PHYSICA SCRIPTA
·
2025
·Vol. 100
·期 10
·105607
·
IF 2.6
Xiaolong Song,Yafang Pan,Shi Wang,Peng Wang,Mingli Wang
Compared with single-metal materials, bimetallic materials exhibit superior oxidation resistance and stability. The Surface-enhanced Raman Scattering (SERS) performance can be effectively modulated by adjusting the concentration of the precursors. Herein, Fe3O4@EDTA@Ag-Cu NPs were successfully synthesized, the SERS performance of the substrate was significantly enhanced by modulating the concentration of the silver and copper precursors. The results indicated that the SERS sample prepared by mixing the dispersion of Fe3O4@EDTA@Ag-Cu NPs with Rhodamine 6G(R6G) solution at a 1:2 volume ratio, achieved a detection concentration as low as (1.0 ± 0.2) × 10−10 M for R6G. Furthermore, the substrate demonstrated high sensitivity, uniformity, temporal stability, reproducibility, and the capability for the rapid detection of benzimidazole in strongly alkaline conditions.
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Materials Today Bio
·
2025
·
IF 10.2
Han Shi,Zhiqiang Xie,Junrong Zhang,Fengchun Lu,Haoteng Luo,Pengfei Guo,Meichen Jiang,Zongqi Weng,Xin Luo,Bing Chen,Heguang Huang,Tianhong Teng
Reprogramming of branched-chain amino acid (BCAA) metabolism is a key mechanism promoting pancreatic cancer progression. While gabapentin (Gp) can inhibit BCAA catabolism by targeting branched-chain amino acid aminotransferase 1 (BCAT1), its efficacy is limited by inefficient delivery and compensatory mitochondrial metabolism. To address this, we developed a novel copper ionophore-functionalized mesoporous silica nanoplatform (XQ/Gp@CMSNs) for synergistic cuproptosis and tumor-starvation therapy. The designed nanoparticles exhibit excellent pancreatic cancer-targeting capability via XQ-2d aptamer modification and acid-responsive drug release within the tumor microenvironment. Upon internalization, XQ/Gp@CMSNs simultaneously induce mitochondrial copper overload and disrupt BCAA metabolism, leading to dihydrolipoamide S-acetyltransferase (DLAT) oligomerization, ferredoxin 1 (FDX1) downregulation, and tricarboxylic acid (TCA) cycle suppression. Both in vitro and in vivo studies demonstrated potent antitumor efficacy with minimal systemic toxicity. Metabolomic analyses further confirmed synergistic BCAA metabolic inhibition and copper-induced mitochondrial dysfunction. This work presents a promising metabolic intervention strategy for pancreatic cancer through targeted nanomedicine.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Xiaorui Zhang,Ziheng Yang,Zikang Zeng,Laiqing Zhang,Wenxuan Wang,Xiaohe Jiang,Xingwei Ge,Yujun Liang,Chuang Han
Nitroarene reduction, a critical route for synthesizing the corresponding amines. However, conventional thermocatalytic typically involves harsh reaction conditions (high temperature, pressurized hydrogen, and anaerobic atmospheres) and relies on precious metals or extended reaction times. Herein, we have achieved photocatalytic CO 2 emission-free hydrogenation of nitroarenes at ambient conditions by introducing isolated Cu single atoms (Cu SAs) synergize with self-adaptive S vacancies (Svs) in CdS. In the presence of hydrazine servicing as an efficient hole sacrificial agent with harmless oxidation products, current design could circumvent the need for precious metals, high temperatures, strong radiation, vacuum environments, or H 2 gas. It is demonstrated that the isolated Cu sites and S vacancies act as hole-trapping centers and electron-enriched regions, respectively, which facilitate the effective separation and prolong the lifetime of charge carriers in the region, and achieve 97 % conversion of 4-NA within 8 min under mild conditions, outperforming many previously reported photocatalytic systems. In addition, the optimal Cu-CdS-5 demonstrates remarkable recyclability along with wide substrate scope. This research is expected to provide a new insight into the construction of facile and environmentally friendly photocatalytic hydrogenation reaction system.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Guanshu Li,Yingmin Jin,Yumeng Li,Wenhao Cui,Haojie An,Ruxue Li,Chundong Li
Designing efficient and stable photocathodes remains a critical challenge for advancing high-performance photocatalytic fuel cell (PFC) systems toward simultaneous pollutant removal and energy conversion. Herein, we report a novel Cu-Cu 2 O/carbon nanofibers (CNFs) photocathode, synthesized via an electrospinning-calcination method, in which the Cu-Cu 2 O heterostructures are uniformly anchored onto conductive CNFs rich in oxygen vacancies. As a proof of concept, a dual-photoelectrode PFC system was constructed to evaluate the performance of the Cu-Cu 2 O/CNFs photocathode. The PFC achieved an 83 % degradation rate for Rhodamine B (RhB) in 2 h and a maximum power density (P max ) of 42.99 μW/cm 2 , markedly outperforming the commercial Cu 2 O-based cathode PFC system. Moreover, the PFC system assembled with the Cu-Cu 2 O/CNFs photocathode exhibited consistent degradation efficiency and power output over multiple cycles, demonstrating that the cathode plays a crucial role in ensuring the long-term stability of the system. Experimental and theoretical calculation results confirm that the unique local electronic structure and coordination environment at the Cu/Cu 2 O interface promote O 2 adsorption and lower the energy barrier for the oxygen reduction reaction (ORR). This work demonstrates a rational strategy for designing high-efficiency Cu-based photocathodes and offers new insights into optimizing photoelectrocatalytic materials for environmental and energy applications.
