ACS Photonics
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2026
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IF 6.7
Yan Yang,Haiqiang Huang,Lei Liu,Qiuhong Tan,Yifei Huang,Lujun Yang,Hui Zhang,Xuejin Zhang,Feng Song,Yingkai Liu
Two-dimensional (2D) Ruddlesden–Popper perovskite phenylethylammonium lead iodide ((PEA)2PbI4) possesses potential photoelectronic properties and is considered to be an ideal material for photodetectors. However, single devices commonly suffer from low responsivity, slow response speed, and narrow detection range, which hinder their applications in imaging, communications, and artificial intelligence (AI). In this work, high-quality 2D (PEA)2PbI4 tetragons (TTs) were synthesized via a unique liquid–air interface floating method and integrated with cadmium selenide (CdSe) nanobelts (NBs) to construct a novel hybrid heterojunction photodetector. It confirms that the formation of type-II band alignment at the heterointerface enables efficient interfacial charge transfer. Notably, the (PEA)2PbI4/CdSe heterojunction hybrid device exhibits exceptional performance under 450 and 682 nm monochromatic illumination: extremely high responsivity (R) (2.80 × 103 and 6.39 × 103 A/W), excellent detectivity (D*) (4.09 × 1013 and 9.32 × 1013 Jones), large external quantum efficiency (EQE) (7.74 × 105% and 1.16 × 106%), and remarkable Ion/Ioff ratio (3.60 × 105 and 8.66 × 105), as well as fast response speeds (rise/decay time: 108/265 μs and 86/196 μs). Furthermore, the hybrid device overcomes the intrinsic bandgap limitation of (PEA)2PbI4, extending its photoresponse to cover nearly the entire visible spectrum and demonstrating reliable imaging capability. This study provides an innovative strategy for developing high-performance photodetectors with significant practical application potential.
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ACS Nano
·
2026
·
IF 16
Kexin Man,Zhen-Jie Yu,Hao-Nan Li,Chao Zhang,Zhi-Kang Xu
Hydrogels featuring abundant network chemistry and tailorable pore structure have emerged as appealing membrane materials for numerous fields including ion sieving, gas separation, and osmotic energy harvesting. Nevertheless, current hydrogel membranes suffer from high transport resistance and inferior selectivity, owing to the inability of conventional thermal-initiated and photoinitiated bulky gelation methods to reduce their micrometer-scale thickness and pore sizes. Herein, we discover a versatile confined gelation platform to elaborate ultrathin lamellar hydrogel membranes (LHMs) using two-dimensional photothermal nanosheets as triggers to replace conventional small-molecule thermal initiators and photoinitiators. The LHMs are fabricated by manipulating the assembly of photothermal nanosheets within hydrogel precursors into a thickness-tunable lamellar skeleton with subnanometer interlayer spacing on the surface of porous substrates that harness their size screening ability to reject nanosheets for assembly, followed by a photothermal-triggered confined gelation only occurring within this lamellar skeleton. This approach enables the manufacturing of large-scale and uniform LHMs with superstable subnanochannels and ultrathin thickness as low as 50 nm, which is about 3 orders of magnitude lower than that of conventional counterparts. By customizing hydrogel network chemistry, our LHMs can be applied for gas separation with an extraordinary CO2/N2 selectivity of 175 as well as harvesting osmotic energy with an impressive maximum power density of 6.87 W/m2 even under long-term services.
