Nanoscale
·
2013
·Vol. 5
·期 17
·8056-8066
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IF 6.233
Song Shen,Fenfen Kong,Xiaomeng Guo,Lin Wu,Haijun Shen,Meng Xie,Xinshi Wang,Yi Jin,Yanru Ge
With the potential uses of photothermal therapy (PTT) in cancer treatment with excellent efficacy, and the growing concerns about the nanotoxicity of hyperthermia agents such as carbon nanotubes and gold-based nanomaterials, the importance of searching for a biocompatible hyperthermia agent cannot be emphasized too much. In this work, a novel promising hyperthermia agent employing magnetic Fe3O4 particles with fairly low toxicity was proposed. This hyperthermia agent showed rapid heat generation under NIR irradiation. After modification with carboxymethyl chitosan (CMCTS), the obtained Fe3O4@CMCTS particles could disperse stably in PBS and serum without any aggregation. The modification of CMCTS could decrease the adsorption of bovine serum albumin (BSA) and improve the cellular uptake. In a comparative study with hollow gold nanospheres (HAuNS), Fe3O4@CMCTS particles exhibited a comparable photothermal effect and fairly low cytotoxicity. The in vivo magnetic resonance (MR) images of mice revealed that by attaching a magnet to the tumor, Fe3O4@CMCTS particles accumulated in the tumor after intravenous injection and showed a low distribution in the liver. After being exposed to a 808 nm laser for 5 min at a low power density of 1.5 W cm−2, the tumors on Fe3O4@CMCTS-injected mice reached a temperature of ∼52 °C and were completely destroyed. Thus, a kind of multifunctional magnetic nanoparticle with extremely low toxicity and a simple structure for simultaneous MR imaging, targeted drug delivery and photothermal therapy can be easily fabricated.
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CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Gang Li,Ruiyang Tan,Bohong Gao,Xinli Liu,Mingyuan Zhang,Ping Chen,Xinyi Wang
Developing advanced electromagnetic wave absorption (EMWA) materials is crucial for curbing electromagnetic pollution. This study presents the synthesis of core–shell Fe/Fe 3 O 4 /C composites, FFC-700 and FFC-800, derived from Prussian blue@covalent organic framework (PB@COF) via pyrolysis at 700 and 800 °C, and the hollow FFC-900 at 900 °C. Their chemical compositions, microstructures, and EMWA performances were thoroughly examined. FFC-700 and FFC-800, featuring core–shell structures and abundant interfaces, facilitate electron transfer and enhance polarization effects. Notably, FFC-700 achieved a minimum reflection loss (RL min ) of − 75.82 dB at an ultrathin thickness of 1.45 mm, with an effective absorption bandwidth (EAB) of 6.22 GHz at 1.66 mm, spanning the entire Ku-band. FFC-800 also provides substantial EMWA performance, with an RL min of − 30.14 dB at 1.61 mm and an EAB of 6.08 GHz at 1.67 mm, also covering the Ku-band. Radar cross-section (RCS) simulations reveal the absorbers’ exceptional radar stealth, with their coatings significantly reducing RCS values. The composites’ adjustable structure, balanced composition, and dielectric-magnetic synergy optimize impedance matching for full-Ku-band coverage. This work offers a promising approach to fabricating efficient EMWA materials from PBA@COF and MOF@COF precursors.
