MOLECULES
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2026
·Vol. 31
·期 17
·2970
·
IF 5.1
Sheng Liu,Feifei Wang,Shuran Xing,Guifang Chang,Shijie Li,Jianwen Bu,He Zhu,Litao Wang
Pork is highly perishable during storage, leading to enormous economic losses and potential food safety hazards. Anthocyanins (ANTs) possess excellent antioxidant and antibacterial activities, but their poor stability in practical applications limits their industrial application. To address these issues, a novel composite preservation film was prepared by the four-sided applicator solution casting method, using polylactic acid (PLA) and polybutylene adipate-co-terephthalate (PBAT) as matrix materials and ANTs@ZIF-8 as functional filler. Zeolitic imidazolate framework-8 (ZIF-8) encapsulated ANTs to enhance its stability and achieve sustained release, while the PLA/PBAT was selected for its good biodegradability, mechanical and barrier properties. The structure and properties of the PLA/PBAT/ANTs@ZIF-8 composite films were investigated, and the results showed that ANTs@ZIF-8 nanoparticles had stable dispersibility in the matrix, which effectively improved the compatibility between nanoparticles and the film matrix. The prepared composite films exhibited excellent tensile strength (TS), elongation at break (EAB) and water vapor transmission rate (WVTR), as well as good antibacterial activity againstE. coliandS. aureus. Furthermore, the practical pork preservation performance of the films was investigated, and the results demonstrated that the composite films could effectively reduce the pH value, water loss, color difference, total volatile basic nitrogen (TVB-N) content and malondialdehyde (MDA) content of fresh pork during storage, successfully extending the shelf life of pork to 12 days. This study develops a multifunctional, biosafe, and biodegradable PLA/PBAT composite film incorporated with ANTs@ZIF-8, providing a feasible strategy and scientific reference for the design and development of high-performance active biodegradable packaging materials.
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PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Qin Zikang,Deng Min,Shi Long,Yao Lu,Yang Lin,Jiang Wenju,Zheng Junfeng,Dai Zhongde
Defect engineering and the functionalization of metal-organic frameworks (MOFs) are acknowledged as an effective method to boost the separation capability of mixed-matrix membranes (MMMs). However, these processes are often carried out separately, making it difficult to achieve both objectives simultaneously. Herein, a polyethyleneimine (PEI)-induced simultaneous functionalization and defect engineering strategy is proposed, in which PEI is introduced during the synthesis of RHO-topology ZIF(Cu) to in situ generate structural defects through competitive coordination with Cu 2+ centers. PEI enhanced the interfacial compatibility between the filler and the Pebax matrix through hydrogen-bonding interactions and introduced a facilitated transport effect. Meanwhile, defect engineering exposed additional Cu 2+ Lewis acid sites capable of adsorbing CO 2 and generated additional transport pathways. The synergy between amine functionalization and defect engineering resulted in a substantial enhancement in the separation performance of the MMMs. Under humid conditions, the MMM containing 5 wt % PEI-RHO ZIF(Cu) presented a CO 2 permeability of 188.1 Barrer and a CO 2 /N 2 separation factor of 73.0, representing increases of 95.10% and 78.14%, respectively, relative to Pebax, and surpassing the 2008 Robeson upper bound. This integrated strategy, combining defect engineering with amine functionalization, provides a promising avenue for the development of high-efficiency CO 2 capture MMMs.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Hai Chen,Lisa Mingzhe Sun,Tianqi Wang,Jinrui Zhou,Jiawei Sun,Zhenyao Wang,Xinping He,Chunhai Yi,Jiaxin Guo,Jin Shang,Alicia Kyoungjin An
