JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.3
Li Sun,Qing Guo,Fan Yang,Kexin Wei,Siyuan Sun,Hongchen Liu,Junpu An,Yang Sun,Yang Guo,Linjie Wang,Yongfeng Li
Rationally designing single-atom catalysts (SACs) with high atomic efficiency and excellent catalytic performance is effective for boosting sodium borohydride (NaBH 4 ) hydrolysis activity. Herein, a series of Pt single-atom catalysts supported on Co-based compounds (Pt/CoP-B, Pt/CoP, Pt/Co 3 O 4 -B) were successfully synthesized via wet impregnation method. Pt M /CoP-B (6.2 wt% Pt loading) exhibited optimal performance at 30 °C: a turnover frequency (TOF) of 1103.26 mol H2 min −1 mol −1 Pt , a hydrogen generation rate (HGR) of 10746 mL min −1 g −1 cat which corresponded to 1.46 times higher than Pt M /Co 3 O 4 -B and 1.33 times higher than Pt M /CoP, outperforming most reported noble metal-based catalysts. It also possessed a low activation energy of 31.05 kJ mol −1 and excellent cycling stability, retaining 95.15 % of initial activity after five consecutive cycles. XPS confirmed strong metal-support interaction between Pt single atoms and CoP-B, which inducing electron transfer from Pt to Co to form electron-deficient Pt and electron-rich Co. DFT calculations revealed that Pt/CoP-B imposes a much lower energy barrier for rate-determining B–H bond cleavage and more effectively promotes H 2 O adsorption. This work offers a new paradigm for creating complementary electronic sites via single-atom-support synergy, opening a novel avenue for advanced NaBH 4 hydrolysis catalysts.
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 13.2
Rui Hu,Da-Wen Sun,You Tian,Liang Xu,Libin Sun
As a new cryoprotectant, natural deep eutectic solvents (NADESs) have been shown to achieve efficient and safe cryoprotection through excellent thermodynamic characteristics and strong recrystallisation inhibition ability. To further discover the cryoprotection mechanism of NADESs, the transcriptomics of yeast cells cryopreserved by different NADESs were examined. Notably, the PG cryoprotected yeast cells showed the highest viability (Q4: 81.39%) and the earliest regrowth peak (~ 6 h), indicating superior recovery performance. Transcriptomic analysis suggests that NADESs significantly modulate yeast cryotolerance. Differentially expressed genes (DEGs) were predominantly enriched in carbohydrate, amino acid, and fatty acid metabolism. Specifically, key genes involved in glycolysis, such as PCK1 , FBA1 , and ENO1 , were significantly regulated. Furthermore, the up-regulation of osmotic pressure-related genes ( STL1 , FPS1 ) in GF-cryopreserved yeast is consistent with observed osmotic changes. This suggests that proline-containing NADESs may help modulate osmotic pressure, thereby mitigating osmotic damage. Overall, this study supports a more comprehensive understanding of the cryopreservation mechanisms of emerging NADESs. Importantly, while these results support a role for NADES-induced shifts in glycolysis and osmoadaptation, the causality will be further validated in future work using HOG1 Δ, STL1 Δ, and FPS1 Δ strains, as well as pharmacologic MAPK inhibition.
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WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
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2026
·Vol. 42
·期 2
·54
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IF 4.2
Lu Zewei,Lv Changhui,Chen Zhuoer,Zhu Zhiwei,Ma Xiaoqiang
Kluyveromyces marxianus is a fast-growing, food-grade yeast with broad substrate utilization, however, its limited expression tools hinder its synthetic biology applications. Here, we developed single- and dual-gene expression systems based on screened elements, including a promoter pENO and a bidirectional promoter pHTX. These systems enabled stable expression across multiple K. marxianus strains, with expression levels affected by genetic element combinations, carbon source, and culture time. Using the single-gene system with a short intergenic sequence (IGG) for bicistronic expression, the production of leghemoglobin from Vigna angularis (VaHB) reached 30.4 mg/L using galactose as carbon source. In contrast, the dual-gene system achieved 48.4 mg/L of VaHB with the co-expression of HEM1 , enhancing heme biosynthesis using glucose as a carbon source. Additionally, Simian Virus 40 (SV40) nuclear localization signals (NLS) directed fluorescent proteins to the nucleus, enabling subcellular targeting. This toolkit supports efficient and context-responsive gene expression in K. marxianus , facilitating its development as a versatile microbial chassis for industrial protein production and synthetic biology applications. Graphical
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ADVANCED MATERIALS
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2026
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IF 26.8
Xinyue Liang,Yuchen Song,Xianzhen Dong,Junwei Su,Yuanfang Huo,Junwei Yang,Zhiqiang Li,Hao Zhang,Mengdi Liu,Aixi Yu,Honglian Dai
Due to the complex regenerative microenvironment, peripheral nerve repair poses significant challenges in clinical treatment. Severe injuries can lead to dysregulated iron homeostasis, and excessive iron produces reactive oxygen species (ROS) through the Fenton reaction. The subsequent oxidative stress further leads to mitochondrial and endoplasmic reticulum (ER) stress, which impedes nerve regeneration. In addition, insufficient vascular remodeling also limits the repair of damaged nerves. Herein, a poly(citric acid) (PCA)-loaded gelatin-lipoic acid (Gel-LA) microgel hydrogel-filled oriented electrospun fiber conduit was developed, which guides axonal alignment by topographical cues, promotes cellular infiltration and nutrient transport through a microgel cascade pore structure, and regulates the regenerative microenvironment via the ferrous ion (Fe 2+ ) chelation effect of PCA. The results demonstrate that this conduit effectively reduces the levels of Fe 2+ at the injury site, thereby alleviating mitochondrial and ER stress while promoting energy metabolism, vascular reconstruction, and nerve regeneration. This study highlights the potential of PCA in modulating the microenvironment of nerve injuries and provides new insights for developing tissue-engineered scaffolds.