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CHEMOSPHERE
·
2024
·
IF 8.1
Cunkuan Zhang,Xiaolan Zeng,Xiaotang Xu,Wenbo Nie,Brajesh Kumar Dubey,Wenchuan Ding
Anode modification is an effective strategy for enhancing the electrochemical performance of microbial fuel cell (MFC). However, the impacts of the modified materials on anode biofilm development during MFC operation have been less studied. We prepared a novel PDA-Fe 3 O 4 -CF composite anode by coating original carbon felt anode (CF) with polydopamine (PDA) and Fe 3 O 4 nanoparticles. The composite anode material was characterized by excellent hydrophilicity and electrical conductivity, and the anodic biofilm exhibited fast start-up, higher biomass, and more uniform biofilm layer after MFC operation. The MFC reactor assembled with the composite anode achieved a maximum power density of 608 mW m −2 and an output voltage of 586 mV, which were 316.4% and 72.4% higher than the MFC with the original CF anode, respectively. Microbial community analysis indicated that the modified anode biofilm had a higher relative abundance of exoelectrogen species in comparison to the unmodified anode. The PICRUSt data revealed that the anodic materials may affect the bioelectrochemical performance of the biofilm by influencing the expression levels of key enzyme genes involved in biofilm extracellular polymer (EPS) secretion and extracellular electron transfer (EET). The growth of the anodic biofilm would exert positive or negative influences on the efficiency of electricity production and electron transfer of the MFCs at different operating stages. This work expands the knowledge of the role that anodic materials play in the development and electrochemical performance of anodic biofilm in MFCs.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Chengmin Hou,Weimin Yan,Hanxiao Ma,Yuan Bai,Zhiting Yuan
Heavy metal ion (Cu(II)) wastewater will do great harm to human body and environment, and the adsorption materials used in traditional adsorption methods are easy to hydrolyze, resulting in secondary pollution to water. In this paper, an adsorption material poly(glycidyl methacrylate-random-hydroxyethyl methacrylate) grafted ferric oxide@starch (St/Fe 3 O 4 - g -p(GMA- r -HEMA)) was prepared, which had epoxy and hydroxyl group , easy to produce crosslinking, reduce the sensitivity of starch to pH and prevent hydrolysis. Infrared spectroscopy (FTIR), thermogravimetric analysis (TG), scanning electron microscopy (SEM) and magnetometer (VSM) were used to characterize the structure and morphology of the adsorbent. The adsorption properties of the adsorbent for removal of Cu(II) ions were studied via changing the experimental conditions, including the amount of adsorbent, Cu(II) ions solution concentration, pH value, adsorption time, adsorption temperature and so on. Under the optimal adsorption conditions of pH value 7, initial Cu(II) concentration 20 mg/L and adsorption time 160 min, the maximum unit adsorption capacity of St/Fe 3 O 4 - g -p(GMA- r -HEMA) was 94.15 mg/g, and the adsorption performance was good. The adsorption process followed Langmuirm model and second-order kinetic model , and was dominated by chemisorption . The thermodynamic model showed that the adsorption process of St/Fe 3 O 4 - g -p(GMA- r -HEMA) was endothermic. After 8 adsorption cycles, 93.5% of the first adsorption effect can still be retained, and the renewable performance had been improved.
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Food and Bioprocess Technology
·
2024
·
IF 5.3
Shi Yingkun,Niu Zijun,Chen Sichun,Wang Songlei,Yang Lingfan,Wang Yihua
Abstract Electrochemical analysis is a powerful analytical technique with extensive applications in the food industry, offers high advantages due to its high sensitivity, low operating cost, and high-speed analysis. In this study, a novel nanoenzymes high-catalytic platform based on a conductive polymer (MXene) was established for the detection of Guanosine 5′-monophosphate (GMP). The MXene/Fe 3 O 4 /β-CD nanocomposites were synthesized using a self-assembly method, exhibiting significant catalytic activity and a large specific surface area. The surface morphology, functional groups and chemical bonds of MXene/Fe 3 O 4 /β-CD were analyzed via scanning electron microscopy (SEM), Fourier Transform Infrared (FT-IR) and X-ray photoelectron spectroscopy (XPS). Electrochemical experiments indicated a significant amplification of GMP electrical signals on the nanoenzymatic platform. The oxidation of GMP to 8-oxo-GMP involved the transfer of two electrons (−2e − ) and two protons (-2H + ) at the MXene/Fe 3 O 4 /β-CD modified glassy carbon electrode. Under optimized conditions, this electrochemical nanoenzymatic platform achieved a low detection limit of 0.0126 μM for GMP, with linear ranges from 0.05 μM to 600 μM. The sensor demonstrated excellent selectivity and stability and was successfully applied for GMP determination in chicken, fish, pork and beef samples. This study provided a new pathway for the development of sensors for GMP detection. Graphical Abstract
