APPLIED SURFACE SCIENCE
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2019
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IF 5.155
Meiting Song,Yuhang Wu,Guopeng Zheng,Chunfang Du,Yiguo Su
Z -scheme g-C 3 N 4 /Au/BiVO 4 photocatalyst has been prepared successfully by assembling gold nanoparticles on the interface of super-thin porous g-C 3 N 4 and BiVO 4 , which exhibits outstanding photocatalytic performance toward hydrogen evolution and durable stability in the absence of cocatalyst. The highest photocatalytic hydrogen production rate of g-C 3 N 4 /Au/BiVO 4 was about 410.0 μmol g −1 h −1 , which largely beyond that obtained of g-C 3 N 4 /BiVO 4 (23.3 μmol g −1 h −1 ), Au/g-C 3 N 4 (244.6 μmol g −1 h −1 ) and pristine g-C 3 N 4 (2.2 μmol g −1 h −1 ). The optimal apparent quantum efficiency was counted to be 6.8% at λ = 420 nm and 1.1% at λ = 600 nm. Moreover, the photocatalytic property of g-C 3 N 4 /Au/BiVO 4 could remain unchanged almost with 50 h in 5 cycles. The improvement of photocatalytic H 2 yield is attributed to the result of rapid separation of photogenic carriers in space and surface plasmon resonance effect of Au nanoparticles. In combination of photoelectrochemical measurement, active species capture experiment and electron paramagnetic resonance spectra, the underlying mechanism was illuminated. The pathway of charge carrier migration between semiconductor photocatalysts could be changed to Z-system through Au as an electron intermediate, which could not only benefit to maintain outstanding redox capability but also help to accelerate photo-generated carrier separation, and thus improve the photocatalytic activity .
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ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Xilin Bai,Suying Xu,Leyu Wang
The sensitive and selective detection of hydrogen sulfide is of great importance due to its crucial role in pathological and physiological processes. Herein, we report a novel fluorescent platform, AuNCs@GC, for selective detection of hydrogen sulfide in living cells by impregnating the Au nanoclusters (AuNCs) into a biocompatible cationic polymer matrix, glycol-chitosan (GC) nanogel. The confinement effect significantly increased the emissive Au(I) units, resulting in a 6-fold enhancement of quantum yield (from 6.38% to 36.42%). In addition, the prepared positively charged AuNCs@GC nanogel exhibits excellent selectivity and improved sensitivity to aqueous sulfides. Moreover, the as-fabricated AuNCs@GC showed very good biocompatibility and super fluorescence stability across the full pH range and good salt tolerance, which demonstrated excellent adaptability toward intracellular sulfide imaging.
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PubMed
高影响因子
TALANTA
·
2018
·
IF 4.244
Lingxian Ye,Guangying Zhao,Wenchao Dou
A sensitive Point-of-Care Testing (POCT) with Au-Pt bimetallic nanoparticles (Au@Pt) functionalized silica nanoparticle (SiO 2 NPs) and Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 NPs) was designed for the quantitative detection of Escherichia coli O157:H7 ( E. coli O157:H7). The poly-(4-styrenesulfonic acid- co -maleic acid) (PSSMA) as a negatively charged polyelectrolyte can be easily coated on surface of the amino group modified SiO 2 NPs via electrostatic force . PSSMA is also a good stabilizer for water-soluble bimetallic nanostructures . The PSSMA is first time used as a “bridge” to connect the negative charge Au@Pt NPs to the SiO 2 NPs, forming Au@Pt/SiO 2 NPs. Antibody and invertase conjugated Au@Pt/SiO 2 NPs (denoted as Ab/invertase-Au@Pt/SiO 2 NPs) were used as signal labels. Monoclonal antibody against E. coli O157:H7 (Ab) functionalized magnetic nanoparticles (denoted as Ab-Fe 3 O 4 @SiO 2 NPs) were used to enrich and capture the E. coli O157:H7 in positive sample. The immunosensing platform also composed of a personal glucometer (PGM) using for signal readout. Based on this sandwich-type immunoassay , the invertase in the final formed sandwich immunocomplex catalyzed the hydrolysis of sucrose to produce a large amount of glucose for quantitative readout by the PGM. Under optimal conditions, a linear relationship between the glucose concentration and the logarithm of E. coli O157:H7 concentration was obtained in the concentration range from 3.5 × 10 2 to 3.5 × 10 8 CFU mL −1 with a detection limit of 1.83 × 10 2 CFU mL −1 (3σ). This method was used to detect E. coli O157:H7 in spiked milk samples, indicating its potential practical application. This protocol can be applied in various fields of study.
