JOURNAL OF SEPARATION SCIENCE
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2013
·Vol. 36
·期 15
·2530-2537
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IF 2.591
Maria del Mar Barrios-Romero,Agustín G. Crevillén,José Carlos Diez-Masa
This work describes the development of an SDS-gel electrophoresis method for the analysis of major whey proteins (α-lactalbumin, β-lactoglobulin, and BSA) carried out in SU-8 microchips. The method uses a low-viscosity solution of dextran as a sieving polymer. A commercial coating agent (EOTrol LN) was added to the separation buffer to control the EOF of the chips. The potential of this coating agent to prevent protein adsorption on the walls of the SU-8 channels was also evaluated. Additionally, the fluorescence background of the SU-8 material was studied to improve the sensitivity of the method. By selecting an excitation wavelength of 532 nm at which the background fluorescence remains low and by replacing the mercury arc lamp by a laser in the detection system, an LOD in the nanomolar range was achieved for proteins derivatized with the fluorogenic reagent Chromeo P540. Finally, the method was applied to the analysis of milk samples, demonstrating the potential of SU-8 microchips for the analysis of proteins in complex food samples.
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SENSORS AND ACTUATORS B-CHEMICAL
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2026
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IF 8.3
Xuhan Wang,Xiaoning Meng,Wei Gao
Hydrophobic ZIF-8 was grown on PdPt/WO 3 for room‑temperature H 2 detection under 90% RH. • ZPPW-2.0 sensor achieved ultrahigh response (15976.29) to 5000 ppm H 2 at 25℃ under 90% RH. • Dual sieving provided excellent selectivity against interfering gases. • Red‑light excitation enhanced sensitivity via oxygen‑vacancy activation. • Multi‑mechanism design ensured humidity‑tolerant and stable performance. This study presented the development of a room-temperature hydrogen (H 2 ) gas sensor, designated ZPPW-2.0, capable of operating reliably under high-humidity conditions. The sensor structure was constructed by growing hydrophobic zeolitic imidazolate framework (ZIF-8) on a PdPt-modified WO 3 sensing film. This configuration enabled a synergistic surface regulation mechanism involving molecular sieving, surface defect engineering and photoexcitation-enhanced surface reactivity. Under ambient operating conditions (25°C, 90% relative humidity), the sensor exhibited a remarkable response of 15976.29 to 5000 ppm H 2 , a response time of 8 s, excellent repeatability, long-term stability, and outstanding selectivity. Furthermore, illumination with 655–660 nm red light could enhance performance. The observed high performance was attributed to the synergistic enhancement by surface defect states, effective exposure of surface active sites, inhibition of surface water competition, and molecular sieving. This work highlighted the central role of surface reaction, and interfacial regulation in designing reliable room-temperature H 2 sensors for humid environments. Download: Download high-res image (274KB) Download: Download full-size image
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Journal of Materials Chemistry A
·
2022
·Vol. 10
·期 24
·13013-13020
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IF 14.511
Zikuan Zhang,Haixia Zhang,Ying Hou,Peizhi Liu,Xiaodong Hao,Yanzhen Liu,Bingshe Xu,Junjie Guo
Perovskite oxide based electrocatalysts hold great promise as potential alternatives to platinum-based electrocatalysts for the oxygen reduction reaction (ORR), and thus have attracted tremendous research interest. Nevertheless, exploring high-performance ORR catalysts to improve pivotal reaction kinetics particularly in an acidic environment remains a great challenge. Herein, an N-doped porous nanocarbon framework supported perovskite CeFeO3 nanoparticle catalyst (Ce–Fe/NC) is fabricated from a predesigned Ce–Fe-doped ZIF-8 by a facile one-step route. The prepared catalyst displays a dodecahedral morphology with a large number of mesopores, which facilitate confining the aggregation of the CeFeO3 nanoparticles and promoting mass transport in the electrochemical process. Meanwhile, the introduced oxygen vacancies play a role in manipulating the local structure of the Fe active sites in CeFeO3, and boost their ORR performance. Impressively, the Ce–Fe/NC catalyst shows outstanding ORR half-wave potentials in pH universal electrolytes (0.913 V in alkaline and 0.791 V in acidic electrolytes), as well as good durability. A zinc–air battery utilizing the Ce–Fe/NC material as the air electrode offers an excellent specific capacity of 804 mA h g−1 and a long-term stability of 105 h in galvanostatic charge–discharge. This work provides a promise of non-precious-metal electrocatalysts with good prospects for realistic applications in zinc–air batteries and fuel cells.