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ACTA MATERIALIA
·
2026
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IF 9.3
Ka Wang,Qirui Wei,Ruilin Guan,Zhigang Zhang,Jiawei Zhang,Hengdong Ren,Wenqing Wei,Yuxiang Yan,Haizeng Song,Jingyi Han,Peng Zhan,Xianghong Niu,Shancheng Yan,Xinglong Wu
High-efficiency and low-cost oxygen evolution reaction (OER) catalysts are essential for advancing water electrolysis technologies. Transition metal thiophosphates (TMPSs) have garnered considerable interest in the OER field due to their ability to modulate the electronic states of active atoms through surface defect engineering. In this study, monolayer theoretical calculations reveal that the interaction between adjacent single-double sulfur vacancies (S-DSVs) significantly alters the electronic structure of phosphorus atoms, thereby tuning the binding strength with reaction intermediates and effectively lowering the energy barrier of the rate-determining step. As a result, S-DSVs outperform isolated single sulfur vacancies (SSVs) and double sulfur vacancies (DSVs). Single-layer FeNiP 2 S 6-x (SL-FeNiP 2 S 6-x ) catalysts with uniformly distributed S-DSVs were successfully synthesized via a mild and selective etching process using B(OH) 3 . Electrochemical measurements demonstrate that SL-FeNiP 2 S 6-x with an optimized S-DSV concentration delivers excellent OER performance, achieving a low overpotential of 171 mV at 10 mA cm -2 and a Tafel slope of 38 mV dec ‑1 in 1 M KOH—surpassing most reported iron/nickel-based OER catalysts. This work introduces a novel strategy for enhancing electrocatalytic activity by precisely controlling the position and distribution of sulfur vacancies through controllable etching.
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LWT-FOOD SCIENCE AND TECHNOLOGY
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2026
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IF 6.6
Zhou Huang,Ming Zhou,Baijun Ma,Hao Luo,Yucheng Jiao,Shi Chen
To overcome the challenges of volatile active agents and the limited functionality of biopolymer-based packaging, a novel synergistic strategy was devised by constructing a biomimetic “organelle-cytoplasm-cell wall” system within a chitosan/sodium alginate (CS/SA) matrix. This was achieved by simultaneously incorporating citric acid as a covalent crosslinker and porous starch (PS) pre-loaded with thymol (THY) as a sustained-release organelle. The synergistic interplay between the robust cross-linked network and the PS-THY capsules endowed the composite film (CS-c-SA/PS-THY) with exceptional comprehensive properties: a 42.23% enhancement in tensile strength, an order-of-magnitude reduction in water vapor permeability (7.11 g/(m 2 ·24 h)), and a 23 °C increase in thermal decomposition temperature. Crucially, the film achieved sustained and controlled THY release that obeyed Fickian diffusion, which underpinned its potent, long-lasting antioxidant (75.82% DPPH scavenging) and antibacterial (inhibition zones >18 mm) efficacy. In practical pork preservation, the CS-c-SA/PS-THY significantly outperformed the control and the CS-c-SA/THY, effectively inhibiting microbial growth and quality deterioration to extend the shelf life by at least 4 days. This work provides a scalable and fundamental strategy for developing high-performance, sustainable active packaging.