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ACS Catalysis
·
2024
·
IF 11.3
Chong Qi,Yifu Bi,Yaolin Wang,Hong Yu,Yuanyu Tian,Peijie Zong,Qinhua Zhang,Haonan Zhang,Mingqing Wang,Tao Xing,Mingbo Wu,Xin Tu,Wenting Wu
Nonthermal plasma (NTP) offers the potential for converting CH4 with CO2 into liquid products under mild conditions, but controlling liquid selectivity and manipulating intermediate species remain significant challenges. Here, we demonstrate the effectiveness of the Cu/UiO-66-NH2 catalyst in promising the conversion of CH4 and CO2 into oxygenates within a dielectric barrier discharge NTP reactor under ambient conditions. The 10% Cu/UiO-66-NH2 catalyst achieved an impressive 53.4% overall liquid selectivity, with C2+ oxygenates accounting for ∼60.8% of the total liquid products. In situ plasma-coupled Fourier-transform infrared spectroscopy (FTIR) suggests that Cu facilitates the cleavage of surface adsorbed COOH species (*COOH), generating *CO and enabling its migration to the surface of Cu particles. This surface-bound *CO then undergoes C–C coupling and hydrogenation, leading to ethanol production. Further analysis using CO diffuse reflection FTIR and 1H nuclear magnetic resonance spectroscopy indicates that in situ generated surface *CO is more effective than gas-phase CO (g) in promoting C–C coupling and C2+ liquid formation. This work provides valuable mechanistic insights into C–C coupling and C2+ liquid production during plasma-catalytic CO2 oxidation of CH4 under ambient conditions. These findings hold broader implications for the rational design of more efficient catalysts for this reaction, paving the way for advancements in sustainable fuel and chemical production.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Wenbin Tang,Jin Shen,Zhongjie Shen,Jiawei Wang,Haifeng Liu
The four-step Cu–Cl thermochemical hydrogen production cycle can effectively convert heat energy into hydrogen energy, and the thermolysis reaction is the key stage for connecting the upstream and downstream reactions. This study focused on the influence of different upstream hydrolysates (Cu2OCl2 or CuO) on thermolysis and the different reaction mechanisms. The micromorphological changes during the reaction process, the specific information on the precipitated gases, and the effect of temperature and reaction time on the main and byproducts were analyzed. The results showed that the maximum CuCl yields of 84.58 and 82.26% were obtained from the thermolysis of Cu2OCl2 and CuCl2–CuO equimolar mixtures. During the reaction, both reaction feedstocks shrink and then melt and start to precipitate O2 at 430 and 415 °C, respectively. For the thermolysis of CuCl2–CuO mixtures, an excess of CuCl2 contributes to the main reaction. Finally, the complex reaction mechanism of thermolysis and product regulation was revealed.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Qiulan Li,Jiahe Dai,Yaling Yang,Linqian Hou,Hong Li
In this study, an “off” signal chemiluminescence (CL) sensor was designed for the detection of glyphosate (Gly) based on Cu-CDs/ABEI@Ag as CL enhancers. Copper-doped carbon dots (Cu-CDs) was synthesized through a sample microwave digestion approach, and AgNO 3 was reduced to silver nanoparticles (AgNPs) utilizing N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and prepared Cu-CDs as mild reducing agents. The Cu-CDs and AgNPs demonstrated peroxidase (POD)-like properties, facilitating the breakdown of H 2 O 2 into reactive oxygen species (ROS) such as ∙OH, ∙O 2 − , and 1 O 2 to generate CL signal. By integrating ABEI into the catalyst system, the CL reagent became concentrated within the catalyst structure, minimizing the spatial separation between the catalyst and ABEI, thus amplifying the CL response. Notably, Gly can inhibit POD-like activity by interaction between Cu-CDs/ABEI@Ag and Gly, thus decrease the CL intensities produced from oxidation of ABEI. Based on this highly sensitive “off” response in CL, a CL nano-sensor was developed for Gly detection, achieving a detection limit of 3.87 μg/L. Furthermore, satisfactory spiked recovery rates (95.86–111.13%) were obtained in coffee samples, highlighting the sensor's promising applicability for on-site Gly monitoring.