Thermally activated ZIF-8 exhibits a narrowed bandgap of 2.19 eV. • PS@ZIF-8-T NFM achieves 98.1% PM 2.5 filtration with low pressure drop. • 90.4% formaldehyde degraded within 1 h under visible light. • 81.25% E. coli inactivation achieved after 30 min illumination. • Superhydrophobic surface (WCA 150.6°) ensures self-cleaning ability. Nanofiber membranes offer significant potential for air purification; however, conventional membranes are typically limited to particle filtration and lack functionality against bacteria or volatile organic compounds. To address this, this study fabricated a multifunctional photocatalytic nanofibrous membrane by electrospinning polystyrene (PS) with ZIF-8-T (the air-thermally treated ZIF-8) as a photocatalyst. ZIF-8-T has a specific functional group, isocyanate (-N=C=O), with a band gap of 2.19 eV and exhibits broad-spectrum photo-response properties (200–800 nm). The optimized membrane with a 150 wt% ZIF-8-T loading demonstrated excellent integrated performance: a high PM 2.5 filtration efficiency of 98.1%, rapid degradation of 90.4% formaldehyde within 1 h under illumination, and superhydrophobicity with a water contact angle of 150.6°. Moreover, it achieved an antibacterial rate of 81.25% against E. coli within 30 mins of light exposure. This work presents a viable strategy for designing MOF-based composite membranes that integrate efficient filtration, photocatalytic degradation, and antibacterial functions for advanced air purification. Download: Download high-res image (261KB) Download: Download full-size image
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Food Chemistry-X
·
2026
·
IF 9.2
Xinyu She,Qian Zhou,Jingjing Song,Bin Wu,Na Xia,Chao Li,Siming Zhu
Lavender essential oil (LEO) has strong antibacterial and antioxidant properties, but its volatility limits practical use in fruit preservation. To address this limitation, we developed a pH-responsive delivery system (LEO@HZIF-8) using tannic acid (TA)-etched hollow ZIF-8 (HZIF-8) to enable controlled release of LEO. Mild etching generated a hollow structure that increased LEO encapsulation efficiency to 68.96%. Results indicate that LEO@HZIF-8 nanoparticles retain a well-defined crystalline structure and release LEO rapidly under acidic conditions, with a release rate of 73.36% at pH 4.5 after 72 h. Furthermore, LEO@HZIF-8 exhibited strong antioxidant activity, with DPPH and ABTS radical-scavenging rates of 85.48% and 78.24%, respectively, and significant antibacterial activity. When incorporated into a sodium alginate/zein (SA/Zein) coating, LEO@HZIF-8 extended the shelf life of white apricots to 63 days and effectively delayed decay, weight loss, and firmness loss. This study demonstrates an efficient pH-responsive delivery strategy for plant essential oils in freshness preservation and provides a basis for developing next-generation smart, eco-friendly active food packaging materials.
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高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·123101
·
IF 7.5
Deyi Han,Lin Ding,Shujuan Yang,Yong Zhang,Haichuan Zhang
This study reports the one-step in-situ assembly of a polydopamine (PDA)@ZIF-8 functional layer on polyethersulfone (PES) ultrafiltration (UF) membranes for high-flux, antifouling dye/salt separation. Leveraging the synergistic effect of dopamine (DA) self-polymerization and the in-situ growth of ZIF-8 during the nonsolvent-induced phase separation (NIPS) process, a highly integrated PDA@ZIF-8 functional layer was successfully constructed on the PES membrane surface. Strong coordination and chelation interactions among Zn 2 + ions, the catechol moieties of PDA, and 2-methylimidazole (2-MIM) increase the casting solution viscosity, triggering delayed demixing and promoting the migration of hydrophilic precursors toward the membrane interface. Structurally, the in-situ assembly of PDA@ZIF-8 significantly increased the selective layer thickness from 4.73 μm to 33.10 μm. The resulting ultrafiltration membrane exhibited