JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 33
·15797-15812
·
IF 3.553
Weng Mingmei,Zhu Qi,Wang Aiwen,Liu Guanjin,Huang Honghao
Abstract A SnO 2 @β-Fe(Zr)OOH nanocomposite, β-FeOOH doped with Zr on SnO 2 hollow spheres, was synthesized by two-step hydrothermal method to solve the problem of nitrate pollution in sewage. The structure and properties of samples which synthesized in this work were analyzed by means of XRD, SEM, TEM, XPS, BET and Zeta potential systematically. Moreover, the effects of initial nitrate concentration, pH, time and temperature on nitrate removal were also investigated. The amount of nitrate nitrogen adsorbed by the SnO 2 @β-Fe(Zr)OOH nanocomposite was 14.0 mg/g in the first 30 min. Based on the analysis of the nitrate adsorption kinetic model of SnO 2 @β-Fe(Zr)OOH nanocomposite in water, the adsorption was in line with the second-order kinetic model and belonged to chemical adsorption. It showed that the Langmuir adsorption isotherm model fitting results are superior to the Freundlich isothermal adsorption model through fitting the adsorption isotherm. With the increase of temperature, the maximum adsorption capacity showed the same trend, which indicated that the adsorption process is an endothermic process. In addition, adsorption thermodynamic studies were carried out to prove that the reaction process is a spontaneous reaction. After six adsorption–desorption cycles, the composite still has an adsorption capacity of 80%. Graphic abstract
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-10
·
IF 6.232
Guo Liying,Wu Jingyu,Xing Fei,Liu Weihua,Hao Lin,Wang Chun,Wu Qiuhua,Wang Zhi
Graphene-carbon nanosphere composite (G@CNS) was prepared via a simple hydrothermal method. The G@CNS nanocomposite was characterized by X-ray diffraction, scanning electron microscope, surface area, and porosity analysis. The G@CNS was applied as a new sorbent for solid-phase extraction of five carbamate pesticides (tsumacide, carbaryl, isoprocarb, bassa, diethofencarb) prior to quantitative determination by high-performance liquid chromatography with ultraviolet detection at 208 nm. Some experimental parameters including desorption conditions, sample pH, sample volume, and loading rate were studied carefully. Under the optimized condition, the method provided good linearity ranging from 0.3 to 100.0 ng mL −1 with low limits of detection of 0.10–0.20 ng mL −1 for grape juice, 0.10–0.30 ng mL −1 for blend fruit juice, and 0.10–0.20 ng mL −1 for water sample. Good method recoveries (80.2–110%) with relative standard deviations less than 7.2% and high enrichment factors (167–293) were achieved. Results demonstrated that this novel G@CNS can serve as a promising alternative sorbent for more applications.
In this work, a graphene-carbon nanosphere (G@CNS) composite was synthesized via a simple hydrothermal method. Then, the G@CNS was served as a novel sorbent for solid-phase extraction of five carbamate pesticides (tsumacide, carbaryl, isoprocarb, bassa, diethofencarb) in juice and environmental water samples, followed by their quantitative analysis with high-performance liquid chromatography-ultraviolet detection.
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IONICS
·
2020
·Vol. 26
·期 12
·6035-6047
·
IF 2.394
Yan Yinglin,Fan Chaojiang,Yang Yanyun,Xie Yigui,Cao Ye,Lin Jiaming,Zou Yiming,You Caiyin,Xu Yunhua,Yang Rong
In this study, three types of biomass with different structures were selected to synthesize carbon matrix in a cathode of Li-S battery. The influence of the structure of raw biomass on microstructure, sulfur-loading amount, and electrochemical performance was investigated in detail. The results demonstrated that the catkin-derived porous carbon (CPC) inherited the 1D-structured morphology and exhibited the highest specific surface area (2033.09 m 2 /g), the largest sulfur loading (53.72%), and the highest initial discharge specific capacity (1369.52 mA h g −1 ) under 0.1 C. Comparatively speaking, the wrinkled cloth-like sakura petal–derived porous carbon showed a better capacity (1218.14 mA h g −1 ) but poor cycling performance. And the 3D network structure of bamboo-derived porous carbon (BPC) exhibited a relatively high capacity retention. These results demonstrated that the structural feature of biomass raw materials plays an important role in the microstructure and electrochemical performance of the carbon products.