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FOOD CHEMISTRY
·
2024
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IF 8.5
Hongyuan Zhao,Mengyuan Zhao,Jiale Han,Zirong Li,Jing Tang,Zhankui Wang,Guifang Wang,Sridhar Komarneni
Gallic acid (GA) has important application value in several fields of foods, medicines, and chemical engineering. However, the excessive intake of GA may cause gastrointestinal discomfort and nerve damage. Herein, an economical room-temperature fabrication strategy was reported for the preparation of zeolitic imidazolate framework-8 (ZIF-8) nanoparticles combined with graphitized and carbonylated carbon nanotubes (GCMCN) networks, which were used to achieve the ultrasensitive electrochemical detection of GA. The GCMCN@ZIF-8 nanocomposite modified electrode realized an accurate and rapid analysis of GA (Linear concentration range: 0.1–20 μM, LOD: 4.77 nM). GCMCN networks with graphitization and carboxylation boosted the electrical conductivity of electrode modification layer and enhanced the electrochemical interface area between sensing electrode and electrolyte. ZIF-8 nanoparticles with more active interaction sites and high porosity possessed high adsorption capacity for GA molecules. The fabricated electrochemical sensing platform exhibited good GA quantitative analysis property in food samples (Recovery: 93.88–106.73 %, RSD: 1.04–3.73).
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ACS Applied Materials & Interfaces
·
2024
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IF 8.3
Yongmei Ge,Liqiu Hu,Jiayi Liu,Fenbo Ma,Jiarong Zhang,Yansong Wang,Bin Tang,Shuaishuai Cao
The repair of large bone defects poses a significant challenge in orthopedics. Polyetheretherketone (PEEK) is a promising bone substitute, while it suffers a lack of bioactivity. Although several studies have been performed to further improve the bioactivities of PEEK by various surface modifications, PEEK offering long-term, multifaceted biofunctionalities remains still desired. In this study, we introduced metal–organic frameworks (MOFs), specifically ZIF-8 loaded with celecoxib (ZIF-8(CEL)), onto the PEEK surface through dopamine adhesion. The resulting PEEK@ZIF-8(CEL) aims to achieve long-term stable release of Zn ions and CEL for enhanced bone integration. Material characterization and biological experiments confirmed the successful integration of ZIF-8(CEL) onto PEEK and its positive biomedical effects, including creating a positive bone immunological environment and promoting bone growth. This study demonstrates the potential of PEEK@ZIF-8(CEL) as a novel repair material for large bone defects, offering a promising alternative in orthopedic applications.
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ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Luping Feng,Enjun Chen,Jianghong Wang,Xinfeng Li,Yujie Fan,Leyao Jin,Peisong Tang,Lixiang Zhang
A simulated sunlight-driven photoelectrochemical (PEC) sensor has been developed for quantitative analysis of hydrogen sulfide (H 2 S) with “signal-on” output by Hg 2+ -integrated ZnS nanocubes (Hg 2+ @ZnS NCs). Herein, hollow ZnS NCs were firstly prepared by the ZIF-8-derived soft-template method. Subsequently, Hg 2+ probing ions were doped into the porous structures of these ZnS NCs through an adsorption reaction, yielding Hg 2+ @ZnS NCs. It was observed that Hg 2+ @ZnS-based PEC sensor could exhibit slightly enhanced PEC responses over pristine ZnS, attributed to the adsorption of Hg 2+ on ZnS surface, which may modulate surface states/defects and band structures to suppress surface recombination. More importantly, after the addition of H 2 S, the in-situ growth of HgS@ZnS with a type-II heterojunction enables enhanced photocurrent response in developed sensor by promoting efficient spatial charge separation and transfer. A PEC sensing platform with exceptional sensitivity and selectivity has been established for H 2 S quantification, covering a linear range of 0.05–10 nM and a detection limit of 32 pM, which may serve as a guideline for the design of PEC sensors for real-world H 2 S analysis in complex matrices like environmental wastewater and industrial waste gas.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2025
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IF 21.1
Peng Wang,Zijing Liu,Yanwei Xing,Bin Fan,Yulong He,Ting Gao,Wenlei Zhang,Yunfei Gao,Shuang Wang,Jinping Li