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2024
·
IF 4.1
Qian Zhang,Xiaoqin Sun,Yuan Dang,Jun-Jie Zhu,Yuanzhen Zhou
In this work, Fe 3 O 4 -anchored nitrogen-doped carbon catalyst (Fe 3 O 4 @N–C) with abundant oxygen vacancies (V o ) and mesoporous structure was successfully synthesized for electro-Fenton (EF) catalytic process. The catalyst demonstrated impressive degradation efficiency towards nitroso-containing organics due to the superior electronic transfer of N–C skeleton and V o , making it easier for the electron-deficient –NO 2 groups to adsorb on the catalyst surface and oxidize rapidly. Typically, the degradation efficiency of p-nitrophenol (PNP) reached 95.6 % in natural pH. Notably, the catalyst exhibited excellent performance over a wide pH range (3 ∼ 11), and has strong anti-interference performance against anions and natural organic matter in water matrix. Mechanism analysis indicated that V o could promote the formation of highly active electron-rich Fe(II) species, and promote the activation of H 2 O 2 and O 2 as additional active sites, thus, a large amount of ·OH and O 2 ·- would be produced and then quickly converted into 1 O 2 . As a result, 1 O 2 is the main reactive species for PNP degradation in Fe 3 O 4 @N–C electro-Fenton reaction. The results will provide insights into the design of high-performance catalysts for the selective oxidation of organic pollutants in wastewater.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 2
·1-13
·
IF 5.3
Zhang Jiadong,Cui Yaoying,Dou Yanchao,Zhu Jingying,Ma Xiangyu,Guo Liming,Zhang Kai,Hao Nan,Feng Liangdong,Chen Yi
A highly sensitive and selective electrochemical biosensor was developed for the detection of kanamycin using a core-hollow-shell structured peroxidase-mimic nanozyme, CHS-Fe₃O₄@@ZIF-8. The synthesized CHS-Fe 3 O 4 @@ZIF-8 was characterized with scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy. It was found that the CHS-Fe 3 O 4 @@ZIF-8 exhibits excellent peroxidase-like activity due to its ultra-thin hollow layer. Besides, CHS-Fe 3 O 4 @@ZIF-8 functionalized with complementary chains of kanamycin aptamer was anchored to the electrode surface via complementary base pairing with the kanamycin aptamer. Upon the presence of kanamycin, a strand displacement reaction was triggered leading to a reduction in the number of the CHS-Fe 3 O 4 @@ZIF-8, which slowed down the catalytic reaction of the substrate 3,3’,5,5’ -tetramethylbenzidine (TMB) facilitated by CHS-Fe 3 O 4 @@ZIF 8. Differential pulse voltammetry (DPV) was employed to measure and record changes in peak current resulting from catalytic oxidation product formation (oxidation product of TMB). The electrochemical signal exhibited a linear relationship with logarithmic variations in kanamycin concentration within a range spanning from 10 to 8000 pM and achieved an impressive detection limit as low as 7.52 pM. Furthermore, successful detection of kanamycin content in serum samples using this sensor demonstrated its good specificity and reproducibility. These findings indicate that the constructed electrochemical kanamycin sensor holds significant potential for practical applications. The biosensor demonstrated high selectivity, distinguishing kanamycin from other antibiotics, and exhibited good reproducibility, making it reliable for practical applications. The successful detection of kanamycin in serum samples further underscores the sensor’s potential for real-world applications, particularly in monitoring antibiotic residues in food products and clinical diagnostics. Graphical
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yigui Tang,Zongsu Wei,Chi Wang,Ping Ning,Minghui He,Shuangyou Bao,Xin Sun,Kai Li
Landfill disposal of manganese slag is a significant environmental concern on both local and global levels. Using manganese slag to synthesis catalysts to degrade organic pollutants in wastewater is a promising pathway for the solid waste treatment. Here, we propose a simple method to prepare magnetic catalysts containing Mn 3 O 4 -Fe 3 O 4 (MMF) using manganese slag as raw materials. The MMF exhibits excellent degradation performance for enrofloxacin (ENR) with 97 % removal efficiency within 30 min and can be rapidly isolated from wastewater by magnet. Electron paramagnetic resonance (EPR) and quenching experiments demonstrated that 1 O 2 produced by the non-radical pathway is the principal active substance for ENR degradation. X-ray photoelectron spectroscopy (XPS) and density-functional theory (DFT) calculations indicate that Mn and Fe in MMF provide electrons for PMS activation and that the presence of Fe promotes the activation of the PMS and the cycling of Mn. This work paves the way for developing magnetic catalysts from manganese slag for the treatment of organic pollutants via advanced oxidation process.
