ACS Applied Materials & Interfaces
·
2016
·
IF 7.145
Tong Yang,Jun Ma,Shu Jun Zhen,Cheng Zhi Huang
Surface-enhanced Raman scattering (SERS) has shown high promise in analysis and bioanalysis, wherein noble metal nanoparticles (NMNPs) such as silver nanoparticles were employed as substrates because of their strong localized surface plasmon resonance (LSPR) properties. However, SERS-based pH sensing was restricted because of the aggregation of NMNPs in acidic medium or biosamples with high ionic strength. Herein, by using the electrostatic interaction as a driving force, AgNPs are assembled on the surface of ethylene imine polymer (PEI)/poly(vinyl alcohol) (PVA) electrospun nanofibers, which are then applied as highly sensitive and reproducible SERS substrate with an enhancement factor (EF) of 107–108. When p-aminothiophenol (p-ATP) is used as an indicator with its b2 mode, a good and wide linear response to pH ranging from 2.56 to 11.20 could be available, and the as-prepared nanocomposite fibers then could be fabricated as excellent pH sensors in complicated biological samples such as urine, considering that the pH of urine could reflect the acid–base status of a person. This work not only emerges a cost-effective, direct, and convenient approach to homogeneously decorate AgNPs on the surface of polymer nanofibers but also supplies a route for preparing other noble metal nanofibrous sensing membranes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYST
·
2016
·Vol. 141
·期 20
·5864-5869
·
IF 4.033
Ningning Zhou,Guowen Meng,Zhulin Huang,Yan Ke,Qitao Zhou,Xiaoye Hu
This report presents a simple and inexpensive fabrication approach to a flexible transparent composite film as a “cut-and-paste” surface-enhanced Raman scattering (SERS) substrate for in situ detection of organic pollutants. First, a self-assembled monolayer of Ag-nanocubes (Ag-NCs) is obtained at the air/water interface. Then, the Ag-NC monolayer is retrieved onto a flexible transparent polyethylene (PE) film to achieve an Ag-NC@PE composite film as a flexible SERS substrate. As the Ag-NCs in the monolayer are closely and uniformly packed on the PE film, the Ag-NC@PE composite film shows high SERS-activity with good signal homogeneity and reproducibility. Furthermore, the flexible transparent Ag-NC@PE composite film is “cut into” small pieces and directly “pasted” onto contaminated fruits for in situ SERS detection, as a result 10 nM thiram, 1 μM 4-polychlorinated biphenyl and 10 nM methyl parathion contaminants on oranges are detected, respectively. Therefore the Ag-NC@PE composite film is an inexpensive and effective SERS substrate for rapid in situ detection of organic pollutants in aqueous solutions, on fruits and other solid objects.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 8
·717
·
IF 4.4
Pengxing Sha,Chushu Zhu,Tianran Wang,Peitao Dong,Xuezhong Wu
In this research, a method was developed for fabricating Au–Au nanorod array substrates through the deposition of large-area Au nanostructures on an Au nanorod array using a galvanic cell reaction. The incorporation of a granular structure enhanced both the number and intensity of surface-enhanced Raman scattering (SERS) hot spots on the substrate, thereby elevating the SERS performance beyond that of substrates composed solely of an Au nanorod. Calculations using the finite difference time domain method confirmed the generation of a strong electromagnetic field around the nanoparticles. Motivated by the electromotive force, Au ions in the chloroauric acid solution were reduced to form nanostructures on the nanorod array. The size and distribution density of these granular nanostructures could be modulated by varying the reaction time and the concentration of chloroauric acid. The resulting Au–Au nanorod array substrate exhibited an active, uniform, and reproducible SERS effect. With 1,2-bis(4-pyridyl)ethylene as the probe molecule, the detection sensitivity of the Au–Au nanorod array substrate was enhanced to 10−11M, improving by five orders of magnitude over the substrate consisting only of an Au nanorod array. For a practical application, this substrate was utilized for the detection of pesticides, including thiram, thiabendazole, carbendazim, and phosmet, within the concentration range of 10−4to 5 × 10−7M. An analytical model combining a random forest and a one-dimensional convolutional neural network, referring to the important variable-one-dimensional convolutional neural network model, was developed for the precise identification of thiram. This approach demonstrated significant potential for biochemical sensing and rapid on-site identification.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2024
·
IF 6.7
Shihong Lin,Bingyan Chen,Ying Xu,Zhiyu Li,Yuanrong Liao,Jun Wang,Peiyan Yu,Yang Zhang
Synergistic surface-enhanced Raman spectroscopy (SERS) substrates, leveraging the combined strengths of electromagnetic enhancement (EM) and chemical enhancement (CM), have been extensively explored in the literature. In this study, we introduce a distinctive approach to fabricating core@shell structures, specifically employing silver nanowire @ zeolite imidazole framework-8 (AgNW@ZIF-8) as synergistic SERS substrates. Notably, these substrates offer meticulous control over shell thickness through a straightforward post-synthesis procedure. Utilizing Ag nanowires as the plasmonic core, selected for their broader localized surface plasmon resonance (LSPR) absorption range compared to nanoparticles , we encapsulate them within ZIF-8, a metal-organic framework (MOF) recognized for its proficient charge transfer (CT) properties. Our investigation encompasses the SERS performance across various Raman-active molecules, considering their diverse sizes and distinct frontier molecular orbitals (FMO) energy levels. Additionally, we systematically explore the influence of alterations in shell thickness on SERS outcomes and scrutinize the impact of probe orientation. This comprehensive study not only advances the understanding of synergistic effects intrinsic to MOFs-metal SERS substrates but also provides valuable insights for the rational design of highly sensitive substrates tailored for practical applications.
