Polymers
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2019
·Vol. 11
·期 2
·368
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IF 3.164
Hongxia Wang,Yu Liao,Ailiang Wu,Bing Li,Jun Qian,Fuyuan Ding
Environmentally friendly food packaging currently attracts much interest. Sodium trimetaphosphate (STMP) finds specialized applications in food, but it is rarely used as a crosslinking agent. In this study, STMP was used as a crosslinking agent to prepare chitosan/methylcellulose composite films. Both antibacterial and physicochemical properties of the composite film were improved by crosslinking with STMP. The crosslinked films, with good antibacterial activity (~99%), had increased tensile strength, a higher elongation at break, a lower swelling ratio and solubility, and a lower enzymatic degradation than the non-crosslinked films. Furthermore, the crosslinked films showed an excellent preservative effect on fresh-cut wax gourd after three days at room temperature. The obtained films crosslinked by STMP can be potentially applied to the food industry, such as food functional packaging, providing a novel alternative to traditional plastic packages.Keywords:sodium trimetaphosphate;chitosan/methylcellulose composite film;antibacterial activity;physicochemical property;food packaging
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RSC Advances
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2019
·Vol. 9
·期 11
·6254-6266
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IF 3.049
Ming-Ming Tu,Jing-Jie Xu,Yun-Ren Qiu
In this study, acrylic acid (AA) and sulfonated hydroxypropyl chitosan (SHPCS) were covalently grafted on the PSf membrane surface to improve its hemocompatibility. First, the modified AA-PSf membrane was obtained through the Friedel–Craft reaction between acrylic acid and the PSf membrane surface. Then, the modified SHPCS-AA-PSf membrane was prepared by grafting SHPCS onto the AA-PSf membrane surface via the dehydration acylation of the carboxyl group of the AA-PSf membrane with the amino group of SHPCS. ATR-FTIR and XPS measurements confirmed that the –COOH group and SHPCS were successfully grafted onto the surface of the PSf membrane. The modified PSf membranes showed suppressed platelet adhesion and lower protein adsorption (161 μg cm−2) compared with the pristine PSf membrane (341 μg cm−2). Hemocompatibility testing showed that modified membrane materials had a prolonged clotting time, plasma recalcification time (PRT), activated partial thromboplastin time (APTT), thrombin time (TT), and prothrombin time (PT). All of these results indicated that the surface modification of the PSf membrane with acrylic acid and SHPCS had good hemocompatibility and anticoagulant property.
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ANALYTICAL CHEMISTRY
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2019
·
IF 6.35
Luwei Zhang,Shujuan Ma,Yao Chen,Yan Wang,Junjie Ou,Hiroshi Uyama,Mingliang Ye
In the study of glycoproteomics with mass spectrometry, certain pretreatments of samples are required for eliminating the interference of nonglycopeptides and improving the efficiency of glycopeptides detection. Although hydrophilic interaction chromatography (HILIC) has been developed for enrichment of glycosylated peptides, a plethora of hydrophilic materials always suffered from large steric hindrance, great cost, and difficulty with modifications of high-density hydrophilic groups. In this work, a 1 mm thick biomimetic honeycomb chitosan membrane (BHCM) with honeycomb-like accessible macropores was directly prepared by the freeze-casting method as an adsorbent for HILIC. The N-glycopeptides from trypsin digests of immunoglobulin G (IgG), mixture of IgG and bovine serum albumin (BSA), and serum proteins were enriched using this material and compared with a commercial material ZIC-HILIC. The biomimetic membrane could identify as many as 32 N-glycopeptides from the IgG digest, exhibiting high sensitivity (about 50 fmol) and a wide scope for glycopeptide enrichment. A molar ratio of IgG trypsin digest to bovine serum albumin trypsin digest as low as 1/500 verified the outstanding specificity and efficiency for glycopeptide enrichment. In addition, 270 unique N-glycosylation sites of 400 unique glycopeptides from 146 glycosylated proteins were identified from the triplicate analysis of 2 μL human serum. Furthermore, 48 unique O-glycosylation sites of 278 unique O-glycopeptides were identified from the triplicate analysis of 30 μg deglycosylated fetuin digest. These results indicated that the chitosan-based membrane prepared in this work had great potential for pretreatment of samples in glycoproteomics.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
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2019
·Vol. 35
·期 3
·463-470
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IF 1.071
Zhang Di,Li Ning,Cao Shuai,Liu Xi,Qiao Mingwu,Zhang Pingan,Zhao Qiuyan,Song Lianjun,Huang Xianqing
Along with the growing severity of environment problem and energy crisis, it is inevitable to develop novel materials, which are contributed to the removal of hazardous pollutants from contaminated water. Herein, we reported a facile method for the preparation of free-standing chitosan/graphene oxide(CS/GO) composite sponges with low density, where CS/GO mixtures were first synthesized by the homogeneous reaction of chitosan and graphene oxide in aqueous acetic acid solution; then CS/GO sponges were obtained by lyophilizing the suspension, which were prefrozen at −20 °C and in liquid nitrogen successively. The obtained layered sponge showed good water-driven shape memory effect and was a good adsorbent of Co 2+ and Ni 2+ with a large adsorption capacity of 224.8 and 423.7 mg/g, respectively. Importantly, the successive adsorption-desorption studies employing CS/GO sponge indicated that the composite could be regenerated by HCl solution and reused in more than five cycles with regeneration efficiency beyond 80%. Also, the resultant sponge was explored as an exceptionally adsorbent for the removal of organic dye ( e.g. , methylene blue, MB).