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ANALYTICAL CHEMISTRY
·
2026
·
IF 6.7
Kun Wang,Wanli Wang,Yufeng Hu,Xiaoyang Li,Haoyu Yu,Xin Xia,Tianhan Kai,Mei Wen
Staphylococcus aureus (SA) is a predominant foodborne pathogen, frequently associated with nutrient-rich matrices. However, rapid and ultrasensitive detection of SA in complex food samples remains a formidable challenge. In this work, we developed a relay biosensing system for detecting SA-16S rDNA that combines a magnetic bead-anchored APE1 DNA walker with an asymmetric CRISPR/Cas12a system. The magnetic bead-anchored DNA walker enables efficient separation of SA-targets from complex food matrices, while generating abundant activators through APE1-mediated catalytic cleavage. Employing spatially decoupled reactions with differential crRNAs, the asymmetric Cas12a system achieves programmable cascade amplification. Dual-mode fluorescence/electrochemical readout supports both laboratory analysis and on-site detection. The system demonstrates exceptional sensitivity, capable of detecting trace amounts of SA-16S rDNA (7.5 aM by fluorescence, 1.0 fM by electrochemistry) and SA (4 CFU/mL by fluorescence, 34 CFU/mL by electrochemistry). Overall, this work provides a modular and programmable biosensing strategy for bacterial identification, thereby facilitating advanced nucleic acid analysis within complex biological matrices.
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INORGANIC CHEMISTRY
·
2026
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IF 4.7
Fei Chen,Sisi Wu,Jian Kuang,Sijia Xiang,Shenghu Wang,Siming Yuan,Kaiming Cao,Lu Yu,Wenming Yang,Liqin Tang,Yangzhong Liu
Human copper transporter 1 (hCtr1) is a transport protein essential for cellular copper uptake and homeostasis, yet excess copper influx is toxic to cells. Currently, no inhibitors of hCtr1 are available to modulate intracellular copper levels. Here, we discovered that the natural phenolic compound rosmarinic acid (RA), as a moderate-strength copper chelator, can directly interact with hCtr1 and inhibit its copper-transport function. RA binds to the N-terminal copper-binding domain of hCtr1, lowering the Cu(II)-binding affinity of hCtr1. More crucially, RA and hCtr1 form a ternary complex with Cu(II) ions (RA/Cu/hCtr1). Cellular assays indicated that RA inhibited the copper-mediated membrane interaction of the hCtr1 N-terminal copper-binding domain, a crucial step in triggering cellular copper internalization. Functional assays showed that RA significantly inhibits hCtr1-mediated copper uptake under high copper conditions, hence effectively alleviating cellular copper overload and attenuating copper-induced cytotoxicity. Notably, the moderate copper-binding affinity of RA minimizes adverse effects while modulating the cellular copper levels. This work identifies RA as a promising lead compound for modulating copper-related pathologies and provides a strategy for regulating intracellular copper homeostasis by targeting hCtr1.
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ACS Applied Materials & Interfaces
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2026
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IF 8.2
Hui Xin,Rongtan Li,Xuyuan Huang,Dan Li,Lan Wu,Xiandeng Hou
The coordinatively unsaturated metal species of metal oxides always play important roles in both constructing oxide-based catalysts and catalyzing some reactions. However, it is a challenge to tune its surface density and stability due to the uncontrolled reduction. Herein, we deposit MoO3 onto different oxides via the simple dry combustion method and find that the host oxides affect formation of coordinatively unsaturated Mo species through the oxide–support interaction, thus strongly altering their reverse water–gas shift activity. The strong oxide–support interaction lowers the reduction temperature of the amorphous oligomeric MoOx species on m-ZrO2 and a-TiO2 supports, generating high surface content of coordinatively unsaturated MoO2-x species with high stability, compared with those on CeO2, γ-Al2O3, and SiO2 supports. Consequently, MoO3/m-ZrO2 displays the highest CO2 reaction rate through the formate reaction pathway, i.e., 19.2 mmolCO2·gcatal–1·h–1, followed by MoO3/a-TiO2 (12.8 mmolCO2·gcatal–1·h–1), which are 21 and 14 times higher than that of MoO3, respectively. Moreover, the MoO3/m-ZrO2 and MoO3/a-TiO2 catalysts also display good stability during the 60 h reaction due to the strong interface bonding. This work provides a way to mediate catalytic performance of metal oxide catalysts through the oxide–support interaction.