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Nanomaterials
·
2025
·Vol. 15
·期 5
·341
·
IF 4.3
Yaohui Xu,Yuting Li,Quanhui Hou,Liangjuan Gao,Zhao Ding
Based on the magnetic sensitivity of Fe3O4in various fields, we aimed to propose a one-step solvothermal process for the synthesis of single-phase Fe3O4induced by the reaction medium and urea, avoiding high-temperature reduction in H2or N2atmospheres. Feasibility was tested with purified water (H2O), methyl alcohol (MA), ethyl alcohol (EA), and ethylene glycol (EG) as reaction media. The findings indicated that the solvothermal reaction system utilizing EA was more effective for the synthesis of cubic magnetic Fe3O4. Optimal conditions for synthesizing pure Fe3O4were obtained by optimizing the urea amount and solvothermal reaction parameters. The optimal formulation consisted of 10 mmol of FeCl3, 80 mmol of urea, and 60 mL of EA subjected to a solvothermal process at 200 °C for 12 h. The resulting Fe3O4(magnetite, cubic) exhibited commendable crystallization with a morphology of acicular aggregates and displayed excellent magnetic sensitivity properties with a magnetization of 92.2 emu/g at 15,000 Oe. The photocatalytic degradation behaviors of the resulting Fe3O4to Methyl Orange, Orange G, and Acid Red 37 azo dyes and the repeated degradation performance of Methyl Orange dye were investigated. Nearly complete degradation of Methyl Orange dye occurred after 2.0 h of photocatalytic reaction, while Orange G and Acid Red 37 dyes achieved similar results after 3.5 and 4.5 h, respectively. The exploration strategy in this work for synthesizing magnetic Fe3O4can be applied to design and fabricate other metal oxides or composites, potentially resulting in novel discoveries in morphology or performance.
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JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Xiao Dai,Xianhong Zhu,Shiyu Li,Ze Wu,Chenyang Zhao,Xun Gao,Longshan Zhao
Some illegal businesses often add antibiotics such as sulfonamides to expand the functional range of lipstick. However, the abuse of antibiotics will lead to serious adverse reactions and increase the drug resistance of bacteria. To ensure the safety of lipstick, it is necessary to monitor the antibiotic content, which urgently needs to develop an efficient and highly sensitive analytical method. In this study, a magnetic solid-phase extraction (MSPE) method was developed using a composite adsorbent based on carboxylated multi-walled carbon nanotubes (c-MMWCNT) and carbon dots (CDs) for sample pretreatment. A magnetic dispersive solid-phase extraction coupled with high-performance liquid chromatography method was established using silanized serine‑modified carbon dots (Sil-Ser-OCDs) as the sorbent for the determination of sulfapyridine (SPY) and sulfamethazine (SMT). Key extraction parameters including adsorbent dosage, extraction time, and pH were optimized using response surface methodology. The optimal extraction conditions were determined to be an adsorbent dosage of 72 mg, extraction time of 4.5 min, and pH 6.0. Under the optimal conditions, the recoveries of SPY and SMT were in the range of 88.0%-93.4%, and the RSD values of intra-day and inter-day precision were under 4.2% and 5.4%, respectively, indicating that the approach has excellent accuracy and precision.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Erqiao Chen,Zhihao Chen,Zhongting Liu,Mingzhu Zhou,Bisheng Li,Renjie Li,Liguo Shen,Yang Jiao,Hongjun Lin,Yanchao Xu
