JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2023
·
IF 4.5
Haifeng Yao,Yahui Zhang,Yongping Dong,Mingfu Ye
Graphdiyne (GDY) is considered as another promising carbon material in biosensing field. However, the application of GDY in ECL sensing is in its infancy stage, and different roles of GDY are urgent to be discovered. In this work, strong anodic Ru(bpy) 3 2+ electrochemiluminescence (ECL) was obtained at a cucurbit[8]uril (Q[8]) modified electrode. Although GDY exhibited electrocatalytic effect on the oxidation of Ru(bpy) 3 2+ , an apparent inhibiting effect of GDY on the ECL signal was observed due to the energy transfer. An “on-off-on” mode ECL sensor was fabricated to detect pancuronium (PMD) based on the competitive host–guest interaction between ferrocene (Fc), PMD and Q[8]. Fc modified single-stranded DNA was immobilized onto the surface of GDY, which could be attached onto the electrode through the interaction between Fc and Q[8]. The quenching effect of GDY could apparently decrease ECL signal. PMD exhibited stronger combining ability with Q[8] than Fc, and could replace Fc from the cavity of Q[8], leading to the recovery of ECL signal. The variation of ECL intensity changed linearly with the PMD concentration in the range of 10 nM to 50 μM with a detection limit of 5 nM (3σ). The proposed sensor has high sensitivity, outstanding specificity and accuracy, indicating that GDY has promising potential application in ECL sensing field based on its inhibiting effect.
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高影响因子
CHEMICAL ENGINEERING RESEARCH & DESIGN
·
2023
·
IF 3.9
Xiangyang Liu,Longhui Fang,Jin Wang,Sihan Huang,An Li,Hui Liu,Zhuoyang Lu,Jiangang Long,Maogang He
R410A is a high GWP (2088) refrigerant blend soon to be eliminated, consisting of equal mass of difluoromethane (R32) and pentafluoroethane (R125). R32 is a good additive to the next generation refrigerant hydrofluoroolefin due to low GWP (675) and superior thermodynamic properties. But the separation of R32 and R125 by conventional distillation is a challenge because of their near boiling points. In this study, innovative membranes combining metal-organic framework (MOF) and ionic liquid (IL) are applied to the recovery of valuable R32 from R410A and demonstrate excellent R32/R125 separation performance. [C 2 mim][BF 4 ] was embedded into the nanocages of ZIF-8 through a impregnation strategy to prepare ZIF-8@[C 2 mim][BF 4 ]/Pebax mixed-matrix membranes (MMMs). Characterization results confirmed that IL was successfully added to the nanocages of ZIF-8. ZIF-8@[C 2 mim][BF 4 ]/Pebax MMMs with 10 wt% loading exhibits the best separation performance, increasing R32 permeability and R32/R125 selectivity by 177% and 150% compared to neat Pebax membrane. The ZIF-8 @ [C 2 mim][BF 4 ] material by impregnation has excellent performance in regulating the effective cage size of MOF, providing new strategies for designing more accurate and efficient MMMs.
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SURFACE & COATINGS TECHNOLOGY
·
2023
·
IF 5.4
Yi Huang,Chenyang Zhao,Yue Li,Chen Wang,Wenlin Yuan,Tao Shen,Jie Liu,Di Cheng,Chunchun Wu,Qianhong Shen,Hongliang Ding,Siyuan Chen,Hui Yang
Integration of both passive and active corrosion-protecting mechanisms is an effective method for endowing sol-gel derived coatings with long-term anticorrosion performance. To provide “smart” functionality for sol-gel coating, a novel self-healing nanocontainer is fabricated via the in-situ growth of 1H-benzotriazole-inbuilt zeolitic imidazolate framework (BTA-ZIF-8) on hydroxylated hexagonal boron nitride nanosheets (BN-OH), which exhibits efficient pH-dependent inhibitor release behavior at both acidic and alkaline media. Electrochemical measurements reveal that sol-gel coating containing the BTA-ZIF-8@BN-OH nanocontainers exhibits superior anticorrosion performance and long-term corrosion protective capability, with |Z| 0.01Hz increased by nearly three orders of magnitude (∼2 × 10 8 Ω·cm 2 ) compared to that of pure sol-gel coating after 28 days of saline solution immersion. In addition, the EIS measurements on sol-gel coating surfaces with artificial scratches show increased impedance values after prolonged immersion in saline solution, indicative of effective active inhibiting effect. This phenomenon is the result of the synergistic effect of both passive and active corrosion protection . The active protection (inhibiting effect) is provided by the on-demand release of inbuilt BTA inhibitor from ZIF-8 frameworks, whereas the passive protection (barrier performance) is achieved through the “labyrinth effect” of BN-OH nanosheets as well as the improved interfacial compatibility of nanocontainers with surrounding sol-gel matrix by surface hydroxylation of h-BN nanosheets. This nanocontainer design offers a facile strategy for fabricating self-healing sol-gel coatings with the exceptional anticorrosion properties.