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Nano-Micro Letters
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2026
·Vol. 18
·期 1
·127
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IF 36.3
Wei Xiyan,Guan Jinpeng,Mu Yongbiao,Zou Yuhan,Wei Xianbin,Yang Lin,Man Quanyan,Yang Chao,Zang Limin,Sun Jingyu,Zeng Lin
Aqueous zinc-ion batteries (AZIBs) hold great promise for next-generation energy storage but face challenges such as Zn dendrite growth, side reactions, and limited performance at low temperatures. Here, we propose an electrolyte design strategy that reconstructs the hydrogen-bond network through the synergistic effect of glycerol (GL) and methylsulfonamide (MSA), enabling the formation of a (100)-oriented Zn anode. This design significantly broadens the operating current and temperature windows of AZIBs. As a result, Zn||Zn symmetric cells exhibit remarkable cycling stability, achieving 4,000 h at 1 mA cm −2 and 600 h at 40 mA cm −2 (both at 1 mAh cm −2 capacity); even at −20 °C, Zn||Zn symmetric cells deliver ultra-stable cycling for over 5,400 h. Furthermore, Zn||VO 2 full cells retain 77.3% of their capacity after 2,000 cycles at 30 °C with a current density of 0.5 A g −1 and 85.4% capacity retention after 2,000 cycles at −20 °C and 0.25 A g −1 . These results demonstrate a robust pathway for enhancing the practicality and low-temperature adaptability of AZIBs.
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JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 9
Youran Xu,Rukang Tian,Hao Zhang,Xiaowen Wu,Yunkun Wang
The transition to renewable energy and the pursuit of carbon neutrality have heightened the demand for lithium extraction from salt lake brines to ensure a sufficient lithium supply. Nanofiltration (NF) membranes offer an efficient method for solute sieving; however, achieving highly selective Mg 2+ /Li + separation remains challenging due to their similar hydration radii. This study introduces a synergistic modification strategy to adjust the surface physicochemical properties of NF membranes through incorporation of a sodium alginate interlayer and post-treatment with piperazine. The resulting modifications improved Mg 2+ selectivity by optimizing steric and Donnan exclusion mechanisms, achieved through a refined pore size distribution and reduced surface negative potential. Consequently, the modified membrane exhibited an outstanding Mg/Li selectivity factor (>100), with Mg 2+ rejection efficiency exceeding 98%. The membrane also demonstrated stable performance under mixed feed conditions with high total dissolved solids (TDS, 2000 ppm) and low Li + concentration (100 MgCl 2 /LiCl mass ratio). This study provides a facile and effective approach to enhance multiple exclusion mechanisms for Mg 2+ separation, offering valuable insights into the design and fabrication of advanced NF membranes for efficient Mg/Li separation.
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FOOD RESEARCH INTERNATIONAL
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2026
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IF 8
Xingying Xue,Zhiwen Qi,Hao Zhou,Ran Tao,Wenjun Li,Qin He,Jiandu Lei,Chengzhang Wang
A pulsed ultrasound-assisted deep eutectic solvent (DES) strategy enabled high-efficiency tannin extraction from chestnut burr waste, yielding 104.40 ± 4.31 mg TAE/g DW—2.1-fold higher than conventional aqueous extraction. Comprehensive mechanistic investigations revealed synergistic effects: DES components enhanced hydrogen bonding and electrostatic attraction with tannins, while a favorable solvation energy barrier (ΔG = −85.15 kcal/mol) facilitated extraction. Advanced spectroscopic analysis (FT-IR, HPLC-IT-TOF-MS 2 ) demonstrated DES-induced structural stabilization of hydrolysable tannins, with key components exhibiting a 3.1-fold increase in relative abundance. Specifically, DES was found to suppress water activity while forming protective tannin-DES complexes, as evidenced by characteristic upfield 1 H NMR shifts (Δδ = −0.19 ppm) and distinct vibrational frequency changes. The sustainability of this method was validated through five successful recycling trials and comprehensive green metric assessments. DES-extracted tannins demonstrated >1.2-fold enhanced antioxidant capacity and superior antibacterial activity compared to aqueous extracts. This work establishes an innovative method for agroforestry waste valorization and advances green extraction technologies.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.7
Hongping Li,Zehong Jin,Meilin Zhang,Lihua Fu,Baofeng Lin,Chuanhui Xu,Bai Huang
Traditional flexible conductive hydrogels use water as the dispersion medium, making them prone to freezing and cracking in low-temperature environments, rendering them unusable. Therefore, developing flexible materials that combine freeze resistance with high electrical conductivity to meet the demands of signal monitoring and energy storage in severe cold conditions is crucial for expanding the application boundaries of flexible wearable devices. This paper reports an effective strategy for preparing a flexible, freeze-resistant, and highly conductive polyzwitterionic eutectogel based on renewable nanocellulose. This strategy utilizes a three-dimensional cellulose network constructed via ionic crosslinking as the functional filler framework. Sulfonated betaine zwitterionic DMAPS ([2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide) is then in situ polymerized within this network to produce a dual-network composite eutectogel featuring both physical and chemical crosslinking interactions. The uniformly coexisting cellulose-Al 3+ network and polyzwitterionic network provide the structural foundation for energy dissipation and ion migration. Consequently, eutectogels exhibits excellent tensile properties and high electrical conductivity (0.25–0.71 S·m −1 ). The incorporation of deep eutectic solvents (DES) endows gels with exceptional antifreeze properties, maintaining excellent stability and outstanding ionic conductivity (0.24–0.65 S·m −1 ) even under extreme conditions at −20 °C—virtually unchanged from its performance at room temperature (25 °C). Notably, the strain sensor based on eutectogels exhibits outstanding sensitivity performance both in low-temperature and ambient environments (GF = 2.70 at −20 °C and GF = 2.54 at 25 °C). This is attributed to the gel's ability to maintain its mechanical and electrical properties at low temperatures, demonstrating its potential for application under harsh conditions. Additionally, eutectogels have been successfully applied in pressure sensors and supercapacitors to monitor pressure signals and store energy. Overall, this study has developed a promising strategy for preparing functional, freeze-resistant green composite sensors for engineering applications.