Electrocatalytic nitrogen reduction reaction (ENRR) is considered as a potential pathway for green synthesis of ammonia. However, the kinetic barriers of ENRR remain a tough challenge, which is imperative to design high effective electrocatalysts for accelerated activation of N N. Herein, the FeS/ZnS/ZIF-8-L with rich heterogeneous interfaces was successfully fabricated by governing the ordered lasso arrangement of Fe and Zn nodes in Fe-2MIM/ZIF-8-L precursor, where Fe and Zn were separately fixed in the confined space of ZIF-8-L and Fe-2MIM. Such intertwined Fe-2MIM/ZIF-8-L structure was beneficial to control the location and concentration of FeS and ZnS after sulfidation pyrolysis. The high-efficiency FeS/ZnS/ZIF-8-L exposed more catalytic active sites and possessed optimal electronic structure resulting in the lowered energy barrier of ENRR and the enhanced adsorption and activation of N 2 , which confirmed by experimental and theoretical characterization results. As a result, FeS/ZnS/ZIF-8-L displayed an optimal NH 3 yield rate of 89.52 μg h −1 mg −1 and Faradaic efficiency of 16.78 %, which surpassed most reported heterostructured ENRR catalysts. Our findings shed a new insight to govern the interfaces density of heterostructured electrocatalysts by predesigning the location of two metals in precursor, which can motivate an in-depth exploration to advanced catalysts for various electrocatalytic reactions.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2025
·
IF 8.3
Ketao Wang,Shijie Jiang,Ranjie Zeng,Long Zeng,Yuting Ou,Jieying Lv,Xiaohui Su,Bin Chi,Tiejun Wang,Dai Dang
Constructing self-supporting electrodes with ordered channels is critical to enhancing mass transport and ensuring structural integrity in practical hydrogen evolution reaction (HER) applications. Herein, we develop a binder-free self-supporting electrode using freestanding carbonized wood (CW) as a three-dimensional scaffold. ZIF-8 was utilized as a linker for in-situ growth to form CW@ZIF-8 materials. This composite was then impregnated with molybdate salts and subjected to a secondary carbonization process, resulting in the formation of electrically active Mo 2 C nanoparticles within the ordered channels. The resulting Mo 2 C/N–C/CW electrode exhibits excellent HER performance, which requires only 106.5 mV overpotential in alkaline and 130.9 mV in acidic media at 10 mA cm −2 . The enhanced performance is attributed to the hierarchical CW framework, which not only promotes uniform Mo 2 C dispersion but also facilitates electrolyte diffusion. This strategy offers a scalable route toward cost-effective, efficient, and durable self-supporting HER electrodes suitable for both acidic and alkaline environments.
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JOURNAL OF MEMBRANE SCIENCE
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2026
·
IF 8.8
Yitong Wang,Yanhua Tian,Jingde Li,Liping Zhao,Yanqin Yang
Mixed matrix membranes (MMMs) composed of polymers and metal-organic frameworks (MOFs) can effectively break the trade-off between selectivity and permeability of pure polymer membranes, thus holding great potential for the development of high-efficiency gas separation membranes. Nevertheless, structural mismatches between polymer matrix and MOF particles easily cause interfacial defects and filler aggregation, which severely hinder efficient gas separation. In this work, a novel interfacial bonding strategy is proposed. Specifically, an amidoxime-modified polymer of intrinsic microporosity (AOPIM-1) with similar structure to polymer matrix (PIM-1) is firstly used to modify and encapsulate the zeolitic imidazolate framework-8 (ZIF-8), generating a composite filler AO@ZIF. Within the resultant MMMs, due to the Zn-N coordination bonds and hydrogen bonds between ZIF-8/AOPIM-1 and PIM-1/AOPIM-1, respectively, low-defect interfaces are obtained. The optimized interfacial compatibility further achieves efficient CO 2 /N 2 separation performance. Particularly, when the filler loading is 2.5 wt%, the CO 2 /N 2 selectivity of the AO@ZIF-2.5/PIM-1 membrane increases by 72.8% and 46.0% compared with pristine PIM-1 and ZIF-2.5/PIM-1 membrane, exceeding the 2008 Robeson upper bound and approaching the 2019 Robeson upper bound. Moreover, the resultant membranes also possess outstanding mechanical properties, anti-plasticization capacity, and excellent anti-physical aging stability. This study provides a feasible strategy for interfacial design and performance optimization of high-performance MOF/polymer MMMs toward advanced gas separation.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Juanjuan Wang,Yang Cao,Shaoyi Li,Yunxiao Wen,Jian Yang