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BMC MICROBIOLOGY
·
2021
·Vol. 21
·期 1
·1-10
·
IF 3.605
Xu Meng,Lu Feifeng,Lyu Chenang,Wu Qingping,Zhang Jumei,Tian Peng,Xue Liang,Xu Ting,Wang Dapeng
Background Human noroviruses (HuNoVs) are a major cause of nonbacterial gastroenteritis in all age groups worldwide. HuNoVs can be detected in vitro using molecular assays such as RT-PCR and RT-qPCR. However, these molecular-based techniques require special equipment, unique reagents, experienced personnel, and extended time to obtain results. Besides, the diversity of viral genotypes is high. Therefore, methods that are rapid, broad-range and effective in the detection of HuNoVs are desiderated for screening the feces or vomit of infected people during outbreaks. Results In this study, a colloidal-gold-based immunochromatographic assay (ICA) was developed for effective detection of HuNoVs in clinical samples. Monoclonal antibodies (MAbs) against the shell (S) domain in the major capsid protein of HuNoVs were used in the ICA. The limitations of detection for HuNoVs in clinical samples were 1.2 × 10 6 genomic copies per gram of stool sample (gc/g) and 4.4 × 10 5 gc/g for genogroup I and II (GI and GII) HuNoVs, respectively. A total of 122 clinical samples were tested for HuNoVs by ICA and compared against RT-qPCR. The relative sensitivity, specificity and agreement of ICA was 84.2% (95% CI: 83.6–84.8%), 100.0% (95% CI: 98.5–100.0%) and 87.7% (95% CI: 85.6–89.8%), respectively. No cross-reaction with other common enteric viruses or bacteria was observed. The ICA detected a broad range of genotypes, including GI.1, GI.3, GI.4, GI.6, GI.14, GII.2, GII.3, GII.4, GII.6, GII.13, and GII.17 HuNoVs. Conclusions This study demonstrates that ICA targeting the S domain of VP1 is a promising candidate for effectively identifying the different genotypes of HuNoVs in clinical samples with high sensitivity and specificity.
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CATALYSIS LETTERS
·
2021
·Vol. 151
·期 9
·2560-2569
·
IF 3.186
Han Jishu,Wang Ying,Liu Ying,Bai Jiayu,Zhao Ruiyang,Wang Lei
In this paper, novel CdSe/NH 2 -MIL-101(Cr) nanocomposites for photocatalytic hydrogen production were synthesized. When the prepared NH 2 -MIL-101(Cr) MOFs were modified with CdSe QDs, the photocatalytic hydrogen production amount was significantly increased and reached to 17,664 μmol g −1 in 7 h. The formation of CdSe/NH 2 -MIL-101(Cr) nanocomposites enhanced the light absorption intensity, broadened the visible light absorption range, promoted the transfer of photogenerated electrons and inhibited the recombination of photogenerated electron–hole pairs, then effectively improved the photocatalytic hydrogen production performance. In addition, the CdSe/NH 2 -MIL-101(Cr) nanocomposites exhibited high cycle stability, which was beneficial to the practical application in photocatalytic hydrogen production. Graphic Abstract
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BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
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2020
·Vol. 105
·期 6
·841-846
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IF 1.657
Wang Zhuang,Song Lan,Zhang Fan,Wang De-Gao
We experimentally investigated the toxicity of stannic oxide nanoparticles (SnO 2 NPs) to three freshwater species including Scenedesmus obliquus , Daphnia magna , and Danio rerio . To evaluate effect, toxicological impacts were compared to that of stannic chloride (SnCl 4 ). Based on the actual concentration of Sn, SnO 2 NPs suspensions inhibited growth of S. obliquus in a dose-dependent manner, demonstrating a median effect concentration of 2.28 ± 0.53 mg/L. However, SnO 2 NP suspensions were found to exhibit limited acute toxicity in D. magna and D. rerio . Moreover, the toxicity of the SnO 2 NP suspension was lower than SnCl 4 for all three trophic aquatic organisms. Comparison of component-specific contribution to overall toxicity indicated that, in SnO 2 NP suspensions, particulate Sn more significantly contributed to toxicity than dissolved Sn-ions. Furthermore, we found that the toxic mechanism of the SnO 2 NP suspension involved the induction of oxidative stress by increasing intracellular ROS accumulation.