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Konghao Han,Zilong Yan,Zhuang Ding,Pengfei Zhou,Cheng Ye,Ling Qin,Zhiyong Bao,Maofeng Zhang,Wei Zhang
The proliferation of micro/nanoplastics (MNPs) has emerged as a pivotal environmental issue, largely due to their potential for human exposure. Consequently, the development of sensitive and efficient detection methodologies is paramount for elucidating their environmental footprint. Here, we report a novel three-dimensional (3D) surface-enhanced Raman scattering (SERS) sensor, which integrate Ti 3 C 2 T x /TiO 2 /W 18 O 49 semiconductor heterostructure, for the rapid and sensitive detection of MNPs in environmental matrices. The sensor's unique layered architecture and efficient charge transfer mechanism endow it with high sensitivity. It has demonstrated remarkable detection capabilities, achieving a sensitivity of 10 −8 M for Rhodamine 6G (R6G), equating to an enhancement factor (EF) of 2.33 × 10 6 . This level of sensitivity allows for the detection of polystyrene (PS) microplastics at concentration as low as 25 μg/mL, with a relative standard deviation (RSD) of 12.58 %, signifying superior reproducibility. Moreover, the sensor's fingerprinting capabilities enable the identification of a variety of MNPs, including polyethylene (PE) and polyethylene terephthalate (PET), thus facilitating the analysis of complex MNPs mixtures. The sensor's applicability to real-world samples was confirmed through the quantitative detection of PS microplastics in rainwater, soil, and industrial wastewater, with a detection limit of 25 μg/mL and exhibiting good linearity. It is concluded that the 3D SERS sensor is a promising tool for the rapid and precise detection of MNPs across diverse environmental matrices. The advent of this technology marks a significant leap forward in environmental analysis, providing a robust method for the monitoring of MNPs pollution.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Particuology
·
2024
·
IF 4.1
Hang Li,Kaisheng Yao,Tianhang Liu,Weiwei Lu,Haili Zhao
Au hierarchical architectures with special morphology and structures are strongly desired in varied applications. Herein, a simple synthesis method was developed for the one-step preparation of Au micronails (MNs) at the planar liquid-liquid interface under mild conditions. The well-defined Au MNs were grown and constructed at CHCl 3 –H 2 O interface at room temperature using aniline in CHCl 3 as reducing agent and HAuCl 4 in H 2 O as precursor and no surfactant or seed is required. The intriguing Au MNs with rough surface consist of big heads and thin rods, just like iron nails in outline. Furthermore, through simple changing the reagent concentrations, the length and surface roughness of Au MNs can be adjusted conveniently. The effects of a series of factors on the morphology and structure of the products are studied in detail. With p -aminothiophenol as a molecular probe, the as-obtained Au MNs all exhibit dramatically improved surface enhanced Raman scattering sensitivity and high reproducibility, the enhancement factor and limit of detection of Au MNs are 5.4 × 10 5 and 1.0 × 10 −10 , respectively.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Qinyi Li,Qiangting Zheng,Jiangli Shi,Yu Yan,Xiaoyu Guo,Haifeng Yang
Background Polycyclic aromatic hydrocarbons (PAHs) are one of the most dangerous persistent organic pollutants in the environment. Due to the discharge of chemical plants and domestic water, the existence of PAHs in sea water and lake water is harmful to human health. A method for rapid detection and removal of PAHs in water needs to be developed. Results In this work, we fabricate Fe 3 O 4 wrapped with gold nanoparticles decorated graphene oxide composite nanomaterial (Fe 3 O 4 /GO/Au). Excellent magnetism of Fe 3 O 4 provides a means to enrich and separate the PAHs from substrates, which effectively improve the selectivity and avoid the coffee ring effect in traditional SERS detection. Fe 3 O 4 /GO/Au shows great response to PAHs owing to the π-π electronic interaction between PAHs and GO, and through the calculation of Material Studio, it is confirmed that GO has different adsorption capacity for polycyclic aromatic hydrocarbons with different number of benzene rings. The limit of detection (LOD) of Benzo[a]pyrene (BaP) can reach 3.8 μg⋅L −1 and