exceptional separation efficiency, delivering a Congo Red (CR) rejection rate of over 99.5% while maintaining a salt rejection rate under 5%, enabling the efficient fractionation of dyes and salts. A high pure water flux of 455 L·m −2 ·h −1 at 0.1 MPa is attained, which is attributed to the enhanced surface hydrophilicity and the intrinsic sub-nanometer microporous channels of ZIF-8. Furthermore, the functionalized layer demonstrates remarkable antifouling properties toward anionic dyes, with a stable flux recovery ratio (FRR) exceeding 85% after multiple cycles of CR filtration. This research presents an effective membrane preparation strategy that enhances separation performance while ensuring excellent long-term antifouling stability.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Qianqian Yu,Jingxiao Yu,Qing Yang,Da-Wen Sun,Hongbin Pu
A novel chiral hierarchical porous ZIF-8/Au@Ag bipyramids SERS substrate (HPZA) was constructed. • Developing a dual-chiral synergistic enhancement strategy. • Pioneering the integration of deep learning algorithm with this chiral SERS platform. The widespread use of combined pesticides has led to increasing concerns over mixed pesticide residues in food, posing significant challenges for rapid and reliable detection. Herein, we develop an intelligent surface-enhanced Raman spectroscopy (SERS) platform by integrating a bichiral nanostructured substrate with deep learning for multiplex pesticide analysis. A hierarchical porous chiral ZIF-8 (HPZ) was engineered using L-histidine as a pore-expanding agent and assembled with L-cysteine-directed Au@Ag bipyramids to form the HPZA substrate, enabling synergistic adsorption enrichment and electromagnetic enhancement. The resulting platform exhibits high sensitivity and stability, achieving a detection limit of 9.54 ng/mL for quinalphos in citrus samples. Moreover, when coupled with a fully connected neural network (FCNN), it enables accurate discrimination of multiple pesticides and their mixtures, reaching an identification accuracy of 93.33%. This work presents an integrated material–algorithm strategy for rapid and intelligent detection of pesticide residues, offering a promising approach for food safety monitoring. Download: Download high-res image (105KB) Download: Download full-size image
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Food Analytical Methods
·
2026
·Vol. 19
·期 9
·248
·
IF 3
Qin Shili,Zhao Dongsheng,Jin Fenglong,Qin Yuting,Liang Xinyu,Liu Jingwen,Chu Hongtao,Gao Lidi,Zhao Ming
In this study, the octahedral core–shell ZIF-8@UiO-66-NH 2 composite, exhibiting high crystallinity, microporous structural properties and multifunctional groups, was synthesized, characterized, and applied for the first time as stationary phase in capillary electrochromatography. The baseline separation of four groups containing 14 analytes was achieved within 11.6 min, with resolution of at least 1.51. Compared to the individual components of ZIF-8 and UiO-66-NH 2 used as chromatographic stationary phase, the bonded capillary column based on ZIF-8@UiO-66-NH 2 exhibited the improvement in resolution and column efficiency (theoretical plate numbers) ranging from 68.14 to 918.75% and from 3.92 to 398.31%, respectively, and sample loading capacity increased by ≥ 26.8%. Furthermore, an accurate, rapid, and reliable electrochromatography method was developed for the qualitative and quantitative analysis of thiamphenicol and florfenicol in pork meat. The limits of detection and quantification for thiamphenicol were 0.34 μg/mL and 1.75 μg/mL, and for florfenicol, 1.00 μg/mL and 5.82 μg/mL, with sample recoveries in the range of 96.00 to 108.00% and the standard deviations less than 4.59%. This work not only confirmed the potential of MOF@MOF composite as high-performance stationary phases but also broadened the electrochromatography application in food inspection. Graphical
The alternative text for this image may have been generated using AI.