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PROGRESS IN ORGANIC COATINGS
·
2023
·
IF 6.6
Lei Ling,Shu Cai,You Zuo,Tengfei Meng,Hao Tian,Xiaogang Bao,Guohua Xu
Recently, superhydrophobic coating modified magnesium alloys are extensively utilized for anti-corrosion, anti-fouling and anti-bioadhesion fields due to their unique surface characteristics. However, lack of antibacterial and osteogenic properties have restricted the development of medical magnesium alloys for clinical implantation. Here, a facile superhydrophobic wettability transformation strategy is proposed to impart medical magnesium alloys with outstanding corrosion resistance , protection against bacterial infection and promotion of osteogenesis process. The copper (Cu 2+ )-doped zeolitic imidazolate frameworks-8 (ZIF-8) coatings were synthesized upon the surface of HA-modified Mg alloy via solvothermal method and then followed hydrophobic treatment in a mixed ethanol solution of dodecyl mercaptan (DDM) and myristic acid (MA) to obtain superhydrophobic properties. This particular superhydrophobic coating can be irradiated by visible light to make ligand-to-metal charge transfer produce photoelectrons and be captured upon the Cu@ZIF-8 coating surfaces as paramagnetic Zn 2+ sites, and then generated reactive oxygen species which can scavenge off the reductive dodecyl mercaptan, thus converting to hydrophilic. This wettability transition allows for the regulation of implant surface properties according to the functional requirements of the implant at different clinical stages. Furthermore, the composite coatings modified Mg alloy after wettability transformation from superhydrophobic to hydrophilic can significantly kill pathogenic bacteria and promote osteoblast attaching behavior.
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Journal of Materials Chemistry B
·
2023
·Vol. 11
·期 34
·8216-8227
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IF 7
Zhipeng Yuan,Jing Zhang,Xinfu Zhao,Sijia Liu,Shimo Yu,Xiaochan Liu,Xinen Zhang,Xibin Yi
Rapid and safe disinfection and exudate management are two major challenges in infected wound care. Therefore, in this work, we developed a novel wound dressing via encapsulating ZIF-8-derived carbon nanoparticles in a hydrophilic nanofiber sponge to address severe wound infection and heavy exudate problems. The dressing can effectively kill bacteria through chemo-photothermal synergistic therapy. Meanwhile, the hydrophilic nanofiber sponge can quickly absorb wound exudate around the wound and accelerate the evaporation rate of liquid through the photothermal effect and its own structure; therefore, it is possible to remove excess liquid and regulate its wetness. In this way, it prevents the problem of wound overhydration often caused by hydrophilic dressings. In our experiment, the dressing showed good antibacterial performance and biocompatibility in vitro and could effectively control wound infection, absorb wound exudate and promote skin wound healing in vivo. Its good therapeutic effect is not only due to effective infection control and wound exudate management, but also because the structure of nanofibers similar to an extracellular matrix provides basic physical support and structural signals conducive to skin tissue regeneration.
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PubMed
高影响因子
POLYMER COMPOSITES
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2023
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IF 5.2
Xiaoqian Li,Xiaohua Jia,Jin Yang,Yong Li,Hongliang Lin,Haojie Song
Existing research on interfacial interactions of recyclable carbon fiber reinforced poly(hexahydrotriazine) (PHT) composites has mainly focused on the study of reinforcing fibers, ignoring the wide range of applications of matrix in advanced friction materials. Herein, polyhedral ZIF-8 was grown in-situ on the GO surface (named as ZIF-8@GO) to improve the load-bearing capacity of GO nanosheets. The ZIF-8@GO with zinc ions and imidazole ions were embedded as interlaminar reinforcement into matrix to construct a non-covalent cation-π interaction with indole-based PHT (In-PHT) matrix, which significantly enhanced the toughness and tensile strength (reached 215.5 MPa) of composites. With the incorporation of armor-shaped ZIF-8@GO reinforcement, compared with the composite without ZIF-8@GO, the wear track width was significantly decreased by 50%. Moreover, the worn surface lubricated by this composite exhibited efficient self-healing property due to the introduction of the polyethylene wax (PEW), and the healed average friction coefficient showed slight changes. Extensive analyses verify that the ZIF-8@GO structure and cation-π interactions across multiscale interfaces can enhance both mechanical strength and wear resistance of recyclable carbon fiber reinforced In-PHT composites (In-PHT-CFRPs). Highlights ZIF-8@GO was embedded as interlayer reinforcement to improve wear resistance. Cation-π interaction across interface enhances interface carrying capacity. Due to strong cation-π bonding, IPEZGC exhibits outstanding tensile strength. PEW was embedded as healing agent to obtain self-healing property.
