Nanoscale
·
2016
·Vol. 8
·期 9
·5089-5097
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IF 7.76
Abdul Hakeem,Fouzia Zahid,Ruixue Duan,Muhammad Asif,Tianchi Zhang,Zhenyu Zhang,Yong Cheng,Xiaoding Lou,Fan Xia
Herein, we design novel cellulose conjugated mesoporous silica nanoparticle (CLS-MSP) based nanotherapeutics for stimuli responsive intracellular doxorubicin (DOX) delivery. DOX molecules are entrapped in pores of the fabricated mesoporous silica nanoparticles (MSPs) while cellulose is used as an encapsulating material through esterification on the outlet of the pores of the MSPs to avoid premature DOX release under physiological conditions. In in vitro studies, stimuli responsive DOX release is successfully achieved from DOX loaded cellulose conjugated mesoporous silica nanoparticles (DOX/CLS-MSPs) by pH and cellulase triggers. Intracellular accumulation of DOX/CLS-MSPs in human liver cancer cells (HepG2 cells) is investigated through confocal microscope magnification. Cell viability of HepG2 cells is determined as the percentage of the cells incubated with DOX/CLS-MSPs compared with that of non-incubated cells through an MTT assay.
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PubMed
高影响因子
POLYMER BULLETIN
·
2016
·Vol. 73
·期 7
·2073-2085
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IF 1.371
Zhang Xuzhen,Ma Piming,Zhang Yong
Cellulose nanocrystal (CNC) was extracted from microcrystalline cellulose (MCC) and then surface modified by acetic anhydride to obtain acetylated CNC (ACNC). ACNC that has lower polarity than CNC was mixed with poly(butylene adipate- co -terephthalate) (PBAT) through melt blending to obtain composites. ACNC was uniformly dispersed in PBAT matrix as evidenced by scanning electron microscopy observation. Thermogravimetric analysis indicates the thermal stability of PBAT could be improved by the addition of either CNC or ACNC. In the rheological tests and dynamic mechanical analysis, PBAT/ACNC composites showed higher melt elasticity, complex viscosity, storage modulus and glass transition temperature than PBAT/CNC composites, indicating a stronger interfacial adhesion between ACNC and PBAT. As a result of the uniform dispersion of ACNC and strong interfacial adhesion between ACNC and PBAT, mechanical properties of PBAT/ACNC composites improve obviously. Good mechanical properties, high initial decomposition temperature and high glass transition temperature of PBAT/ACNC composites could contribute to the practical commercial utilization of PBAT.
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高影响因子
CARBOHYDRATE POLYMERS
·
2015
·
IF 4.074
Wei Yan,Chang Chen,Ling Wang,Dan Zhang,Ai-Jun Li,Zheng Yao,Li-Yi Shi
The emphasis of science and technology shifts toward environmentally friendly and sustainable resources and processes. Herein, we report a facile, one-pot and green synthesis of biomaterial-supported gold nanoparticles (AuNPs) with superior catalytic activity. Cellulose nanocrystal (CNC)-supported AuNPs were prepared by heating the aqueous mixture of HAuCl 4 , CNCs and polyethylene glycol, avoiding toxic chemicals, extreme condition and complicated procedure. The resultant CNC-supported AuNPs exhibited catalytic activities for the reduction of 4-nitrophenol by sodium borohydride. The maximum apparent rate constant reached 1.47 × 10 −2 s −1 , and the turnover frequency reached 641 h −1 . The superior catalytic performance can be ascribed to the large amount of highly dispersed AuNPs with few nanometers in size which are loaded on CNCs. About 90% of the AuNPs are smaller than 10 nm, and nearly 60% of the AuNPs are smaller than 5 nm. The synthesis is eco-friendly, facile and low-cost, thus has great potential for industrial and medical applications.
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2016
·
IF 2.76
Guohui Li,Kaiyue Sun,Dawei Li,Pengfei Lv,Qingqing Wang,Fenglin Huang,Qufu Wei
Bacterial cellulose-gold nanoparticles (BC-AuNPs) hybrid nanofibers were synthesized by in-situ chemical reduction. The obtained BC-AuNPs nanofibers were characterized by a series of analytical techniques. The results revealed that gold nanoparticles (AuNPs) were successfully deposited on the surfaces of bacterial cellulose nanofibers. Then, the as-prepared BC-AuNPs hybrid nanofibers were attached onto the electrode surface followed by adding a certain amount of laccase (Lac) and Nafion to construct novel a biosensing platform. The prepared electrochemical biosensor was employed to detect hydroquinone. The sensor showed excellent electrocatalysis towards dopamine with low detection limit (5.71 nM), and wide linear range (30–100 nM). Moreover, the biosensor also showed good repeatability, reproducibility, selectivity and stability and was successfully used in the detection of hydroquinone in lake water samples, thus providing a promising method for hydroquinone detection in water environments.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2017
·
IF 2.843
Xiaojuan Lei,Xuehai Dai,Sihui Long,Ning Cai,Zhaocheng Ma,Xiaogang Luo
Cellulose/metal hybrid macrogels were prepared by immobilizing uniformly dispersed thiolate-modified Fe2O3 nanoparticles into a cellulose matrix. The structure and properties of the hybrid macrogels were characterized using SEM, EDS, water contact angle, XRD, FTIR, XPS, and adsorption tests. The hybrid macrogels exhibited good stability, convenient operation, and high selectivity for trace phosphate removal, with a remaining phosphorus concentration of only 0.15 mg L–1 in 200 min (5 mg L–1 initial concentration). The influences of pH, ionic strength, and competitive anions were also investigated. The hybrid macrogels could be recovered by simple and rapid magnetic separation and regenerated in NaOH solution. During 5 cycles of the adsorption–elution–regeneration stability test, the hybrid macrogels still retained 80% adsorption capacity of trace phosphate. In this work, utilization of natural polymer was combined with green and sustainable technology to develop economically sustainable, eco-friendly, and cost-effective cellulose/metal hybrid macrogels for the application of trace phosphate removal from water.