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CHINESE JOURNAL OF POLYMER SCIENCE
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2020
·Vol. 39
·期 5
·537-544
·
IF 3.154
Lv Xiao-Jing,Xu Li-Bin,Qian Liang,Yang Yuan-Yuan,Xu Zhi-Yi,Li Jin,Zhang Cheng
An imidazolium-based ionic liquid (IL) modified triphenylamine derivative, namely 1-(4-((4-(diphenylamino)benzoyl) oxy)butyl)-3-methyl imidazole tetrafluoroborate (TPAC 6 IL-BF 4 ), was designed and synthesized, and further applied with 3,4-ethylene dioxythiophene (EDOT) to prepare conjugated copolymer P(EDOT:TPAC 6 IL-BF 4 ) via electrochemical polymerization. The cyclic voltammetry curves show that the copolymer P(EDOT:TPAC 6 IL-BF 4 ) possesses two pairs of redox peaks, which should be ascribed to the redox behaviors of EDOT and triphenylamine. The ultraviolet-visible (UV-Vis) absorption spectrum of P(EDOT:TPAC 6 IL-BF 4 ) exhibits one maximum absorption peak at 580 nm and a small shoulder characteristic peak at 385 nm under neutral state which are assigned to π-π * conjugated structure of EDOT and triphenylamine. After being applied at the positive voltage, the copolymer color changes from dark blue to light blue, which is close to the color of poly(3,4-ethylenedioxythiophene) (PEDOT). Surprisingly, the copolymer P(EDOT:TPAC 6 IL-BF 4 ) shows shorter switching time of 0.37 s, 0.30 s at 580 nm and 0.38 s, 0.45 s at 1100 nm compared with PEDOT. It is more intriguing that the copolymer P(EDOT:TPAC 6 IL-BF 4 ) exhibits electrochromism even in free supporting electrolyte. The results confirm that the existence of imidazolium-based ionic liquid has an improvement on the ion diffusion properties and the switching time of conjugated polymer, which may provide a potential direction for the preparation of high-performance electrochromic materials.
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Journal of Natural Medicines
·
2020
·Vol. 75
·期 1
·129-141
·
IF 2.055
An Meng-Fei,Wang Ming-Yue,Shen Chang,Sun Ze-Rui,Zhao Yun-Li,Wang Xuan-Jun,Sheng Jun
Abstract Isoorientin (ISO), a natural flavonoid compound, has been identified in several plants and its biological activity is determined and the study on lowering uric acid has not been reported. In view of the current status of treatment of hyperuricemia, we evaluated the hypouricemic effects of ISO in vivo and in vitro, and explored the underlying mechanisms. Yeast extract-induced hyperuricemia animal model as well as hypoxanthine and xanthine oxidase (XOD) co-induced high uric acid L-O2 cell model and enzymatic experiments in vitro were selected. The XOD activity and uric acid (UA) level were inhibited after the treatment of ISO in vitro and in vivo. Furthermore, serum creatinine (CRE) and blood urea nitrogen (BUN) levels were also significantly reduced and liver damage was recovered in pathological histology after the ISO administration in hyperuricemia animal model. The results of mechanism illustrated that protein expressions such as XOD, toll-like receptor 4 (TLR4), cathepsin B (CTSB), NLRP3, and its downstream caspase-1 as well as interleukin-18 (IL-18) were markedly downregulated by ISO intervention in vitro and in vivo. Our results suggest that ISO exerts a urate-lowering effect through inhibiting XOD activity and regulating TLR4-NLRP3 inflammasome signal pathway, thus representing a promising candidate therapeutic agent for hyperuricemia. Graphic abstract Both animal models and in vitro experiments suggested that ISO may effectively lower uric acid produce. The mechanism might be the inhibition of XOD activity and NLRP3 inflammasome of upregulation.
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JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 56
·期 6
·4254-4265
·
IF 3.553
Zhang Wenqiang,Zhu Xiaotong,Liang Liang,Yin Peng,Xie Peitao,Dastan Davoud,Sun Kai,Fan Runhua,Shi Zhicheng
With the rapid development of miniaturization and high integration of electronic devices, increasing attention has been paid to the exploration of dielectric composites with further improved dielectric permittivities. Herein, a unique design of high dielectric permittivity composites consisting of three-dimensional porous W-WO 3 /BaTiO 3 foams hosted in epoxy matrix is proposed. It is demonstrated that the introduction of W-WO 3 /BaTiO 3 foams into the epoxy matrix results in substantially improved dielectric permittivities in comparison with the epoxy matrix. Meanwhile, low loss which is comparable to that of the epoxy matrix is well maintained. Interestingly, obviously enhanced dielectric permittivities and greatly depressed loss are concurrently achieved via increasing the oxidation temperature. In particular, the composite with 53.1 wt% W-WO 3 /BaTiO 3 foam oxidized at 1300 °C exhibits a high dielectric permittivity of ~ 536 and a low loss tangent of ~ 0.05@10 kHz which are about 149 and 1.5 times those of the epoxy matrix, respectively. It is believed that the strong interfacial polarization and the numerous equivalent micro-capacitors result in the significantly improved dielectric permittivities. The finite element simulation results reveal that the formation of the WO 3 shell on the surface of W can effectively weaken the leakage current density, yielding the sharply depressed loss. This work provides a new strategy to design polymer composites with simultaneous high dielectric permittivity and low loss, and the strategy could also be applicable to the exploration of other high-performance dielectric composites.