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Journal of Physical Chemistry C
·
2026
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IF 3.2
Yaoqi Wei,Ziwei Lu,Fengyun Zhang,Ying Chen,Kuangcheng Zhang,Wenting Qiu,Huanhuan Zhang,Shujia Wu,Xiangfei Liang
The efficiency of electrochemical water splitting is predominantly governed by two central processes: the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER). While noble metal catalysts like Pt/C show exceptional HER performance, their high-cost limits widespread use. The exceptionally high surface areas and tunable porosity of metal–organic frameworks (MOFs) render them highly promising for electrocatalytic applications. However, challenges in scalable synthesis and stability remain between research and industrial application. Designing efficient non-noble metal-based alternatives is crucial. Herein, we design a molecularly engineered 2D MOF system constructed from hierarchical copper–organic coordination networks. The CuBTC framework was employed as a bifunctional electrode for overall water splitting. At a current density of 10 mA cm–2, the cell voltage required was 1.75 V, demonstrating promising electrocatalytic performance and stability. The overpotentials for the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) were measured as 268 and 165 mV, respectively. This work offers an innovative strategy for designing MOF-based electrocatalysts to advance water electrolysis efficiency.
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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2026
·Vol. 123
·期 2
·e2521306123
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IF 9.1
Yuxi Zhao,Man Tong,Li Tian,Genming Luo,Ping Li,Haijun Song,Zhong-qiang Chen,Shucheng Xie,Andreas Kappler,Songhu Yuan
The great phytoplanktonic shift from green to red plastid lineage dominance in the early Mesozoic marks a primary producer revolution in marine ecosystems, facilitating the rise of modern ecosystems and impacting global carbon cycling and energy flows. The causes driving this evolutionary transition have been attributed to the changes in essential nutrients and the environmental crises of the Permian–Triassic mass extinction. Nonetheless, the underlying mechanisms driving this transition remain poorly understood. Here, we integrated culture experiments, molecular and physiological analyses, big data analysis, and phylogenomic dating analyses to uncover how environmental stresses influence algal physiology, thereby altering their evolutionary trajectories. We find that environmental and endogenous reactive oxygen species (ROS) collaboratively shape phytoplanktonic responses. The structural characteristics of red lineage phytoplankton enhance resistance to environmental ROS, facilitating physiological strategies that minimize endogenous ROS accumulation, thereby driving more adaptive evolutionary trajectories under environmental stresses in the early Mesozoic. The alignment of the turnover in diversification dynamics between the two lineages with paleoenvironmental shifts that triggered increased ROS production supports the role of ROS in driving this evolutionary transition. Our findings highlight ROS as a key underlying factor driving phytoplankton evolution, providing predictive insights into major biota–environment coevolutions throughout Earth’s history.
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ACS Biomaterials Science & Engineering
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2026
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IF 5.5
Yansong Wang,Yichong He,Yuxun Wu,Enze Zhao,Hanwei Huang,Zhengbin Yan,Hainan Shen,Fenbo Ma,ShuaiShuai Cao,Bin Tang
Background: Polyetheretherketone (PEEK) is a promising alternative to titanium alloy for dental implants due to its bone-mimicking elastic modulus, which mitigates stress shielding. However, its bioinert nature limits osseointegration. Methods: We developed a novel PEEK variant, PEEK-chondroitin sulfate zinc (PEEK-CSZn), by chemically grafting zinc and chondroitin sulfate onto the PEEK surface. Material properties were characterized using SEM, FTIR, EDS, and ICP-MS. Anti-inflammatory, osteogenic, and angiogenic effects were evaluated in vitro using MC3T3-E1, HUVEC, and RAW264.7 cells and in vivo using a rabbit femur bone defect model. Results: Characterization confirmed successful CSZn integration. In vitro, PEEK-CSZn at 500 μg/mL enhanced the MC3T3-E1 cell proliferation. Osteogenic markers (OCN and Osterix) were upregulated by around 2.3- and 1.8-fold, respectively, in MC3T3-E1 cells (p < 0.05). Inflammatory markers (IL-6 and IL-12a) in RAW264.7 cells decreased by 23% and 49%, respectively (p < 0.05), while angiogenic markers (VEGF and CD31) in HUVECs increased by 2.2- and 2.8-fold (p < 0.05). In vivo, Micro-CT analysis revealed PEEK-CSZn increased bone volume fraction (BV/TV) and BMD compared to unmodified PEEK at 8 weeks postimplantation (p < 0.05). Conclusions: PEEK-CSZn exhibits trifunctional bioactivities, including anti-inflammatory, osteogenic, and angiogenic, and thus significantly enhances osseointegration, making it a promising material for advanced dental implant applications.