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Frontiers in Bioengineering and Biotechnology
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2026
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IF 4.8
Xiang Meng,Muzhou Xue,Zequn Zeng,Wenbin Pei,Bing Gong
Introduction: Bacterial wound infections that lead to sepsis pose a major clinical challenge. This study aims to develop and optimize a novel cross-linked poly(acrylic acid)/carboxymethylcellulose sodium (PAA/CMC-Na) hydrogel encapsulating liquiritigenin (LQ) to improve wound healing and infection control.Methods: The hydrogel matrix was optimized using response surface methodology (RSM). Mechanical properties, self-healing efficiency, and pH-responsive swelling behavior were characterized. In vitro drug release profiles were evaluated over 24 h, and molecular docking simulations were performed to assess the binding affinity of LQ to key sepsis targets. Biological safety was tested using CCK-8 and Trypan blue assays, while anti-inflammatory and antibacterial activities were evaluated using LPS-stimulated RAW264.7 macrophages and pathogen inhibition assays (E. coli and S. aureus).Results: The optimized hydrogel achieved a high model fit (R2 = 0.976$) and exhibited superior mechanical performance, including 776% tensile strain and 100% self-healing efficiency. Swelling was pH-responsive (∼600% at pH 5.5 vs. ∼450% at pH 7.4). LQ showed sustained release (>90% over 24 hours) and strong binding affinity to sepsis-related targets. Biological assays confirmed high biocompatibility (>98% fibroblast viability). Furthermore, the hydrogel significantly reduced inflammatory cytokines (TNF-α, IL-6, IL-1β) in a dose-dependent manner and effectively inhibited the growth of E. coli and S. aureus.Discussion: These findings demonstrate that the LQ-loaded hydrogel possesses excellent mechanical, biocompatible, and anti-inflammatory properties. Its dual-action as a pro-healing and antibacterial agent suggests it is a promising candidate for topical wound management and the prevention of infection-induced sepsis.
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MOLECULES
·
2026
·Vol. 31
·期 2
·210
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IF 4.6
Qi Chen,Shuaiwei Cui,Wenwen Zhang,Gang Dong,Baoshan Tang,Jinju Ma,Juan Xu,Jun Zhang,Lanxiang Liu
Gallic acid (GA) exhibits excellent antioxidant properties but suffers from chemical instability due to its carboxyl group, which limits practical application. To address this, we designed and investigated 14 distinct ester derivatives of GA, which were categorized into two major groups based on their substituents: chain alkyl and hydroxyl-substituted alkyl groups. Systematic evaluation revealed a striking decline in the DPPH radical scavenging activity of alkyl esters with increasing carbon chain length, from 91.9% for GA-C3 to 55.6% for GA-C30. The hydroxyl-functionalized GA esters GA-EG, GA-GL, and GA-PT maintain high antioxidant activity (>90%) while improving applicability through carboxyl substitution. In the oil system, all derivatives significantly prolong the oxidation induction time, with GA-C3 exhibiting the highest performance by extending the induction time by 2.15 h. Hydroxyl-functionalized esters such as GA-EG, GA-GL, and GA-PT also demonstrated significant efficacy, prolonging oxidation induction by 1.92 to 2.03 h. The results suggest how the structure of GA esters affects their antioxidant behavior, providing a direction for designing antioxidants suitable for specific systems.
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