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Nano Research
·
2021
·Vol. 14
·期 8
·2689-2696
·
IF 8.897
Luo Feng-Qin,Chen Guojun,Xu Wei,Zhou Daojia,Li Jia-Xian,Huang Yong-Cong,Lin Run,Gu Zhen,Du Jin-Zhi
Glucose-responsive insulin delivery systems show great promise to improve therapeutic outcomes and quality of life for people with diabetes. Herein, a new microneedle-array patch containing pH-sensitive insulin-loaded nanoparticles (NPs) (SNP(I)) together with glucose oxidase (GOx)- and catalase (CAT)-loaded pH-insensitive NPs (iSNP(G+C)) is constructed for transcutaneous glucose-responsive insulin delivery. SNP(I) are prepared via double emulsion from a pH-sensitive amphiphilic block copolymer, and undergo rapid dissociation to promote insulin release at a mild acidic environment induced by GOx in iSNP(G+C) under hyperglycemic conditions. CAT in iSNP(G+C) can further consume excess H 2 O 2 generated during GOx oxidation, and thus reduce the risk of inflammation toward the normal skin. The in vivo study on type 1 diabetic mice demonstrates that the platform can effectively regulate blood glucose levels within normal ranges for a prolonged period.
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Nano Research
·
2020
·Vol. 14
·期 8
·2574-2583
·
IF 8.183
Zhao Xiaojuan,Wan Houzhao,Liang Pei,Wang Nengze,Wang Cong,Gan Yi,Chen Xu,Tan Qiuyang,Liu Xiang,Zhang Jun,Wang Yi,Wang Hanbin,Wang Hao
High-rate battery-type cathode materials have attracted wide attention for advanced battery-supercapacitor hybrid (BSH) devices. Herein, a core-shell structure of the hollow mesoporous carbon spheres (HMCS) supported NiSe 2 nanosheets (HMCS/NiSe 2 ) is constructed through two-step reactions. The HMCS/NiSe 2 shows a max specific capacity of 1,153.5 C·g −1 at the current density of 1 A·g −1 , and can remain at 774.5 C·g −1 even at 40 A·g −1 (the retention rate as high as 67.1%) and then the HMCS/NiSe 2 electrode can keep 80.5% specific capacity after 5,000 cycles at a current density of 10 A·g −1 . Moreover, the density functional theory (DFT) calculation confirmed that the introduction HMCS into NiSe 2 made adsorption/desorption of OH − easier, which can achieve higher rate capability. The HMCS/NiSe 2 //6 M KOH//HMCS hybrid device has energy density of 47.15 Wh·kg −1 and power density of 801.8 W·kg −1 . This work provides a feasible electrode material with a high rate and its preparation method for high energy density and power density energy storage devices.
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AAPS PHARMSCITECH
·
2020
·Vol. 22
·期 1
·1-9
·
IF 2.401
Zhang Lu,Li Yingying,Wei Fang,Liu Hang,Wang Yushuai,Zhao Weiman,Dong Zhiyong,Ma Tao,Wang Qingqing
Salmon calcitonin (sCT) is a polypeptide drug, possessing the ability to inhibit osteoclast-mediated bone resorption. Just like other bioactive macromolecules, sCT is generally administered to the patients by either injection for poor compliance or through nasal spray for low bioavailability, which limits its use as therapeutic drugs. In the present study, to overcome the limitations of the conventional routes, two new dissolving microneedle arrays (DMNAs) based on transdermal sCT delivery systems were developed, namely sCT-DMNA-1 (sCT/Dex/K90E) and sCT-DMNA-2 (sCT/Dex-Tre/K90E) with the same dimension, meeting the requirements of suitable mechanical properties. An accurate and reliable method was established to determine the needle drug loading proportion in sCT-DMNAs. The stability study exhibited that the addition of trehalose could improve the stability of sCT in DMNA under high temperature and humidity. Further, in vivo pharmacodynamic study revealed that DMNA patch could significantly enhanced relative bioavailability to approximately 70%, and the addition of trehalose was found to be beneficial for sCT transdermal delivery. Therefore, sCT-DMNA is expected to replace traditional dosage form, providing a secure, efficient, and low-pain therapeutic strategy for bone disorders.
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