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Food and Bioprocess Technology
·
2026
·Vol. 19
·期 7
·346
·
IF 5.6
Li Changhao,Liu Ruiqi,Li Na,Yang Lingfan,An Guangying,Tian Tian,Li Huina,Wang Guangxian,Wang Songlei
Wolfberry, a medicinal and edible plant rich in nicotinamide adenine dinucleotide (NADH), is noted for its antiaging and antioxidant properties. However, the trace levels and instability of NADH present significant detection challenges. To overcome the inherent limitations of traditional electrochemical linear peak fitting, three machine learning algorithms were introduced: random forest, support vector machine regression (SVR), and long short-term memory neural networks. This pioneering approach established a complex nonlinear relationship model between concentration and response current, effectively mitigating high-concentration linear distortion and interference constraints within the detection system. The Shapley additive prediction method (SHAP) was ultimately employed to quantify the contribution of each electrode potential to the prediction of response currents. This study developed an electrochemical biosensor based on a NbC@NC-ZIF-8/ADH heterojunction substrate, combined with a machine learning–based nonlinear modeling approach, achieving precise quantitative detection of NADH concentration in wolfberry. It exhibits a broad detection range from 1 μM to 1.5 mM, with a detection limit as low as 0.075 μM. The linear prediction model achieved R 2 = 0.976. After constructing a nonlinear model using the SVR machine learning algorithm, the NADH concentration detection accuracy improved to R 2 = 0.996, significantly enhancing detection precision. SHAP analysis indicated that the 0.264 V potential contributed most significantly to the model output. This study established a trace detection research framework encompassing “heterojunction material preparation–density functional theory analysis–nonlinear model construction–SHAP interpretability analysis,” providing a reliable solution for the rapid and accurate detection of NADH in wolfberry. It demonstrates broad application prospects in the field of bioanalysis.
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Food Quality and Safety
·
2026
·
IF 4.9
Li Hao,Shu Changge,Zhou Yunfan,Zhang Kang,Wang Yixiu
Plant essential oil is acclaimed for its antibacterial and antioxidant qualities; however, it presents challenges in terms of stability and compatibility with natural polymers. This investigation centers on the application of single-crystalline ordered macro-microporous ZIF-8 (SOM-ZIF-8) for loading clove essential oil (CEO), which was later combined with starch/gellan gum to fabricate starch-based packaging films. This study meticulously explores the structural and property aspects of these films. SOM-ZIF-8, distinguished by its macroporous structure, reveals a CEO loading capacity of 660.6±2.4 mg/g. Starch-based films containing CEO@SOM-ZIF-8 demonstrate outstanding mechanical robustness, superior gas barrier properties, low moisture absorption, pronounced antioxidant activity, and potent antibacterial efficacy against key pathogens (Escherichia coli and Staphylococcus aureus). Blueberries packaged with the 4% (mass fraction) CEO@SOM-ZIF-8 film maintained the highest firmness (18.7±0.2 N) and soluble solids content (5.4%±0.1%). The film with 4% CEO@SOM-ZIF-8 consistently preserved the highest total phenol content (110.92 mg/L, P<0.05), a result significantly superior to the PE group and directly correlated with its efficacy in delaying quality deterioration by suppressing metabolic and microbial activity in blueberries. A key feature is the gradual and sustained release of CEO from CEO@SOM-ZIF-8, with release kinetics accurately described by the Ritger-Peppas equation. Importantly, the pH-responsive nature of this release provides a major advantage for preserving fruits and vegetables by extending shelf life.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Weiqing Xiong,Yu Yang,Lei Huang,Yue Zhang,Xiao Li
The accurate detection of trace pharmaceuticals and pesticides in aquatic environments remains a formidable analytical challenge, primarily due to ultralow contaminant concentrations, complex matrix interferences, and the structural similarity among many target analytes—factors that severely compromise selectivity and reliability in conventional sensing approaches. Surface-enhanced Raman scattering (SERS) offers a powerful alternative owing to its exceptional sensitivity and molecular fingerprinting capability. However, its practical deployment in real-world water samples has been impeded by insufficient selectivity and inadequate signal discrimination for structurally analogous compounds. To overcome these limitations, we present an innovative core-shell SERS substrate—gold superparticles encapsulated within a zeolitic imidazolate framework-8 (denoted GSPs@ZIF-8)—engineered to synergistically combine molecular preconcentration, matrix exclusion, and electromagnetic field enhancement. The porous ZIF-8 shell selectively enriches trace thiazole/imidazole-type analytes while excluding interfering species, thereby addressing the dual challenges of low abundance and matrix complexity. Meanwhile, the precisely controlled nanogaps between GSPs generate intense and uniform “hot spots”, delivering an enhancement factor of up to 3.01 × 10 8 and enabling a detection limit as low as 0.1 nM for 2-mercaptobenzothiazole (MBT). Critically, the GSPs@ZIF-8 platform achieves discrimination and simultaneous quantification of three highly similar compounds—MBT, 5-amino-2-mercaptobenzothiazole (AMT), and 2-mercaptobenzimidazole (MBI)—in mixed aqueous solutions. This work establishes a robust, selective, and ultrasensitive SERS strategy for monitoring structurally homologous contaminants in complex environmental matrices, paving the way toward practical on-site water quality assessment.