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2017
·
IF 6.065
Xiao Wei,Ting Huang,Jing-hui Yang,Nan Zhang,Yong Wang,Zuo-wan Zhou
In this work, we developed a green synthesis method to prepare the hybrid aerogels containing graphene oxide (GO) and microcrystalline cellulose (MCC) using lithium bromide (LiBr) aqueous solution as the solvent, which insured the complete dissolution of MCC. The interaction between GO and MCC was investigated through different methods The results demonstrate that there is a strong interaction between GO and MCC molecules, which promotes the exfoliation of GO in the hybrid aerogels. The hybrid GO/MCC aerogels exhibit typical three dimensional porous structure and the pore morphology can be well adjusted by changing the content of GO. The adsorption ability of the hybrid aerogels was measured using methylene blue (MB) as an adsorbate. The results show that the adsorption ability of GO per unit mass is greatly enhanced compared with the pure GO aerogel, especially at relatively low GO content the adsorption amount of GO per unit mass is enhanced up to 2630 mg/g. Further results demonstrate that the hybrid GO/MCC aerogels still obey the pseudo-second-order adsorption model, which is similar to that of the pure GO aerogel. The mechanism for the amplified adsorption ability of GO in the hybrid GO/MCC aerogels is then analyzed.
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PubMed
高影响因子
CELLULOSE
·
2017
·Vol. 24
·期 12
·5327-5339
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IF 3.417
Gan Linhuo,Zhu Jundong,Lv Li
Acidic carbonaceous solids were synthesized from mass pine alkali lignin via hydrothermal carbonization followed by sulfonation. Hydrothermal carbonization of lignin in the presence of acrylic acid (LAHC-SO 3 H) provided many more carboxylic groups than that in the absence of acrylic acid, allowing subsequent sulfonation to produce a highly active and stable catalyst for cellulose hydrolysis in the [BMIM]Cl-H 2 O solvent system. The hydrochar and catalyst were characterized using field emission scanning electron microscopy, X-ray diffractometer, X-ray photoelectron spectroscopy, thermal gravimetric analysis, Fourier transform infrared spectrometer, Brunauer–Emmett–Teller and acid–base titration. Results showed that a high acid content of 5.48 mmol/g, including carboxylic group (2.85 mmol/g), phenolic hydroxyl group (1.05 mmol/g) and sulfonic acid group (1.58 mmol/g), contributed significantly to the highly efficient hydrolysis of cellulose. Further, it was found that addition of trace water in [BMIM]Cl was favorable to cellulose hydrolysis. The highest yield (75.4%) of total reducing sugar (TRS) obtained in [BMIM]Cl-H 2 O at a mass ratio of 100:1 was more than twice that (36.1%) achieved in [BMIM]Cl without water; the corresponding reaction conditions were 50 mg of microcrystalline cellulose, 30 mg of catalyst, 1.0 g of [BMIM]Cl, 10 mg of H 2 O, reaction temperature of 130 °C and reaction time of 2 h. Furthermore, the TRS yield with 5 cycles for LAHC-SO 3 H was higher than 68.1%, and the catalytic activity of catalyst could be fully recovered (74.0% of TRS yield) easily by regeneration.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
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2017
·Vol. 53
·期 2
·1568-1579
·
IF 2.599
Liang Miao,Zhang Guo,Feng Yajie,Li Ruili,Hou Pei,Zhang Junsong,Wang Jianmin
Facile and robust immobilization of metal nanoparticles onto porous supporting matrix is an important issue in heterogeneous catalysis. This study reports a facile procedure for the synthesis and immobilization of small catalytic active silver nanoparticles (AgNPs) on cellulose paper (CP), which possesses interconnected fibrous structure and can be employed as cost-effective supports. Amino groups were first introduced to CP, through a silane coupling technique, to provide stable anchoring centers for silver ions. Small-sized AgNPs without aggregation were facilely synthesized and stably immobilized onto the fiber surface of CP followed by NaBH 4 reduction. The as-prepared AgNPs incorporating composites exhibited excellent catalytic activity for the reduction of 4-nitrophenol. The rate constant of the catalytic reaction was calculated to be 1.46 × 10 −2 s −1 . More importantly, these amino-modified paper-based composite catalysts can be easily recovered and reused for at least six cycles due to their enhanced mechanical and catalytic stability.