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APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Mingnv Guo,Yulin Chen,Jiahao Liu,Jiaqi Qiu,Wenjing Wang,Zhongqing Yang
This study employs a Cu–Ni co–doping strategy to construct a Bi 2 MoO 6 photothermal synergistic catalyst, achieving highly efficient conversion of CO 2 reduction. Under ultraviolet–visible (UV–Vis) xenon lamp irradiation and 200 °C external heating conditions, the optimal sample (3Cu-6Ni-Bi 2 MoO 6 ) exhibited CO and CH 4 yields of 293.16 μmol·g −1 and 98.43 μmol·g −1 respectively, within 4 h, representing 6.8-fold and 5.3-fold increases compared to the undoped sample. The significant enhancement in CO 2 conversion activity can be attributed to the following factors: (1) Co-doping with Cu 2+ and Ni 2+ induces lattice distortion and oxygen vacancy formation, generating defect energy levels near the valence band edge. This reduces the bandgap to 2.1 eV, thereby broadening the visible light absorption range; (2) Oxygen vacancy defects provide highly efficient CO 2 adsorption and activation sites; (3) Doping with Cu and Ni enhances the separation and transport efficiency of photogenerated carriers.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 13.2
Weixin Zhang,Xin He,Ting Zhang,Haomiao Li,Shuai Yan,Xianbo Zhou,Yewei Guo,Min Zhou,Wei Wang,Kai Jiang,Kangli Wang
Liquid metal batteries (LMBs) are an attractive large-scale energy storage technology due to their ultra-long service life, high safety, and exceptionally low comprehensive cost. Te-based LMBs are regarded as one of the most promising directions for developing high-energy-density LMBs. However, their practical application is still hindered by low Coulombic efficiency and short cycle life, primarily due to the shuttle effect induced by the dissolution of reaction products. Herein, the strategy of employing transition metal (Cu) with strong polar interactions with lithium polytellurides as the alloying element to construct cathode is proposed. Benefiting from the strong adsorption and conversion-promoting capabilities of in-situ generated metal tellurides (CuTe and Cu 4 Te 3 ) towards lithium polytellurides, the shuttle effect is significantly suppressed. The designed Li||Te 7 Cu 3 LMBs deliver a stable cycling performance of over 848 cycles with a coulombic efficiency exceeding 97%, ultrahigh energy density (465 Wh kg −1 ) and outstanding rate performance (2.1C, >90% capacity retention). This study opens up new avenues for designing high-performance Te-based LMB cathodes.
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AICHE JOURNAL
·
2026
·
IF 4
Jie Li,Ying Liao,Ming Guo,Yue Pan,Yaqian Li,Xuechao Yang,Yulin Wang,Meiyu Zhang,Mengnan Ma,Xiaobo Chen,Yibin Liu,Hao Yan,Chaohe Yang
Direct dehydrogenation of alcohols to aldehydes is a pivotal transformation in fine chemical synthesis. However, conventional thermal processes often suffer from low efficiency and high energy consumption. Herein, we propose an emerging and sustainable strategy that employs CO 2 -assisted in situ hydrogen extraction to drive the dehydrogenation of alcohols under mild conditions. Specifically, CO 2 as a soft oxidant adsorbs and activates on the Cu–ZnO–Al 2 O 3 composite oxide catalyst surface, generating reactive species (COO*) that selectively abstract hydrogen from the α -C of the alcohol. Combined Langmuir-Hinshelwood kinetic analysis and density functional theory calculations reveal a higher formation rate of the aldehyde product and the lower activation barrier for the key C–H bond activation process under the CO 2 atmosphere. As a result, the CO 2 -assisted dehydrogenation markedly enhances reaction efficiency, achieving a 60.21% conversion of 2-ethylhexanal under a low temperature (240°C), which is nearly twice that observed under the pure N 2 atmosphere. This CO 2 -assisted dehydrogenation strategy in this work exhibits a cooperative catalytic pathway that not only enables efficient aldehyde production but also utilizes CO 2 as a chemical resource.