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JOURNAL OF MATERIALS SCIENCE
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2026
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IF 3.9
Yang Lanlan,Huang Dan,Liu Guoxiang,Wu Yihui
The urea oxidation reaction (UOR) has garnered significant attention as a promising alternative to the oxygen evolution reaction (OER) for water electrolysis, owing to its superior kinetic properties that enable enhanced hydrogen production efficiency. However, the practical deployment of UOR technology remains hindered by the persistent challenge of developing electrocatalysts that simultaneously achieve high activity, long-term operational stability, and cost-effectiveness. Herein, we report a facile, eco-friendly, one-step synthesis process to fabricate nickel–tin electrocatalyst (Ni–Sn) on Ni foam for catalyzing UOR via electrodeposition, using SnCl 2 ·2H 2 O and NiSO 4 ·6H 2 O as the Sn and Ni sources, respectively. Notably, the Ni–Sn electrocatalyst with a Ni/Sn ratio (90.39:8.61 at%) exhibits remarkable UOR activity, delivering a low potential of 1.493 V versus RHE to reach 10 mA·cm −2 , a small Tafel slope of 83.5 mV·dec −1 , and excellent stability with minimal decay after 100 h of continuous operation in alkaline urea electrolyte (1.0 M KOH + 0.33 M urea). The excellent activity of the Ni–Sn electrocatalyst for UOR benefits from the synergistic interaction between Ni and Sn, which modulates the electronic structure and accelerates charge transfer kinetics, thereby significantly enhancing reaction dynamics. Furthermore, the intrinsic superhydrophilicity of the Ni–Sn catalyst promotes efficient mass transport of reactants and products, contributing to its superior bifunctional catalytic performance for UOR.
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Science China-Chemistry
·
2026
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IF 9.7
Huang Chunmei,Pang Xuan,Li Fuming,Cao Shumei,Pan Shilie,Mutailipu Miriding
Nonlinear optical (NLO) and birefringent crystals are pivotal for advancing photonic technologies, enabling critical functions from laser frequency conversion to quantum information processing. To address the pressing need for miniaturized devices with enhanced optical anisotropy, we strategically select 5-hydroxy-2-pyridinecarboxylic acid (C 6 H 5 NO 3 ), a low-toxicity, cost-effective organic molecule featuring a pyridine-derived π -conjugated system marginally expanded beyond benzene, as NLO functional motif. This molecular design incorporates dual-functional OH/COOH groups that synergistically extend π -delocalization within the planar six-membered ring and provide two anionic states ([C 6 H 4 NO 3 ] − and [C 6 H 3 NO 3 ] 2− ), facilitating diverse supramolecular assemblies with alkali/alkalineearth metal ions. Through confined assembly optimization, we discovered a crystal Na 2 (C 6 H 3 NO 3 )·H 2 O, which achieves an excellent ultraviolet (UV) NLO performance: phase-matched second harmonic generation (SHG) intensity (14.0 × KH 2 PO 4 (KDP) at 1064 nm, the highest among planar mono-six-membered-ring systems), giant birefringence (0.487 at 546 nm), and a UV cutoff edge (321 nm). Multimodal analyses confirm the planar organic anion [C 6 H 3 NO 3 ] 2− as the origin of these exceptional optical responses, where ionic bonding and N–O/N layer confinement enforce optimal alignment.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2026
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IF 4.1
Yunlin Bai,Tianhe Li,Hao Chen,Yang Xu,Jiahao Ji,Guanghua Wei,Junfang Cheng