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MATERIALS CHEMISTRY AND PHYSICS
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2018
·
IF 2.21
Zhiming Zhang,Tingting Li,Yuqing Li,Li Yan,Libao An
Novel thiolation poly (phthalazinone ether ketone) (PPEK-SH) nanofibrous membrane (NFM) was successfully fabricated via grafting and electrospinning. The PPEK-SH NFM with high glass transition temperature (324.4 °C), robust tensile strength (12.48 MPa), high porosity (89.5%) and superior chemical resistance was employed as support of Au nanoparticles (NPs) for preparing electrocatalyst . Au NPs were deposited on the NFM via electroless plating and characterized by SEM, EDX , TEM and XRD . The as-prepared Au/PPEK-SH NFM inherited the excellent properties of PPEK-SH NFM and good conductivity of Au, thereby was successfully used as a free-standing electrocatalyst without resorting to any conductive support. The free-standing NFM exhibited excellent electrocatalytic activity towards glycerol oxidation with high oxidation peak of 74.2 mA cm −2 and low onset potential of −0.34 V. More importantly, benefiting from the strong chemical interaction between Au and -SH, Au/PPEK-SH NFM presented an incredible stability during the process of glycerol electrooxidation. Only 2.7% decrease of the peak current density was observed after 100 cycles of experiments, indicating that the free-standing electrocatalyst had great potential for long-term use. This work may provide a new approach for the development of stable free-standing electrocatalyst based on electrospun nanofibers in the application of direct alcohol fuel cells.
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NANO
·
2018
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IF 1.1
Yongfeng Gao,Yuanhui Feng,Lu Zhou,Lucia Petti,Zhe Wang,Jun Zhou,Shusen Xie,Jian Chen,Yanping Qing
Ultrasensitive detection of alpha-fetoprotein (AFP) is critical for the early diagnosis of liver cancer. In this work, a novel surface-enhanced Raman scattering (SERS)-based immunoassay complex has been successfully developed for the detection of AFP by using the Au-Ag alloy nanoparticals and the Ag/AgBr hybrid nanostructure. As the typical bimetal or metal/semiconductor plasmonic materials, besides the strong SERS enhancement characteristics, the Au-Ag alloy nanoparticals exhibit excellent monodispersity and the Ag/AgBr hybrid nanostructure demonstrates good stability. The experimental results show that the SERS-based immunoassay of AFP presents a low limit of detection of 1.86 fg/mL and a broad dynamic range from 2 fg/mL to 0.8 μ g/mL. Furthermore, the clinical applicability of the proposed SERS-based immunoassay has been assessed by the detection of AFP in the human serum samples of cancer patient and healthy person. The test data are consistent well with that of chemiluminescence immunoassay (CLIA) in the relative errors of − 8.82–8.06% and show better detection sensitivity. It reveals that the proposed immunoassay protocol is significant for giving insight into the design of ultrasensitive biosensor and the point-of-care testing of cancers.
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ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Qian Zhao,Jiafang Piao,Weipan Peng,Yang Wang,Bo Zhang,Xiaoqun Gong,Jin Chang
Identifying the microRNA (miRNA) expression level can provide critical information for early diagnosis of cancers or monitoring the cancer therapeutic efficacy. This paper focused on a kind of gold-nanoparticle-coated polystyrene microbeads (PS@Au microspheres)-based DNA probe as miRNA capture and duplex-specific nuclease (DSN) signal amplification platform based on an RGB value readout for detection of miRNAs. In virtue of the outstanding selectivity and simple experimental operation, 5′-fluorochrome-labeled molecular beacons (MBs) were immobilized on PS@Au microspheres via their 3′-thiol, in the wake of the fluorescence quenching by nanoparticle surface energy transfer (NSET). Target miRNAs were captured by the PS@Au microspheres-based DNA probe through DNA/RNA hybridization. DSN enzyme subsequently selectively cleaved the DNA to recycle the target miRNA and release of fluorophores, thereby triggering the signal amplification with more free fluorophores. The RGB value measurement enabled a detection limit of 50 fM, almost 4 orders of magnitude lower than PS@Au microspheres-based DNA probe detection without DSN. Meanwhile, by different encoding of dyes, miRNA-21 and miRNA-10b were simultaneously detected in the same sample. Considering the ability for quantitation, high sensitivity, and convenient merits, the PS@Au microspheres-based DNA probe and DSN signal amplification platform supplied valuable information for early diagnosis of cancers.