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JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 25
·10441-10456
·
IF 4.5
Xia Qing,Shen Jia,Li Xiang
Clinical chemotherapy is hindered due to its poor therapeutic impact and severe adverse effects. To work within the challenges of poor circulation stability and unexpected drug leakage in blood circulation, we developed pH-responsive nanoplatforms based on silk sericin-coated zeolitic imidazolate framework-8 to deliver the chemotherapeutic cabazitaxel (designated ZIF-8@CTX@SS, ZCS). ZIF-8's improved stability and biocompatibility can be attributed to the shielding of the naturally occurring and non-toxic sericin protein. ZIF-8's coordinating action triggers the release of CTX drugs in a low pH environment, like that observed in the microenvironment of tumor cells. Newly fabricated nanoparticles showed improved anticancer potential in liver cancer cells (HepG2 and Bel7402). According to the fluorescence-based mechanism of anticancer activity, ZIF-8@CTX@SS enhanced reactive oxygen species (ROS) levels and caused DNA fragmentation, which resulted in apoptosis. The study's findings indicate that ZIF-8@CTX@SS is a potentially biocompatible nanomaterial for drug delivery systems for treating liver cancer applications. Taken together with all the advantages in this investigation, this silk sericin-based nanoframework represents a promising approach for developing stimuli-responsive by employing natural polymers to enhance the chemotherapy effects.
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Analytical Methods
·
2023
·Vol. 15
·期 18
·2199-2209
·
IF 3.1
Kuiguo Han,Liang Chen,Wen Zhang,Yanqun Tong,Jiyong Shi,Xiaoyu Su,Xiaobo Zou
This work describes the synergistic application of semi-complementary aptamer pairs and signals on–off ratio strategies on glassy carbon electrodes (GCE) for detecting lead ions (Pb2+) in fish. Gold nanoparticles (AuPNs) as the electrode substrate can provide added binding sites for the aptamers and improve the conductivity of the electrodes. Pb2+ aptamers containing ferrocene (Fc) molecules act as molecular recognizers in the sensing system. In the presence of target ions, Fc signals are affected by conformational changes of the aptamer. The “Ag nanowires@zeolitic imidazolate framework-8 with methylene blue (AgNWs@ZIF-8/MB)” can be semi-complementary to the Pb2+ aptamer after binding to single-stranded DNA (S1). However, S1/AgNWs@ZIF-8/MB self-assembled with Pb2+ aptamer (Apt) by hybridization incubation was quickly replaced by Pb2+ competitively, resulting in the loss of methylene blue (MB) signaling molecules. Hence, the internal reference signal (MB) and conformation change signal (Fc) comprise the ratio sensing system well. Morphology, spectroscopy, and electrochemistry methods have validated the modification and sensing behaviors. The used Apt has made considerable progress in analytical performance. In interference studies and stability checks, the ratio measurement signal IFc/IMB is a more reliable signal than the single signal readout. Following a log-linear relationship, this sensor provides a wide linear range. Furthermore, the proposed sensor can be used to determine Pb2+ in fish samples, and the results agree with those obtained using ICP-MS and recovery tests.
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高影响因子
RSC Advances
·
2018
·Vol. 8
·期 45
·25351-25360
·
IF 2.936
Xiaodong Huang,Yanan Liu,Guangyang Liu,Lingyun Li,Xiaomin Xu,Shuning Zheng,Donghui Xu,Haixiang Gao
A novel magnetic zinc-based zeolitic imidazolate framework (MMP/ZIF-8) has been prepared using a magnetic multiwalled carbon nanotube@polydopamine nanocomposite as the magnetic core and support. It was then used as an adsorbent for magnetic solid-phase extraction of triazole fungicides from environmental water samples. Successful synthesis of MMP/ZIF-8 was confirmed by material characterization, and the results showed that the synthetic composite has a high Brunauer–Emmett–Teller surface area (141.56 m2 g−1), large total pore volume (0.636 mL g−1), and high superparamagnetism with a saturation magnetization of 44.1 emu g−1. To evaluate the extraction performance of MMP/ZIF-8, the main parameters that affect the extraction efficiency were optimized. Under the optimal conditions, the developed method shows good linearity (R2 ≥ 0.9915) in the concentration range 1–400 μg L−1. Low limits of detection (0.08–0.27 μg L−1, signal/noise = 3 : 1) and good precision (intraday relative standard deviation ≤ 7.73%, interday relative standard deviation ≤ 9.65%) are also achieved. The developed method was applied for analysis of triazole fungicides in environmental water samples.