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Theranostics
·
2026
·Vol. 16
·期 1
·398
·
IF 13.3
Jian Xu,Susu Zhang,Yu Yang,Xingwei Wei,Yunteng Fang,Zhilin Wang,Linwen Lan,Jiayi Shen,Enqian Liu,Wuming Hu,Tingting Hu,Chaojie Yu,Ruizheng Liang,Lingchun Lyu
Rationale: Myocardial ischemia-reperfusion (MI/R) injury induces apoptosis, metabolic dysregulation, and ventricular remodeling through complex pathological mechanisms. Although nanozyme engineering has the potential for antioxidation, reoxygenation, and pro-vascularization, achieving responsive modulation of the pathological microenvironment remains significantly challenging. Methods: A layered double hydroxide (LDH)-based nanozyme (ZnSrMo-LDH/Cu) was synthesized via a low-temperature hydrothermal/isomorphic substitution method for MI/R treatment. The reactive oxygen species (ROS) scavenging ability and responsive ion release performance of ZnSrMo-LDH/Cu were evaluated through various spectroscopic characterization methods. The biosafety and therapeutic efficiency of ZnSrMo-LDH/Cu-BSA nanozymes were assessed by in vitro and in vivo experiments. Results: ZnSrMo-LDH/Cu demonstrated cascade superoxide dismutase (SOD) and catalase (CAT) activities, effectively overcoming acidic microenvironment limitations to maintain CAT activity rather than peroxidase (POD) activity while scavenging ROS to generate oxygen, with a ROS scavenging capacity 2.97 times that of Fe 3 O 4 . Moreover, the acid-triggered Sr 2+ release promoted vascular regeneration and synergistically improved the ischemic-hypoxic microenvironment. Consequently, after bovine serum albumin (BSA) modification, ZnSrMo-LDH/Cu-BSA demonstrated excellent cytoprotective effects, reducing the cardiomyocyte apoptosis rates to 9.4% ( in vitro ) and 20.7% ( in vivo ) of the levels in the MI/R group. In vivo studies further validated that ZnSrMo-LDH/Cu-BSA enhanced cardiac function and attenuated ventricular remodeling by inhibiting oxidative stress and promoting angiogenesis. Mechanistically, ZnSrMo-LDH/Cu-BSA provided a cardioprotective effect by inhibiting the TGF-β signaling pathway, thereby alleviating cell damage caused by MI/R. Conclusions: The pathologically responsive LDH-based nanozyme represents a promising avenue for MI/R treatment.
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MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION
·
2024
·Vol. 76
·期 2
·214-225
·
IF 1.6
Xuyan Guo,Zhuangzhuang Xiong,Guixiang Wang,Fuqiu Ma,Mingbo Ji,Ruizhi Wu
This study developed a green and efficient surface protection method for Cu–Ni alloys. A zinc dibenzyl dithiocarbamate film was prepared on the surface of electrodeposited Cu–Ni alloys using the self-assembly method to improve the material's corrosion resistance in seawater. The influence of zinc dibenzyl dithiocarbamate concentration and self-assembly time on the corrosion resistance of the self-assembled films was investigated through electrochemical testing. The findings revealed that at a zinc dibenzyl dithiocarbamate concentration of 10 mmol/L and a self-assembly time of 20 min, the self-assembled film exhibited the most robust corrosion resistance, achieving a maximum corrosion inhibition efficiency of 97.70%. The self-assembly and adsorption mechanism of zinc dibenzyl dithiocarbamate were explored using molecular dynamics simulations and adsorption isotherms. The protective effect of self-assembled films was visually observed through salt spray testing. Zinc dibenzyl dithiocarbamate self-assembled film technology has high application prospects in the field of marine anti-corrosion.
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