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
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IF 4.784
Tao Zeng,Xue-qin Hu,Hao Wu,Jing-wen Yang,Hong-bin Zhang
Polysaccharide-modified flocculants as natural polymeric flocculants are receiving increased attention in the field of water treatment. In this study, a novel high-efficiency and ecofriendly flocculant was synthesized using dextran and chitosan. The flocculant-production method was based on a microwave-heating-initiated graft reaction. Results of Fourier transform infrared spectroscopy, nuclear magnetic resonance imaging, X-ray diffraction, elemental analysis, thermogravimetric analysis, and field-emission scanning electron microscopy confirmed that the grafting was successful. The influences of temperature, flocculant dosage, and pH on flocculation efficiency were investigated. Results indicated that 93.6% of the kaolin solid suspended particles were removed by the flocculant. Previous studies on the flocculation mechanism have shown that flocculation comprises adsorption bridging, charge neutralization, and sweeping flocculation. All these findings indicated the broad prospects of the improved dextran in treating industrial wastewater and developing novel high-performance flocculants.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
·
IF 4.784
Shuchun Gan,Bo Xu,Xiong Zhang,Jianhao Zhao,Jianhua Rong
Physically cross-linked double-network (DN) hydrogels are capturing more and more attention due to their good mechanical properties and self-recovery ability. However, they usually suffer from complicated preparation process and fussy performance regulation, which severely limit their applications in many fields. Herein, we fabricated a physically cross-linked poly(vinyl alcohol)-(2-hydroxypropyltrimethyl ammonium chloride chitosan) (PVA-HACC) DN hydrogels without organic solvents or toxic cross-linking agents via a simple two-step method of freezing/thawing and immersion processing. The effects of immersion time and concentration of Na 3 Cit solution on the structures and mechanical properties of the hydrogels were investigated. The obtained hydrogels exhibited excellent mechanical properties including high elastic modulus (1.44 MPa), high strength (a maximal tensile fracture stresses of 4.14 MPa and a maximal compressive stresses of over 70 MPa at 98% strain), and superior fracture toughness (17.09 MJ/m 3 ). In addition, good self-recovered property and anti-fatigue performance were realized for the hydrogels owing to the reversible HACC ionic networks. The preparation of PVA-HACC DN hydrogels offers a new guidance for the design and synthesis of environmentally friendly DN hydrogels with outstanding mechanical properties and broad application prospects.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
·
IF 4.784
Fang Wang,Qian Zhang,Xinxia Li,Kexin Huang,Wei Shao,Dawei Yao,Chaobo Huang
A simple method to fabricate redox-responsive composite hydrogel films via incorporating chitosan (CS) microspheres into carboxymethyl cellulose (CMC) hydrogel using a di-sulphide cross-linker cystamine dihydrochloride (CYS) have done in this paper. Dual drugs, an anticancer, 5-Fluorouracil (5-FU) and an antibiotic, Tetracycline Hydrochloride (TH) were used as model drugs. The prepared composite hydrogel films were characterized using FTIR, SEM, rheology measurement, mechanical and swelling tests. Our results showed that the well dispersed spherical CS microspheres endowed hydrogel film increased mechanical properties and swellability. In vitro drug release displayed an accelerated release under weak acidic or reducing media. The in vitro cytotoxicity and cell apoptosis studies showed the drug-loaded composite film caused enhanced inhibition to HepG2 cells in presence of glutathione (GSH). Moreover, the film has exhibited excellent antimicrobial efficacy against E.coli and Staphylococcus aureus . Therefore, our simple and effective dual drug-loaded system has the potential to be used for cancer therapy in the future.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
·
IF 4.784
Kewang Zheng,Wei Li,Wei Wang,Hujian Chen,Chaofan Huang,Qiaolin Ren,Caiqin Qin
Adsorption of metal impurities from transformer oil was studied using a novel porous membrane. A solution of N , O ‑carboxymethyl‑chitosan (CMC) and sodium phytate (SP) was blended to prepare a novel porous membrane for the metal impurities adsorption from transformer oil. The chemical structure of the membranes was characterised by their FTIR spectra, scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and video camera observations. The effects of the SP content of the membrane, contact time, and contact temperature on adsorption of copper, iron, and aluminium impurities were studied. The FTIR spectra and thermogravimetric curves of the membranes indicated good compatibility between CMC and SP. The SEM and video camera observations suggested that CMC-SP composite membranes had a mature, porous structure. The experimental results showed that the SP content significantly affected the adsorption capacity of a CMC membrane. The maximum adsorption percentages of elemental copper, iron, and aluminium were 88.12%, 82.35%, and 80.36% when the SP ratio was 80% at 60 °C.