other PAHs can also be detected at μg⋅L −1 level. Gold nanoparticles demonstrate prominent light absorption within the visible spectrum and are characterized by their localized surface plasmon resonance (LSPR) properties. Meanwhile, Au NPs facilitate electron migration and carrier separation of GO. Owing to the synergistic interplay, the composite system Fe 3 O 4 /GO/Au exhibits the capability for SERS sensitive detection and photocatalytic degradation of BaP under visible light irradiation, realizing in-situ monitor the photodegradation of BaP in water. Significance and novelty A rapid and accurate quantitative method is established for the detection and removal of PAHs in water, which is intended to provide new strategy for the quantitative analysis and removal of water environmental pollution.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2024
·
IF 4.1
Keyan Liu,Wei Feng,Yanru Li,Donglai Han,Tianna Wu,Kaiyue Li,Shuo Yang
Surface-enhanced Raman spectroscopy (SERS) with enormous advantages has emerged as a powerful tool for both highly sensitive structural detection of analytes and various imaging applications. A notable advancement in the realm of multifunctional SERS substrates is the integration of magnetic nanoparticles endowed with magnetic manipulation capabilities and noble metal nanoparticles exhibiting plasmonic resonance properties. This synergistic combination offers substantial practical benefits for trace analysis across diverse fields. In this paper, a new paradigm of Fe 3 O 4 @PEI-DTC-Ag (Fe 3 O 4 @PD-Ag) photomagnetic nanocomposites based on magnetic Fe 3 O 4 nanoparticles (NPs), the noble metal silver quantum dots (Ag QDs) and the adhesive layer polyethyleneimine dithiocarbamate (PEI-DTC) for convenient recycling and ultrasensitive SERS detection was developed by engineering hydrothermal and seed-growth methods. The SERS performance of the Fe 3 O 4 @PD-Ag substrates with varying amounts of Ag was evaluated by detecting 4-aminothiophenol (4-ATP). Among the tested samples, Fe 3 O 4 @PD-Ag-4 with a silver solution volume of 200 ml exhibited the optimal performance, showcasing an enhancement factor ( EF ) of 4.418 × 10 5 . Moreover, the relative standard deviations (RSDs) were calculated to be less than 11.5 %, demonstrating the SERS substrates exhibit good uniformity and spectral reproducibility. Of note, the SERS substrate has demonstrated successful trace detection of thiram molecules, achieving a limit of detection (LOD) of up to 10 -9 M. The intensity of SERS signals shows a linear correlation with the logarithm of thiram concentration, ranging from 10 -4 to 10 -9 M, thus providing compelling evidence for quantitative detection. Importantly, the Fe 3 O 4 @PD-Ag-4 SERS substrate also showcases outstanding performance for detecting thiram in real food, underscoring its significant potential for application in food safety monitoring.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yansheng Liu,Yongquan Wei,Guofu Wang,Xiaobo Jia,Jin Zhou,Hongqi Li,Haixin Chang,Zhaoxu Li
Surface-enhanced Raman scattering (SERS) spectroscopy plays an important role in enabling high-precision detection and non-invasive diagnostics. Periodic metallic nanostructures with strong electromagnetic fields and tunable localized surface plasmon resonance can achieve high SERS sensitivity, but fabricating such nanostructures remains a challenge. In this work, the anodic aluminum oxide (AAO) nanocavity template-assisted process of fabricating periodic nanostructures with modulating morphologies from Ag nanoclaws (AgNCWs) to Ag nanocones (AgNCEs) is proposed. The morphologies-related SERS performances of nanostructures are analyzed by using rhodamine 6 g (R6G) as a probe molecule and the optimized AgNCEs possess a limit of detection (LOD) of 1 × 10 −9 M. A sandwich strategy is applied to detect SARS-CoV-2 S protein in phosphate-buffered saline (PBS) and pharyngeal swab solution (PSS). The ACE2-modified AgNCEs (ACE2/AgNCEs) structure is applied to bind to the SARS-CoV-2 S protein. The 4-MBA and SARS-CoV-2 S antibody functionalized Au nanoparticles (AuNPs) are used as nanotags. By forming the ACE2/AgNCEs-SARS-CoV-2 S protein-nanotags sandwich structure, characteristic peak intensities of 1580 cm −1 are used as the report signal, and the LOD for SARS-CoV-2 S protein in PBS and PSS solution are 10 fg/mL.