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DYES AND PIGMENTS
·
2026
·
IF 3.9
Daoxin Wu,Shuyao Li,Jingkun Sun,Yang Qiu,Zhaoyang Wu,Wenzhao Liu
A novel ZIF-8/carboxylated polyurethane 3D photonic crystal sensor is developed for putrescine and cadaverine detection. • Dual sensing mechanism: ZIF-8 enables size-selective adsorption and refractive index modulation, while PU provides carboxyl-amine acid-base swelling. • The optimal sensor (n BDO :n DMBA = 3:7) achieves a low detection limit of 0.86 ppm for putrescine and high selectivity over common VOCs. • Synergistic signal amplification yields a maximum reflection peak shift of 27.02 nm at 100 ppm. Rapid on-site detection of biogenic amines (e.g., putrescine and cadaverine) is critical for food freshness monitoring. Herein, we report a three-dimensional photonic crystal (3DPC) sensor composed of ZIF-8 nanoparticles and carboxyl-functionalized polyurethane (PU). The PU matrix, with tunable carboxyl content via DMBA/BDO ratio, enables acid-base induced swelling upon exposure to amine vapors, while ZIF-8 provides size-selective enrichment and refractive index modulation. The sensor with an optimal n BDO :n DMBA molar ratio of 3:7 exhibits a low detection limit of 0.86 ppm for putrescine, a sensitivity of 0.2384 nm/ppm, and excellent selectivity over common VOCs. The synergistic dual-mechanism (swelling + refractive index change) yields a maximum reflection peak shift of 27.02 nm at 100 ppm. Moreover, the sensor shows moderate response time (2.5 min) and good long-term stability (35 days). This work provides a new strategy for integrating MOF adsorption and polymer swelling into a visual sensing platform for biogenic amines.
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高影响因子
BIOMATERIALS
·
2026
·
IF 13.6
Canyi Chen,Qinqing Tang,Qinyao Xu,Dehui Feng,Qiang Luo,Bin Xu,Hanyuan Zhang,Tingting Zhao,Weijun Fang
Targeted autophagy regulation holds great promise for antitumor therapy, whereas conventional single-modal autophagy interventions easily induce compensatory escape of tumor cells and fail to transform protective autophagy into a lethal phenotype. In this study, a near-infrared (NIR)-responsive polypyrrole/zeolitic imidazolate framework-8 (PPy/ZIF-8) nanoparticle was successfully fabricated. This nanoplatform enables synergistic and precise regulation of autophagic flux, which amplifies upstream autophagy activation and blocks downstream autophagic pathways simultaneously. The incorporation of PPy endows the nanoparticle with excellent near-infrared absorption capability and photothermal effects. It boosts interfacial electron transfer and optimizes electron-hole separation, further enabling the nanoparticles to possess ROS generation ability. Under 808 nm laser irradiation, the generated ROS and zinc ions induce mitochondrial damage to amplify upstream autophagic signals, whereas the photothermal effect impairs lysosomal function and blocks the downstream degradation of autophagosomes. This dual regulatory strategy causes pathological accumulation of autophagosomes and ultimately triggers autophagic cell death in tumor cells. This work validates the feasibility of integrated autophagy regulation and provides a facile and versatile strategy for the design of advanced multimodal antitumor nanotherapeutics.
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高影响因子
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