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高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2018
·Vol. 86
·期 3
·699-710
·
IF 1.745
Guo Jiuli,Han Qiuwan,Zhong Siyuan,Zhu Baolin,Huang Weiping,Zhang Shoumin
The M-modified TiO 2 nanotubes (NTs) (M = Ce, Ga, Co, Y, 2.0 wt%) were synthesized by combining sol-gel method with hydrothermal treatment, based on which gold was loaded by the deposition–precipitation approach. These catalysts were loaded with 1.5 wt% gold and calcined at 300 °C, and their catalytic performance was compared with Au/TiO 2 NTs in CO oxidation. TEM results manifested Au/M-TiO 2 NTs (M = Ce, Ga, Co, Y) had smaller gold nanoparticles than Au/TiO 2 NTs. Patterns of XPS revealed the presence of the strong interaction between gold and support in Au/M-TiO 2 NTs (M = Ce, Ga, Co, Y). Ce 4+ , Ga 3+ , Co 2+ , and Y 3+ ions were present as CeO 2 , Ga 2 O 3 , CoO, and Y 2 O 3 in Au/M-TiO 2 NTs (M = Ce, Ga, Co, Y), respectively. Based on O 2 -TPD studies, Au/M-TiO 2 NTs (M = Ce, Ga, Co, Y) provided new O 2 adsorption sites for the adsorption and activation of oxygen in CO oxidation. M (M = Ce, Ga, Co, Y) modifying performed the positive effect on CO oxidation activity and Au/Y-TiO 2 NTs showed the highest activity among these catalysts. Additionally, Au/Y-TiO 2 NTs also performed excellent high-temperature stability. It was likely that the strong interaction between gold and support created the small size of gold nanoparticles, large O 2 adsorption and plenty of defects, thereby enhancing the catalytic activity of Au/M-TiO 2 NTs (M = Ce, Ga, Co, Y).
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JOURNAL OF MOLECULAR LIQUIDS
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2018
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IF 4.513
Guo Lin,Shixing Wang,Libo Zhang,Tu Hu,Jinhui Peng,Song Cheng,Likang Fu
In this study, corn bract was modified with thiosemicarbazide (TSC-CCB) and used to selectively adsorb Au(III) from aqueous solutions. FT-IR spectroscopy, Scanning electron microscope and X-ray photoelectron spectroscopy were used to characterize TSC-CCB and investigate the adsorption mechanism. The results suggested that the maximum adsorption amount of Au(III) was 1470.22 mg/g at 25 °C with pH of 6.0. The adsorption isotherm and kinetic data were matched adequately with Langmuir model and pseudo-second-order model, respectively. Meanwhile, TSC-CCB presented a good selectivity for Au(III) from the competitive ions. The ion exchange and chelation between Au(III) and S/N groups played an important role in the enhancement of the adsorption capacity. The regeneration experiments suggested that the TSC-CCB retained high adsorption efficiency after three cycles. TSC-CCB was a promising adsorbent for recovery Au(III) from wastewater in the view of sustainability.
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高影响因子
APPLIED SURFACE SCIENCE
·
2018
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IF 4.439
Yayuan Li,Shubo Cao,Ang Zhang,Chen Zhang,Ting Qu,Yongbin Zhao,Aihua Chen
It is of great importance to extend the UV response of anatase TiO 2 into the visible light range for the practical applications. Here, a facile rout to carbon and nitrogen co-doped, Au loaded bowl-like TiO 2 nanostructures with tunable size are proposed by using self-assembled polystyrene- block -poly(4-vinylpyridine) (PS- b -P4VP) block copolymer (BCP) spherical micelles as templates. Amphiphilic PS- b -P4VP self-assembles to form PS@P4VP core–shell spherical micelles with P4VP as the out layer in an evaporable mixed solvents of ethanol/tetrahydrofuran (THF). The size of uniform PS@P4VP spherical micelles can be precisely tuned in the range of a few nm to several hundred nm by controlling the molecular composition of the BCPs. Bowl-like TiO 2 nanostructures with a replicate size loaded with highly dispersed Au nanoparticles (NPs) of ∼5 nm in diameter are fabricated from these spherical micelles because of strong complex ability of pyridine groups. PS- b -P4VP provides carbon and nitrogen sources to dope the resulting samples simultaneously. The special carbon and nitrogen co-doped bowl-like Au/TiO 2 nanostructures exhibit much higher photocatalytic activity in the photodegradation of rhodamine B (RhB) compared to Au/P25 under visible light irradiation. Furthermore, the photocatalytic activity is significantly influenced by the BCP molecular composition due to different surface area and loading capacity of the resulting samples. This study provides a facile way to synthesize multi-element doped hollow or bowl-like nanoparticles with tunable size in the nanometer range which have potential application at photocatalysis, oxygen reduction reaction, etc.