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Kexin Ren,Mengxia Duan,Tingting Su,Dichen Ying,Shijia Wu,Zhouping Wang,Nuo Duan
Shiga toxin type II (Stx2), the major virulence component of enterohemorrhagic Escherichia coli , is strongly associated with the life-threatening hemolytic uremic syndrome thus posing a substantial risk to food safety and human health. In this work, a dual-mode aptasensor with colorimetric and surface-enhanced Raman scattering was developed for Stx2 specific detection based on noble metal nanoparticles and Raman reporter loaded metal-organic framework (Mn/Fe-MIL(53)@AuNSs-MBA). The Mn/Fe-MIL(53)@AuNSs could catalyze the H 2 O 2 -mediated oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB), thereby enabling visual detection. Meanwhile, the SERS signal from MBA can be enhanced by the decorated AuNSs. Under optimal conditions, a linear range of 0.05–500 ng/mL with limit of detection (LOD) of 26 pg/mL was achieved in colorimetric mode and a linear range of 5–1000 ng/mL with LOD of 0.82 ng/mL in SERS mode, in which the dual-mode results complement each other, widening the linear range, increasing the accuracy and reliability of the detection. The method was further applied to the detection of Stx2 in milk with average recovery of 101.1 %, demonstrating its superior potential for bacterial toxin monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sensors
·
2024
·
IF 8.2
Linge Nian,Wenhua Li,Chunxia Zhang,Lu Li,Guangrui Zhang,Jianxi Xiao
Hepatic fibrosis, the insidious progression of chronic liver scarring leading to life-threatening cirrhosis and hepatocellular carcinoma, necessitates the urgent development of noninvasive and precise diagnostic methodologies. Denatured collagen emerges as a critical biomarker in the pathogenesis of hepatic fibrosis. Herein, we have for the first time developed 3D-printed collagen capture chips for highly specific surface-enhanced Raman scattering (SERS) detection of denatured type I and type IV collagen in blood, facilitating the early diagnosis of hepatic fibrosis. Employing a novel blend of denatured collagen-targeting peptide-modified silver nanoparticle probes (Ag@DCTP) and polyethylene glycol diacrylate (PEGDA), we engineered a robust ink for the 3D fabrication of these collagen capture chips. The chips are further equipped with specialized SERS peptide probes, Ag@ICTP@R1 (S–I) and Ag@IVCTP@R2 (S–IV), tailored for the targeted detection of type I and IV collagen, respectively. The SERS chip platform demonstrated exceptional specificity and sensitivity in capturing and detecting denatured type I and IV collagen, achieving detection limits of 3.5 ng/mL for type I and 3.2 ng/mL for type IV collagen within a 10–400 ng/mL range. When tested on serum samples from hepatic fibrosis mouse models across a spectrum of fibrosis stages (S0–S4), the chips consistently measured denatured type I collagen and detected a progressive increase in type IV collagen concentration, which correlated with the severity of fibrosis. This novel strategy establishes a benchmark for the multiplexed detection of collagen biomarkers, enhancing our capacity to assess the stages of hepatic fibrosis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 3
·1-13
·
IF 5.3
Wang Yutong,Liu Yizhi,Liang Xiao,Liu Zhiyuan,Yang Yaling
This study successfully developed a colorimetric/SERS dual-mode sensor for determining acrylamide in baked goods based on the excellent peroxidase-like activity and Raman activity of Fe-PHS@Au–Ag-Au Janus NPs. In colorimetric mode, the thiol-ene Michael addition between acrylamide (AA) and glutathione (GSH) efficiently eliminates GSH-induced peroxidase-like activity inhibition. The peroxidase-like activity of Fe-PHS@Au–Ag-Au Janus NPs gradually recovered, and the blue color of the solution gradually deepened with the increase in AA dosage. In surface-enhanced Raman spectroscopy (SERS), Apt-Fe-PHS@Au–Ag-Au Janus NPs can selectively capture AA and bind specifically, leading to the dissociation of Apt and Fe-PHS@Au–Ag-Au Janus NPs. The Raman activity of Apt-Fe-PHS@Au–Ag-Au Janus NPs decreases due to the dissociation of Apt. The dual-mode sensor was utilized for the determination of acrylamide in the concentrations range from 0.05 to 20 µg·L −1 with detection limits of 0.06 µg·L −1 (SERS) and 0.01 µg·L −1 (colorimetric). The recovery in baked samples was between 91.0 and 108.0%. Graphical
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）