content on the electrochemical properties of the ternary composites is also investigated. Specially, the optimal 2MnS/Cu 2 S/xZnS/C( x = 1) can output a specific capacitance of 1608 F/g at 1 A/g in the three-electrode system, while the 2MnS/Cu 2 S/xZnS/C||AC( x = 1) asymmetric supercapacitor can deliver a specific capacitance of 194 F/g at 1 A/g with the desirable energy density (800 W/kg) and power density (70.9 Wh/kg), higher than those of other samples. Especially, even after 2000 cycles at 5.0 A/g, the 2MnS/Cu 2 S/xZnS/C||AC( x = 1) asymmetric supercapacitor also delivers the reversible specific capacitance of 103 F/g with high capacitance retention of 97.0 %, indicating high cycling stability. The outstanding performances of the optimal 2MnS/Cu 2 S/xZnS/C( x = 1) may be attributed to the bridge-effect of ZnS component, which makes up for the low conductivity of MnS component and the low capacitance of Cu 2 S component, thus achieving the best synergistic effect of ternary metal sulfide 2MnS/Cu 2 S/xZnS/C( x = 1) .
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CNS Neuroscience & Therapeutics
·
2024
·
IF 4.8
Mingyan Wang,Xin Wei,Yugai Jia,Chaonan Wang,Xinliu Wang,Xin Zhang,Depei Li,Yuanyuan Wang,Yonggang Gao
Background Depression is a serious mental disorder and the most prevalent cause of disability and suicide worldwide. Chronic unpredictable mild stress (CUMS) can lead to a significant acceleration of depression development. Quercetin (Que) is a flavonoid compound with a wide range of pharmacological effects. Recent studies have shown that quercetin can improve CUMS‐induced depression‐like behavior, but the mechanism of its improvement is still unclear. α2δ‐1 is a regulatory subunit of voltage‐gated calcium channel, which can interact with N‐methyl‐D‐aspartate receptor (NMDAR) to form a complex. Objective In this study, we found that Que could inhibit the increase of α2δ‐1 and NMDAR expression in rat hypothalamus induced by CUMS. In pain, chronic hypertension and other studies have shown that α2δ‐1 interacts with the NMDAR to form a complex, which subsequently affects the expression level of NMDAR. Consequently, the present study aimed to investigate the antidepressant effect of Que in vivo and in vitro and to explore its mechanism of action in terms of the interaction between α2δ‐1 and NMDAR. Methods Rats were randomly exposed to two stressors every day for 4 weeks to establish a CUMS rat model, then sucrose preference test (SPT), forced swimming test (FST), tail suspension test (TST), and open field test (OFT) were performed to detect the behavior of CUMS rats, so as to evaluate whether the CUMS rat model was successfully established and the improvement effect of Que on CUMS‐induced depression‐like behavior in rats. Experimental techniques such as serum enzyme‐linked immunosorbent assay (ELISA), immunofluorescence, Western blot, and co‐immunoprecipitation, as well as in vitro experiments, were used to investigate the mechanisms by which Que exerts its antidepressant effects. Results Behavioral and ELISA test results showed that Que could produce a reduction in the excitability of the hypothalamic–pituitary–adrenal (HPA) axis in CUMS rats and lead to significant improvements in their depressive behavior. Western blot, immunofluorescence, and co‐immunoprecipitation experiments showed that Que produced a decrease in NMDAR1 and α2δ‐1 expression levels and interfered with α2δ‐1 and NMDAR1 binding. In addition, the neural regulation mechanism of Que on antidepressant effect in PC12 cells knocked out α2δ‐1 gene was further verified. Cellular experiments demonstrated that Que led to a reversal of up‐regulation of NMDAR1 and α2δ‐1 expression levels in corticosterone‐injured PC12 cells, while Que had no effects on NMDAR1 expression in PC12 cells with the α2δ‐1 gene knockout. Conclusions Que has a good antidepressant effect and can significantly improve the depression‐like behavior caused by CUMS. It exerts antidepressant effects by inhibiting the expression level of α2δ‐1, interfering with the interaction between α2δ‐1 and NMDAR, and then reducing the excitability of the HPA axis.
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Tengfei Liu,Yuanshuang Liu,Dingrong Qu,Shougang Chen,Wenwu Chen,Lei Han,Zhigang Qiu,Linqi Zhu,Mindong Chen
COF LZU-1 has the characteristics of a porous structure, a large specific surface area , and good chemical stability. In recent decades, extensive research has been conducted on its use as a nanomaterial for drug loading and separation. Here, we report a new corrosion inhibitor encapsulated nanostructure (LZU-1 @BTA). We synthesized LZU-1 via a hydrothermal method and loaded benzotriazole (BTA) corrosion inhibitor into LZU-1. The results show that loaded BTA can achieve effective pH-responsive release under acidic and alkaline conditions. The amino group present in the LZU-1 molecule can cross-link with epoxy resin , and its compatibility allows for good dispersion in epoxy resin without any further modification. The LZU-1 @BTA modified epoxy coating has shown remarkable anti-corrosion properties and excellent self-healing capabilities, which have been evaluated through various techniques such as potentiodynamic polarization curves, electrochemical impedance spectroscopy (EIS), local electrochemical impedance spectroscopy (LEIS), scanning Kelvin probe (SKP) and salt spray testing. The high-quality dispersion of LZU-1 @BTA in the resin, the high cross-linking density, and the pH-responsive release of BTA in the epoxy resin are some of the key factors that contribute to the excellent anti-corrosion performance of the epoxy resin composite coating . This research has opened up new possibilities for designing anti-corrosion coatings with significantly better corrosion resistance .
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危险品化学品经营许可证（带存储）