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Oncology Letters
·
2018
·Vol. 15
·期 5
·8079-8087
·
IF 1.664
Daren Liu,Xiaowen Li,Changlei Chen,Chao Li,Chuanbiao Zhou,Weidong Zhang,Jiangang Zhao,Jie Fan,Kai Cheng,Li Chen
Gastric cancer is the fourth most common malignancy globally. In order to decrease the dosage and side effects of conventional chemotherapy, and achieve improved benefits from molecular targeted therapy, novel drug delivery systems were developed in the present study. Oxaliplatin‑Au‑Fe3O4‑Herceptin® acts as a dual‑functional nanoparticles (NPs) conjugate and possesses the capability of human epithelial growth factor receptor 2 (HER2) targeting and oxaliplatin delivery. The 8‑20 nm Au‑Fe3O4 were synthesized by decomposing iron pentacarbonyl on the surfaces of Au NPs in the presence of oleic acid and oleylamine. Following being coated with polyethylene glycol, the NPs possessed a ζ‑potential of 13.8±1.6 mV and were demonstrated to exhibit no cytotoxicity when Fe concentration is <100 µg/ml via an MTS assay. Mass spectrometry analysis detected a peak at m/z 148,000, and Nuclear Magnetic Resonance indicated peaks at δ 3.51 (8.00H, s, 3‑H), 2.97‑3.02 (3.80H, t, 2‑H) and 2.72‑2.76 (3.72H, t, 1‑H) following successful loading with Herceptin and oxaliplatin probes. A drug release assay via dialysis cassettes demonstrated that 25% of the oxaliplatin was released at pH 8.0, however >58% was released at pH 6.0 following 4 h incubation, indicating its pH‑dependent release characteristic. The active targeting feature of oxaliplatin‑Au‑Fe3O4‑Herceptin was verified in a subcutaneous xenograft mouse model containing SGC‑7901 cells via detecting aggregated low intensity in T2‑weighted magnetic resonance imaging, which was further confirmed by immunohistochemistry. Therefore, oxaliplatin‑Au‑Fe3O4‑Herceptin is a promising multifunctional platform for simultaneous magnetic traceable and HER2 targeted chemotherapy for gastric cancer.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2018
·Vol. 28
·期 34
·1802021
·
IF 13.325
Rui Yan,Yang Zhao,Hong Yang,Xiao-Jing Kang,Chao Wang,Li-Li Wen,Zhen-Da Lu
Metal–organic frameworks (MOFs) hold great promise as porous matrixes for the incorporation of Au nanoparticles (NPs) because of their rationally designed framework structures. Unfortunately, the as-synthesized bulk MOFs usually vary in the range of micrometer or sub-micrometer size, rendering extremely longer molecular diffusion distance of chemical species. 2D MOF nanosheets with extended lateral dimensions and nanometer thickness are expected to implement fast kinetics and effectively lower mass-transfer barriers during embedding Au NPs process and sequential catalytic reactions. In this study, a novel 2D nanosheet of mixed-ligand Ni(II) MOF (referred to NMOF-Ni ) is successfully fabricated. With the merits of well-defined micropores and functional oxygen-decorated inner walls, the incorporation of quite monodisperse ultrasmall Au nanoparticles of around 1 nm into NMOF-Ni has been achieved for the first time. The resulting nanocomposites exhibit remarkable catalytic performance and good size selectivity toward aqueous reduction reactions of nitrophenol, taking advantage of ultrasmall Au and 2D nanosheet nature, as well as the intact microporosity of host matrix. The present encouraging findings might shed light on new ways to develop high-performance heterogeneous catalysts by using of 2D MOF nanosheets with functional cavities as hosts for homogeneous distribution of ultrasmall Au NPs.
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JOURNAL OF MATERIALS SCIENCE
·
2018
·Vol. 53
·期 23
·15895-15906
·
IF 2.993
Sun Li,Lv Pengcheng,Li Haonan,Wang Fa,Su Wenxian,Zhang Lixin
Abstract The green and controllable synthesis of Au–Ag alloy nanoparticles (NPs) in one-pot has been a challenge in nanotechnology. Here, the soluble starch was employed as a reducing and capping agent to synthesize stable Au–Ag alloy NPs without using any toxic agent. The surface plasmon resonance wavelength and the composition of Au–Ag alloy NPs could be continuously adjusted only by the synthesis time in one-pot. Au–Ag alloy NPs were characterized by means of various techniques. It could be found as-prepared NPs were quasi-spherical with a small average size and a face-centered cubic polycrystalline structure. The above green synthesis method, facile, efficient and eco-friendly, can be extended to the controllable synthesis of other bimetallic NPs. Obtained Au–Ag alloy NPs exhibited a superior photocatalytic activity and stability for the 4-nitrophenol (4-NP) degradation due to abundance hydroxyl groups of the soluble starch and the synergistic effect between Au and Ag elements. The rate constant of 4-NP degradation could be linearly tuned by the composition of Au–Ag alloy NPs and their synthesis time besides their addition amount. The above methods to control the rate constant provide promising routes for other photocatalytic reactions using bimetallic NPs as photocatalysts. Graphical Abstract
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危险品化学品经营许可证（带存储）