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高影响因子
Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 38
·7876-7884
·
IF 4.543
Kaiwen Mou,Juanjuan Li,Yunyun Wang,Ruitao Cha,Xingyu Jiang
Nanocellulose materials have undergone rapid development in recent years as promising biomedical materials due to their excellent physical and biological properties, in particular their biocompatibility, biodegradability, and low cytotoxicity. In this study, we prepared 2,3-dialdehyde nanofibrillated cellulose (DANFC) by sodium periodate oxidation, which is a mild oxidation process. With increasing oxidation time, the antimicrobial activity of DANFC against both Staphylococcus aureus (S. aureus) and methicillin-resistant Staphylococcus aureus (MRSA) improved. DANFC also displays good biocompatibility with mammalian cells, and shows good blood compatibility. In addition, animal studies and histology results reveal that DANFC can accelerate wound healing and enhance the formation of blood vessels and epithelium.
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PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2016
·
IF 5.267
Xujuan Huang,Aiting Wang,Xu Xu,He Liu,Shibin Shang
We report on an efficient method for the formation of modified cellulose-based materials with enhanced hydrophobic properties, formed by grafting with polymeric epoxidized soybean oil (ESO) as a renewable, environmentally friendly, and low cost raw material. The grafting process occurred via ring-opening polymerization, wherein the cellulose hydroxyl groups acted as initiators in the presence of a SnCl4 catalyst, linking the cellulose fibers and ESO via ether linkages, thereby forming a polymeric matrix. The surface polarity was therefore decreased by the substitution of cellulose hydroxyl groups for long-chain hydrophobic alkane moieties from ESO. The water contact angle of modified filter paper reached 145.1° with the surface free energy decreasing to 22.07 mJ m–2 and a hydration free energy of −13.09 mJ m–2. The presence of polymeric ESO nanoparticles on the modified cellulose fibers suggested that the hydrophobicity was not only dependent on the surface composition but was also closely related to the surface morphology. To reveal the effects of surface morphology on hydrophobicity, smooth cellulose films anchored to mica plates via PVAm with a surface roughness of 1.698 nm were prepared by spin coating and modified with ESO. The thus-formed modified cellulose films also contained polymeric ESO nanoparticles which increased their roughness and enhanced their hydrophobic properties.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2015
·Vol. 132
·期 25
·
IF 1.768
Xiaoqin Chen,Bojian Hu,Xiaodong Xing,Zuliang Liu,Yan Zuo,Qian Xiang
In this article, we present a simple method for synthesizing antibacterial cellulose fibers that were modified with a cationic polymer and immobilized silver chloride (AgCl) particles. Relatively simple techniques of graft polymerization and onsite precipitation were used to fabricate the composites. Scanning electron microscopy images, Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, and energy-dispersive X-ray spectroscopy confirmed the immobilization of the AgCl particles. The observed inhibition zone of the immobilized AgCl particle composites indicated that the biocidal silver ions were released from the composites in aqueous solution. Compared with cationic-polymer-grafted cellulose fibers or AgCl alone, the cationic polymer/AgCl composites showed excellent antibacterial activity against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus . © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 42092.
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高影响因子
COLLOID AND POLYMER SCIENCE
·
2015
·Vol. 294
·期 1
·135-143
·
IF 1.865
Guo Yanzhu,Zhang Li,Li Haiming,Han Ying,Zhou Jinghui,Wang Xiaohui
A series of α-tocopherol succinate-conjugated hydroxyethyl cellulose (HEC-TOS) polymers were synthesized in this study. The weight percentages of TOS in HEC-TOS were varied from 15 to 36 % by adjusting the weight ratios of TOS to HEC from 1:4 to 5:2. The HEC-TOS polymers exhibited typical properties of amphiphilic polymers and were able to self-assemble into spherical nanomicelle in aqueous solution as revealed by TEM. The micelle sizes and critical micelle concentrations (CMC) of HEC-TOS conjugates were correlated with their molecular structures and were in the range of 24.5–115.1 nm and 16–99 μg/ml, respectively. Paclitaxel (PTX) was encapsulated into the core of HEC-TOS micelle by sonication-dialysis method. The highest loading concentration of PTX in micelle was 315 mg/ml, which was about 50 times higher than that in water (6 mg/l). The in vitro study showed that PTX was continuously released from PTX-loaded micelle in phosphate buffered saline (PBS) medium for 108 h.
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高影响因子
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