Membrane fouling and the inherent permeability–selectivity trade-off represent persistent dual challenges constraining the long-term performance and practical application of nanofiltration (NF) membranes. Saline wastewater and dye-containing effluents are typical industrial wastewaters with large discharge volumes, where high salt contents and complex organic components exacerbate fouling and intensify the permeability–selectivity dilemma of conventional NF membranes. In this work, we report a novel magnetic-field-assisted interfacial polymerization strategy to fabricate photocatalytic thin-film nanocomposite (M-TFN) membranes with enhanced antifouling and self-cleaning performance. A multifunctional nanostructure, Fe 3 O 4 @CdS@CQDs, was synthesized via a one-pot hydrothermal method and introduced into the aqueous phase of interfacial polymerization. Under an external magnetic field, the nanoparticles were guided toward the water–organic interface, inducing the formation of a wrinkled polyamide surface with increased roughness, hydrophilicity, and specific surface area. Compared with the conventional TFC (6.1 L·m −2 ·h −1 ·bar −1 , 98.2 % Na 2 SO 4 rejection) and TFN membranes (15.7 m −2 ·h −1 ·bar −1 , 99.0 % Na 2 SO 4 rejection), the resulting M-TFN membranes exhibited a significantly improved water flux of 22.5 m −2 ·h −1 ·bar −1 while maintaining a high Na 2 SO 4 rejection of 99.2 %, thereby effectively overcoming the permeability–selectivity trade-off. Moreover, the membranes demonstrated excellent dye rejection (>95 % for multiple organic dyes) and outstanding photocatalytic self-cleaning behavior under visible light, achieving a flux recovery rate of 98.7 % after five fouling–cleaning cycles. This study provides new insights into the synergistic use of magnetic guidance and photocatalytic enhancement to design next-generation NF membranes for advanced wastewater treatment.
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Computational and Structural Biotechnology Journal
·
2025
·
IF 4.1
Tianzhu Guan,Chenxi Ren,Yining Feng,Canfeng Bian,Huaxiang Li,Qingling Wang
As one of the endocrine-disrupting compounds (EDCs), diethylstilbestrol (DES) poses significant risks to ecosystems and human health. This study reports the development of a magnetic nanocomposite (Fe₃O₄@Al³⁺@laccase) via glutaraldehyde (GA) crosslinking to enhance DES degradation. The single factor experiments revealed that the optimum immobilization conditions were: temperature 40℃, pH 5, enzyme concentration 1.0 mg/mL, and immobilization time 1.0 h. Under these conditions, Fe₃O₄@Al³⁺@laccase achieved 91.71%±2.95% DES degradation within 12 h, as validated by HPLC, retaining 31.29%±1.99% of its initial catalytic activity after 10 reuse cycles. Notably, the immobilized laccase exhibited superior stability in organic solvents compared to free laccase. Fourier-transform infrared (FTIR) analysis confirmed that laccase was successfully conjugated onto Fe₃O₄@Al³⁺. Scanning electron microscopy and transmission electron microscopy revealed that the immobilization process preserved the original morphology and crystalline structure of Fe₃O₄@Al³⁺. Multi-spectroscopic analyses, including enzyme kinetics, fluorescence, and three-dimensional (3D) spectroscopy, elucidated the binding affinity and conformational changes between laccase and DES. Molecular docking simulations predicted a binding free energy of −6.4 kJ·mol⁻¹, indicating that the conformation stability between laccase and surrounding free amino acids was mainly maintained via van der Waals, pi-pi T-shaped, Pi-Donor Hydrogen Bond, and Pi-Alkyl. This work provides proof-of-concept for using Fe₃O₄@Al³⁺ as a reusable magnetic support for laccase, offering a promising strategy for DES degradation and guiding the design of advanced nanomaterials for environmental bioremediation.
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