Developing efficient and durable oxygen reduction reaction (ORR) catalysts is critical for advancing proton exchange membrane fuel cells (PEMFCs). While Pt-based alloy catalysts exhibit enhanced ORR activity, their disordered nanostructures often compromise durability. In this work, a carbon-supported Pt 3 Cu alloy catalyst with a core-shell architecture (Pt 3 Cu@Pt/C) was synthesized via a controlled impregnation-reduction method followed by acid-washing to construct a Pt-rich shell. Comprehensive physicochemical characterizations confirmed the formation of a face-centered cubic (FCC) structure with a Pt 3 Cu core and a Pt-rich shell. Alloying with Cu was found to downshift the Pt d-band center, thereby optimizing the adsorption strength of oxygen intermediates. Electrochemical evaluations revealed that the Pt 3 Cu@Pt/C catalyst exhibited a mass activity (MA) of 0.37 A mg −1 and an electrochemical surface area (ECSA) of 89.43 m 2 g −1 , surpassing commercial Pt/C. Although the core-shell treatment slightly reduced ORR activity compared to untreated Pt 3 Cu/C, the Pt 3 Cu@Pt/C catalyst demonstrated exceptional durability, retaining >70% of its initial ECSA and showing only a 27% decay in MA after 30,000 accelerated stress test cycles, far outperforming both Pt 3 Cu/C and commercial Pt/C. Density functional theory (DFT) calculations revealed that the Pt shell increased Cu vacancy formation energy by 0.8 eV, effectively suppressing Cu dissolution and enhancing structural stability. This work highlights the synergistic electronic and geometric effects of core-shell nanostructures in balancing ORR activity and durability, providing insights for designing advanced Pt-based catalysts.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
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IF 8.5
Bo Yang,Hui Pan,Rui Ke,Haoyuan Li,Kai Liu,Jiahao Wang,Changyu Qu,Chao Ling,Yuan Huang
The oil pollution in aquatic ecosystems poses a serious threat to public health and ecological balance. In addressing this challenge, this investigation employed bacterial cellulose (BC) as the matrix material, through strategic incorporation of chemical cross-linking agents (Butane tetracarboxylic acid and graphene oxide) combined with freeze-drying technology and chemical vapor deposition (CVD) method to fabricate cross-linked BC (CBC) aerogels. Subsequent hydrophobic modification via chemical vapor deposition was implemented to optimize surface properties. Key findings revealed that the cross-linked composite aerogel demonstrated a homogeneous 3D lamellar architecture with negligible crystal precipitation, manifesting remarkable structural stability (linear shrinkage rate 5.88%) and ultrahigh porosity (99.9%) accompanied by minimal average pore diameter (1.9 nm). Enhanced thermal stability was evidenced by increased mass residual rate from 15.9% to 41.5% at 600 °C. The material maintained superior compression resilience through 10 compression cycles at 50% strain, preserving structural integrity in aqueous environments. Optimal hydrophobicity (contact angle 152°) was achieved after 3.5 h of vapor deposition, while remarkable adsorption capacities for various oils were recorded (45–204 g/g). Notably, the composite exhibited outstanding reusability, retaining 85.2% of ethanol adsorption capacity after 20 extraction cycles, and preserving 76.7% of paraffin oil adsorption capacity. These results collectively demonstrate the broad application prospects of this bio-based oil-absorbing material in oil-water separation technologies.
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