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高影响因子
ANALYST
·
2018
·Vol. 143
·期 15
·3619-3627
·
IF 3.864
Qiuyue Zhao,Qi Zhang,Yuena Sun,Yuexian Liu,Haijun Lu,Xinyu Fan,Haiyang Wang,Yufan Zhang,Huan Wang
A controllable flower-like Pt-graphene oxide (PtNF-GO) architecture was synthesized through layer-by-layer electrostatic self-assembly. Hexadecyltrimethylammonium chloride (CTAC) micelles were employed as the template and Pt nanoflowers with different sizes were selectively synthesized by controlling the dissolved K2PtCl4 precursor and CTAC amounts in the reaction system. The prepared PtNF-GO was applied for DNA damage biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) biosensing research. With the distinctive flower-like morphology of PtNFs and high electrical conductivity of GO, the PtNF-GO architecture shows excellent electrochemical biosensing performance towards the oxidation of 8-OHdG. A very low detection limit of 0.025 nM is obtained. Moreover, the fabricated PtNF-GO was used for the detection of 8-OHdG generated from the damaged DNA sample, which can be used to evaluate and confirm the mechanism of DNA damage, and it is of great importance in gene diagnosis, clinical and life sciences.
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PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2018
·Vol. 28
·期 35
·1802830
·
IF 13.325
Huiyuan Zhang,Qian Li,Ruiling Liu,Xinke Zhang,Zhonghao Li,Yuxia Luan
Zeolitic imidazolate framework-8 (ZIF-8) is an attractive metal organic framework (MOF) in drug delivery. Strong interaction between drugs and ZIF-8 is essential for high drug loadings through in situ construction of MOFs. However, only limited drugs with unique functional groups ( COOH, SO 3 H, et al.) can interact with ZIF-8 and be encapsulated satisfactorily so far. Drugs without these functional groups are difficult to be loaded due to the lack of strong interaction. Herein a versatile prodrug strategy is proposed to solve the problems encountered by MOFs. Cytarabine (Ara) is chosen as a model drug since it cannot be loaded in ZIF-8 satisfactorily by itself. New indocyanine green (IR820) is utilized to bond with Ara for the formation of prodrug (Ara-IR820) and endows the prodrug with fluorescence imaging-guided chemo-photothermal therapy, in which sulfonic groups strengthen the interaction between prodrug and ZIF-8. This prodrug loaded ZIF-8 is further functionalized with hyaluronic acid (HA) to result in active-targeting HA/Ara-IR820@ZIF-8 nanoparticles. The in vitro and in vivo results demonstrate its excellent visual cancer therapy with tumor-targeted and pH-responsive release behavior. This design offers a new concept to solve the drug loading problem of MOFs, exhibiting a flexible strategy to expand the biomedical applications of MOFs.
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DYES AND PIGMENTS
·
2012
·
IF 3.126
Lijuan Feng,Chunyu Wang,Zhonglin Ma,Changli Lü
8-Hydroxyquinolines (HQs) functionalized ZnS nanoparticles (NPs) with an amine-capping layer (ZnS–NH 2 –Q NPs) were prepared by a ligand-exchange process. FT-IR, XRD , NMR, TEM and fluorescence spectrometer were used to characterize the novel ZnS–NH 2 –Q NPs. Upon the addition of 2,4,6-trinitrotoluene (TNT), the amino groups on the surface of ZnS–NH 2 –Q NPs can bind TNT molecule from solution by forming Meisenheimer complex. This complex absorbs the green part of visible light, and strongly suppresses the fluorescence emission of the ZnS–NH 2 –Q NPs through Fluorescence Resonance Energy Transfer (FRET). The observed linear fluorescence intensity response for TNT in the range of 0–1.89 μM allows the quantitative detection TNT, with a detection limit down to 10 nM.
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危险品化学品经营许可证（带存储）