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POLYMER TESTING
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2019
·
IF 2.943
Ning Yan,Xiao-Fang Wan,Xin-Sheng Chai
This paper reports on a novel method for rapid determination of the degree of deacetylation (DD) of chitosan samples by headspace gas chromatography (HS-GC). In this method, overdose of an acid is added to protonate the free amino groups in chitosan, which further reacts with bicarbonate (as an alkali titrant) in a close vial. Based on measuring the HS-GC signal for CO 2 vs. the volume of HCO 3 − added by a stepwise titration, two transition points can be obtained. The DD value is calculated by net volume of HCO 3 − consumed, i.e., by the R NH 3 + groups in chitosan. The results showed that the present method has a good measurement precision (RSD < 0.82%) and accuracy (relative differences < 6.46% when compared with the results measured by a reference method). Since the HS-GC can perform an automated sample reaction equilibration and measurement, it could be much more efficient than the existing methods in the batch sample analysis.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2019
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IF 3.571
Chi Yan,David Julian McClements,Yuqing Zhu,Liqiang Zou,Wei Zhou,Wei Liu
This paper attempted to construct a high internal phase emulsion (HIPE) through altering interfacial behaviors using the electrostatic interaction between positive chitosan and negative octenyl succinic anhydride (OSA) starch. The partial polysaccharide complex of OSA starch/chitosan was used to stabilize HIPE, which was able to adsorb at the oil droplet interface and prevent the coalescence of oil droplets. The wettability of OSA starch was enhanced with the addition of positively charged chitosan, leading to the formation of partial complexes. The impact of pH and concentration of chitosan on the droplet size, surface charge, and interface behavior were investigated, and the formation of the polysaccharide complex was further confirmed by atomic force microscopy. The presence of the OSA starch/chitosan complex facilitated the formation of stable HIPE with a gel-like structure and satisfactory centrifugal and oxidative stability. These results are useful to provide information for fabricating polysaccharide-based HIPE delivery systems, which may help expand their application in the food industry.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2019
·Vol. 322
·期 2
·553-559
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IF 1.186
Wu Peng,Wang Yun,Li Yang,Hu Xuewen,Xiu Taoyuan,Yuan Dingzhong,Liu Yan,Wu Zhenyu,Liu Zhirong
In order to reduce the potential toxicity to the environment after treatment of radioactive waste water, an eco-friendly graphene oxide nanoribbons/chitosan (GONRs-CTS) composite was prepared and utilized for adsorption of Th(IV) from aqueous solution. The GONRs-CTS adsorbent was characterized by XRD, FTIR and SEM, indicating that GONRs-CTS contains a large amount of oxygen-containing groups and chitosan was successfully attached to the GONRs surface. The Th(IV) adsorption on GONRs-CTS was endothermic and spontaneous, with the maximum single layer adsorption capacity was 140.6 mg g −1 at pH = 3.0, in the contact time of 12 h. The adsorption process was consistent with pseudo-second-order kinetics and the Langmuir isotherm model.
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CARBOHYDRATE POLYMERS
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2019
·
IF 6.044
Jiaoyan Liu,Bin Yang,Minhui Li,Jing Li,Ying Wan
Thiolated chitosan (CS-NAC) was synthesized and the selected CS-NAC was used together with silk fibroin (SF) to produce dual network CS-NAC/SF hydrogels. The CS-NAC/SF solutions with formulated compositions were able to form hydrogels at physiological temperature and pH. Rheological measurements showed that elastic modulus of some CS-NAC/SF gels could reach around 3 kPa or higher and was much higher than their respective viscous modulus, indicating that they behaved like strong gels. Deformation measurements verified that CS-NAC/SF gels had well-defined elasticity. The optimized CS-NAC/SF gels exhibited jointly enhanced properties in terms of strength, stiffness and elasticity when compared to the gels resulted from either CS-NAC or SF. Examinations of dry CS-NAC/SF gels revealed that they were highly porous with well-interconnected pore features. Cell culture demonstrated that CS-NAC/SF gels supported the growth of chondrocytes while effectively maintaining their phenotype. Results suggest that these dual network gels have promising potential in cartilage repair.
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