Carbon-based electrocatalysts exhibit excellent oxygen reduction reaction (ORR) activity. Their abundant porous structures and diverse active sites provide accessible mass transfer channels and high current densities during electrocatalysis. Herein, a series of polyhedral porous carbon materials integrated with N-doped carbon nanotubes (CNTs) were fabricated by pyrolyzing precursors under an Ar atmosphere. These precursors were obtained by selectively pre-etching ZIF-8, followed by immersion in Fe ions. The amount of etching agent and Fe during precursor preparation significantly influenced the morphologies and the abundance of CNTs. The optimized sample, denoted as FeN x /Fe@NC-20:6, displayed abundant CNTs intimately connected to the polyhedral porous carbon. It delivered a half-wave potential of 0.92 V ( vs . RHE) and a limiting current density of 5.2 cm −2 for ORR. Furthermore, Zn-air batteries assembled with the FeN x /Fe@NC-20:6 catalyst demonstrated outstanding discharge performance, with an open-circuit voltage of 1.522 V, a specific capacity of 803 mAh g −1 , and a peak power density of 197.4 cm −2 . Therefore, the pre‑etching strategy represents an effective route to design high‑performance, non‑precious‑metal ORR catalysts, thereby facilitating the development of sustainable energy devices. Download: Download high-res image (248KB) Download: Download full-size image Acid-etching of ZIF-8 is an interesting strategy for promoting the CNTs growth via the Fe ions injecting in the precursor. The obtained hybrid catalyst with polyhedral porous and CNTs exhibits excellent ORR performance.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zile Wang,Yuliang Xu,Shuai Zhang,Sihan Wang,Ke Han,Zhiyue Feng,Chujun Liu,Tao Peng,Haiyang Jiang
In order to explore a cost-effective and environmentally friendly strategy for pretreatment, this study established a pH-responsive method based on zeolitic imidazolate framework-8 (ZIF-8). The saturated adsorption capacity of target analytes (atropine and scopolamine) could reach 44.56 and 33.55 mg/g. Based on the characterization combined with the computer simulation, it is concluded that the adsorption mainly depends on electrostatic interaction, π-π stacking and hydrogen bonding. The adsorbed ZIF-8 can be used for immunoassay after acid-alkali treatment. By optimizing the conditions, the detection limit of the established pH-responsive immunoassay was 0.24 and 0.62 μg/kg in honey, the recovery rates were 92.9 %∼112.3 %, and the coefficient of variations were less than 22.7 %. The desorption process in this strategy does not rely on massive organic reagents, making it potentially cost-effective and environmentally friendly for analyzing analytes in complex matrices.
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LANGMUIR
·
2026
·
IF 3.9
Anh-Tuan Pham,Quan-Doan Mai,Thi Hanh Trang Dang,Thi Loan Ngo,Trung Thanh Nguyen,Pham Cong Thanh,Cong Thanh Dinh,Van Hoang Ong,Ta Ngoc Bach,Quang Hoa Nguyen,Trang Xuan Mai,Anh-Tuan Le
Surface-enhanced Raman scattering (SERS) is among the most sensitive molecular detection techniques, capable of reaching the single-molecule level. However, extending its utility beyond a narrow sensitive class of molecules is hampered by the difficulty of probing species with intrinsically weak Raman responses and poor affinity for noble metal substrates. Metal–organic frameworks (MOFs), with their high porosity and large surface area, are widely used to adsorb and enrich diverse molecules. Herein, we combine the high molecular capture capability of zeolitic imidazolate framework-8 (ZIF-8) with the localized surface plasmon resonances (LSPRs) of Ag nanoparticles (NPs), and successfully develop a plasmonic porous multicore@shell Ag@ZIF-8 nanostructure via a simple solvent-induced self-assembly approach, where AgNPs formed in methanol directly guide ZIF-8 growth, avoiding solvent-exchange steps and enabling scalable synthesis under ambient conditions. This hybrid architecture integrates the strong plasmonic response of multicore AgNPs with the highly porous ZIF-8 shell matrix capable of concentrating molecular analytes, thereby yielding a great enhancement in the SERS signal. Such a unique SERS substrate delivers consistent and superior detection performance for analytes of different sizes and metal affinities. By trapping analyte molecules within the porous three-dimensional ZIF-8 shell, the multicore@shell Ag@ZIF-8 platforms synergistically couple electromagnetic and adsorption-assisted chemical enhancement mechanisms. This design achieves SERS signal amplification of up to one, three, and even five orders of magnitude for methylene blue, thiram, and 4-nitrophenol, respectively, compared with bare-metal substrates, and enables ultrasensitive detection limits down to 10, 1, and 0.1 nM. Our study thus paves the way for the development of ultrasensitive, reliable, and scalable SERS substrates for a broad spectrum of molecular targets through rational design and facile synthesis.
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